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Article ; Online: Public Engagement as the Fifth Dimension of Outbreak Communication: Public's Perceptions of Public Health Communication during COVID-19 in India.

Venkatraman, Krithika / Manoharan, Anand

2021 Volume 38, Issue 2, Page(s) 285–297

Abstract: Public health/risk communication is the foremost responsibility of a government during a pandemic. Risk communication aims to educate people, enhance their risk perceptions to help them engage and understand the benefits of compliance with ... ...

Abstract	Public health/risk communication is the foremost responsibility of a government during a pandemic. Risk communication aims to educate people, enhance their risk perceptions to help them engage and understand the benefits of compliance with recommendations. The existing legal enforcement of recommendations in India is criticized for failing to influence the public's compliance. While existing research provides conceptual and empirical support in explaining compliance during COVID-19, we note a lack of studies that might bring out country-specific areas of improvement. We argue that value-aligned risk communication is more likely to influence the public's behavioral intentions to adopt the government's recommendations. We employed a triangulation mixed-method study to link risk communication attributes to the public's end goals and values. We triangulate these findings using the COVID score survey. We found that timeliness and transparency constitute risk communication's functional component, and empathy and trust constitute risk communication's emotional component. We found a difference in the preference of functional and emotional components among the public and health partners. Irrespective of this divide in perception, the study found that both groups unanimously noted engagement as the crucial aspect for empowerment and involvement to aid the public in teaming with the government to combat the pandemic effectively.
MeSH term(s)	Humans ; COVID-19/epidemiology ; Health Communication ; Public Health ; Communication ; Disease Outbreaks/prevention & control ; India/epidemiology
Language	English
Publishing date	2021-07-22
Publishing country	England
Document type	Journal Article
ZDB-ID	1038723-7
ISSN	1532-7027 ; 1041-0236
ISSN (online)	1532-7027
ISSN	1041-0236
DOI	10.1080/10410236.2021.1950294
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Article: Paediatric Renal Synovial Sarcoma: Another Diagnostic Pathological Dilemma.

Kanuj, Malik / Anand, Raja / Venkatraman, Radhakrishnan / Mayank, Gupta

Indian journal of surgical oncology

2019 Volume 11, Issue 1, Page(s) 138–141

Language	English
Publishing date	2019-10-27
Publishing country	India
Document type	Case Reports
ZDB-ID	2568289-1
ISSN	0976-6952 ; 0975-7651
ISSN (online)	0976-6952
ISSN	0975-7651
DOI	10.1007/s13193-019-00989-4
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Article: Comparison of morphine, dexmedetomidine and dexamethasone as an adjuvant to ropivacaine in ultrasound-guided supraclavicular brachial plexus block for postoperative analgesia-a randomized controlled trial.

Venkatraman, Rajagopalan / Pushparani, Anand / Karthik, Krishnamoorthy / Nandhini, Prabuvel

Journal of anaesthesiology, clinical pharmacology

2021 Volume 37, Issue 1, Page(s) 102–107

Abstract: Background and aims: An ideal adjuvant to local anesthetic in a nerve block should prolong the duration of analgesia, and hasten the onset of sensory and motor blockade without significant adverse effects. The aim of this study was to compare morphine, ... ...

Abstract	Background and aims: An ideal adjuvant to local anesthetic in a nerve block should prolong the duration of analgesia, and hasten the onset of sensory and motor blockade without significant adverse effects. The aim of this study was to compare morphine, dexmedetomidine, and dexamethasone as an additive to ropivacaine in ultrasound-guided supraclavicular brachial plexus block (SBPB) for postoperative analgesia. Material and methods: In this randomized, double-blinded study, 150 patients undergoing upper extremity surgery were randomly divided into three groups: group A (morphine 5 mg), group B (dexmedetomidine 50 μg), and group C (dexamethasone 8 mg). The additives were added to 30 ml of 0.5% ropivacaine solution and administered in SBPB. The duration of postoperative analgesia, onset of sensory and motor blockade, sedation, and adverse effects were observed. The pain was assessed by visual analog scale (VAS) and sedation by Ramsay sedation score. The duration of postoperative analgesia was taken as time consumed from block completion to administration of rescue analgesia (VAS >3). Results: The demographic profile was similar in both groups. The duration of analgesia was significantly longer in dexamethasone (867.2 ± 217.6 min) than morphine (739. 2 ± 162.5 min) and dexmedetomidine (654.2 ± 179.9 min) ( Conclusion: Dexamethasone is an ideal adjuvant to ropivacaine in brachial plexus block to prolong postoperative analgesia and devoid of adverse effects. Dexmedetomidine has a quicker onset of sensory and motor blockade.
Language	English
Publishing date	2021-04-10
Publishing country	India
Document type	Journal Article
ZDB-ID	1401760-x
ISSN	0970-9185
ISSN	0970-9185
DOI	10.4103/joacp.JOACP_70_19
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Zs.A 4830: Show issues

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Article ; Online: Designing Dynamic Interventions to Improve Adherence in Pediatric Long-Term Treatment - The Role of Perceived Value of the Physician by Primary Caregivers.

