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Article ; Online: A Commentary on: Serum Trace Element Concentrations in Rheumatoid Arthritis.

Turrubiates-Hernández, Francisco Javier / Hernández-Bello, Jorge / Baños-Hernández, Christian Johana / Muñoz-Valle, José Francisco

Biological trace element research

2022 Volume 201, Issue 5, Page(s) 2682–2683

MeSH term(s)	Humans ; Trace Elements ; Arthritis, Rheumatoid
Chemical Substances	Trace Elements
Language	English
Publishing date	2022-06-13
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	445336-0
ISSN	1559-0720 ; 0163-4984
ISSN (online)	1559-0720
ISSN	0163-4984
DOI	10.1007/s12011-022-03319-y
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Zs.B 2323: Show issues

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Article: Vitamin A Positively Correlates with Secretory Immunoglobulin A: A Cross-Sectional Study in Omicron COVID-19 Outpatients.

Turrubiates-Hernández, Francisco Javier / García-Arellano, Samuel / Herrera-Jiménez, Laura Elena / González-Estevez, Guillermo / Márquez-Sandoval, Fabiola / Padilla-Bórquez, Diana Lourdes / Ceja-Gálvez, Hazael Ramiro / Vega-Magaña, Natali / Nicoletti, Ferdinando / Muñoz-Ríos, Guillermina / Muñoz-Valle, José Francisco

Journal of clinical medicine

2024 Volume 13, Issue 6

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2024-03-07
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm13061538
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Article ; Online: Vitamin D in Depression: A Potential Bioactive Agent to Reduce Suicide and Suicide Attempt Risk.

Somoza-Moncada, María Montserrat / Turrubiates-Hernández, Francisco Javier / Muñoz-Valle, José Francisco / Gutiérrez-Brito, Jesús Alberto / Díaz-Pérez, Saúl Alberto / Aguayo-Arelis, Adriana / Hernández-Bello, Jorge

Nutrients

2023 Volume 15, Issue 7

Abstract: Suicide is one of the leading causes of death worldwide. According to the World Health Organization (WHO), every year, more than 700 thousand people die from this cause. Therefore, suicide is a public health issue. The complex interaction between ... ...

Abstract	Suicide is one of the leading causes of death worldwide. According to the World Health Organization (WHO), every year, more than 700 thousand people die from this cause. Therefore, suicide is a public health issue. The complex interaction between different factors causes suicide; however, depression is one of the most frequent factors in people who have attempted suicide. Several studies have reported that vitamin D deficiency may be a relevant risk factor for depression, and vitamin D supplementation has shown promising effects in the adjunctive treatment of this mood disorder. Among the beneficial mechanisms of vitamin D, it has been proposed that it may enhance serotonin synthesis and modulate proinflammatory cytokines since low serotonin levels and systemic inflammation have been associated with depression and suicide. The present narrative review shows the potential pathogenic role of vitamin D deficiency in depression and suicide and the potential benefits of vitamin D supplementation to reduce their risk.
MeSH term(s)	Humans ; Suicide, Attempted ; Vitamin D/therapeutic use ; Depression/drug therapy ; Suicidal Ideation ; Serotonin ; Vitamins/therapeutic use ; Vitamin D Deficiency/complications ; Vitamin D Deficiency/drug therapy
Chemical Substances	Vitamin D (1406-16-2) ; Serotonin (333DO1RDJY) ; Vitamins
Language	English
Publishing date	2023-04-04
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu15071765
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Article ; Online: Potential immunomodulatory effects of vitamin D in the prevention of severe coronavirus disease 2019: An ally for Latin America (Review).

Turrubiates-Hernández, Francisco Javier / Sánchez-Zuno, Gabriela Athziri / González-Estevez, Guillermo / Hernández-Bello, Jorge / Macedo-Ojeda, Gabriela / Muñoz-Valle, José Francisco

International journal of molecular medicine

2021 Volume 47, Issue 4

Abstract: Currently, the world is under a pandemic of severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), responsible for coronavirus disease 2019 (COVID‑19). This disease is characterized by a respiratory syndrome that can progress to an acute ... ...

