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  1. Article ; Online: Increasing Divergence in Spirometry Recommendations.

    Graham, Brian L / Stanojevic, Sanja / Miller, Martin R

    Chest

    2023  Volume 164, Issue 6, Page(s) 1361–1363

    Language English
    Publishing date 2023-11-20
    Publishing country United States
    Document type Editorial
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2023.06.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui III Zs.45: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 349: Show issues

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  2. Article ; Online: Metal-Ligand Exchange Coupling Alters the Open-Shell Ligand Electronic Structure in a Bis(semiquinone) Complex.

    Miller, Paul D / Mengell, Joshua / Shultz, David A / Kirk, Martin L

    Inorganic chemistry

    2024  Volume 63, Issue 14, Page(s) 6493–6499

    Abstract: The electronic structure of the bis(dioxolene) bridging ligand - ...

    Abstract The electronic structure of the bis(dioxolene) bridging ligand -
    Language English
    Publishing date 2024-03-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1484438-2
    ISSN 1520-510X ; 0020-1669
    ISSN (online) 1520-510X
    ISSN 0020-1669
    DOI 10.1021/acs.inorgchem.4c00380
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  3. Article ; Online: Reconciling the past and considering the future of pulmonary function test interpretation.

    Dinh-Xuan, Anh Tuan / Graham, Brian L / Thompson, Bruce / Miller, Martin R / Stanojevic, Sanja

    The European respiratory journal

    2024  Volume 63, Issue 2

    MeSH term(s) Humans ; Respiratory Function Tests ; Forecasting
    Language English
    Publishing date 2024-02-01
    Publishing country England
    Document type Editorial
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.02225-2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2322: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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    Zs.MO 292: Show issues

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  4. Article ; Online: Do American Thoracic Society and European Respiratory Society Journals Have a Role in Promoting Official American Thoracic Society and European Respiratory Society Standards?

    Miller, Martin R / Stanojevic, Sanja / Graham, Brian L

    Annals of the American Thoracic Society

    2023  Volume 20, Issue 12, Page(s) 1694–1696

    MeSH term(s) Humans ; United States ; Periodicals as Topic ; Reference Standards ; Societies
    Language English
    Publishing date 2023-09-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2717461-X
    ISSN 2325-6621 ; 1943-5665 ; 2325-6621
    ISSN (online) 2325-6621 ; 1943-5665
    ISSN 2325-6621
    DOI 10.1513/AnnalsATS.202307-612VP
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    Zs.A 5828: Show issues Location:
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  5. Article ; Online: Drug Approval for the Treatment of Geographic Atrophy: How We Got Here and Where We Need to Go.

    Csaky, Karl G / Miller, Jason M L / Martin, Daniel F / Johnson, Mark W

    American journal of ophthalmology

    2024  Volume 263, Page(s) 231–239

    Abstract: Purpose: To discuss the clinical trial results leading to the US Food and Drug Administration (FDA) approval of anti-complement therapies for geographic atrophy (GA), perspectives on functional data from the GA clinical trials, and how lessons from the ... ...

    Abstract Purpose: To discuss the clinical trial results leading to the US Food and Drug Administration (FDA) approval of anti-complement therapies for geographic atrophy (GA), perspectives on functional data from the GA clinical trials, and how lessons from the FDA approval may guide future directions for basic and clinical research in AMD.
    Design: Selected literature review with analysis and perspective METHODS: We performed a targeted review of publicly available data from the clinical trials of pegcetacoplan and avacincaptad for the treatment of GA, as well as scientific literature on the natural history of GA and the genetics and basic science of complement in AMD.
    Results: The approval of pegcetacoplan and avacincaptad was based on an anatomic endpoint of a reduction in the rate of GA expansion over time. However, functional data from 2 phase 3 clinical trials for each drug demonstrated no visual benefit to patients in the treatment groups. Review of the genetics of AMD and the basic science of the role for complement in AMD provides only modest support for targeting complement as treatment for GA expansion, and alternative molecular targets for GA treatment are therefore discussed. Reasons for the disconnect between anatomic and functional outcomes in the clinical trials of anti-complement therapies are discussed, providing insight to guide the configuration of future clinical studies for GA.
    Conclusion: Although avacincaptad and pegcetacoplan are our first FDA-approved treatments for GA, results from the clinical trials failed to show any functional improvement after 1 and 2 years, respectively, calling into question whether the drugs represent a "clinically relevant outcome." To improve the chances of more impactful therapies in the future, we provide basic-science rationale for pursuing non-complement targets; emphasize the importance of ongoing clinical research that more closely pins anatomic features of GA to functional outcomes; and provide suggestions for clinical endpoints for future clinical trials on GA.
    Language English
    Publishing date 2024-02-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80030-2
    ISSN 1879-1891 ; 0002-9394
    ISSN (online) 1879-1891
    ISSN 0002-9394
    DOI 10.1016/j.ajo.2024.02.021
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  6. Article ; Online: Addressing the effect of ancestry on lung volume.

