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  1. Article ; Online: Visualization techniques of the inferior alveolar nerve (IAN): a narrative review.

    Weckx, Annelies / Agbaje, Jimoh Olubanwo / Sun, Yi / Jacobs, Reinhilde / Politis, Constantinus

    Surgical and radiologic anatomy : SRA

    2016  Volume 38, Issue 1, Page(s) 55–63

    Abstract: ... techniques of the inferior alveolar nerve (IAN) in order to reduce the rates of nerve damage after ... Results: Five methods for IAN visualization were obtained from the search results, which are ... cone-beam computed tomography (CBCT) and automatic extraction of the IAN canal using computed tomography (CT ...

    Abstract Purpose: The purpose of this study was to produce an overview of the present visualization techniques of the inferior alveolar nerve (IAN) in order to reduce the rates of nerve damage after third molar (M3) removal and bilateral sagittal split osteotomy (BSSO).
    Methods: An electronic literature search was performed of the English-language scientific literature published prior to December 31, 2014 using the LIMO KU Leuven search platform. Information on the specifications of the different imaging techniques, their clinical application, advantages, disadvantages, and duration was extracted from 11 reports.
    Results: Five methods for IAN visualization were obtained from the search results, which are cone-beam computed tomography (CBCT) and automatic extraction of the IAN canal using computed tomography (CT), magnetic resonance imaging (MRI), panoramic radiography, endoscopy, and ultrasonographic visualization.
    Conclusion: The results of this study suggest that high-resolution MRI is the most commonly used method for direct visualization of the IAN. Six out of the eleven manuscripts use this technique. Recently, there have been some (experimental) modifications to the conventional MRI in the form of diffusion tensor tractography (DTT), phase-contrast magnetic resonance angiography (PC-MRA), and dental MRI. Future studies will focus on an intraoperative application of MRI to visualize the IAN during surgery.
    MeSH term(s) Cranial Nerve Injuries/etiology ; Cranial Nerve Injuries/prevention & control ; Humans ; Mandibular Nerve/diagnostic imaging ; Molar, Third/surgery ; Osteotomy, Sagittal Split Ramus/adverse effects
    Language English
    Publishing date 2016-01
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 632839-8
    ISSN 1279-8517 ; 0930-312X ; 0930-1038
    ISSN (online) 1279-8517
    ISSN 0930-312X ; 0930-1038
    DOI 10.1007/s00276-015-1510-z
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  2. Article ; Online: A CENTURY IS A SHORT TIME – NEW PERSPECTIVES ON THE ANGLO-BOER WAR/EDITED BY A CENTURY IS A SHORT TIME – NEW PERSPECTIVES ON THE ANGLO-BOER WAR BY INA SNYMAN, IAN LIEBENBERG, GERT VAN DER WESTHUIZEN, MARIAAN ROOS

    James Jacobs

    Scientia Militaria, Vol 34, Iss

    2011  Volume 1

    Abstract: The editors claim that this book attempts to further stimulate debate on the Anglo-Boer War of 1899-1902. Therefore, they included contributions from different disciplines, but with the main emphasis still on historical writing. They strived to continue ... ...

    Abstract The editors claim that this book attempts to further stimulate debate on the Anglo-Boer War of 1899-1902. Therefore, they included contributions from different disciplines, but with the main emphasis still on historical writing. They strived to continue the tradition to regard all historical debate as temporary and within the expression by the Dutch historian, Pieter Geyl, that history is a debate without end. From that point of view, the publication is timely and has the potential to enhance our comprehension of one of the events that had a profound influence on the history of South Africa. Because of the divergent approaches of the different authors, the different contributions are briefly analysed before a value judgement on the publication as a whole is made.
    Keywords Military Science ; U
    Subject code 900
    Language Afrikaans
    Publishing date 2011-08-01T00:00:00Z
    Publisher Stellenbosch University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Book ; Online ; E-Book: Tuberculosis and the tubercle bacillus

    Jacobs, William R. / McShane, Helen / Mizrahi, Valerie / Orme, Ian

    2018  

    Abstract: ... the second edition of Tuberculosis and the Tubercle Bacillus, edited by Jacobs, McShane, Mizrahi, and Orme ...

