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  1. Article ; Online: The two faces of pancreas tissue-resident macrophages.

    Saffern, Miriam / Merad, Miriam

    Nature reviews. Immunology

    2022  Volume 22, Issue 6, Page(s) 336

    MeSH term(s) Humans ; Macrophages ; Pancreas
    Language English
    Publishing date 2022-04-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2062776-2
    ISSN 1474-1741 ; 1474-1733
    ISSN (online) 1474-1741
    ISSN 1474-1733
    DOI 10.1038/s41577-022-00728-x
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  2. Article ; Online: Reflections from a mother scientist.

    Merad, Miriam

    Nature medicine

    2020  Volume 26, Issue 9, Page(s) 1316

    MeSH term(s) Female ; Humans ; Mothers ; Science
    Language English
    Publishing date 2020-08-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1220066-9
    ISSN 1546-170X ; 1078-8956
    ISSN (online) 1546-170X
    ISSN 1078-8956
    DOI 10.1038/s41591-020-1052-8
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  3. Article ; Online: Pathological sequelae of long-haul COVID.

    Mehandru, Saurabh / Merad, Miriam

    Nature immunology

    2022  Volume 23, Issue 2, Page(s) 194–202

    Abstract: The world continues to contend with successive waves of coronavirus disease 2019 (COVID-19), fueled by the emergence of viral variants. At the same time, persistent, prolonged and often debilitating sequelae are increasingly recognized in convalescent ... ...

    Abstract The world continues to contend with successive waves of coronavirus disease 2019 (COVID-19), fueled by the emergence of viral variants. At the same time, persistent, prolonged and often debilitating sequelae are increasingly recognized in convalescent individuals, named 'post-COVID-19 syndrome' or 'long-haul COVID'. Clinical symptomatology includes fatigue, malaise, dyspnea, defects in memory and concentration and a variety of neuropsychiatric syndromes as the major manifestations, and several organ systems can be involved. The underlying pathophysiological mechanisms are poorly understood at present. This Review details organ-specific sequelae of post-COVID-19 syndromes and examines the underlying pathophysiological mechanisms available so far, elaborating on persistent inflammation, induced autoimmunity and putative viral reservoirs. Finally, we propose diagnostic strategies to better understand this heterogeneous disorder that continues to afflict millions of people worldwide.
    MeSH term(s) COVID-19/complications ; COVID-19/immunology ; COVID-19/physiopathology ; COVID-19/virology ; Host-Pathogen Interactions ; Humans ; Prognosis ; SARS-CoV-2/immunology ; SARS-CoV-2/pathogenicity ; Symptom Assessment ; Time Factors ; Post-Acute COVID-19 Syndrome
    Language English
    Publishing date 2022-02-01
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2016987-5
    ISSN 1529-2916 ; 1529-2908
    ISSN (online) 1529-2916
    ISSN 1529-2908
    DOI 10.1038/s41590-021-01104-y
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  4. Article ; Online: Publisher Correction: Innate IL-13 licenses dermal type 2 dendritic cells for efficient T helper 2 cell responses.

    Mattiuz, Raphaël / Merad, Miriam

    Nature reviews. Immunology

    2021  Volume 21, Issue 5, Page(s) 336

    Language English
    Publishing date 2021-04-20
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2062776-2
    ISSN 1474-1741 ; 1474-1733
    ISSN (online) 1474-1741
    ISSN 1474-1733
    DOI 10.1038/s41577-021-00555-6
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  5. Article ; Online: Cooperation between the alveolar epithelium and lung-resident basophils shapes alveolar macrophages.

    Park, Matthew D / Merad, Miriam

    Nature reviews. Immunology

    2021  Volume 21, Issue 6, Page(s) 344

    Language English
    Publishing date 2021-04-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2062776-2
    ISSN 1474-1741 ; 1474-1733
    ISSN (online) 1474-1741
    ISSN 1474-1733
    DOI 10.1038/s41577-021-00561-8
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  6. Article ; Online: Innate IL-13 licenses dermal type 2 dendritic cells for efficient T helper 2 cell responses.

    Mattiuz, Raphaël / Merad, Miriam

    Nature reviews. Immunology

    2021  Volume 21, Issue 5, Page(s) 275

    Language English
    Publishing date 2021-04-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2062776-2
    ISSN 1474-1741 ; 1474-1733
    ISSN (online) 1474-1741
    ISSN 1474-1733
    DOI 10.1038/s41577-021-00552-9
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  7. Article ; Online: Expanding dendritic cell nomenclature in the single-cell era.