Abstract	Currently, the world is under a pandemic of severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), responsible for coronavirus disease 2019 (COVID‑19). This disease is characterized by a respiratory syndrome that can progress to an acute respiratory distress syndrome. To date, limited effective therapies are available for the prevention or treatment of COVID‑19; therefore, it is necessary to propose novel treatment options with immunomodulatory effects. Vitamin D serves functions in bone health and has been recently reported to exert protective effects against respiratory infections. Observational studies have demonstrated an association between vitamin D deficiency and a poor prognosis of COVID‑19; this is alarming as vitamin D deficiency is a global health problem. In Latin America, the prevalence of vitamin D deficiency is unknown, and currently, this region is in the top 10 according to the number of confirmed COVID‑19 cases. Supplementation with vitamin D may be a useful adjunctive treatment for the prevention of COVID‑19 complications. The present review provides an overview of the current knowledge of the potential immunomodulatory effects of vitamin D in the prevention of COVID‑19 and sets out vitamin D recommendations for the Latin American population.
MeSH term(s)	Bone and Bones ; COVID-19/complications ; COVID-19/prevention & control ; Dietary Supplements ; Humans ; Immunologic Factors/therapeutic use ; Latin America ; Prevalence ; Renin-Angiotensin System ; Respiratory Tract Infections/virology ; Vitamin D/therapeutic use ; Vitamin D Deficiency/complications
Chemical Substances	Immunologic Factors ; Vitamin D (1406-16-2)
Language	English
Publishing date	2021-02-04
Publishing country	Greece
Document type	Journal Article ; Review
ZDB-ID	1444428-8
ISSN	1791-244X ; 1107-3756
ISSN (online)	1791-244X
ISSN	1107-3756
DOI	10.3892/ijmm.2021.4865
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Article: Participación de la vitamina A en la producción de IgA secretora en el epitelio del tracto respiratorio para la potencial protección de infección por SARS-CoV-2.

Turrubiates-Hernández, Francisco Javier / Hernández-Bello, Jorge / Oregón-Romero, Edith / González-Estevez, Guillermo / Muñoz-Valle, José Francisco

Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)

2021 Volume 68, Issue 3, Page(s) 185–197

Abstract: SARS-CoV-2 continues to infect thousands of people around the world. It has been established that the main transmission mechanism of this virus is via airborne route, which is why it initially infects the respiratory tract. Currently, the effectiveness ... ...

Title translation	The involvement of vitamin A in the production of secretory IgA in the respiratory epithelium for potential protection against SARS-CoV-2 infection.
Abstract	SARS-CoV-2 continues to infect thousands of people around the world. It has been established that the main transmission mechanism of this virus is via airborne route, which is why it initially infects the respiratory tract. Currently, the effectiveness of medications used against COVID-19 is limited, and although immunization programs have been initiated, there is international inequality in the distribution of vaccines. Accordingly, the search for adjuvant therapies continues to be an alternative for research. Supplementation with vitamin A has been associated to the decrease of mortality from infection; this effect could be mediated by retinoic acid (RA), which is the active metabolite of vitamin A that exerts immunomodulatory functions. According to preclinical studies, RA favors the production of secretory immunoglobulin A (IgA) in the respiratory tract. In addition to this, the retinol-binding protein has been correlated with the concentration of IgA and neutralizing antibodies in patients with influenza. Therefore, this review aims to address the involvement of vitamin A in the production of secretory IgA in the respiratory epithelium in order to highlight its potential protection against SARS-CoV-2 infection.
MeSH term(s)	Antibodies, Viral ; COVID-19 ; Humans ; Immunoglobulin A, Secretory ; Respiratory Mucosa ; SARS-CoV-2 ; Vitamin A
Chemical Substances	Antibodies, Viral ; Immunoglobulin A, Secretory ; Vitamin A (11103-57-4)
Language	Spanish
Publishing date	2021-10-11
Publishing country	Mexico
Document type	Journal Article ; Review
ZDB-ID	639125-4
ISSN	0002-5151
ISSN	0002-5151
DOI	10.29262/ram.v68i3.977
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Article: Efficacy and Safety of Heterologous Booster Vaccination after Ad5-nCoV (CanSino Biologics) Vaccine: A Preliminary Descriptive Study.

Muñoz-Valle, José Francisco / Sánchez-Zuno, Gabriela Athziri / Matuz-Flores, Mónica Guadalupe / Hernández-Ramírez, Cristian Oswaldo / Díaz-Pérez, Saúl Alberto / Baños-Hernández, Christian Johana / Turrubiates-Hernández, Francisco Javier / Vega-Magaña, Alejandra Natali / Hernández-Bello, Jorge

Vaccines

2022 Volume 10, Issue 3

Abstract: Several studies have reported the benefits and safety of heterologous vaccination among different approved vaccines; however, there are no specific reports on the effects of vaccination with the Ad5-nCoV and other vaccines of the same or different ... ...

