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  1. Article ; Online: Parosmia in patients with COVID-19 and olfactory dysfunction.

    Raad, Nasim / Ghorbani, Jahangir / Safavi Naeini, Ali / Tajik, Neda / Karimi-Galougahi, Mahboobeh

    International forum of allergy & rhinology

    2021  Volume 11, Issue 10, Page(s) 1497–1500

    MeSH term(s) COVID-19 ; Humans ; Olfaction Disorders ; SARS-CoV-2 ; Smell
    Language English
    Publishing date 2021-06-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2625826-2
    ISSN 2042-6984 ; 2042-6976
    ISSN (online) 2042-6984
    ISSN 2042-6976
    DOI 10.1002/alr.22818
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  2. Article ; Online: Sub-terahertz silicon-based on-chip absorption spectroscopy using thin-film model for biological applications.

    Hosseini Farahabadi, Seyed Ali / Entezami, Milad / Abouali, Hesam / Amarloo, Hadi / Poudineh, Mahla / Safavi-Naeini, Safieddin

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 17747

    Abstract: Spectroscopy in the sub-terahertz (sub-THz) range of frequencies has been utilized to study the picosecond dynamics and interaction of biomolecules. However, widely used free-space THz spectrometers are typically limited in their functionality due to low ...

    Abstract Spectroscopy in the sub-terahertz (sub-THz) range of frequencies has been utilized to study the picosecond dynamics and interaction of biomolecules. However, widely used free-space THz spectrometers are typically limited in their functionality due to low signal-to-noise ratio and complex setup. On-chip spectrometers can revolutionize THz spectroscopy allowing integration, compactness, and low-cost fabrication. In this paper, a low-loss silicon-based platform is proposed for on-chip sub-THz spectroscopy. Through functionalization of silicon chip and immobilization of bio-particles, we demonstrate the ability to characterize low-loss nano-scale biomolecules across the G-band (0.14-0.22 THz). We also introduce an electromagnetic thin-film model to account for the loading effect of the immobilized biomolecules, i.e. dehydrated streptavidin and immunoglobulin antibody, as two key molecules in the biosensing discipline. The proposed platform was fabricated using a single mask micro-fabrication process, and then measured by a vector network analyzer (VNA), which offers high dynamic range and high spectral resolution measurements. The proposed planar platform is general and paves the way towards low-loss, cost-effective and integrated sub-THz biosensors for the detection and characterization of biomolecules.
    MeSH term(s) Silicon ; Streptavidin ; Terahertz Spectroscopy/methods
    Chemical Substances Silicon (Z4152N8IUI) ; Streptavidin (9013-20-1)
    Language English
    Publishing date 2022-10-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-21015-8
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  3. Article: Structural Characteristics of the Iranians Nose: An Anatomical Analysis.

    Ghorbani, Jahangir / Safavi Naeini, Ali / Mehrparvar, Golfam / Doroudinia, Atsa / Kahkouee, Shahram / Emami, Habib

    Iranian journal of otorhinolaryngology

    2020  Volume 32, Issue 112, Page(s) 295–301

    Abstract: Introduction: Rhinoplasty is one of the most common surgical procedures performed among Iranians. An important issue to be considered by nasal surgeons is anatomical variations between different ethnic groups. Working on Iranians with the existing ... ...

    Abstract Introduction: Rhinoplasty is one of the most common surgical procedures performed among Iranians. An important issue to be considered by nasal surgeons is anatomical variations between different ethnic groups. Working on Iranians with the existing ethnic variety encourages the need for an analysis of this particular population.
    Materials and methods: The present cross-sectional observational study was conducted on Iranian patients who underwent primary open rhinoplasty at a university hospital in Tehran, Iran. The preoperative evaluations included routine aesthetic analysis as well as the measurement of the subcutaneous fat thickness (using ultrasound imaging) and the angle between the anterior nasal spine and the alveolar process of the maxilla. Intraoperative assessments were performed on the alar rim-inferior border of lateral crus distance, maximal width of lateral crus, connection pattern of upper lateral cartilage, and lower lateral cartilage. Alar cartilage thickness was measured with microscopic evaluation. Moreover, the similar studies conducted on other ethnic groups were reviewed as well.
    Results: In total, 66 cases were included in the study (41 females and 25 males) who were within the age range of 18-38 years old (27.82±5.51). According to the results, nasolabial angles were 93.68°±7.82° and 92.25°±6.98° in females and males, respectively. In addition, a significant correlation was found between the anterior nasal spine-maxilla angle and nasolabial angle (P<0.05). Moreover, the findings revealed a significant but weak negative correlation between alar subcutaneous fat thickness and alar cartilage thickness (0.0002). Maximal width of lateral crus was found to be 11.44mm±2.02 and 10.41 mm±1.72 in males and females, respectively.
    Conclusion: Despite the differences observed between various ethnic groups, drawing a definiteconclusion about these variations needs comparative studies with similar samples (cadaver vs. patients) and measurement techniques.
    Language English
    Publishing date 2020-09-29
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 3018470-8
    ISSN 2251-726X ; 2251-7251
    ISSN (online) 2251-726X
    ISSN 2251-7251
    DOI 10.22038/ijorl.2020.42574.2391
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  4. Article ; Online: Can be compared obstructive respiratory events during drug induced sleep endoscopy (DISE) and nocturnal polysomnography.

