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Article: Toward an integrative socio-cognitive approach in autism spectrum disorder: NEAR method adaptation-study protocol.

Bahri, Jihene / Abbes, Zeineb S / Ben Yahia, Houda / Halayem, Soumeyya / Jelili, Selima / Hajri, Melek / Amado, Isabelle / Medalia, Alice / Bouden, Asma

Frontiers in psychiatry

2023 Volume 14, Page(s) 940066

Language	English
Publishing date	2023-05-24
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564218-2
ISSN	1664-0640
ISSN	1664-0640
DOI	10.3389/fpsyt.2023.940066
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Cognitive deficits in children with autism spectrum disorders: Toward an integrative approach combining social and non-social cognition.

Hajri, Melek / Abbes, Zeineb / Yahia, Houda Ben / Jelili, Selima / Halayem, Soumeyya / Mrabet, Ali / Bouden, Asma

Frontiers in psychiatry

2022 Volume 13, Page(s) 917121

Abstract: Autism spectrum disorder (ASD) is associated with neurocognitive impairment, including executive dysfunctioning and social cognition (SC) deficits. Cognitive remediation (CR) is a behavioral training-based intervention aiming to improve cognitive ... ...

Abstract	Autism spectrum disorder (ASD) is associated with neurocognitive impairment, including executive dysfunctioning and social cognition (SC) deficits. Cognitive remediation (CR) is a behavioral training-based intervention aiming to improve cognitive processes. Its first use in psychiatry interested patients with schizophrenia, in whom promising results have been shown. Integrated CR programs targeting both social and non-social cognition have demonstrated to be effective in improving both cognitive domains and functional outcomes. CR studies in children and adolescents with ASD are still new, those regarding CR approaches combining social and executive functioning remediation are scares. One study examining the efficacy of cognitive enhancement therapy (CET) for improving cognitive abilities in ADS adults, showed significant differential increases in neurocognitive function and large social-cognitive improvements. Therefore, taking into account the overlap between ASD and schizophrenia, and considering the close link between executive functions (EF) and SC, we suggest that integrative approach in ASD could result in better outcomes. The present perspective aimed to highlight cognitive remediation (CR) programs contributions in ASD (especially in children and adolescents), and to discuss the value of combining social and non-social programs.
Language	English
Publishing date	2022-08-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564218-2
ISSN	1664-0640
ISSN	1664-0640
DOI	10.3389/fpsyt.2022.917121
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Article ; Online: Profil épidémiologique et clinique des tentatives de suicide chez l'enfant et l'adolescent en Tunisie en post révolution.

Charfi, Fatma / Harbaoui, Azza / Skhiri, Afef / Abbès, Zeineb / Belhadj, Ahlem / Halayem, Soumaya / Bouden, Asma

The Pan African medical journal

2019 Volume 32, Page(s) 204

Abstract: Background: Suicidal behaviors are increasing in Tunisia at younger and younger ages. This study aims to describe the sociodemographic and clinical profile of suicide attempts in children and adolescents.: Methods: We conducted a cross-sectional and ... ...