Abstract	Several studies have reported the benefits and safety of heterologous vaccination among different approved vaccines; however, there are no specific reports on the effects of vaccination with the Ad5-nCoV and other vaccines of the same or different technologies. In the present study, we evaluated the neutralizing antibodies percentage against SARS-CoV-2 in Mexican patients immunized with the Ad5-nCoV vaccine six months after its application. Moreover, the effect of the heterologous vaccination with the Ad5-nCoV vaccine and a booster dose of ChAdOx1-S-Nov-19, Ad26.COV2.S, BNT162b2, or mRNA-127 were determined. Our results suggest that a heterologous regimen of one dose with Ad5-nCoV vaccine followed by a booster dose of a different vaccine is safe and induces a stronger humoral immune response.
Language	English
Publishing date	2022-03-05
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2703319-3
ISSN	2076-393X
ISSN	2076-393X
DOI	10.3390/vaccines10030400
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Article ; Online: The Relevance of Selenium Status in Rheumatoid Arthritis.

Turrubiates-Hernández, Francisco Javier / Márquez-Sandoval, Yolanda Fabiola / González-Estevez, Guillermo / Reyes-Castillo, Zyanya / Muñoz-Valle, José Francisco

Nutrients

2020 Volume 12, Issue 10

Abstract: Rheumatoid arthritis (RA) is an autoimmune and inflammatory disease that can cause joint damage. Among the environmental risk factors, diet plays an important role because it can aggravate or attenuate inflammation. Selenium (Se) is considered an ... ...

Abstract	Rheumatoid arthritis (RA) is an autoimmune and inflammatory disease that can cause joint damage. Among the environmental risk factors, diet plays an important role because it can aggravate or attenuate inflammation. Selenium (Se) is considered an essential trace element since it is a structural component of antioxidant enzymes; however, its concentration can be affected by diet, drugs and genetic polymorphisms. Studies have reported that RA patients have a deficient diet in some food groups that is associated with parameters of disease activity. Furthermore, it has been shown that there is an alteration in serum Se levels in this population. Although some clinical trials have been conducted in the past to analyze the effect of Se supplementation in RA, no significant results were obtained. Contrastingly, experimental studies that have evaluated the effect of novel Se nanoparticles in RA-induced models have shown promising results on the restoration of antioxidant enzyme levels. In particular, glutathione peroxidase (GPx) is an important selenoprotein that could have a modulating effect on inflammation in RA. Considering that RA patients present an inflammatory and oxidative state, the aim of this review is to give an overview of the current knowledge about the relevance of Se status in RA.
MeSH term(s)	Animals ; Antioxidants/analysis ; Arthritis, Rheumatoid/blood ; Arthritis, Rheumatoid/complications ; Diet/adverse effects ; Diet, Healthy/methods ; Dietary Supplements ; Glutathione Peroxidase/analysis ; Humans ; Inflammation ; Nutritional Status ; Oxidation-Reduction/drug effects ; Selenium/blood ; Selenium/deficiency ; Selenoproteins/analysis ; Trace Elements/blood ; Trace Elements/deficiency
Chemical Substances	Antioxidants ; Selenoproteins ; Trace Elements ; Glutathione Peroxidase (EC 1.11.1.9) ; Selenium (H6241UJ22B)
Language	English
Publishing date	2020-09-30
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu12103007
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Article: The Relevance of Selenium Status in Rheumatoid Arthritis

Turrubiates-Hernández, Francisco Javier / Márquez-Sandoval, Yolanda Fabiola / González-Estevez, Guillermo / Reyes-Castillo, Zyanya / Muñoz-Valle, José Francisco

