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  1. Article ; Online: Vascular injury of the supra-aortic trunks in patients with traumatic brain injury.

    Ferrete-Araujo, Ana María / Godoy, Daniel A / Murillo-Cabezas, Francisco

    Medicina intensiva

    2023  Volume 47, Issue 7, Page(s) 411–413

    MeSH term(s) Humans ; Vascular System Injuries ; Aorta ; Aorta, Thoracic ; Brain Injuries, Traumatic/complications
    Language English
    Publishing date 2023-03-23
    Publishing country Spain
    Document type Case Reports
    ISSN 2173-5727
    ISSN (online) 2173-5727
    DOI 10.1016/j.medine.2023.03.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Evolutionary conceptualization of the injury mechanisms intraumatic brain injury.

    Godoy, D A / Murillo-Cabezas, F

    Medicina intensiva

    2021  Volume 46, Issue 2, Page(s) 90–93

    MeSH term(s) Brain Injuries/etiology ; Concept Formation ; Humans
    Language English
    Publishing date 2021-12-06
    Publishing country Spain
    Document type Journal Article
    ISSN 2173-5727
    ISSN (online) 2173-5727
    DOI 10.1016/j.medine.2021.11.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Ten physiological commandments for severe head injury.

    Godoy, D A / Badenes, R / Murillo-Cabezas, F

    Revista espanola de anestesiologia y reanimacion

    2021  Volume 68, Issue 5, Page(s) 280–292

    Abstract: Advances in multiparametric brain monitoring have allowed us to deepen our knowledge of the physiopathology of head injury and how it can be treated using the therapies available today. It is essential to understand and interpret a series of basic ... ...

    Abstract Advances in multiparametric brain monitoring have allowed us to deepen our knowledge of the physiopathology of head injury and how it can be treated using the therapies available today. It is essential to understand and interpret a series of basic physiological and physiopathological principles that, on the one hand, provide an adequate metabolic environment to prevent worsening of the primary brain injury and favour its recovery, and on the other hand, allow therapeutic resources to be individually adapted to the specific needs of the patient. Based on these notions, this article presents a decalogue of the physiological objectives to be achieved in brain injury, together with a series of diagnostic and therapeutic recommendations for achieving these goals. We emphasise the importance of considering and analysing the physiological variables involved in the transport of oxygen to the brain, such as cardiac output and arterial oxygen content, together with their conditioning factors and possible alterations. Special attention is paid to the basic elements of physiological neuroprotection, and we describe the multiple causes of cerebral hypoxia, how to approach them, and how to correct them. We also examine the increase in intracranial pressure as a physiopathological element, focussing on the significance of thoracic and abdominal pressure in the interpretation of intracranial pressure. Treatment of intracranial pressure should be based on a step-wise model, the first stage of which should be based on a physiopathological reflection combined with information on the tomographic lesions rather than on rigid numerical values.
    MeSH term(s) Brain/diagnostic imaging ; Brain Injuries/therapy ; Humans ; Hypoxia, Brain ; Intracranial Pressure ; Oxygen
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2021-05-15
    Publishing country Spain
    Document type Journal Article
    ISSN 2341-1929
    ISSN (online) 2341-1929
    DOI 10.1016/j.redare.2020.09.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Ten physiological commandments for severe head injury.

    Godoy, D A / Badenes, R / Murillo-Cabezas, F

    Revista espanola de anestesiologia y reanimacion

    2021  Volume 68, Issue 5, Page(s) 280–292

    Abstract: Advances in multiparametric brain monitoring have allowed us to deepen our knowledge of the physiopathology of head injury and how it can be treated using the therapies available today. It is essential to understand and interpret a series of basic ... ...

    Title translation Diez mandamientos fisiológicos a lograr durante el traumatismo craneoencefálico grave.
    Abstract Advances in multiparametric brain monitoring have allowed us to deepen our knowledge of the physiopathology of head injury and how it can be treated using the therapies available today. It is essential to understand and interpret a series of basic physiological and physiopathological principles that, on the one hand, provide an adequate metabolic environment to prevent worsening of the primary brain injury and favour its recovery, and on the other hand, allow therapeutic resources to be individually adapted to the specific needs of the patient. Based on these notions, this article presents a decalogue of the physiological objectives to be achieved in brain injury, together with a series of diagnostic and therapeutic recommendations for achieving these goals. We emphasise the importance of considering and analysing the physiological variables involved in the transport of oxygen to the brain, such as cardiac output and arterial oxygen content, together with their conditioning factors and possible alterations. Special attention is paid to the basic elements of physiological neuroprotection, and we describe the multiple causes of cerebral hypoxia, how to approach them, and how to correct them. We also examine the increase in intracranial pressure as a physiopathological element, focussing on the significance of thoracic and abdominal pressure in the interpretation of intracranial pressure. Treatment of intracranial pressure should be based on a step-wise model, the first stage of which should be based on a physiopathological reflection combined with information on the tomographic lesions rather than on rigid numerical values.
    Language Spanish
    Publishing date 2021-01-21
    Document type Journal Article
    ISSN 2341-1929
    ISSN (online) 2341-1929
    DOI 10.1016/j.redar.2020.09.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Evolutionary conceptualization of the injury mechanisms intraumatic brain injury.