    Author's details edited by William R. Jacobs, Jr., Helen McShane, Valerie Mizrahi, Ian M. Orme
    Abstract One third of the world's population is infected with tuberculosis (TB), with about 10 million new cases annually. To combat TB and its agent, Mycobacterium tuberculosis, the World Health Organization launched The End TB Strategy, which aims to slash the suffering and cost of TB by 2035. This makes the second edition of Tuberculosis and the Tubercle Bacillus, edited by Jacobs, McShane, Mizrahi, and Orme, an extremely valuable resource for scientists and clinicians. The editors have gathered their colleagues from around the world to present the latest on the molecular biology of M. tuberculosis and related species, the host-pathogen interactions that enable invasion, and the host's immune response to M. tuberculosis infection. The basic, clinical, and translational research presented in this book supports the goals of WHO's End TB Strategy by driving toward the development of effective vaccines, rapid molecular diagnostics, and anti-TB drugs
    Keywords Tuberculosis / microbiology ; Mycobacterium tuberculosis ; Tuberculosis / immunology
    Subject code 614.5/42
    Language English
    Size 1 Online-Ressource (xiv, 726 Seiten), Illustrationen
    Edition 2nd edition
    Publisher ASM Press
    Publishing place Washington, DC
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019666262
    ISBN 978-1-55581-956-9 ; 9781555819552 ; 1-55581-956-7 ; 1555819559
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book: Pediatric laryngotracheal reconstruction with tissue-engineered cartilage in a rabbit model

    Jacobs, Ian N. / Redden, Robert A. / Goldberg, Rachel / Hast, Michael / Salowe, Rebecca / Mauck, Robert L. / Doolin, Edward J.

    (The laryngoscope ; volume 126, supplement 1 (January 2016))

    2016  

    Author's details Ian N. Jacobs, MD; Robert A. Redden, BSE, MSE; Rachel Goldberg, BA; Michael Hast, BSE; Rebecca Salowe, BSE; Robert L. Mauck, PhD; Edward J. Doolin, MD
    Series title The laryngoscope ; volume 126, supplement 1 (January 2016)
    Collection
    Language English
    Size S21 Seiten, Illustrationen
    Publisher Wiley
    Publishing place Hoboken, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT018988506
    Database Catalogue ZB MED Medicine, Health

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  5. Book: Ovarian cancer

    Jacobs, Ian J.

    [meetings held by the HHMT ...]

    2002  

    Institution Helene Harris Memorial Trust
    Author's details I. J. Jacobs ... [In collaboration with the Helene Harris Memorial Trust]
    Keywords Ovarian Neoplasms ; Eierstockkrebs
    Subject Ovarialkarzinom ; Ovarialcarcinom ; Ovarialkrebs
    Language English
    Size XIII, 427 S. : Ill., graph. Darst.
    Publisher Oxford Univ. Press
    Publishing place Oxford u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT013311262
    ISBN 0-19-850826-3 ; 978-0-19-850826-7
    Database Catalogue ZB MED Medicine, Health

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    2002 A 1414 order for loan Magazin

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  6. Article ; Online: Current management of aerodigestive foreign bodies in children.

    Jacobs, Ian N / Jatana, Kris R

    Seminars in pediatric surgery

    2021  Volume 30, Issue 3, Page(s) 151064

    Abstract: Foreign bodies ingestion or aspiration events in children can be a source of morbidity and mortality. In most cases, removal by a coordinated endoscopy can be performed when there is the availability of equipment and support staff for pediatric care. ... ...

    Abstract Foreign bodies ingestion or aspiration events in children can be a source of morbidity and mortality. In most cases, removal by a coordinated endoscopy can be performed when there is the availability of equipment and support staff for pediatric care. Close communication with the anesthesia, surgeon and operating room support staff is essential and rehearsing with a facsimile of the foreign body is useful. In certain cases, such as sharp foreign bodies or button batteries the endoscopy should be performed immediately.
    MeSH term(s) Child ; Electric Power Supplies ; Endoscopy ; Foreign Bodies/diagnosis ; Foreign Bodies/surgery ; Humans ; Infant ; Retrospective Studies
    Language English
    Publishing date 2021-05-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1133381-9
    ISSN 1532-9453 ; 1055-8586
    ISSN (online) 1532-9453
    ISSN 1055-8586
    DOI 10.1016/j.sempedsurg.2021.151064
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    Zs.A 3544: Show issues Location:
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  7. Article ; Online: Mycobacterium smegmatis: The Vanguard of Mycobacterial Research.

