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  1. Article: Metformin, cancer, COVID-19, and longevity.

    Kostev, Karel

    International journal of clinical pharmacology and therapeutics

    2023  Volume 61, Issue 3, Page(s) 93–95

    MeSH term(s) Humans ; Metformin/adverse effects ; Longevity ; COVID-19 ; Hypoglycemic Agents/adverse effects ; Neoplasms/drug therapy ; Neoplasms/epidemiology ; Diabetes Mellitus, Type 2/diagnosis ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/epidemiology
    Chemical Substances Metformin (9100L32L2N) ; Hypoglycemic Agents
    Language English
    Publishing date 2023-01-02
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 124384-6
    ISSN 0946-1965 ; 0340-0026 ; 0300-9718 ; 0174-4879
    ISSN 0946-1965 ; 0340-0026 ; 0300-9718 ; 0174-4879
    DOI 10.5414/CP204390
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 467: Show issues Location:
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  2. Article ; Online: Sex-Related Differences in the Association Between Body Mass Index and Dementia Risk.

    Kostev, Karel

    Journal of Alzheimer's disease : JAD

    2023  Volume 94, Issue 3, Page(s) 961–962

    Abstract: In this issue, Zakharova et al. report on important findings concerning the association between body mass index and dementia risk as related to sex. Concretely, underweight was strongly associated with dementia risk in men but not in women. We compare ... ...

    Abstract In this issue, Zakharova et al. report on important findings concerning the association between body mass index and dementia risk as related to sex. Concretely, underweight was strongly associated with dementia risk in men but not in women. We compare the results of this study with a recent publication by Jacob et al. and consider the role of sex in the association between body mass index and dementia.
    MeSH term(s) Male ; Humans ; Female ; Body Mass Index ; Dementia/epidemiology ; Risk Factors ; Alzheimer Disease
    Language English
    Publishing date 2023-07-09
    Publishing country Netherlands
    Document type Journal Article ; Comment
    ZDB-ID 1440127-7
    ISSN 1875-8908 ; 1387-2877
    ISSN (online) 1875-8908
    ISSN 1387-2877
    DOI 10.3233/JAD-230598
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6084: Show issues Location:
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  3. Article ; Online: Frequency of over- and under-treatment with levothyroxine in primary care in Germany.

    Kostev, Karel

    European journal of endocrinology

    2022  Volume 186, Issue 3, Page(s) L5

    MeSH term(s) Germany ; Humans ; Hypothyroidism/drug therapy ; Primary Health Care ; Thyrotropin ; Thyroxine/therapeutic use
    Chemical Substances Thyrotropin (9002-71-5) ; Thyroxine (Q51BO43MG4)
    Language English
    Publishing date 2022-02-03
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1183856-5
    ISSN 1479-683X ; 0804-4643
    ISSN (online) 1479-683X
    ISSN 0804-4643
    DOI 10.1530/EJE-21-0916
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  4. Article: Correction: Kostev, K.; Cai, T. Cystitis and Utipro

    Kostev, Karel / Cai, Tommaso

    Healthcare (Basel, Switzerland)

    2024  Volume 12, Issue 1

    Abstract: In the original publication [ ... ]. ...

    Abstract In the original publication [...].
    Language English
    Publishing date 2024-01-02
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare12010108
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: Medical care in Germany

    Kostev, Karel

    epidemiology, health economics and outcome research with IMS patient databases

    2011  

    Author's details ed. and publ. by Karel Kostev
    Keywords Medizinische Versorgung ; Pharmakotherapie ; Wirkungsanalyse ; Gesundheitsökonomie ; Epidemiologie ; Patient ; IMS
    Subject Information management system ; IBM IMS ; Patienten ; Krankheitsverbreitung ; Gesundheitsökonomik ; Gesundheitswesen ; Medizinökonomie ; Medizinökonomik ; Medizinische Ökonomie ; Medizinische Ökonomik ; Health Economics ; Arzneimitteltherapie ; Arzneitherapie ; Medikamentöse Therapie ; Gesundheitsversorgung ; Gesundheitliche Versorgung ; Patientenversorgung
    Subject code 362.10943 ; 615.580681
    Language English
    Size 144 S. : graph. Darst.
    Edition 1. Aufl.
    Publisher Optimus Mostafa Verl
    Publishing place Göttingen
    Publishing country Germany
    Document type Book
    HBZ-ID HT017140932
    ISBN 978-3-941274-90-7 ; 3-941274-90-2
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2012 A 1356 order for loan Magazin

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  6. Article ; Online: Reply to comment on: Association of glucose-lowering drugs with incident stroke and transient ischaemic attacks in primary care patients with type 2 diabetes: disease analyser database.

