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  1. Article: KEYNOTE-024: goodbye to chemotherapy?

    Berardi, Rossana

    Journal of thoracic disease

    2019  Volume 11, Issue Suppl 3, Page(s) S428–S432

    Language English
    Publishing date 2019-04-09
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd.2018.11.65
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Corrigendum: Aromatase inhibitors: the journey from the state of the art to clinical open questions.

    Generali, Daniele / Berardi, Rossana / Caruso, Michele / Cazzaniga, Marina / Garrone, Ornella / Minchella, Ida / Paris, Ida / Pinto, Carmine / De Placido, Sabino

    Frontiers in oncology

    2024  Volume 14, Page(s) 1369562

    Abstract: This corrects the article DOI: 10.3389/fonc.2023.1249160.]. ...

    Abstract [This corrects the article DOI: 10.3389/fonc.2023.1249160.].
    Language English
    Publishing date 2024-01-23
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2024.1369562
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Potential dual synergy between electrochemotherapy and sequence of immunotherapies in metastatic melanoma: A case report.

    Morgese, Francesca / De Feudis, Francesco / Balercia, Paolo / Berardi, Rossana

    Molecular and clinical oncology

    2023  Volume 18, Issue 2, Page(s) 8

    Abstract: Immune checkpoint inhibitors have changed the natural history of advanced melanoma. Despite this, a notable proportion of patients immediately relapse or develop resistance during immunotherapy, especially with the appearance of superficial metastases ... ...

    Abstract Immune checkpoint inhibitors have changed the natural history of advanced melanoma. Despite this, a notable proportion of patients immediately relapse or develop resistance during immunotherapy, especially with the appearance of superficial metastases and consequently with a dramatic impact on clinical outcomes. Local treatment by electrochemotherapy (ECT), parallel to regional control with palliative aim, seems to release neoantigens potentially determining a significant systemic anticancer immune reactivation. The present study reported a case of a patient with metastatic melanoma receiving Pembrolizumab, electrochemotherapy and then Ipilimumab for in-transit and finally locoregional lymph nodes and distant bone metastases with experience of clinic-radiological remission. Specifically, the present patient progressed during adjuvant treatment with in-transit metastases on the scalp; he underwent two cycle of ECT obtaining partial and then unexpected and very fast nearly complete response with the Ipilimumab treatment. Concomitantly, he developed grade 4 endocrine adverse events (hypophysitis and diabetes mellitus type I) as immune-related toxicities. At 12 months from ECT the patient is in ECOG Performance Status 0 and he has resumed a regular social life. In our experience, ECT in two administrations increased and accelerated the response of Ipilimumab. The present confirmed its promising contribution in inducing a powerful immune response in order to overcome primary or acquired resistance to immune checkpoint inhibitors such as anti-programmed death antigen-1 drugs.
    Language English
    Publishing date 2023-01-10
    Publishing country England
    Document type Case Reports
    ZDB-ID 2796865-0
    ISSN 2049-9469 ; 2049-9450
    ISSN (online) 2049-9469
    ISSN 2049-9450
    DOI 10.3892/mco.2023.2604
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Using temperament and character dimensions (TCI) to analyze the personality profiles of adults and older adults with cancer managed in outpatient settings.

    Vespa, Anna / Giulietti, Maria Velia / Fabbietti, Paolo / Di Rosa, Mirko / Gattafoni, Pisana / Berardi, Rossana / Arnaldi, Giorgio / Balercia, Giancarlo / Spatuzzi, Roberta

    Frontiers in psychology

    2024  Volume 14, Page(s) 1289093

    Abstract: Introduction: This study aimed to investigate profiles of personality evaluated by temperament and character dimensions (TCI) in 638 adult and older adult patients (CP) who had recently been diagnosed with breast, colon, lung, and other kinds of cancer ( ...

    Abstract Introduction: This study aimed to investigate profiles of personality evaluated by temperament and character dimensions (TCI) in 638 adult and older adult patients (CP) who had recently been diagnosed with breast, colon, lung, and other kinds of cancer (female and male subjects were assessed). Tests: Temperament and Character Inventory (TCI). Statistical analysis: cluster K-means analysis for personality traits.
    Results: Two different personality profiles emerged: "Low self-determination and pessimism" (Profile 1) and "Self-determination and self-caring (medium)" (Profile 2). The following significant differences were observed in the TCI dimensions between the two profiles: Temperament-Novelty-Seeking (NS) (
    Conclusion: Personality screening allows a better understanding of the difficulties of the individual patient and the planning of targeted psychotherapeutic interventions that promote quality of life and good adaptation to the disease course.
    Language English
    Publishing date 2024-01-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2023.1289093
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Potential benefit of β-glucans as adjuvant therapy in immuno-oncology: a review.