    Godoy, D A / Murillo-Cabezas, F

    Medicina intensiva

    2020  

    Title translation Conceptualización evolutiva de los mecanismos lesionales en el traumatismo craneoencefálico.
    Language Spanish
    Publishing date 2020-03-16
    Publishing country Spain
    Document type Journal Article
    ISSN 2173-5727
    ISSN (online) 2173-5727
    DOI 10.1016/j.medin.2020.02.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: High-flow oxygen therapy in acute hypoxemic respiratory failure secondary to COVID-19 pneumonia.

    Godoy, D A / Graneros, N / Oyarzabal, L / Murillo-Cabezas, F

    Medicina intensiva

    2021  

    Title translation Oxigenoterapia de alto flujo en insuficiencia respiratoria aguda hipoxémica secundaria a neumonía por COVID-19.
    Language Spanish
    Publishing date 2021-02-18
    Publishing country Spain
    Document type Letter
    ISSN 2173-5727
    ISSN (online) 2173-5727
    DOI 10.1016/j.medin.2021.02.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: High-flow oxygen therapy in acute hypoxemic respiratory failure secondary to COVID-19 pneumonia.

    Godoy, D A / Graneros, N / Oyarzabal, L / Murillo-Cabezas, F

    Medicina intensiva

    2021  Volume 45, Issue 8, Page(s) 506–508

    MeSH term(s) COVID-19 ; Humans ; Oxygen ; Oxygen Inhalation Therapy ; Respiratory Insufficiency/etiology ; SARS-CoV-2
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2021-08-21
    Publishing country Spain
    Document type Letter ; Comment
    ISSN 2173-5727
    ISSN (online) 2173-5727
    DOI 10.1016/j.medine.2021.08.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Tiempo y entrenamiento: claves del éxito en el tratamiento del ictus isquémico agudo.

    Murillo-Cabezas, F

    Medicina intensiva

    2012  Volume 36, Issue 5, Page(s) 319–321

    Title translation Time and training: keys to success in the treatment of acute ischemic stroke.
    MeSH term(s) Brain Ischemia/drug therapy ; Computer Simulation ; Fibrinolytic Agents/therapeutic use ; Humans ; Models, Theoretical ; Patient Transfer ; Referral and Consultation ; Thrombolytic Therapy
    Chemical Substances Fibrinolytic Agents
    Language Spanish
    Publishing date 2012-06
    Publishing country Spain
    Document type Comment ; Editorial
    ZDB-ID 731753-0
    ISSN 1578-6749 ; 0210-5691
    ISSN (online) 1578-6749
    ISSN 0210-5691
    DOI 10.1016/j.medin.2012.03.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Pandemia de Covid-19 y transformación digital en Cuidados Intensivos.

    Murillo-Cabezas, F / Vigil-Martín, E / Raimondi, N / Pérez-Fernández, J

    Medicina intensiva

    2020  Volume 44, Issue 7, Page(s) 457–458

    Title translation Covid-19 pandemic and digital transformation in critical care units.
    MeSH term(s) Betacoronavirus ; Big Data ; COVID-19 ; Computer Systems ; Coronavirus Infections ; Critical Care/methods ; Electronic Health Records/trends ; Health Services Needs and Demand ; Hospital Information Systems/trends ; Humans ; Infection Control ; Intensive Care Units ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2 ; Telemedicine/methods ; Telemedicine/trends
    Keywords covid19
    Language Spanish
    Publishing date 2020-04-15
    Publishing country Spain
    Document type Journal Article
    ISSN 2173-5727
    ISSN (online) 2173-5727
    DOI 10.1016/j.medin.2020.04.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: RhoA in aneurysmal subarachnoid hemorrhage.

    Ureña, Juan / González-Montelongo, María Del Carmen / Murillo-Cabezas, Francisco

    Aging

    2019  Volume 11, Issue 4, Page(s) 1079–1080

    MeSH term(s) Adult ; Humans ; Middle Aged ; Subarachnoid Hemorrhage/metabolism ; Subarachnoid Hemorrhage/pathology ; rhoA GTP-Binding Protein/metabolism
    Chemical Substances RHOA protein, human (124671-05-2) ; rhoA GTP-Binding Protein (EC 3.6.5.2)
    Language English
    Publishing date 2019-02-07
    Publishing country United States
    Document type Editorial
    ISSN 1945-4589
    ISSN (online) 1945-4589
    DOI 10.18632/aging.101819
    Database MEDical Literature Analysis and Retrieval System OnLINE

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