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  1. Article ; Online: Re: Michael Eppler, Conner Ganjavi, Lorenzo Storino Ramacciotti, et al. Awareness and Use of ChatGPT and Large Language Models: A Prospective Cross-sectional Global Survey in Urology. Eur Urol 2024;85:146-53.

    Cardona Ortegón, José David / Serrano, Samuel / Romero Cortes, Daniel

    European urology

    2024  

    Language English
    Publishing date 2024-04-20
    Publishing country Switzerland
    Document type Letter
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2024.02.033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Uninterrupted Oral Anticoagulation During Catheter Ablation of Ventricular Tachycardia: Is the Riskier Option the Safest?

    Romero, Jorge E / Goldhaber, Samuel Z

    JACC. Clinical electrophysiology

    2022  Volume 8, Issue 6, Page(s) 749–753

    MeSH term(s) Anticoagulants/adverse effects ; Catheter Ablation/adverse effects ; Humans ; Tachycardia, Ventricular/surgery
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2022-04-27
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2846739-5
    ISSN 2405-5018 ; 2405-500X ; 2405-500X
    ISSN (online) 2405-5018 ; 2405-500X
    ISSN 2405-500X
    DOI 10.1016/j.jacep.2022.04.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Imaging of Small Artery Vasculitis.

    Hamam, Omar / Cartmell, Samuel C / Romero, Javier M

    Neuroimaging clinics of North America

    2023  Volume 34, Issue 1, Page(s) 67–79

    Abstract: Small artery vasculitis of the CNS is a rare and serious condition characterized by the inflammation of blood vessels within the brain and spinal cord. There are two groups of small artery vasculitis determined by the presence or absence of ... ...

    Abstract Small artery vasculitis of the CNS is a rare and serious condition characterized by the inflammation of blood vessels within the brain and spinal cord. There are two groups of small artery vasculitis determined by the presence or absence of immunoglobulin complex deposition in the vessel wall. The former includes anti-glomerular basement membrane disease, cryoglobulinemic vasculitis, and IgA vasculitis. Absence of immune complex deposition is associated with anti-neutrophil cytoplasmic antibody (ANCA) and includes microscopic polyangiitis, granulomatosis with polyangiitis, eosinophilic granulomatosis with polyangiitis, and primary angiitis of the CNS. These conditions present a diagnostic challenge in which imaging plays a crucial role.
    MeSH term(s) Humans ; Granulomatosis with Polyangiitis/diagnostic imaging ; Churg-Strauss Syndrome/diagnosis ; Microscopic Polyangiitis/diagnosis ; Arteries ; Antibodies, Antineutrophil Cytoplasmic
    Chemical Substances Antibodies, Antineutrophil Cytoplasmic
    Language English
    Publishing date 2023-08-21
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1314594-0
    ISSN 1557-9867 ; 1052-5149
    ISSN (online) 1557-9867
    ISSN 1052-5149
    DOI 10.1016/j.nic.2023.07.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Depression, Cardiovascular Disease, and Female Gender: An Underestimated Triad.

    Avila, Walkiria Samuel / Rivera, Maria Alayde Mendonça / Rivera, Ivan Romero

    Arquivos brasileiros de cardiologia

    2023  Volume 120, Issue 7, Page(s) e20220858

    Title translation Depressão, Doença Cardiovascular e Sexo Feminino: Uma Tríade Subestimada.
    MeSH term(s) Humans ; Female ; Depression ; Cardiovascular Diseases/etiology
    Language Portuguese
    Publishing date 2023-07-17
    Publishing country Brazil
    Document type Letter
    ZDB-ID 730261-7
    ISSN 1678-4170 ; 0066-782X
    ISSN (online) 1678-4170
    ISSN 0066-782X
    DOI 10.36660/abc.20220858
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Development, characterization, and evaluation of a simple polymicrobial colony biofilm model for testing of antimicrobial wound dressings.

    Robertson, Shaun N / Romero, Manuel / Fenn, Samuel / Kohler Riedi, Petra L / Cámara, Miguel

    Journal of applied microbiology

    2024  Volume 135, Issue 3

    Abstract: Chronic wound infections are generally of polymicrobial nature with aerobic and anaerobic bacteria, as well as fungi frequently observed in them. Wound treatment involves a series of steps, including debridement of the wound, flushing, and often the use ... ...