Nutrients. 2020 Sept. 30, v. 12, no. 10

2020

Abstract	Rheumatoid arthritis (RA) is an autoimmune and inflammatory disease that can cause joint damage. Among the environmental risk factors, diet plays an important role because it can aggravate or attenuate inflammation. Selenium (Se) is considered an essential trace element since it is a structural component of antioxidant enzymes; however, its concentration can be affected by diet, drugs and genetic polymorphisms. Studies have reported that RA patients have a deficient diet in some food groups that is associated with parameters of disease activity. Furthermore, it has been shown that there is an alteration in serum Se levels in this population. Although some clinical trials have been conducted in the past to analyze the effect of Se supplementation in RA, no significant results were obtained. Contrastingly, experimental studies that have evaluated the effect of novel Se nanoparticles in RA-induced models have shown promising results on the restoration of antioxidant enzyme levels. In particular, glutathione peroxidase (GPx) is an important selenoprotein that could have a modulating effect on inflammation in RA. Considering that RA patients present an inflammatory and oxidative state, the aim of this review is to give an overview of the current knowledge about the relevance of Se status in RA.
Keywords	antioxidant enzymes ; blood serum ; clinical trials ; diet ; drugs ; food groups ; genetic polymorphism ; glutathione peroxidase ; inflammation ; knowledge ; models ; nanoparticles ; nutrients ; patients ; population ; rheumatoid arthritis ; risk factors ; selenium ; selenoproteins
Language	English
Dates of publication	2020-0930
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
Note	NAL-light
ZDB-ID	2518386-2
ISSN	2072-6643
ISSN	2072-6643
DOI	10.3390/nu12103007
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: A review: Antibody-dependent enhancement in COVID-19: The not so friendly side of antibodies.

Sánchez-Zuno, Gabriela Athziri / Matuz-Flores, Mónica Guadalupe / González-Estevez, Guillermo / Nicoletti, Ferdinando / Turrubiates-Hernández, Francisco Javier / Mangano, Katia / Muñoz-Valle, José Francisco

International journal of immunopathology and pharmacology

2021 Volume 35, Page(s) 20587384211050199

Abstract: The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), represents an unprecedented global public health emergency with economic and social consequences. One of the main concerns in the ... ...

Abstract	The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), represents an unprecedented global public health emergency with economic and social consequences. One of the main concerns in the development of vaccines is the antibody-dependent enhancement phenomenon, better known as ADE. In this review, we provide an overview of SARS-CoV-2 infection as well as the immune response generated by the host. On the bases of this principle, we also describe what is known about the ADE phenomenon in various viral infections and its possible role as a limiting factor in the development of new vaccines and therapeutic strategies.
MeSH term(s)	Adaptive Immunity ; Antibodies, Viral/immunology ; Antibody-Dependent Enhancement ; COVID-19/immunology ; COVID-19/prevention & control ; COVID-19/virology ; COVID-19 Vaccines/therapeutic use ; Host-Pathogen Interactions ; Humans ; Immunity, Innate ; SARS-CoV-2/immunology ; SARS-CoV-2/pathogenicity ; Vaccination
Chemical Substances	Antibodies, Viral ; COVID-19 Vaccines
Language	English
Publishing date	2021-10-10
Publishing country	England
Document type	Letter ; Review
ZDB-ID	645171-8
ISSN	2058-7384 ; 0394-6320
ISSN (online)	2058-7384
ISSN	0394-6320
DOI	10.1177/20587384211050199
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Zs.A 2537: Show issues

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Article ; Online: Association of Food Intake Quality with Vitamin D in SARS-CoV-2 Positive Patients from Mexico: A Cross-Sectional Study.

González-Estevez, Guillermo / Turrubiates-Hernández, Francisco Javier / Herrera-Jiménez, Laura Elena / Sánchez-Zuno, Gabriela Athziri / Herrera-Godina, Melva Guadalupe / Muñoz-Valle, José Francisco

International journal of environmental research and public health

2021 Volume 18, Issue 14

Abstract: One of the micronutrients that has attracted the most attention in relation to COVID-19 is vitamin D. Although several factors affect its sufficiency; it has been argued that an optimal diet can ensure the intake of micronutrients with effects on immune ... ...

Abstract	One of the micronutrients that has attracted the most attention in relation to COVID-19 is vitamin D. Although several factors affect its sufficiency; it has been argued that an optimal diet can ensure the intake of micronutrients with effects on immune response. Therefore, in this work we aimed to evaluate the food intake quality of SARS-CoV-2 positive Mexican patients and some of the common factors related to vitamin D deficiency. We conducted a cross-sectional study in 40 SARS-CoV-2 positive patients. Serum samples and clinical parameters were collected. Micronutrient intake and food intake quality were assessed with a 24-h dietary recall and the Mini-ECCA v.2, respectively. Thirty-eight percent of the sample had a healthy food intake. The median 25(OH)D concentration was 22.7 ng/mL. A considerable insufficient intake of micronutrients with immunomodulatory effects such as vitamin D (
MeSH term(s)	COVID-19 ; Cross-Sectional Studies ; Eating ; Humans ; Mexico/epidemiology ; Micronutrients ; SARS-CoV-2 ; Vitamin D ; Vitamin D Deficiency
Chemical Substances	Micronutrients ; Vitamin D (1406-16-2)
Language	English
Publishing date	2021-07-07
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph18147266
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