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  1. Article ; Online: Cell size: Single cells illuminate the rules of cell size control.

    Olson, Bradley J S C

    Current biology : CB

    2023  Volume 33, Issue 23, Page(s) R1231–R1234

    Abstract: A new study uses Chlamydomonas reinhardtii to understand how cell size homeostasis emerges from stochastic individual cell behaviors within a population. The authors find that a simple power law model was a poor predictor of cell size regulation; rather, ...

    Abstract A new study uses Chlamydomonas reinhardtii to understand how cell size homeostasis emerges from stochastic individual cell behaviors within a population. The authors find that a simple power law model was a poor predictor of cell size regulation; rather, it is better explained by a modified threshold model.
    MeSH term(s) Chlamydomonas reinhardtii/physiology ; Cell Size ; Homeostasis
    Language English
    Publishing date 2023-12-05
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 1071731-6
    ISSN 1879-0445 ; 0960-9822
    ISSN (online) 1879-0445
    ISSN 0960-9822
    DOI 10.1016/j.cub.2023.10.045
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Estimation of Aquifer Transmissivity From Analysis of Long-Term Monitoring With the Thiem Solution.

    Henry, Joel C / Neville, Christopher J / Olson, Alyssa N

    Ground water

    2023  Volume 62, Issue 2, Page(s) 295–302

    Abstract: The application of the Thiem equation to support the interpretation of comprehensive long-term monitoring datasets, made possible through modern datalogging technology, is presented as an alternative to constant-rate aquifer testing to obtain ... ...

    Abstract The application of the Thiem equation to support the interpretation of comprehensive long-term monitoring datasets, made possible through modern datalogging technology, is presented as an alternative to constant-rate aquifer testing to obtain representative transmissivity estimates in settings where controlled hydraulic testing may be impractical. Water levels logged at regular intervals can be readily converted to average water levels over time periods corresponding to periods of known pumping rates. By regressing average water levels during multiple time periods of known but variable withdrawal rates, steady-state conditions can be approximated and Thiem's solution applied to estimate transmissivity, without performance of a constant-rate aquifer test. Although the application is limited to settings where changes in aquifer storage are negligible, by regressing long data sets to parse interferences the method may characterize aquifer conditions over a much wider radius than short-term, non-equilibrium tests. As with all aquifer testing, informed interpretation is critical to identifying and resolving aquifer heterogeneities and interferences.
    MeSH term(s) Groundwater ; Models, Theoretical ; Water Movements ; Water Supply ; Water
    Chemical Substances Water (059QF0KO0R)
    Language English
    Publishing date 2023-06-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 246212-6
    ISSN 1745-6584 ; 0017-467X
    ISSN (online) 1745-6584
    ISSN 0017-467X
    DOI 10.1111/gwat.13332
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: A Perovskite-Graphene Device for X-ray Detection.

    Snow, J / Olson, C / Torres, E / Shirley, K / Cazalas, E

    Carbon

    2023  Volume 216

    Abstract: This study examines a perovskite-based graphene field effect transistor (P-GFET) device for X-ray detection. The device architecture consisted of a commercially available GFET-S20 chip, produced by Graphenea, with a layer of methylammonium lead iodide ( ... ...

    Abstract This study examines a perovskite-based graphene field effect transistor (P-GFET) device for X-ray detection. The device architecture consisted of a commercially available GFET-S20 chip, produced by Graphenea, with a layer of methylammonium lead iodide (MAPbI
    Language English
    Publishing date 2023-11-01
    Publishing country United States
    Document type Journal Article
    ISSN 0008-6223
    ISSN 0008-6223
    DOI 10.1016/j.carbon.2023.118586
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Effect of RMGI Roughness and Dentin Bonding Primer on Shear Bond Strength of Sandwich-type Restorations.

    Bloomquist, R / Villalobos, V / Patel, C / Olson, J / Rueggeberg, F

    Operative dentistry

    2023  Volume 48, Issue 5, Page(s) 546–551

    Abstract: Background: The open sandwich technique is a reliable alternative to amalgam placement in deep proximal box preparations, where proper isolation and enamel bonding may not be possible. It is often difficult to prepare the box for composite placement ... ...