    Ghorbani, Jahangir / Adimi Naghan, Parisa / Safavi Naeini, Ali / Sadeghi Haghighi, Kosar

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2020  Volume 277, Issue 5, Page(s) 1379–1384

    Abstract: Purpose: Obstructive sleep apnea (OSA) is a collapse of pharynx muscles during sleep that can cause obstruction in the upper airway. It is better to determine the site and pattern of obstruction in the upper airway with drug-induced sleep endoscopy ( ... ...

    Abstract Purpose: Obstructive sleep apnea (OSA) is a collapse of pharynx muscles during sleep that can cause obstruction in the upper airway. It is better to determine the site and pattern of obstruction in the upper airway with drug-induced sleep endoscopy (DISE) before surgery. OSA usually occurs in a non-rapid eye movement (NREM) sleep and sometimes it gets longer and more intense in REM; hence, the study is meant to explore whether the sleep stage and results in DISE may have any similarity with usual nocturnal polysomnography or not.
    Materials and methods: In this study, 38 patients with OSA diagnosed on the basis of polysomnography, underwent DISE. Moreover, EEG (12 channels), pulse oximetry and effort channel (respiratory inductance plethysmography) were recorded during DISE to determine the sleep stage and mean respiratory event duration (MRED).
    Results: Thirty-eight patients were enrolled in this study. Eighty-four percent (84%) of obstructive respiratory events were observed in NREM sleep in Lab-PSG and 71% in DISE. 28.9% of patients' events occurred in the wake state in DISE. The mean respiratory event duration (MRED) values in DISE and nighttime sleep were 24.5 ± 7.5 s and 25.4 ± 7.7 s, respectively without significant difference (P value = 0.744), while the minimum values for SPO
    Conclusions: Considering the fact that the majority of respiratory events occurred in NREM sleep stage in both PSG and DISE, DISE results can be trusted. Due to absence of REM stage in DISE, the level of the obstruction may mislead the surgeon.
    MeSH term(s) Endoscopy ; Humans ; Pharmaceutical Preparations ; Polysomnography ; Sleep ; Sleep Apnea, Obstructive/diagnosis
    Chemical Substances Pharmaceutical Preparations
    Language English
    Publishing date 2020-02-21
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-020-05848-5
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    Ul II Zs.50: Show issues Location:
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  5. Article ; Online: Case Report: COVID-19-associated Rhinosinusitis Mucormycosis Caused by Rhizopus arrhizus: A Rare but Potentially Fatal Infection Occurring After Treatment with Corticosteroids.

    Tabarsi, Payam / Khalili, Neda / Pourabdollah, Mihan / Sharifynia, Somayeh / Safavi Naeini, Ali / Ghorbani, Jahangir / Mohamadnia, Abdolreza / Abtahian, Zahra / Askari, Elham

    The American journal of tropical medicine and hygiene

    2021  Volume 105, Issue 2, Page(s) 449–453

    Abstract: COVID-19 first emerged in Wuhan, China, in December 2019. Since that time, the frequency of bacterial and fungal coinfections has been continuously increasing. Although invasive pulmonary aspergillosis is being increasingly recognized in association with ...

    Abstract COVID-19 first emerged in Wuhan, China, in December 2019. Since that time, the frequency of bacterial and fungal coinfections has been continuously increasing. Although invasive pulmonary aspergillosis is being increasingly recognized in association with COVID-19, there is limited information regarding COVID-19-associated mucormycosis. We describe a 50-year-old woman with uncontrolled diabetes who received systemic corticosteroids and remdesevir during her admission for COVID-19. A few days after discharge, the patient was readmitted because of facial swelling and numbness, and a diagnosis of COVID-19-associated rhinosinusitis mucormycosis caused by Rhizopus arrhizus (formerly called Rhizopus oryzae) was confirmed with sequencing of the internal transcribed spacer region of the ribosomal DNA. This report aimed to address the importance of short-term follow-up for COVID-19 patients who have received systemic corticosteroids, particularly those with predisposing conditions, because early detection and prompt, aggressive treatment are essential for the management of invasive fungal infections.
    MeSH term(s) Adrenal Cortex Hormones/administration & dosage ; Adrenal Cortex Hormones/adverse effects ; Adrenal Cortex Hormones/therapeutic use ; COVID-19/complications ; COVID-19/drug therapy ; DNA, Fungal/genetics ; DNA, Ribosomal Spacer/genetics ; Diabetes Mellitus ; Fatal Outcome ; Female ; Humans ; Invasive Fungal Infections/etiology ; Middle Aged ; Mucormycosis ; Rhinitis/diagnosis ; Rhinitis/etiology ; Rhinitis/microbiology ; Rhizopus oryzae/pathogenicity ; SARS-CoV-2/drug effects ; Sinusitis/diagnosis ; Sinusitis/etiology ; Sinusitis/microbiology
    Chemical Substances Adrenal Cortex Hormones ; DNA, Fungal ; DNA, Ribosomal Spacer
    Language English
    Publishing date 2021-07-08
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2942-7
    ISSN 1476-1645 ; 0002-9637
    ISSN (online) 1476-1645
    ISSN 0002-9637
    DOI 10.4269/ajtmh.21-0359
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  6. Article ; Online: Vertigo and hearing loss during the COVID-19 pandemic - is there an association?