Title translation	Epidemiological and clinical profile of suicide attempts in Tunisian children and adolescents after the revolution.
Abstract	Background: Suicidal behaviors are increasing in Tunisia at younger and younger ages. This study aims to describe the sociodemographic and clinical profile of suicide attempts in children and adolescents. Methods: We conducted a cross-sectional and descriptive study, including 50 suicidal individuals, recruited in the Child Psychiatry Department at the Razi Hospital in Manouba and in two Departments in Tunisia (Intensive Care and Reanimation Department and Department of Pediatrics) between July 2012 and June 2013. We identified the socio-demographic and clinical factors, the histories of abuse, subjects' education, the characteristics of the attempted suicides (TS), suicidal ideation assessed by the Suicidal Intent Scale and psychopathological disorders diagnosed using the Mini-International Neuropsychiatric Interview. Results: The sex-ratio was 0.56, the average age was 12.4 years ranging from 7 to 16 years. School failure or dropout were found in 86% of suicidal individuals. In 38% of cases suicidal behavior was recurrent; the subjects had a history of self-mutilation to the same extent. A context of abuse was reported in 46% of cases. Drug ingestion was the most common means of suicide, psychotropic drugs were the most common substances used. There was a significant gender difference in the use of the means of suicide: the boys mainly used physical means (P=0.04) while the girls poisoning (P=0.001). Suicidal intent was high in 44% of cases. A major depressive episode and adjustment disorder were the most common disorders found (58% and 24% of cases respectively). Conclusion: Depressive disorders and abuse are risk factors of TS in children and adolescents, these factors should be considered when implementing suicide prevention strategies for this population.
MeSH term(s)	Adjustment Disorders/epidemiology ; Adolescent ; Child ; Child Abuse/statistics & numerical data ; Cross-Sectional Studies ; Depressive Disorder, Major/epidemiology ; Female ; Humans ; Male ; Mental Disorders/epidemiology ; Psychiatric Status Rating Scales ; Psychotropic Drugs/administration & dosage ; Recurrence ; Risk Factors ; Self-Injurious Behavior/epidemiology ; Sex Factors ; Suicidal Ideation ; Suicide, Attempted/psychology ; Suicide, Attempted/statistics & numerical data ; Tunisia/epidemiology
Chemical Substances	Psychotropic Drugs
Language	French
Publishing date	2019-04-26
Publishing country	Uganda
Document type	Journal Article
ZDB-ID	2514347-5
ISSN	1937-8688 ; 1937-8688
ISSN (online)	1937-8688
ISSN	1937-8688
DOI	10.11604/pamj.2019.32.204.15477
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Article ; Online: Profil épidémiologique et clinique des tentatives de suicide chez l'enfant et l'adolescent en Tunisie en post révolution

Fatma Charfi / Azza Harbaoui / Afef Skhiri / Zeineb Abbès / Ahlem Belhadj / Soumaya Halayem / Asma Bouden

The Pan African Medical Journal, Vol 32, Iss

2019 Volume 204

Abstract: INTRODUCTION: Les conduites suicidaires sont en augmentation en Tunisie et touchent une population de plus en plus jeune. Le but de notre étude était de décrire le profil sociodémographique et clinique des tentatives de suicide chez l'enfant et l' ... ...

Abstract	INTRODUCTION: Les conduites suicidaires sont en augmentation en Tunisie et touchent une population de plus en plus jeune. Le but de notre étude était de décrire le profil sociodémographique et clinique des tentatives de suicide chez l'enfant et l'adolescent. METHODES: cette étude était transversale et descriptive, incluant 50 suicidants, recrutés au service de pédopsychiatrie de l'Hôpital Razi de la Manouba et dans deux services de réanimation et de pédiatrie de Tunis, entre juillet 2012 et juin 2013. Ont été relevés les facteurs sociodémographiques et cliniques, les antécédents de maltraitance, la scolarité, les caractéristiques de la TS, l'intentionnalité suicidaire évaluée par le Suicide Intent Scale, et les troubles psychopathologiques à l'aide du Mini-International Neuropsychiatric Interview. RESULTATS: le sex-ratio était de 0,56, la moyenne d'âge était de 12,4 ans avec des extrêmes de 7 à 16 ans. Un échec ou un fléchissement scolaire a concerné 86% des suicidants. Dans 38% des cas il s'agissait de récidive; des antécédents d'automutilations ont été retrouvés dans les mêmes proportions. Un contexte de maltraitance a été signalé dans 46% des cas. L'ingestion médicamenteuse était le moyen le plus fréquent, les psychotropes étant les plus représentés. Une différence significative entre le genre a été retrouvée dans le recours aux moyens suicidaires, ainsi les garçons ont eu davantage recours aux moyens physiques (p=0,04) et les filles aux intoxications (p=0,001). L'intentionnalité suicidaire était élevée dans 44%. Un épisode dépressif majeur et le trouble de l'adaptation étaient les troubles les plus fréquemment retrouvés dans respectivement 58% et 24% des cas. CONCLUSION: les troubles dépressifs et la maltraitance se dégagent comme des facteurs de risque des TS chez les enfants et les adolescents, ces facteurs doivent être pris en considération dans les stratégies de prévention du suicide dans cette population.
Keywords	tentative de suicide ; enfant ; adolescent ; troubles mentaux ; Medicine ; R
Language	English
Publishing date	2019-04-01T00:00:00Z
Publisher	The Pan African Medical Journal
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Assessment of theory of mind in Tunisian verbal children with autism spectrum disorder.