Venkatraman, Krithika / Vijayalakshmi, V / Sudarsanam, Nandan / Manoharan, Anand

Health communication

2020 Volume 36, Issue 14, Page(s) 1825–1840

Abstract: Primary Caregivers are the fulcrum in the physician-caregiver-child triad. Existing literature discusses static multi-component interventions in detail. In long-term treatments, dynamic intervention design is needed as the environment and situations of ... ...

Abstract	Primary Caregivers are the fulcrum in the physician-caregiver-child triad. Existing literature discusses static multi-component interventions in detail. In long-term treatments, dynamic intervention design is needed as the environment and situations of the families are dynamic. The objectives of this study are (a) to identify the components of the primary caregiver's perception of the physician's value with reference to the effectiveness of consultation and relationships with the former and with the child; (b) to establish the role of this perception in designing dynamic interventions, and (c) to describe the perception's potential influence on adherence. A PRISMA, chronological, and morphological analysis of the literature is carried out about caregivers' adherence in the pediatric long-term treatment context. We define communication and consultation as the functional, whereas relationship as the emotional component of the caregiver's perception of the physician. We propose a theoretical model that incorporates intervention as an integral component of care. Adherence happens as a response to changing situations and hence fluctuates. Hence, a dynamic intervention design to benefit the child should be incorporated into care through the caregiver-physician bridge. Future research should explore how intervention needs change and the driving reasons for understanding the static and dynamic components of interventions.
MeSH term(s)	Caregivers ; Communication ; Family ; Humans ; Physicians
Language	English
Publishing date	2020-07-31
Publishing country	England
Document type	Journal Article
ZDB-ID	1038723-7
ISSN	1532-7027 ; 1041-0236
ISSN (online)	1532-7027
ISSN	1041-0236
DOI	10.1080/10410236.2020.1796284
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Article ; Online: Eficácia de diferentes doses e esquemas de administração de ácido tranexâmico em cirurgias ortopédicas de grande porte: estudo randomizado.

Saravanan, Ravi / Venkatraman, Rajagopalan / Karthik, Krishnamoorthy / Pushparani, Anand

Brazilian journal of anesthesiology (Elsevier)

2020 Volume 70, Issue 4, Page(s) 311–317

Abstract: Background: Tranexamic acid was studied in four different dosage regimens and their efficacy was compared for perioperative blood loss reduction, blood transfusion requirements and deep vein thrombosis (DVT) complication.: Methods: Two hundred ... ...

Title translation	Efficacy of different doses and timing of tranexamic acid in major orthopedic surgeries: a randomized trial.
Abstract	Background: Tranexamic acid was studied in four different dosage regimens and their efficacy was compared for perioperative blood loss reduction, blood transfusion requirements and deep vein thrombosis (DVT) complication. Methods: Two hundred patients undergoing major orthopedic procedures were divided into five groups containing 40 each: placebo, low dose (bolus 10mg.kg Results: The intraoperative blood loss was 440±207.54mL in the placebo group, 412.5±208.21mL in the low dose group, 290±149.6ml in the low dose plus maintenance group, 332.5±162.33mL in the high dose group and 240.7±88.15mL in the high dose maintenance group (p <0.001). The reduction in postoperative blood loss in the drain for the first 24hours was 80±44.44mL in the placebo group, 89.88±44.87mL in the low dose group, 56.7±29.12mL in the low dose plus maintenance group, 77.9±35.74mL in the high dose group and 46.7±19.9mL in the high dose maintenance group (p <0.001). DVT was not encountered in any patient. Conclusion: Tranexamic acid was most effective in reducing surgical blood loss and blood transfusion requirements in a low dose+maintenance group.
MeSH term(s)	Adult ; Aged ; Antifibrinolytic Agents/administration & dosage ; Blood Loss, Surgical/prevention & control ; Blood Transfusion/statistics & numerical data ; Dose-Response Relationship, Drug ; Double-Blind Method ; Drug Administration Schedule ; Female ; Humans ; Male ; Middle Aged ; Orthopedic Procedures/methods ; Postoperative Hemorrhage/prevention & control ; Prospective Studies ; Tranexamic Acid/administration & dosage
Chemical Substances	Antifibrinolytic Agents ; Tranexamic Acid (6T84R30KC1)
Language	Portuguese
Publishing date	2020-07-08
Publishing country	Brazil
Document type	Comparative Study ; Journal Article ; Randomized Controlled Trial
ISSN	2352-2291
ISSN (online)	2352-2291
DOI	10.1016/j.bjan.2020.03.013
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Article ; Online: Comparison of low dose intravenous fentanyl and morphine infusion for postoperative analgesia in spine fusion surgeries - a randomized control trial.