    Abstract Background: The open sandwich technique is a reliable alternative to amalgam placement in deep proximal box preparations, where proper isolation and enamel bonding may not be possible. It is often difficult to prepare the box for composite placement without affecting the resin-modified glass ionomer (RMGI) that has been placed in the gingival portion. We hypothesized that RMGI surfaces that are roughened or those that use all steps in the manufacturing bonding protocol, including the priming solution, applied before placing a bonded composite increment, would have greater composite/RMGI shear bond strength.
    Design and methods: Shear bond strengths (SBS) of RMGI tested in the presence and absence of SiC roughening and primer-coating were tested using a fourth-generation dentin bonding agent to composite after thermocycling. Twenty specimens for four test conditions were fabricated and investigated. Data were subjected to a two-way ANOVA and the Holm-Sidak post-hoc test.
    Results: Placing dentin primer on unabraded RMGI provided a statistically significant improvement in SBS, but only modestly. Furthermore, because bond failure consistently occurred within the RMGI itself, none of the surface modifications have a clinically relevant impact on SBS at the RMGI to the composite interface.
    Conclusions: Clinicians should be aware that they need not avoid RMGI abrasion and do not need to incorporate all components of a fourth-generation bonding system when covering an RMGI sandwich layer with composite.
    MeSH term(s) Dental Bonding/methods ; Composite Resins/chemistry ; Silicon Dioxide/chemistry ; Dentin ; Materials Testing ; Shear Strength ; Resin Cements/chemistry ; Surface Properties ; Dentin-Bonding Agents/chemistry
    Chemical Substances glass ionomer ; Composite Resins ; Silicon Dioxide (7631-86-9) ; Resin Cements ; Dentin-Bonding Agents
    Language English
    Publishing date 2023-07-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 752995-8
    ISSN 1559-2863 ; 0361-7734
    ISSN (online) 1559-2863
    ISSN 0361-7734
    DOI 10.2341/22-130-L
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Telemedicine: Progress Toward Optimizing Care Delivery (Let's Not Regress).

    Chuo, John / Olson, Christina

    Hospital pediatrics

    2022  Volume 13, Issue 1, Page(s) e17–e19

    MeSH term(s) Humans ; Infant, Newborn ; Follow-Up Studies ; Intensive Care Units, Neonatal ; Delivery of Health Care ; Telemedicine ; Ambulatory Care Facilities
    Language English
    Publishing date 2022-12-09
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2154-1671
    ISSN (online) 2154-1671
    DOI 10.1542/hpeds.2022-007002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Flipping the Null: Lessons From Breast Cancer and Recalibrating Expectations in Oligometastases.

    Katipally, Rohan R / Olson, Adam C / Chmura, Steven J

    International journal of radiation oncology, biology, physics

    2022  Volume 114, Issue 5, Page(s) 840–842

    MeSH term(s) Humans ; Female ; Breast Neoplasms ; Motivation ; Radiosurgery ; Lung Neoplasms/secondary
    Language English
    Publishing date 2022-11-14
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 197614-x
    ISSN 1879-355X ; 0360-3016
    ISSN (online) 1879-355X
    ISSN 0360-3016
    DOI 10.1016/j.ijrobp.2022.09.055
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Learned linear models for detecting watercraft in a maritime environment.

    Olson, C C / Nichols, J M

    Applied optics

    2020  Volume 59, Issue 25, Page(s) 7553–7559

    Abstract: This work provides a new, to the best of our knowledge, approach to constructing linear models for object detection in a scene. Specifically, we use representative training data in order to estimate the parameters describing a generalized wavelet model ... ...

    Abstract This work provides a new, to the best of our knowledge, approach to constructing linear models for object detection in a scene. Specifically, we use representative training data in order to estimate the parameters describing a generalized wavelet model for the express purpose of detecting the presence of maritime targets in a scene. The parameter estimates are taken as those that maximize the probability of detecting the targets for a fixed probability of false alarm. The approach is then demonstrated on a database of short-wave infrared imagery containing various watercraft. Results are then compared to some of the more standard wavelet bases used in detection applications.
    Language English
    Publishing date 2020-09-09
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4522
    ISSN (online) 1539-4522
    DOI 10.1364/AO.396496
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Role of Terlipressin in Patients With Hepatorenal Syndrome-Acute Kidney Injury Admitted to the ICU: A Substudy of the CONFIRM Trial.

    Karvellas, Constantine J / Subramanian, Ram / Olson, Jody C / Jamil, Khurram

    Critical care explorations

    2023  Volume 5, Issue 4, Page(s) e0890

    Abstract: This study assessed the potential advantages of treating hepatorenal syndrome-acute kidney injury (HRS-AKI) with terlipressin versus placebo in the ICU setting.: Design: Patients were randomly assigned in a 2:1 ratio to receive terlipressin or placebo ...

