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  1. Book ; Online: Evidence-based Advance and Management of Adverse Events of Immunotherapy for Cancer

    Zhang, Yonggang / Ma, Xuelei / Zhou, Shuang / Zhou, Shuang

    2020  

    Keywords Science: general issues ; Pharmacology ; Evidence-based ; immunotherapy ; cancer ; adverse event ; management
    Size 1 electronic resource (207 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021230675
    ISBN 9782889662470 ; 2889662470
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Carbonate Ester-Based Electrolyte Enabling Rechargeable Zn Battery to Achieve High Voltage and High Zn Utilization.

    Zhou, Kang / Liu, Gaopan / Yu, Xiaomeng / Li, Zhi / Wang, Yonggang

    Journal of the American Chemical Society

    2024  Volume 146, Issue 13, Page(s) 9455–9464

    Abstract: Owing to the high ... ...

    Abstract Owing to the high H
    Language English
    Publishing date 2024-03-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.4c02150
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 4' 55/32: Show issues
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  3. Article ; Online: Ce

    Zhou, Jinru / Wen, Ting / Wang, Yonggang / Cong, Rihong / Yang, Tao

    Inorganic chemistry

    2023  Volume 62, Issue 51, Page(s) 21138–21146

    Abstract: The performance of ... ...

    Abstract The performance of Ce
    Language English
    Publishing date 2023-12-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1484438-2
    ISSN 1520-510X ; 0020-1669
    ISSN (online) 1520-510X
    ISSN 0020-1669
    DOI 10.1021/acs.inorgchem.3c03046
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The role of receptors in the cross-species spread of coronaviruses infecting humans and pigs.

    Zhuang, Jie / Yan, Zhiwei / Zhou, Tiezhong / Li, Yonggang / Wang, Huinuan

    Archives of virology

    2024  Volume 169, Issue 2, Page(s) 35

    Abstract: The pandemic caused by SARS-CoV-2, which has proven capable of infecting over 30 animal species, highlights the critical need for understanding the mechanisms of cross-species transmission and the emergence of novel coronavirus strains. The recent ... ...

    Abstract The pandemic caused by SARS-CoV-2, which has proven capable of infecting over 30 animal species, highlights the critical need for understanding the mechanisms of cross-species transmission and the emergence of novel coronavirus strains. The recent discovery of CCoV-HuPn-2018, a recombinant alphacoronavirus from canines and felines that can infect humans, along with evidence of SARS-CoV-2 infection in pig cells, underscores the potential for coronaviruses to overcome species barriers. This review investigates the origins and cross-species transmission of both human and porcine coronaviruses, with a specific emphasis on the instrumental role receptors play in this process.
    MeSH term(s) Humans ; Animals ; Cats ; Dogs ; Swine ; Cat Diseases ; Dog Diseases ; COVID-19 ; Pandemics ; SARS-CoV-2
    Language English
    Publishing date 2024-01-24
    Publishing country Austria
    Document type Journal Article ; Review
    ZDB-ID 7491-3
    ISSN 1432-8798 ; 0304-8608
    ISSN (online) 1432-8798
    ISSN 0304-8608
    DOI 10.1007/s00705-023-05956-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.110: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Bioinformatics analysis and validation of CSRNP1 as a key prognostic gene in non-small cell lung cancer.

    Xu, Zhongneng / Zhou, Hao / Luo, Yonggang / Li, Nunu / Chen, Sheng

    Heliyon

    2024  Volume 10, Issue 7, Page(s) e28412

    Abstract: Cysteine and serine-rich nuclear protein 1 (CSRNP1) has shown prognostic significance in various cancers, but its role in non-small cell lung cancer (NSCLC) remains elusive. We investigated CSRNP1 expression in NSCLC cases using bioinformatics tools from ...

    Abstract Cysteine and serine-rich nuclear protein 1 (CSRNP1) has shown prognostic significance in various cancers, but its role in non-small cell lung cancer (NSCLC) remains elusive. We investigated CSRNP1 expression in NSCLC cases using bioinformatics tools from the GEO public repository and validated our findings through RT-qPCR in tumor and adjacent normal tissues. KEGG and GO enrichment analyses were employed to unveil the significant deregulation in signaling pathways. Additionally, clinical significance of CSRNP1 in NSCLC was determined through receiver operating curve (ROC) analysis, and its impact on survival was assessed using Kaplan-Meier analysis. To explore the functional impact of CSRNP1, we silenced its expression in NSCLC cells and assessed the effects on cell viability, migration, and invasion using MTT, Transwell, and wound-healing assays, respectively. Additionally, we investigated the influence of CSRNP1 silencing on the phosphorylation patterns of critical signaling proteins such as p53,
    Language English
    Publishing date 2024-03-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e28412
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Integrated Optimal Control for Electrolyte Temperature With Temporal Causal Network and Reinforcement Learning.