Jelili, Selima / Halayem, Soumeyya / Rajhi, Olfa / Abbes, Zeineb / Mansour, Hajer Ben / Ouanes, Sami / Taamallah, Amal / Ennaifer, Selima / Ben Yahia, Houda / Ghazzei, Melek / Nabli, Ahmed / Hajri, Malek / Fakhfakh, Radhouane / Mrabet, Ali / Bouden, Asma

Frontiers in psychiatry

2022 Volume 13, Page(s) 922873

Abstract: The present study examined performance in Theory of Mind (ToM) in a group of 31 Arabic-speaking verbal children (7-12 years-old) with autism spectrum disorder (ASD), in comparison with neurotypical controls (NT) matched for age and for cognitive ... ...

Abstract	The present study examined performance in Theory of Mind (ToM) in a group of 31 Arabic-speaking verbal children (7-12 years-old) with autism spectrum disorder (ASD), in comparison with neurotypical controls (NT) matched for age and for cognitive abilities. An innovative task in a digital format named "The Tunisian Social Situations Instrument" (TSSI) was used and allowed us to study four different subdomains of ToM: attribution of intention and epistemic ToM (cognitive ToM), affective ToM, and detection of faux pas (advanced ToM). Our study showed impairments in ToM in children with ASD, similar to those reported in the literature. Our findings additionally suggested that affective and advanced ToM, specifically the detection of faux pas, might be more challenging for ASD children than other components of ToM. Future studies with larger number of children may lead us to specify which subdomains are the most impaired in order to develop specific tools targeting these specific impairments.
Language	English
Publishing date	2022-11-17
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564218-2
ISSN	1664-0640
ISSN	1664-0640
DOI	10.3389/fpsyt.2022.922873
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Article: Validation of the Tunisian Test for Facial Emotions Recognition: Study in Children From 7 to 12 Years Old.

Taamallah, Amal / Halayem, Soumeyya / Rajhi, Olfa / Ghazzai, Malek / Moussa, Mohamed / Touati, Maissa / Ayadi, Houda Ben Yahia / Ouanes, Sami / Abbes, Zeineb S / Hajri, Melek / Jelili, Selima / Fakhfakh, Radhouane / Bouden, Asma

Frontiers in psychology

2021 Volume 12, Page(s) 643749

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2021-11-22
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2563826-9
ISSN	1664-1078
ISSN	1664-1078
DOI	10.3389/fpsyg.2021.643749
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Article: Validation of the Tunisian Empathy Scale for Children (TESC) in General Population and Children With Autism Spectrum Disorder.

Ben Youssef, Hela / Halayem, Soumeyya / Ghazzai, Malek / Jelili, Selima / Ben Mansour, Hager / Rajhi, Olfa / Taamallah, Amal / Ennaifer, Selima / Hajri, Malek / Abbes, Zeineb Salma / Fakhfakh, Radhouane / Nabli, Ahmed / Bouden, Asma

Frontiers in psychiatry

2022 Volume 13, Page(s) 903966

Abstract: Background: Several empathy assessment tests have been proposed worldwide but none of them took into account cultural variations that seem to affect empathic manifestations. The aim of this study was to create and validate an empathy assessment ... ...