    Abstract This study assessed the potential advantages of treating hepatorenal syndrome-acute kidney injury (HRS-AKI) with terlipressin versus placebo in the ICU setting.
    Design: Patients were randomly assigned in a 2:1 ratio to receive terlipressin or placebo for up to 14 days.
    Setting: A retrospective analysis of data from the phase III CONFIRM study.
    Participants: Adult patients with HRS-AKI admitted to the ICU.
    Main outcomes and measures: In this substudy, we evaluated outcomes of the ICU stay and the need for organ support, including renal replacement therapy (RRT).
    Results: Among 300 patients with HRS-AKI from the CONFIRM study, 45 were treated in the ICU (terlipressin, 31/199 [16%]; placebo, 14/101 [14%]). On ICU admission, baseline demographics were similar across treatment arms, including severity of liver dysfunction. Among patients alive at the end of the ICU stay, those randomized to terlipressin had a significantly shorter median length of ICU stay than placebo (4 vs 11 d;
    Conclusions: In this subanalysis of CONFIRM, patients admitted to the ICU with HRS-AKI who received terlipressin were more likely to achieve renal function improvement, based on serum creatinine changes by the end of treatment, and had significantly shorter lengths of ICU stay than patients randomized to the placebo arm.
    Language English
    Publishing date 2023-03-28
    Publishing country United States
    Document type Journal Article
    ISSN 2639-8028
    ISSN (online) 2639-8028
    DOI 10.1097/CCE.0000000000000890
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: The Curious Case of Multicellularity in the Volvocine Algae.

    Jiménez-Marín, Berenice / Olson, Bradley J S C

    Frontiers in genetics

    2022  Volume 13, Page(s) 787665

    Abstract: The evolution of multicellularity is a major evolutionary transition that underlies the radiation of many species in all domains of life, especially in eukaryotes. The volvocine green algae are an unconventional model system that holds great promise in ... ...

    Abstract The evolution of multicellularity is a major evolutionary transition that underlies the radiation of many species in all domains of life, especially in eukaryotes. The volvocine green algae are an unconventional model system that holds great promise in the field given its genetic tractability, late transition to multicellularity, and phenotypic diversity. Multiple efforts at linking multicellularity-related developmental landmarks to key molecular changes, especially at the genome level, have provided key insights into the molecular innovations or lack thereof that underlie multicellularity. Twelve developmental changes have been proposed to explain the evolution of complex differentiated multicellularity in the volvocine algae. Co-option of key genes, such as cell cycle and developmental regulators has been observed, but with few exceptions, known co-option events do not seem to coincide with most developmental features observed in multicellular volvocines. The apparent lack of "master multicellularity genes" combined with no apparent correlation between gene gains for developmental processes suggest the possibility that many multicellular traits might be the product gene-regulatory and functional innovations; in other words, multicellularity can arise from shared genomic repertoires that undergo regulatory and functional overhauls.
    Language English
    Publishing date 2022-02-15
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2022.787665
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A cryptic natural variant allele of BYPASS2 suppresses the bypass1 mutant phenotype.

    Cummins, Alexander J / Siler, C J / Olson, Jacob M / Kaur, Amanpreet / Hamdani, Adam K / Olson, L Kate / Dilkes, Brian P / Sieburth, Leslie E

    Plant physiology

    2023  Volume 192, Issue 2, Page(s) 1016–1027

    Abstract: The Arabidopsis (Arabidopsis thaliana) BYPASS1 (BPS1) gene encodes a protein with no functionally characterized domains, and loss-of-function mutants (e.g. bps1-2 in Col-0) present a severe growth arrest phenotype that is evoked by a root-derived graft- ... ...

    Abstract The Arabidopsis (Arabidopsis thaliana) BYPASS1 (BPS1) gene encodes a protein with no functionally characterized domains, and loss-of-function mutants (e.g. bps1-2 in Col-0) present a severe growth arrest phenotype that is evoked by a root-derived graft-transmissible small molecule that we call dalekin. The root-to-shoot nature of dalekin signaling suggests it could be an endogenous signaling molecule. Here, we report a natural variant screen that allowed us to identify enhancers and suppressors of the bps1-2 mutant phenotype (in Col-0). We identified a strong semi-dominant suppressor in the Apost-1 accession that largely restored shoot development in bps1 and yet continued to overproduce dalekin. Using bulked segregant analysis and allele-specific transgenic complementation, we showed that the suppressor is the Apost-1 allele of a BPS1 paralog, BYPASS2 (BPS2). BPS2 is one of four members of the BPS gene family in Arabidopsis, and phylogenetic analysis demonstrated that the BPS family is conserved in land plants and the four Arabidopsis paralogs are retained duplicates from whole genome duplications. The strong conservation of BPS1 and paralogous proteins throughout land plants, and the similar functions of paralogs in Arabidopsis, suggests that dalekin signaling might be retained across land plants.
    MeSH term(s) Alleles ; Arabidopsis/metabolism ; Arabidopsis Proteins/genetics ; Arabidopsis Proteins/metabolism ; Phenotype ; Phylogeny ; Plant Roots/metabolism
    Chemical Substances Arabidopsis Proteins ; BYPASS1 protein, Arabidopsis ; AT2G46080 protein, Arabidopsis
    Language English
    Publishing date 2023-03-11
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 208914-2
    ISSN 1532-2548 ; 0032-0889
    ISSN (online) 1532-2548
    ISSN 0032-0889
    DOI 10.1093/plphys/kiad124
    Database MEDical Literature Analysis and Retrieval System OnLINE

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