    Rathmann, Wolfgang / Kostev, Karel

    Acta diabetologica

    2024  

    Language English
    Publishing date 2024-04-02
    Publishing country Germany
    Document type Letter
    ZDB-ID 1097676-0
    ISSN 1432-5233 ; 0940-5429
    ISSN (online) 1432-5233
    ISSN 0940-5429
    DOI 10.1007/s00592-024-02272-7
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 611: Show issues Location:
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  7. Book ; Thesis: Datenbankbasierte epidemiologische Untersuchungen zur Behandlung von Patienten mit Diabetes mellitus in Deutschland

    Kostev, Karel

    Möglichkeiten der Anwendung von der Patientendatenbank "IMS® Disease Analyzer" in der medizinischen und epidemiologischen Forschung am Beispiel des Diabetes mellitus

    2010  

    Title variant IMS
    Author's details Karel Kostev
    Keywords Deutschland ; Diabetes mellitus ; Patient ; Datenbank ; Epidemiologie ; Forschung
    Subject Wissenschaftliche Forschung ; Forschungen ; Krankheitsverbreitung ; Datenbasis ; Informationsbank ; Datenbanken ; Patienten ; Diabetes verus ; Zuckerharnruhr ; Zuckerkrankheit
    Subject code 614.5946200285
    Language German
    Size 77 S. : Ill., graph. Darst., 21 cm
    Edition 1. Aufl.
    Publisher Optimus
    Publishing place Göttingen
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Leipzig, Univ., Diss., 2010
    HBZ-ID HT016713727
    ISBN 978-3-941274-44-0 ; 3-941274-44-9
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2011 A 733 order for loan Magazin

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  8. Article ; Online: Association of antihypertensives and Parkinson's disease in a primary care population matched for underlying diagnosis.

    Schrag, Anette / Kostev, Karel

    PloS one

    2024  Volume 19, Issue 3, Page(s) e0299985

    Abstract: Purpose: To examine the association of several antihypertensive medication classes with incidence of Parkinson's disease (PD), taking into account possible underlying conditions.: Methods: In a case-control study based on a large primary care ... ...

    Abstract Purpose: To examine the association of several antihypertensive medication classes with incidence of Parkinson's disease (PD), taking into account possible underlying conditions.
    Methods: In a case-control study based on a large primary care database and including 21,981 PD cases and 21,981 non-PD controls matched for age, sex, and possible treatment indications associations with different antihypertensive medication groups, including diuretics, betablockers, calcium channel blockers, angiotensin-converting enzyme inhibitors and angiotensin-II receptor-blockers and PD were examined.
    Results: Antihypertensive medications overall were associated with a lower risk of subsequent diagnosis of PD (OR: 0.94, 95% CI 0.90-0.97), with the negative association most significant for medications acting on the renin-angiotensin-aldosterone system. A positive association with diagnosis of PD was only seen for betablockers and restricted to those with relatively young age and not in those with longer treatment duration.
    Conclusion: When taking into account underlying diagnoses, antihypertensive medications overall were associated with a reduced incidence of PD.
    MeSH term(s) Humans ; Antihypertensive Agents/therapeutic use ; Antihypertensive Agents/pharmacology ; Case-Control Studies ; Parkinson Disease/diagnosis ; Parkinson Disease/drug therapy ; Parkinson Disease/epidemiology ; Hypertension/complications ; Hypertension/drug therapy ; Hypertension/epidemiology ; Calcium Channel Blockers/therapeutic use ; Primary Health Care ; Angiotensin Receptor Antagonists/therapeutic use
    Chemical Substances Antihypertensive Agents ; Calcium Channel Blockers ; Angiotensin Receptor Antagonists
    Language English
    Publishing date 2024-03-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0299985
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Correction

    Karel Kostev / Tommaso Cai

    Healthcare, Vol 12, Iss 1, p

    Kostev, K.; Cai, T. Cystitis and Utipro ® Plus: Real-World Evidence. Healthcare 2023, 11 , 2564

    2024  Volume 108

    Abstract: In the original publication [.] ...

    Abstract In the original publication [.]
    Keywords n/a ; Medicine ; R
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Depression Is Associated with an Increased Risk of Subsequent Cancer Diagnosis: A Retrospective Cohort Study with 235,404 Patients.

    Mössinger, Hannah / Kostev, Karel

    Brain sciences

    2023  Volume 13, Issue 2

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-02-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2651993-8
    ISSN 2076-3425
    ISSN 2076-3425
    DOI 10.3390/brainsci13020302
    Database MEDical Literature Analysis and Retrieval System OnLINE

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