    Cognigni, Valeria / Ranallo, Nicoletta / Tronconi, Francesca / Morgese, Francesca / Berardi, Rossana

    Exploration of targeted anti-tumor therapy

    2021  Volume 2, Issue 2, Page(s) 122–138

    Abstract: Fungal compounds have long been used for centuries as food supplements. β-glucans have been identified as the most interesting molecules with beneficial effects in several chronic diseases. ...

    Abstract Fungal compounds have long been used for centuries as food supplements. β-glucans have been identified as the most interesting molecules with beneficial effects in several chronic diseases.
    Language English
    Publishing date 2021-04-30
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2692-3114
    ISSN (online) 2692-3114
    DOI 10.37349/etat.2021.00036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Lung cancer prognosis: can histological patterns and morphological features have a role in the management of lung cancer patients?

    Rinaldi, Silvia / Berardi, Rossana

    Annals of translational medicine

    2017  Volume 5, Issue 17, Page(s) 353

    Language English
    Publishing date 2017-09-07
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2893931-1
    ISSN 2305-5847 ; 2305-5839
    ISSN (online) 2305-5847
    ISSN 2305-5839
    DOI 10.21037/atm.2017.05.18
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Yes-associated protein and immunosuppressive microenvironment in pancreatic cancer development: a new strategy to improve immunotherapy efficacy?

    Berardi, Rossana / Bittoni, Alessandro

    Journal of thoracic disease

    2017  Volume 9, Issue 7, Page(s) 1798–1801

    Language English
    Publishing date 2017-08-18
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd.2017.06.60
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: The role of an immune checkpoint score in resected non-small cell lung cancer patients' prognosis.

    Berardi, Rossana / Rinaldi, Silvia

    Journal of thoracic disease

    2017  Volume 9, Issue 10, Page(s) 3480–3482

    Language English
    Publishing date 2017-12-18
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd.2017.09.130
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Non-small-cell lung cancer: how to manage

    Pecci, Federica / Cantini, Luca / Metro, Giulio / Ricciuti, Biagio / Lamberti, Giuseppe / Farooqi, Ammad Ahmad / Berardi, Rossana

    Drugs in context

    2022  Volume 11

    Abstract: The treatment of non-small-cell lung cancer (NSCLC) ... ...

    Abstract The treatment of non-small-cell lung cancer (NSCLC) harbouring
    Language English
    Publishing date 2022-08-03
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2719560-0
    ISSN 1740-4398 ; 1745-1981
    ISSN (online) 1740-4398
    ISSN 1745-1981
    DOI 10.7573/dic.2022-4-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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  10. Article: Current Evidence and Future Perspectives about the Role of PARP Inhibitors in the Treatment of Thoracic Cancers.

    Parisi, Alessandro / Rossi, Francesca / De Filippis, Chiara / Paoloni, Francesco / Felicetti, Cristiano / Mammarella, Alex / Pecci, Federica / Lupi, Alessio / Berardi, Rossana

    OncoTargets and therapy

    2023  Volume 16, Page(s) 585–613

    Abstract: In recent years, poly (ADP-ribose) polymerase (PARP) inhibition has become a promising therapeutic option for several tumors, especially for those harboring a BRCA 1-2 mutation or a deficit in the homologous recombination repair (HRR) pathway. ... ...

    Abstract In recent years, poly (ADP-ribose) polymerase (PARP) inhibition has become a promising therapeutic option for several tumors, especially for those harboring a BRCA 1-2 mutation or a deficit in the homologous recombination repair (HRR) pathway. Nevertheless, to date, PARP inhibitors are still not largely used for thoracic malignancies neither as a single agent nor in combination with other treatments. Recently, a deeper understanding of HRR mechanisms, alongside the development of new targeted and immunotherapy agents, particularly against HRR-deficient tumors, traced the path to new treatment strategies for many tumor types including lung cancer and malignant pleural mesothelioma. The aim of this review is to sum up the current knowledge about cancer-DNA damage response pathways inhibition and to update the status of recent clinical trials investigating the use of PARP inhibitors, either as monotherapy or in combination with other agents for the treatment of thoracic malignancies. We will also briefly discuss available evidence on Poly(ADP-Ribose) Glycohydrolase (PARG) inhibitors, a novel promising therapeutic option in oncology.
    Language English
    Publishing date 2023-07-18
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2495130-4
    ISSN 1178-6930
    ISSN 1178-6930
    DOI 10.2147/OTT.S272563
    Database MEDical Literature Analysis and Retrieval System OnLINE

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