    Karimi-Galougahi, Mahboobeh / Naeini, Ali Safavi / Raad, Nasim / Mikaniki, Narges / Ghorbani, Jahangir

    Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale

    2020  Volume 40, Issue 6, Page(s) 463–465

    MeSH term(s) Adult ; COVID-19/complications ; COVID-19/pathology ; Female ; Hearing Loss/etiology ; Hearing Loss/virology ; Humans ; Male ; SARS-CoV-2 ; Vertigo/etiology ; Vertigo/virology ; Young Adult
    Keywords covid19
    Language English
    Publishing date 2020-06-10
    Publishing country Italy
    Document type Letter
    ZDB-ID 604898-5
    ISSN 1827-675X ; 0392-100X
    ISSN (online) 1827-675X
    ISSN 0392-100X
    DOI 10.14639/0392-100X-N0820
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  7. Article ; Online: Olfactory Bulb Magnetic Resonance Imaging in SARS-CoV-2-Induced Anosmia: The First Report.

    Galougahi, Mahboobeh Karimi / Ghorbani, Jahangir / Bakhshayeshkaram, Mehrdad / Naeini, Ali Safavi / Haseli, Sara

    Academic radiology

    2020  Volume 27, Issue 6, Page(s) 892–893

    MeSH term(s) Adult ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Humans ; Magnetic Resonance Imaging ; Male ; Olfaction Disorders/diagnostic imaging ; Olfaction Disorders/etiology ; Olfactory Bulb/diagnostic imaging ; Pandemics ; Pneumonia, Viral/complications ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-04-11
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 1355509-1
    ISSN 1878-4046 ; 1076-6332
    ISSN (online) 1878-4046
    ISSN 1076-6332
    DOI 10.1016/j.acra.2020.04.002
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  8. Article ; Online: Short-Term Effect of Gabapentin on Subjective Tinnitus in Acoustic Trauma Patients

    Ali Goljanian Tabrizi / Abbas Safavi Naeini / Nima Baradaran

    Iranian Journal of Otorhinolaryngology, Vol 29, Iss 2, Pp 95-

    2017  Volume 100

    Abstract: Introduction:Although several treatment approaches have been proposed for tinnitus, there are currently no Food and Drug Administration (FDA)-approved agents available to treat this condition. In this study, we evaluated the effect of gabapentin on the ... ...

    Abstract Introduction:Although several treatment approaches have been proposed for tinnitus, there are currently no Food and Drug Administration (FDA)-approved agents available to treat this condition. In this study, we evaluated the effect of gabapentin on the sensation of subjective tinnitus in patients with acoustic trauma referring to the ear, nose and throat (ENT) clinic of Taleghani Hospital during 2014. Materials and Methods:In this double-blind, randomized clinical trial, 103 patients with tinnitus due to acoustic trauma who were referred to the ENT clinic of Taleghani Hospital during 2014 were randomized to the gabapentin (300 mg bid, n=55) or control (n=48) groups. The two groups were then compared before and after 6 weeks of treatment using a visual analog scale (VAS). At least a 30% reduction in VAS was considered a response to treatment. Results:Differences between the two groups regarding sex, age, duration of disease, and audiometry results was not significant (P>0.05). After 6 weeks’ treatment, the VAS significantly decreased in both groups (P
    Keywords Acoustic trauma ; Gabapentin ; Subjective tinnitus ; Otorhinolaryngology ; RF1-547 ; Medicine ; R
    Subject code 150
    Language English
    Publishing date 2017-03-01T00:00:00Z
    Publisher Mashhad University of Medical Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Olfactory Bulb Magnetic Resonance Imaging in SARS-CoV-2-Induced Anosmia: The First Report

    Galougahi, Mahboobeh Karimi / Ghorbani, Jahangir / Bakhshayeshkaram, Mehrdad / Naeini, Ali Safavi / Haseli, Sara

    Acad Radiol

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #47358
    Database COVID19

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  10. Article: Vertigo and hearing loss during the COVID-19 pandemic - is there an association?

    Karimi-Galougahi, Mahboobeh / Naeini, Ali Safavi / Raad, Nasim / Mikaniki, Narges / Ghorbani, Jahangir

    Acta otorhinolaryngol. ital

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #594751
    Database COVID19

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