Venkatraman, Rajagopalan / Pushparani, Anand / Balaji, Ramamurthy / Nandhini, Prabhuvel

Brazilian journal of anesthesiology (Elsevier)

2020 Volume 71, Issue 4, Page(s) 339–344

Abstract: Background and aims: Post-operative analgesia for Spine surgeries is difficult without patient control analgesia (PCA) and inadequate monitoring facilities. The objective was to study the effectiveness of analgesia of intravenous administration of low ... ...

Abstract	Background and aims: Post-operative analgesia for Spine surgeries is difficult without patient control analgesia (PCA) and inadequate monitoring facilities. The objective was to study the effectiveness of analgesia of intravenous administration of low dose fentanyl and morphine for postoperative analgesia following spine fusion surgeries. Methods: One hundred adult patients undergoing spine instrumentation surgeries were randomly allotted into two groups: Group M (morphine) or Group F (fentanyl). The patients received either 0.02 mg.kg Results: The demographic characteristics did not reveal significant difference among the two groups. In morphine group, 32 patients did not require any additional bolus dose, 15 patients needed one bolus dose and one patient each required two and three boluses. In fentanyl group, two, 24, 20 and four patients required 0, 1, 2 and 3 bolus doses respectively. There were no statistically significant variations in hemodynamic features like heart rate, blood pressure and oxygen saturation, RSS and VAS. The complication rate was not significant among the groups. Conclusion: Low dose continuous infusion of morphine is more effective than fentanyl with fewer requirements of rescue analgesics for postoperative analgesia. Both drugs are safe without any serious complications.
MeSH term(s)	Adult ; Analgesia, Patient-Controlled ; Analgesics, Opioid/therapeutic use ; Fentanyl ; Humans ; Infusions, Intravenous ; Morphine ; Pain Measurement ; Pain, Postoperative/drug therapy ; Pain, Postoperative/prevention & control
Chemical Substances	Analgesics, Opioid ; Morphine (76I7G6D29C) ; Fentanyl (UF599785JZ)
Language	English
Publishing date	2020-12-28
Publishing country	Brazil
Document type	Journal Article ; Randomized Controlled Trial
ISSN	2352-2291
ISSN (online)	2352-2291
DOI	10.1016/j.bjane.2020.12.013
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Article: Comparison of laparoscopy-guided with ultrasound-guided subcostal transversus abdominis plane block in laparoscopic cholecystectomy - A prospective, randomised study.

Venkatraman, Rajagopalan / Saravanan, Ravi / Dhas, Meshach / Pushparani, Anand

Indian journal of anaesthesia

2020 Volume 64, Issue 12, Page(s) 1012–1017

Abstract: Background and aims: Subcostal transversus abdominis plane (TAP) block is usually done under ultrasound guidance in laparoscopic cholecystectomy. Laparoscopic-guided subcostal TAP block is an alternate technique where ultrasound is not available. Our ... ...