    Liu, Tianhao / Yang, Chunhua / Zhou, Can / Li, Yonggang / Sun, Bei

    IEEE transactions on neural networks and learning systems

    2024  Volume 35, Issue 5, Page(s) 5929–5941

    Abstract: The electrowinning process is a critical operation in nonferrous hydrometallurgy and consumes large quantities of power consumption. Current efficiency is an important process index related to power consumption, and it is vital to operate the electrolyte ...

    Abstract The electrowinning process is a critical operation in nonferrous hydrometallurgy and consumes large quantities of power consumption. Current efficiency is an important process index related to power consumption, and it is vital to operate the electrolyte temperature close to the optimum point to ensure high current efficiency. However, the optimal control of electrolyte temperature faces the following challenges. First, the temporal causal relationship between process variables and current efficiency makes it difficult to estimate the current efficiency accurately and set the optimal electrolyte temperature. Second, the substantial fluctuation of influencing variables of electrolyte temperature leads to difficulty in maintaining the electrolyte temperature close to the optimum point. Third, due to the complex mechanism, building a dynamic electrowinning process model is intractable. Hence, it is a problem of index optimal control in the multivariable fluctuation scenario without process modeling. To get around this issue, an integrated optimal control method based on temporal causal network and reinforcement learning (RL) is proposed. First, the working conditions are divided and the temporal causal network is used to estimate current efficiency accurately to solve the optimal electrolyte temperature under multiple working conditions. Then, an RL controller is established under each working condition, and the optimal electrolyte temperature is placed into the controller's reward function to assist in control strategy learning. An experiment case study of the zinc electrowinning process is provided to verify the effectiveness of the proposed method and to show that it can stabilize the electrolyte temperature within the optimal range without modeling.
    Language English
    Publishing date 2024-05-02
    Publishing country United States
    Document type Journal Article
    ISSN 2162-2388
    ISSN (online) 2162-2388
    DOI 10.1109/TNNLS.2023.3278729
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Trade-off of leaf-scale resource-use efficiencies along the vertical canopy of the subtropical forest.

    Zhuang, Jie / Chi, Yonggang / Wang, Yonglin / Zhou, Lei

    Journal of plant physiology

    2023  Volume 286, Page(s) 154004

    Abstract: Leaf resource-use efficiencies are key indicators of plant adaptability to climate change, as they depend on both photosynthetic carbon assimilation and available resources. However, accurately quantifying the response of the coupled carbon and water ... ...

    Abstract Leaf resource-use efficiencies are key indicators of plant adaptability to climate change, as they depend on both photosynthetic carbon assimilation and available resources. However, accurately quantifying the response of the coupled carbon and water cycles is challenging due to the canopy vertical variability in resource-use efficiencies, which introduces greater uncertainty into the calculations. Here we experimented to ascertain the vertical variations of leaf resource-use efficiencies along three canopy gradients of coniferous (Pinus elliottii Engelmann.) and broad-leaved (Schima Superba Gardn & Champ.) forests over one year in the subtropical region of China. The efficiency of water (WUE), and nitrogen (NUE) showed higher values in the top canopy level for the two species. The maximum efficiency of light (LUE) occurred in the bottom canopy level for both species. The impact of photosynthetic photon flux density (PPFD), leaf temperature (T
    MeSH term(s) Forests ; Plant Leaves ; Nitrogen ; Trees ; Carbon ; Pinus ; Water
    Chemical Substances Nitrogen (N762921K75) ; Carbon (7440-44-0) ; Water (059QF0KO0R)
    Language English
    Publishing date 2023-05-12
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 283647-6
    ISSN 1618-1328 ; 0176-1617
    ISSN (online) 1618-1328
    ISSN 0176-1617
    DOI 10.1016/j.jplph.2023.154004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 46/302: Show issues

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  8. Article ; Online: Spring phenology rather than climate dominates the trends in peak of growing season in the Northern Hemisphere.