    Graham, Brian L / Miller, Martin R / Thompson, Bruce R

    The European respiratory journal

    2022  Volume 59, Issue 6

    MeSH term(s) Humans ; Lung/diagnostic imaging ; Lung Volume Measurements ; Vital Capacity
    Language English
    Publishing date 2022-06-16
    Publishing country England
    Document type Editorial
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.00882-2022
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    Zs.A 2322: Show issues Location:
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    Zs.MO 292: Show issues

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  7. Article ; Online: Latine Transgender/Gender Diverse Adolescents: Protective Factors Against Emotional Distress.

    McPherson, Lauren E / Svetaz, Maria Veronica / Martin, Christie L / Miller, Kathleen K / Eisenberg, Marla E

    LGBT health

    2023  Volume 10, Issue 3, Page(s) 220–227

    Abstract: Purpose: ...

    Abstract Purpose:
    MeSH term(s) Humans ; Adolescent ; Transgender Persons ; Protective Factors ; Cross-Sectional Studies ; Suicide, Attempted ; Psychological Distress
    Language English
    Publishing date 2023-02-16
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 2727303-9
    ISSN 2325-8306 ; 2325-8292
    ISSN (online) 2325-8306
    ISSN 2325-8292
    DOI 10.1089/lgbt.2022.0068
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  8. Article ; Online: Race/Ethnicity and Reference Equations for Spirometry.

    Miller, Martin R / Graham, Brian L / Thompson, Bruce R

    American journal of respiratory and critical care medicine

    2022  Volume 206, Issue 6, Page(s) 790–792

    MeSH term(s) Ethnicity ; Forced Expiratory Volume ; Humans ; Lung ; Reference Values ; Spirometry ; Vital Capacity
    Language English
    Publishing date 2022-04-19
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202201-0197LE
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  9. Article: Variation from closed-shell to open shell electronic structures in oligothiophene bis(dioxolene) complexes.

    Miller, Paul D / Shultz, David A / Mengell, Joshua / Kirk, Martin L / Wojtas, Lukasz

    Chemical science

    2023  Volume 14, Issue 43, Page(s) 12264–12276

    Abstract: A series of oligothiophene bis(dioxolene) complexes, SQ- ... ...

    Abstract A series of oligothiophene bis(dioxolene) complexes, SQ-Th
    Language English
    Publishing date 2023-10-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2559110-1
    ISSN 2041-6539 ; 2041-6520
    ISSN (online) 2041-6539
    ISSN 2041-6520
    DOI 10.1039/d3sc02341a
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  10. Book ; Online: The Extent of Restrictions on the Service of Active-Component Military Women

    Miller, Laura L / Kavanagh, Jennifer / Lytell, Maria C / Jennings, Keith / Martin, Craig

    2012  

    Keywords Advice on careers & achieving success ; Personnel & human resources management ; Management & management techniques ; Defence strategy, planning & research ; History ; Management & Organizational Behavior ; Sociology ; Business
    Language English
    Size 1 Online-Ressource
    Publisher RAND Corporation
    Document type Book ; Online
    Note English
    HBZ-ID HT030612953
    ISBN 9780833059697 ; 0833059696
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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