    Sparks, Ian L / Derbyshire, Keith M / Jacobs, William R / Morita, Yasu S

    Journal of bacteriology

    2023  Volume 205, Issue 1, Page(s) e0033722

    Abstract: The genus Mycobacterium contains several slow-growing human pathogens, including Mycobacterium tuberculosis, Mycobacterium leprae, and Mycobacterium avium. Mycobacterium smegmatis is a nonpathogenic and fast growing species within this genus. In 1990, a ... ...

    Abstract The genus Mycobacterium contains several slow-growing human pathogens, including Mycobacterium tuberculosis, Mycobacterium leprae, and Mycobacterium avium. Mycobacterium smegmatis is a nonpathogenic and fast growing species within this genus. In 1990, a mutant of M. smegmatis, designated mc
    MeSH term(s) Humans ; Mycobacterium smegmatis/genetics ; Escherichia coli/genetics ; Mycobacterium tuberculosis/genetics ; Tuberculosis ; Isoniazid
    Chemical Substances Isoniazid (V83O1VOZ8L)
    Language English
    Publishing date 2023-01-04
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 2968-3
    ISSN 1098-5530 ; 0021-9193
    ISSN (online) 1098-5530
    ISSN 0021-9193
    DOI 10.1128/jb.00337-22
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  8. Article ; Online: A Pilot Study of Decellularized Cartilage for Laryngotracheal Reconstruction in a Neonatal Pig Model.

    Gehret, Paul M / Dumas, Alexandra A / Jacobs, Ian N / Gottardi, Riccardo

    The Laryngoscope

    2023  Volume 134, Issue 2, Page(s) 807–814

    Abstract: Objective: Severe subglottic stenosis develops as a response to intubation in 1% of the >200,000 neonatal intensive care unit infants per year and may require laryngotracheal reconstruction (LTR) with autologous hyaline cartilage. Although effective, ... ...

    Abstract Objective: Severe subglottic stenosis develops as a response to intubation in 1% of the >200,000 neonatal intensive care unit infants per year and may require laryngotracheal reconstruction (LTR) with autologous hyaline cartilage. Although effective, LTR is limited by comorbidities, severity of stenosis, and graft integration. In children, there is a significant incidence of restenosis requiring revision surgery. Tissue engineering has been proposed to develop alterative grafting options to improve outcomes and eliminate donor-site morbidity. Our objective is to engineer a decellularized, channel-laden xenogeneic cartilage graft, that we deployed in a proof-of-concept, neonatal porcine LTR model.
    Methods: Meniscal porcine cartilage was freeze-thawed and washed with pepsin/elastase to decellularize and create microchannels. A 6 × 10-mm decellularized cartilage graft was then implanted in 4 infant pigs in an anterior cricoid split. Airway patency and host response were monitored endoscopically until sacrifice at 12 weeks, when the construct phenotype, cricoid expansion, mechanics, and histomorphometry were evaluated.
    Results: The selective digestion of meniscal components yielded decellularized cartilage with cell-size channels. After LTR with decellularized meniscus, neonatal pigs were monitored via periodic endoscopy observing re-epithelization, integration, and neocartilage formation. At 12 weeks, the graft appeared integrated and exhibited airway expansion of 4 mm in micro-CT and endoscopy. Micro-CT revealed a larger lumen compared with age-matched controls. Finally, histology showed significant neocartilage formation.
    Conclusion: Our neonatal porcine LTR model with a decellularized cartilage graft is a novel approach to tissue engineered pediatric LTR. This pilot study sets the stage for "off-the-shelf" graft procurement and future optimization of MEND for LTR.
    Level of evidence: NA Laryngoscope, 134:807-814, 2024.
    MeSH term(s) Infant ; Infant, Newborn ; Child ; Humans ; Animals ; Swine ; Pilot Projects ; Constriction, Pathologic/surgery ; Plastic Surgery Procedures ; Cartilage/transplantation ; Laryngostenosis/surgery
    Language English
    Publishing date 2023-09-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80180-x
    ISSN 1531-4995 ; 0023-852X
    ISSN (online) 1531-4995
    ISSN 0023-852X
    DOI 10.1002/lary.31017
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  9. Article ; Online: Anatomic Considerations of esophageal button battery ingestion for outcomes and imaging.