    Huang, Zhi / Zhou, Lei / Chi, Yonggang

    Global change biology

    2023  Volume 29, Issue 16, Page(s) 4543–4555

    Abstract: Shifts in plant phenology regulate ecosystem structure and function, which feeds back to the climate system. However, drivers for the peak of growing season (POS) in seasonal dynamics of terrestrial ecosystems remain unclear. Here, spatial-temporal ... ...

    Abstract Shifts in plant phenology regulate ecosystem structure and function, which feeds back to the climate system. However, drivers for the peak of growing season (POS) in seasonal dynamics of terrestrial ecosystems remain unclear. Here, spatial-temporal patterns of POS dynamics were analyzed by solar-induced chlorophyll fluorescence (SIF) and vegetation index in the Northern Hemisphere over the past two decades from 2001 to 2020. Overall, a slow advanced POS was observed in the Northern Hemisphere, while a delayed POS distributed mainly in northeastern North America. Trends of POS were driven by the start of growing season (SOS) rather than pre-POS climate both at hemisphere and biome scale. The effect of SOS on the trends in POS was the strongest in shrublands while the weakest in evergreen broad-leaved forest. These findings highlight the crucial role of biological rhythms rather than climatic factors in exploring seasonal carbon dynamics and global carbon balance.
    MeSH term(s) Seasons ; Ecosystem ; Climate ; Forests ; Climate Change ; Carbon
    Chemical Substances Carbon (7440-44-0)
    Language English
    Publishing date 2023-05-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 1281439-8
    ISSN 1365-2486 ; 1354-1013
    ISSN (online) 1365-2486
    ISSN 1354-1013
    DOI 10.1111/gcb.16758
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 6338: Show issues

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  9. Article ; Online: Boosting Zn Anode Utilization by Trace Iodine Ions in Organic-Water Hybrid Electrolytes through Formation of Anion-rich Adsorbing Layers.

    Zhou, Kang / Li, Zhi / Qiu, Xuan / Yu, Zhuo / Wang, Yonggang

    Angewandte Chemie (International ed. in English)

    2023  Volume 62, Issue 39, Page(s) e202309594

    Abstract: Aqueous Zn batteries are attracting extensive attentions, but their application is still hindered by ... ...

    Abstract Aqueous Zn batteries are attracting extensive attentions, but their application is still hindered by H
    Language English
    Publishing date 2023-08-21
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202309594
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Field Test Study on the Bearing Capacity of Extra-Long PHC Pipe Piles under Dynamic and Static Loads

    Yonggang Xiao / Xiaomin Liu / Junlong Zhou / Liwei Song

    Sustainability, Vol 15, Iss 5161, p

    2023  Volume 5161

    Abstract: Pretensioned prestressed high strength concrete (PHC) pipe piles are widely used in various engineering foundations, which have the advantages of high single pile bearing capacity, strong adaptability to geological conditions and high degree of ... ...

    Abstract Pretensioned prestressed high strength concrete (PHC) pipe piles are widely used in various engineering foundations, which have the advantages of high single pile bearing capacity, strong adaptability to geological conditions and high degree of construction mechanization. In order to study the vertical compressive bearing performance and settlement characteristics of ultra-long PHC pipe piles, high strain dynamic detections and static load tests were carried out on four PHC piles with a diameter of 0.9 m on site. It can be seen from the field test that the bearing capacity of the prefabricated pipe piles was time-dependent. By the end of the dynamic test, the bearing capacity of each test pile increased by 27% to 66%. The static load test also verified the rationality of the value of the restitution coefficient. Therefore, the final bearing capacity of the pile foundation can be predicted by using the high strain initial driving results and the restitution coefficient, which can reduce the repeated driving process, effectively save the cost and improve the engineering efficiency. Under 2.1 times the design load, the change range of the pile concrete modulus is from 37.5 GPa to 52 GPa, the change range of the pile side friction resistance is from 0 kPa to 97 kPa and the change range of the pile end to pile bottom load ratio is from 0% to 7.54%. During the test, the shaft friction and end bearing of the lower part of the piles were not fully mobilized. The shaft friction resistance, the end resistance and the movement behavior of the pile top and the end of the piles can provide parameter references for the subsequent design and construction of the piles.
    Keywords bearing capacity ; PHC pipe piles ; pile driving analyzer (PDA) ; static load tests ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 690
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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