Abstract	Background: Several empathy assessment tests have been proposed worldwide but none of them took into account cultural variations that seem to affect empathic manifestations. The aim of this study was to create and validate an empathy assessment questionnaire for school-aged Tunisian children entitled "Tunisian Empathy Scale for Children" (TESC). Methods: An evaluative cross-sectional study was conducted. The questionnaire was administered to parents of 197 neuro-typical children and 31 children with autism without associated intellectual deficits, aged between 7 and 12 years. Validation steps included: face validity, content validity, construct validity, and reliability study. A ROC curve analysis was used to investigate the diagnostic performance of the TESC. Results: Face validity was verified with an expert panel. Content validity was examined, and 11 items were removed as irrelevant or not assessable by parents. Exploratory factor analysis extracted four domains that explained 43% of the total variance. All these domains were significantly correlated with the total score ( Conclusion: A 15-item questionnaire assessing empathy in a multidimensional and culturally adapted way was obtained. The psychometric qualities of the TESC were satisfactory.
Language	English
Publishing date	2022-07-18
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564218-2
ISSN	1664-0640
ISSN	1664-0640
DOI	10.3389/fpsyt.2022.903966
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Article: The Cognitive Remediation Therapy Program Among Children with ADHD: Tunisian experience.

Hamza, Meriem / Abbes, Zeineb / Ben Yahyia, Houda / Fakhfekh, Radhouane / Amado, Isabelle / Bouden, Asma

La Tunisie medicale

2018 Volume 96, Issue 1, Page(s) 30–35

Abstract: Background: Attention-Deficit Hyperactivity Disorder (ADHD) is associated with neuropsychological deficits including executive and attentional impairments. The cognitive remediation therapy is a new promising technique designed to improve the ... ...

Abstract	Background: Attention-Deficit Hyperactivity Disorder (ADHD) is associated with neuropsychological deficits including executive and attentional impairments. The cognitive remediation therapy is a new promising technique designed to improve the neurocognitive abilities damaged in ADHD. Aim: Adapt and apply the cognitive remediation program CRT (Cognitive Remediation Therapy) for children and adolescents with ADHD and to evaluate its effectiveness on attentional and executive abilities. Methods: Children and adolescents with ADHD, diagnosed using the K-SADS-PL questionnaire was involved in the study. The CRT program was administered for an average period of fourteen weeks with a rate of one session per week of 40 minutes each. The Attentional Network Test was administered prior to the intervention and one week after. Results: Of the 30 patients included, 14 had reached the end of the program. Among them, nine patients passed the attentional test post CRT, thus constituting our final sample. Their average age was 9 years. The mean number of sessions performed was 14.5. Post CRT, the mean of patient's response time was found to be shorter (p=0,004) and the frequency of omissions errors was also lesser than that found at the initial assessment. Patients also committed fewer errors in incongruent situations in post program, with a significant improvement of the conflict effect (p= 0.009) signing a better executive control. Conclusions: Cognitive remediation is a promising new modality in the treatment of ADHD. Further research is needed to better document its effects and the optimal conditions required for setting it up.
MeSH term(s)	Adolescent ; Attention/physiology ; Attention Deficit Disorder with Hyperactivity/epidemiology ; Attention Deficit Disorder with Hyperactivity/psychology ; Attention Deficit Disorder with Hyperactivity/therapy ; Child ; Cognitive Remediation/methods ; Executive Function/physiology ; Female ; Humans ; Male ; Neuropsychological Tests ; Preliminary Data ; Psychology, Adolescent ; Treatment Outcome ; Tunisia/epidemiology
Language	English
Publishing date	2018-10-15
Publishing country	Tunisia
Document type	Clinical Trial ; Journal Article
ZDB-ID	128627-4
ISSN	0041-4131
ISSN	0041-4131
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Article: Impaired Recognition of Static and Dynamic Facial Emotions in Children With Autism Spectrum Disorder Using Stimuli of Varying Intensities, Different Genders, and Age Ranges Faces.