    Ginhoux, Florent / Guilliams, Martin / Merad, Miriam

    Nature reviews. Immunology

    2022  Volume 22, Issue 2, Page(s) 67–68

    MeSH term(s) Dendritic Cells ; Humans
    Language English
    Publishing date 2022-01-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2062776-2
    ISSN 1474-1741 ; 1474-1733
    ISSN (online) 1474-1741
    ISSN 1474-1733
    DOI 10.1038/s41577-022-00675-7
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  8. Article ; Online: Children and SARS-CoV-2.

    Bogunovic, Dusan / Merad, Miriam

    Cell host & microbe

    2021  Volume 29, Issue 7, Page(s) 1040–1042

    Abstract: A previously immune-naive world population is experiencing natural infection with SARS-CoV-2. Severe COVID-19 predominantly impacts adults, yet multisystem inflammatory disorder primarily impacts children. Herein, we discuss known clinical and biological ...

    Abstract A previously immune-naive world population is experiencing natural infection with SARS-CoV-2. Severe COVID-19 predominantly impacts adults, yet multisystem inflammatory disorder primarily impacts children. Herein, we discuss known clinical and biological features of SARS-CoV-2 in children and reflect on currently identified immune features and discuss what remains unknown.
    MeSH term(s) COVID-19/immunology ; COVID-19/physiopathology ; Child ; Hospitalization ; Humans ; Immunity ; SARS-CoV-2 ; Vaccination
    Language English
    Publishing date 2021-07-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2278004-X
    ISSN 1934-6069 ; 1931-3128
    ISSN (online) 1934-6069
    ISSN 1931-3128
    DOI 10.1016/j.chom.2021.06.015
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  9. Article ; Online: Highlights from a year in a pandemic.

    Merad, Miriam / Vabret, Nicolas

    The Journal of experimental medicine

    2021  Volume 218, Issue 5

    Abstract: COVID-19 has emerged as one of the worst pandemics in recent history and has exposed the weaknesses of healthcare systems worldwide. Here, we reflect on the lessons learned from a year in a pandemic. We discuss the extraordinary scientific advances made ... ...

    Abstract COVID-19 has emerged as one of the worst pandemics in recent history and has exposed the weaknesses of healthcare systems worldwide. Here, we reflect on the lessons learned from a year in a pandemic. We discuss the extraordinary scientific advances made in our understanding of a new disease, the failed and successful attempts to halt its progression, and the impact of the pandemic on the scientific discourse within the global community.
    MeSH term(s) Biomedical Research ; COVID-19/epidemiology ; COVID-19/metabolism ; COVID-19/pathology ; COVID-19/therapy ; Humans ; Pandemics ; SARS-CoV-2/metabolism
    Language English
    Publishing date 2021-03-23
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 218343-2
    ISSN 1540-9538 ; 0022-1007
    ISSN (online) 1540-9538
    ISSN 0022-1007
    DOI 10.1084/jem.20210220
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  10. Article ; Online: RNA vaccines: A transformational advance.

    Brown, Brian D / Fauci, Anthony S / Belkaid, Yasmine / Merad, Miriam

    Immunity

    2023  Volume 56, Issue 12, Page(s) 2665–2669

    Abstract: Vaccines have stemmed many infectious diseases, but when SARS-CoV-2 emerged, traditional vaccine development would not have been fast enough. This year's Nobel Prize in Physiology or Medicine recognizes work that enabled the rapid development of mRNA ... ...

    Abstract Vaccines have stemmed many infectious diseases, but when SARS-CoV-2 emerged, traditional vaccine development would not have been fast enough. This year's Nobel Prize in Physiology or Medicine recognizes work that enabled the rapid development of mRNA vaccines, which halted the COVID-19 pandemic. The feat was a product of basic biological insights coupled with technological innovations, which have transformed vaccine design.
    MeSH term(s) Humans ; mRNA Vaccines ; Pandemics/prevention & control ; COVID-19/prevention & control ; COVID-19 Vaccines/genetics ; Vaccines/genetics
    Chemical Substances mRNA Vaccines ; COVID-19 Vaccines ; Vaccines
    Language English
    Publishing date 2023-12-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1217235-2
    ISSN 1097-4180 ; 1074-7613
    ISSN (online) 1097-4180
    ISSN 1074-7613
    DOI 10.1016/j.immuni.2023.11.009
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