    Abstract Chronic wound infections are generally of polymicrobial nature with aerobic and anaerobic bacteria, as well as fungi frequently observed in them. Wound treatment involves a series of steps, including debridement of the wound, flushing, and often the use of multiple wound dressings many of which are antimicrobial. Yet, many wound dressings are tested versus single species of planktonic microbes, which fails to mirror the real-life presence of biofilms.
    Aims: Simple biofilm models are the first step to testing of any antimicrobial and wound dressing; therefore, the aim of this study was to develop and validate a simple polymicrobial colony biofilm wound model comprised of Pseudomonas aeruginosa, Staphylococcus aureus, and Candida albicans on RPMI-1640 agar. The model was then used to evaluate the topical disinfectant chlorohexidine and four commercially available wound dressings using the polymicrobial model. The model used was as a starting point to mimic debridement in clinical care of wounds and the effectiveness of wound dressings evaluated afterwards.
    Methods and results: Planktonic assessment using AATCC100-2004 demonstrated that all antimicrobial wound dressings reduced the planktonic microbial burden below the limit of detection; however, when challenged with polymicrobial colony biofilms, silver wound dressings showed limited effectiveness (1-2 log CFU reductions). In contrast, a single iodine releasing wound dressing showed potent antibiofilm activity reducing all species CFUs below the limit of detection (>6-10 log) depending on the species. A disrupted biofilm model challenge was performed to represent the debridement of a wound and wound silver-based wound dressings were found to be marginally more effective than in whole colony biofilm challenges while the iodine containing wound dressing reduced microbial recovery below the limit of detection.
    Conclusions: In this model, silver dressings were ineffective versus the whole colony biofilms but showed some recovery of activity versus the disrupted colony biofilm. The iodine wound dressing reduced the viability of all species below the level of detection. This suggests that mode of action of wound dressing should be considered for the type of biofilm challenge as should the clinical use, e.g. debridement.
    MeSH term(s) Humans ; Silver ; Anti-Infective Agents/pharmacology ; Bandages ; Iodine/pharmacology ; Iodine/therapeutic use ; Biofilms ; Wound Infection/prevention & control ; Wound Infection/drug therapy ; Pseudomonas aeruginosa
    Chemical Substances Silver (3M4G523W1G) ; Anti-Infective Agents ; Iodine (9679TC07X4)
    Language English
    Publishing date 2024-02-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 1358023-1
    ISSN 1365-2672 ; 1364-5072
    ISSN (online) 1365-2672
    ISSN 1364-5072
    DOI 10.1093/jambio/lxae042
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Neurochagas in post-heart transplant: clinical and epidemiological analysis of this entity based on a series of cases.

    Espinoza Romero, Cristhian / Catto De Marchi, Daniel / Marcondes-Braga, Fabiana G / Mangini, Sandrigo / Samuel Avila, Mônica / Bacal, Fernando

    Revista espanola de cardiologia (English ed.)

    2023  Volume 77, Issue 3, Page(s) 269–272

    MeSH term(s) Humans ; Heart Transplantation ; Heart ; Retrospective Studies
    Language Spanish
    Publishing date 2023-10-26
    Publishing country Spain
    Document type Case Reports
    ZDB-ID 2592481-3
    ISSN 1885-5857 ; 1885-5857
    ISSN (online) 1885-5857
    ISSN 1885-5857
    DOI 10.1016/j.rec.2023.09.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Outpatient treatment of COVID-19: an experience with 552 cases in Mexico.

    Romero-Cabello, Raúl / Romero-Feregrino, Raúl / Romero-Feregrino, Rodrigo / Muñoz-Cordero, Berenice / Sevilla-Fuentes, Samuel

    Journal of infection in developing countries

    2023  Volume 17, Issue 3, Page(s) 311–318

    Abstract: Introduction: The impact of the coronavirus disease 2019 (COVID-19) pandemic has globally challenged health services, especially because when the pandemic first reached Mexico, in February 2020, there was no known effective and safe treatment. A ... ...

    Abstract Introduction: The impact of the coronavirus disease 2019 (COVID-19) pandemic has globally challenged health services, especially because when the pandemic first reached Mexico, in February 2020, there was no known effective and safe treatment. A treatment scheme was offered by the Institute for the Integral Development of Health (IDISA) in Mexico City from March 2020 to August 2021 when there were many patients with COVID-19. This report summarizes the experience managing COVID-19 with this scheme.
    Materials and methods: This is a descriptive, retrolective study. The data was obtained from the case files of the patients who attended the IDISA from March 2020 to August 2021 with COVID-19. All the cases were treated with the scheme consisting of nitazoxanide, azithromycin, and prednisone. Various laboratory blood tests and chest computerized tomography scan were done. When indicated, supplementary oxygen, and another specific treatment were used. A standardized clinical recording was conducted for 20 days based on symptoms and systemic symptoms.
    Results: Based on the World Health Organization criteria, the patients were classified according to the disease severity: 170 mild, 70 moderate, and 312 severe cases. The outcome was the discharge of 533 patients after their recovery, 16 were excluded from the study, and 6 died.
    Conclusions: The use of nitazoxanide, azithromycin, and prednisone proved to be effective as it resulted in improvement of symptoms and in successful outcomes for the management of COVID-19 outpatients.
    MeSH term(s) Humans ; COVID-19 ; SARS-CoV-2 ; Outpatients ; Prednisone ; Mexico/epidemiology ; Azithromycin/therapeutic use ; Treatment Outcome
    Chemical Substances nitazoxanide (SOA12P041N) ; Prednisone (VB0R961HZT) ; Azithromycin (83905-01-5)
    Language English
    Publishing date 2023-03-31
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2394024-4
    ISSN 1972-2680 ; 2036-6590
    ISSN (online) 1972-2680
    ISSN 2036-6590
    DOI 10.3855/jidc.16982
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Celebrating a decade of the