Jelili, Selima / Halayem, Soumeyya / Taamallah, Amal / Ennaifer, Selima / Rajhi, Olfa / Moussa, Mohamed / Ghazzei, Melek / Nabli, Ahmed / Ouanes, Sami / Abbes, Zeineb / Hajri, Malek / Fakhfakh, Radhouane / Bouden, Asma

Frontiers in psychiatry

2021 Volume 12, Page(s) 693310

Abstract: A multitude of research on facial emotion recognition (FER) in Autism Spectrum Disorders (ASD) have been published since several years. However, these studies have mainly used static high intensity stimuli, including adult and/or children facial emotions. ...

Abstract	A multitude of research on facial emotion recognition (FER) in Autism Spectrum Disorders (ASD) have been published since several years. However, these studies have mainly used static high intensity stimuli, including adult and/or children facial emotions. This current study investigated FER in children with ASD using an innovative task, composed of a combination of static (114 pictures) and dynamic (36 videos) subtests, including children, adolescent, and adult male and female faces, with high, medium, and low intensity of basic facial emotions, and neutral expression. The ASD group consisted of 45 Tunisian verbal children, and the control group consisted of 117 tunisian typically developing children. Both groups were aged 7-12 years. After adjusting for sex, age, mental age, and school grade, the ASD group scored lower than controls on all tests except for the recognition of happiness and fear in the static subtest, and the recognition of happiness, fear, and sadness in the dynamic subtest (
Language	English
Publishing date	2021-08-20
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564218-2
ISSN	1664-0640
ISSN	1664-0640
DOI	10.3389/fpsyt.2021.693310
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Article: Cognitive remediation therapy in autism spectrum disorder: Tunisian experience.

Hajri, Malek / Abbes, Zeineb / Ben Yahia, Houda / Boudali, Mariem / Bouden, Asma / Mrabet, Ali / Amado, Isabelle

La Tunisie medicale

2019 Volume 97, Issue 6, Page(s) 795–801

Abstract: Background: Cognitive dysfunctions associated with Autism spectrum disorder (ASD) are nowadays highlighted. These cognitive impairments include mainly executive dysfunctioning and are linked with academic difficulties, thus representing one of the ... ...

Abstract	Background: Cognitive dysfunctions associated with Autism spectrum disorder (ASD) are nowadays highlighted. These cognitive impairments include mainly executive dysfunctioning and are linked with academic difficulties, thus representing one of the treatment targets. Cognitive remediation therapy (CRT) is a new promising program aiming to remediate cognitive impairments by targeting executive functions. It attempts to teach information processing strategies through guided mental exercises. Aim: To assess the effectiveness of the cognitive remediation program CRT (Cognitive Remediation Therapy) on executive abilities and school results, in children and adolescents with ASD. Methods: Cross-sectional study involving children and adolescents with ASD according to DSM-5. The CRT program was conducted individually at the rate of one session per week of 45 minutes each. Outcome measures were intellectual abilities, cognitive flexibility, working memory and school performance. Results: Of the 25/24 patients included, 16 had reached the end of the program. Their average age was 10.87 years. The mean number of sessions performed was 22.38. After completion of CRT, patients showed significant improvement on intellectual abilities (p<10-3), phonemic fluency (p=0.032), « animal » category of semantic fluency (p=0.045), working memory (p=0.001 for forward digit-span and p=0.006 for backward digit span) and school results (p=0.001). Patients made more repetitive and intrusive errors in semantic fluency with significant increase in the "clothes" semantic category (p=0.019). Conclusion: Cognitive remediation enhances cognition directly and positively acts on clinical course. It appears to be a relevant new method in the management of ASD. Yet, further research is required in order to confirm the efficiency of this treatment and to better define its optimal settings.
MeSH term(s)	Adolescent ; Autism Spectrum Disorder/psychology ; Autism Spectrum Disorder/therapy ; Child ; Cognition/physiology ; Cognitive Remediation/methods ; Cross-Sectional Studies ; Executive Function/physiology ; Humans ; Treatment Outcome ; Tunisia
Language	English
Publishing date	2019-12-23
Publishing country	Tunisia
Document type	Journal Article
ZDB-ID	128627-4
ISSN	0041-4131
ISSN	0041-4131
Database	MEDical Literature Analysis and Retrieval System OnLINE

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