Abstract	Background and aims: Subcostal transversus abdominis plane (TAP) block is usually done under ultrasound guidance in laparoscopic cholecystectomy. Laparoscopic-guided subcostal TAP block is an alternate technique where ultrasound is not available. Our primary objective was to compare the success rate of ultrasound and laparoscopic approaches to the subcostal TAP block. The secondary objectives were to assess the duration of postoperative analgesia and morphine consumption postoperatively for 24 h. Methods: Eighty patients undergoing laparoscopic cholecystectomy were randomly divided into two groups with patients receiving ultrasound-guided (group U) or laparoscopy-guided (group L) subcostal TAP block at the end of surgery. The success rate was assessed by a sensory blockade of T7 and T8 dermatomes 30 min after extubation. The duration of analgesia was taken as time from block administration to the visual analogue scale of ≥3. Morphine was administered in patient-controlled analgesia (PCA) pump with a bolus of 1 mg and a lock-out interval of 10 min. The total morphine consumption was recorded. The statistical analysis was performed with student Results: The success rate of group U (100%) was higher than group L (88%) but it was not statistically significant ( Conclusion: Laparoscopy-guided subcostal TAP block is a suitable alternative to ultrasound-guided block and can be utilised in places where an ultrasound machine is not available.
Language	English
Publishing date	2020-12-12
Publishing country	India
Document type	Journal Article
ZDB-ID	412570-8
ISSN	0019-5049
ISSN	0019-5049
DOI	10.4103/ija.IJA_528_20
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Article: Nerve-Sparing Postchemotherapy Retroperitoneal Lymph Node Dissection (PC RPLND) for Nonseminomatous Germ Cell Tumour: Experience from a Tertiary Cancer Centre.

Raja, Anand / Malik, Kanuj / Kathiresan, N / Radhakrishnan, Venkatraman

Indian journal of surgical oncology

2021 Volume 12, Issue 2, Page(s) 374–377

Abstract: Postchemotherapy RPLND remains an integral part of management of testicular tumours. Nerve-sparing techniques can minimize the ejaculatory dysfunction due to the procedure. We report our functional and oncological outcomes for nerve-sparing RPLND in ... ...

Abstract	Postchemotherapy RPLND remains an integral part of management of testicular tumours. Nerve-sparing techniques can minimize the ejaculatory dysfunction due to the procedure. We report our functional and oncological outcomes for nerve-sparing RPLND in postchemotherapy settings. We analysed data from all patients undergoing nerve-sparing PC RPLND from January 1990 to December 2013 at our institute. Antegrade ejaculation and fertility issues were determined by patient history. Nerve sparing was achieved in 30% of patients undergoing PC RPLND. Of the 33 patients who underwent nerve-sparing PC RPLND, 19 (57.8%) had antegrade ejaculation. The mean time to antegrade ejaculation was 6.8 months. After a median follow-up of 75.61 months, 5-year disease-free survival was 98%. Nerve-sparing RPLND can improve functional outcomes without increasing recurrence rates in post chemotherapy setting.
Language	English
Publishing date	2021-03-25
Publishing country	India
Document type	Journal Article
ZDB-ID	2568289-1
ISSN	0976-6952 ; 0975-7651
ISSN (online)	0976-6952
ISSN	0975-7651
DOI	10.1007/s13193-021-01313-9
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Article ; Online: Can natural irrigants replace sodium hypochlorite? A systematic review.

Susila, Anand Venkatraman / Sai, Shamini / Sharma, Nikita / Balasubramaniam, Arthi / Veronica, Aruna Kumari / Nivedhitha, Sureshbabu

Clinical oral investigations

2023 Volume 27, Issue 5, Page(s) 1831–1849

Abstract: Context: Sodium hypochlorite, a gold standard for irrigation in endodontics, has disadvantages like toxicity and root dentin weakening. Alternatives derived from natural products are being explored.: Aims: This systematic review was done to ... ...

Abstract	Context: Sodium hypochlorite, a gold standard for irrigation in endodontics, has disadvantages like toxicity and root dentin weakening. Alternatives derived from natural products are being explored. Aims: This systematic review was done to understand the clinical benefits of natural irrigants when compared with a standard irrigant, sodium hypochlorite. Settings and design registration: This systematic review was registered with PROSPERO (2018 CRD42018112837) METHODS AND MATERIAL: This review was done in conformation to the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA 2020) statement. In vivo studies using at least one natural irrigant and sodium hypochlorite (NaOCl) were included. Studies using them as medicaments were excluded. PubMed, Cochrane and SCOPUS were searched. RevMan tool for Risk of Bias 2 (RoB 2) and risk-of-bias tool to assess non-randomized studies of interventions (ROBINS-I) were used. GRADEpro was used to assess certainty of evidence. Results: Ten articles (6 RCTs and 4 clinical studies) on approximately 442 patients were included. Seven natural irrigants were evaluated clinically. Due to the heterogeneity, meta-analysis could not be conducted. Antimicrobial efficacy was found to be similar for castor oil, neem, garlic-lemon, noni, papaine and NaOCl. Neem, papaine-chloramine, neem-NaOCl and neem-CHX were superior, while propolis, miswak and garlic were inferior to NaOCl. Post-operative pain was less for neem. There was no significant difference between papaine-chloramine, garlic extract and sodium hypochlorite in clinical/radiographic success. Conclusions: The studied natural irrigants are not more efficacious than NaOCl. At the moment, they cannot replace NaOCl routinely and may only substitute in select cases.
MeSH term(s)	Humans ; Sodium Hypochlorite/pharmacology ; Chloramines ; Root Canal Irrigants/pharmacology ; Anti-Infective Agents ; Dental Pulp Cavity
Chemical Substances	Sodium Hypochlorite (DY38VHM5OD) ; chloramine (KW8K411A1P) ; Chloramines ; Root Canal Irrigants ; Anti-Infective Agents
Language	English
Publishing date	2023-02-18
Publishing country	Germany
Document type	Systematic Review ; Journal Article ; Review
ZDB-ID	1364490-7
ISSN	1436-3771 ; 1432-6981
ISSN (online)	1436-3771
ISSN	1432-6981
DOI	10.1007/s00784-023-04913-7
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Zs.A 4788: Show issues