    Romero, Pedro J / Gulley, James L / Hwu, Patrick / Dean, Mary / Million-Weaver, Samuel

    Journal for immunotherapy of cancer

    2022  Volume 10, Issue 5

    MeSH term(s) Humans ; Immunologic Factors ; Immunotherapy ; Neoplasms/therapy
    Chemical Substances Immunologic Factors
    Language English
    Publishing date 2022-05-27
    Publishing country England
    Document type Editorial
    ZDB-ID 2719863-7
    ISSN 2051-1426 ; 2051-1426
    ISSN (online) 2051-1426
    ISSN 2051-1426
    DOI 10.1136/jitc-2022-005207
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Low-Cost EEG Multi-Subject Recording Platform for the Assessment of Students' Attention and the Estimation of Academic Performance in Secondary School.

    Fuentes-Martinez, Victor Juan / Romero, Samuel / Lopez-Gordo, Miguel Angel / Minguillon, Jesus / Rodríguez-Álvarez, Manuel

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 23

    Abstract: The level of student attention in class greatly affects their academic performance. Teachers typically rely on visual inspection to react to students' attention in time, but this subjective method leads to inconsistencies across classes. Online education ...

    Abstract The level of student attention in class greatly affects their academic performance. Teachers typically rely on visual inspection to react to students' attention in time, but this subjective method leads to inconsistencies across classes. Online education exacerbates the issue as students can turn off cameras and microphones to keep their own privacy. To address this, we present a novel, low-cost EEG-based platform for assessing students' attention and estimating their academic performance. In a study involving 34 secondary school students (aged 14 to 16), participants watched an academic video and answered evaluation questions while their EEG activity was recorded using a commercial headset. The results demonstrate a significant correlation (0.53,
    MeSH term(s) Humans ; Students ; Schools ; Academic Performance ; Learning ; Electroencephalography
    Language English
    Publishing date 2023-11-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23239361
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  10. Article ; Online: Drug efflux and lipid A modification by 4-L-aminoarabinose are key mechanisms of polymyxin B resistance in the sepsis pathogen Enterobacter bugandensis.

    García-Romero, Inmaculada / Srivastava, Mugdha / Monjarás-Feria, Julia / Korankye, Samuel O / MacDonald, Lewis / Scott, Nichollas E / Valvano, Miguel A

    Journal of global antimicrobial resistance

    2024  Volume 37, Page(s) 108–121

    Abstract: Objectives: A concern with the ESKAPE pathogen, Enterobacter bugandensis, and other species of the Enterobacter cloacae complex, is the frequent appearance of multidrug resistance against last-resort antibiotics, such as polymyxins.: Methods: Here, ... ...

    Abstract Objectives: A concern with the ESKAPE pathogen, Enterobacter bugandensis, and other species of the Enterobacter cloacae complex, is the frequent appearance of multidrug resistance against last-resort antibiotics, such as polymyxins.
    Methods: Here, we investigated the responses to polymyxin B (PMB) in two PMB-resistant E. bugandensis clinical isolates by global transcriptomics and deletion mutagenesis.
    Results: In both isolates, the genes of the CrrAB-regulated operon, including crrC and kexD, displayed the highest levels of upregulation in response to PMB. ∆crrC and ∆kexD mutants became highly susceptible to PMB and lost the heteroresistant phenotype. Conversely, heterologous expression of CrrC and KexD proteins increased PMB resistance in a sensitive Enterobacter ludwigii clinical isolate and in the Escherichia coli K12 strain, W3110. The efflux pump, AcrABTolC, and the two component regulators, PhoPQ and CrrAB, also contributed to PMB resistance and heteroresistance. Additionally, the lipid A modification with 4-L-aminoarabinose (L-Ara4N), mediated by the arnBCADTEF operon, was critical to determine PMB resistance. Biochemical experiments, supported by mass spectrometry and structural modelling, indicated that CrrC is an inner membrane protein that interacts with the membrane domain of the KexD pump. Similar interactions were modeled for AcrB and AcrD efflux pumps.
    Conclusion: Our results support a model where drug efflux potentiated by CrrC interaction with membrane domains of major efflux pumps combined with resistance to PMB entry by the L-Ara4N lipid A modification, under the control of PhoPQ and CrrAB, confers the bacterium high-level resistance and heteroresistance to PMB.
    Language English
    Publishing date 2024-03-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2710046-7
    ISSN 2213-7173 ; 2213-7173
    ISSN (online) 2213-7173
    ISSN 2213-7173
    DOI 10.1016/j.jgar.2024.03.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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