    Cohen, William G / Mchugh, Moira / Giordano, Terri / Jacobs, Ian N

    International journal of pediatric otorhinolaryngology

    2023  Volume 176, Page(s) 111803

    Abstract: Introduction: Button batteries (BB) are a source of significant morbidity and mortality in young children. Little data is available regarding associations between esophageal impaction location and outcomes or need for surveillance imaging.: Methods: ... ...

    Abstract Introduction: Button batteries (BB) are a source of significant morbidity and mortality in young children. Little data is available regarding associations between esophageal impaction location and outcomes or need for surveillance imaging.
    Methods: All patients treated at a single institution following BB ingestion between 2018 and 2022 were included for retrospective chart review.
    Results: Twenty patients were treated at our institution BBs were located, or most significant damage observed, in the cervical esophagus (n = 10, 50 %), followed by thoracic esophagus (n = 6, 30 %), and abdominal esophagus (n = 4, 20 %). Patients with cervical esophageal impaction were younger (482 [370-866] days), than those with thoracic (1395 [871-2369] days) or abdominal esophageal impaction (2021.5 [1230.5-3419.5] days) (p = 0.003). Zargar Mucosal Injury Grade was significantly more severe in patients with cervical button battery impaction; 8/10 (80 %) had a ≥Grade IIIB injury, compared to 2/6 (33.3 %) thoracic impactions and 0/4 (0 %) abdominal impactions (p = 0.002). All patients who developed persistent esophageal stenosis (n = 6) had cervical battery impactions (6, 60 %, p = 0.015). Both TEFs (2/2) had anterior facing anode, while both (2/2) esophageal perforations had posterior. Only 1/20 (5 %) patients, and 1/7 (14.3 %) with serious complications, had a serious complication detected on routine, rather than clinically indicated follow-up surveillance.
    Conclusions: In our population, cervical BB impaction occurred more frequently in younger children, was associated with more severe mucosal injury, and had higher risk of stenosis. Nearly all complications were detected on clinically indicated rather than postoperative surveillance imaging.
    MeSH term(s) Child ; Humans ; Child, Preschool ; Retrospective Studies ; Foreign Bodies/complications ; Foreign Bodies/diagnostic imaging ; Foreign Bodies/surgery ; Esophagus/diagnostic imaging ; Esophagus/injuries ; Electric Power Supplies ; Eating
    Language English
    Publishing date 2023-11-24
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 754501-0
    ISSN 1872-8464 ; 0165-5876
    ISSN (online) 1872-8464
    ISSN 0165-5876
    DOI 10.1016/j.ijporl.2023.111803
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  10. Article ; Online: Multitype Electronic Interactions in Precursor Solutions of Molecular Doped P3HT Polymer.

    Tiwari, Vandana / Li, Xin / Li, Zheng / Jacobs, Ian E / Duan, Hong-Guang / Sirringhaus, Henning / Miller, R J Dwayne / Jha, Ajay

    The journal of physical chemistry. B

    2024  Volume 128, Issue 13, Page(s) 3249–3257

    Abstract: Spin-casting of molecularly doped polymer solution mixtures is one of the commonly used methods to obtain conductive organic semiconductor films. In spin-casted films, electronic interaction between the dopant and polymer is one of the crucial factors ... ...

    Abstract Spin-casting of molecularly doped polymer solution mixtures is one of the commonly used methods to obtain conductive organic semiconductor films. In spin-casted films, electronic interaction between the dopant and polymer is one of the crucial factors that dictates the doping efficiency. Here, we investigate excitonic couplings using ultrafast two-dimensional electronic spectroscopy to examine the different types of electronic interactions in ion pairs of the prototype F
    Language English
    Publishing date 2024-03-20
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5207
    ISSN (online) 1520-5207
    DOI 10.1021/acs.jpcb.4c00584
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