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Article ; Online: Outcomes with chemotherapy in carcinoma penis: Experience from a tertiary cancer center.

Mailankody, Sharada / Radhakrishnan, Venkatraman / Raja, Anand / Ganesan, Trivadi S / Dhanushkodi, Manikandan / Sagar, Tenali Gnana

Indian journal of cancer

2023 Volume 60, Issue 3, Page(s) 396–402

Abstract: Background: Carcinoma penis is more common in India compared to the West. The role of chemotherapy in carcinoma penis is ambiguous. We analyzed the profile and outcomes of patients with carcinoma penis treated with chemotherapy.: Methods: We analyzed ...

Abstract	Background: Carcinoma penis is more common in India compared to the West. The role of chemotherapy in carcinoma penis is ambiguous. We analyzed the profile and outcomes of patients with carcinoma penis treated with chemotherapy. Methods: We analyzed the details of all patients with carcinoma penis treated at our institute between 2012 and 2015. We collected particulars regarding demography, clinical presentation, treatment details, toxicities, and outcomes of these patients. Event-free and overall (OS) survival were calculated from the time of diagnosis until documentation of disease relapse/progression or death for the patients with advanced carcinoma penis who were eligible for chemotherapy. Results: There were 171 patients with carcinoma penis treated at our institute during the study period including 54 (31.6%) patients with stage I, 49 (28.7%) patients with stage II, 24 (14.0%) patients with stage III, 25 (14.6%) patients with stage IV, and 19 (11.1%) patients with recurrent disease at presentation. The present study included 68 patients with advanced carcinoma penis (stages III and IV) who were eligible for chemotherapy, with a median age of 55 years (range: 27-79 years). Sixteen patients received paclitaxel and carboplatin (PC) and 26 patients cisplatin and 5-FluoroUracil (CF). Neoadjuvant chemotherapy (NACT) was given to four patients with stage III and nine patients with stage IV disease. Of the 13 patients given NACT, we observed a partial response in five (38.5%), stable disease in two (15.4%), and progressive disease in five (38.5%) evaluable patients. Six (46%) patients underwent surgery after NACT. Only 28/54 (52%) patients received adjuvant chemotherapy. After a median follow-up of 17.2 months, the 2-year OS rates were 95.8, 89, 62.7, 51.9, and 28.6% for stages I, II, III, IV, and recurrent disease, respectively. The 2-year OS of patients who were given chemotherapy versus those who were not given chemotherapy were 52.7 and 63.2%, respectively (P = 0.762). Conclusions: We report the real-world outcomes of two chemotherapeutic regimens used in consecutive patients with advanced carcinoma penis. Both PC and CF seemed effective and safe. However, approximately half of patients with advanced carcinoma penis do not receive the planned/indicated chemotherapy. We need further prospective trials regarding the sequencing, protocols and indications of chemotherapy in this malignancy.
MeSH term(s)	Male ; Humans ; Adult ; Middle Aged ; Aged ; Neoplasm Staging ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Cisplatin ; Carboplatin ; Carcinoma/therapy ; Chemotherapy, Adjuvant/methods ; Paclitaxel ; Neoadjuvant Therapy ; Penis
Chemical Substances	Cisplatin (Q20Q21Q62J) ; Carboplatin (BG3F62OND5) ; Paclitaxel (P88XT4IS4D)
Language	English
Publishing date	2023-02-26
Publishing country	India
Document type	Journal Article
ZDB-ID	410194-7
ISSN	1998-4774 ; 0019-509X
ISSN (online)	1998-4774
ISSN	0019-509X
DOI	10.4103/ijc.IJC_266_20
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