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  1. Article: [No title information]

    Jappe, Uta

    Aktuelle Ernährungsmedizin

    2023  Volume 48, Issue 03, Page(s) 195–208

    Abstract: Das Alpha-Gal-Syndrom umfasst eine um 3–12 Stunden verzögert einsetzende z.T. schwere Nahrungsmittelanaphylaxie. Diese Latenz kompliziert die Diagnosestellung ebenso wie die Tatsache, dass das auslösende Allergen ...

    Abstract Das Alpha-Gal-Syndrom umfasst eine um 3–12 Stunden verzögert einsetzende z.T. schwere Nahrungsmittelanaphylaxie. Diese Latenz kompliziert die Diagnosestellung ebenso wie die Tatsache, dass das auslösende Allergen ein Zucker ist, da proteinbasierte Testverfahren negativ bleiben können. Diese Arbeit beschreibt die Entdeckung dieser neuen Entität, ihre Ursachen, ihre Risiken und die relevante Diagnostik.
    Keywords Fleischallergie ; verzögerte Anaphylaxie ; Medikamentenallergie ; Milchallergie ; Einzelallergene ; kreuzreaktive Kohlenhydratepitope (CCD) ; zeckenübertragbare Erkrankung ; meat allergy ; delayed anaphylaxis ; single allergens ; cross-reactive carbohydrate determinants (CCD) ; tick-borne disease ; milk allergy, drug allergy
    Language German
    Publishing date 2023-05-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2063356-7
    ISSN 1438-9916 ; 0341-0501
    ISSN (online) 1438-9916
    ISSN 0341-0501
    DOI 10.1055/a-1870-7328
    Database Thieme publisher's database

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  2. Book: Molekulare Allergologie

    Kleine-Tebbe, Jörg / Jappe, Uta

    [Einführung mit kommentierten Kasuistiken]

    (Wissensakademie Allergie)

    2014  

    Author's details hrsg. von Jörg Kleine-Tebbe und Uta Jappe
    Series title Wissensakademie Allergie
    Keywords Allergie ; Molekulare Medizin
    Subject Medizin ; Genmedizin ; Hypersensibilität ; Allergose ; Allergische Krankheit ; Allergische Reaktion ; Allergien
    Subject code 616.97042
    Language German
    Size XIV, 154 S. : Ill., Kt., 21 cm
    Publisher Dustri-Verl. Feistle
    Publishing place München-Deisenhofen
    Publishing country Germany
    Document type Book
    Note Literaturangaben
    HBZ-ID HT018602538
    ISBN 978-3-87185-491-0 ; 3-87185-491-3
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: Nahrungsmittelallergien – Theorie und Praxis.

    Jappe, Uta

    Deutsche medizinische Wochenschrift (1946)

    2018  Volume 143, Issue 10, Page(s) 713–721

    Abstract: Allergies manifest differently in every patient: Even when the same allergen source is the causing agent, means of sensitization and complexity of symptoms can vary strongly across patients. This often complicates the prevention, diagnostics and therapy ... ...

    Title translation Food Allergy - Theory and Praxis.
    Abstract Allergies manifest differently in every patient: Even when the same allergen source is the causing agent, means of sensitization and complexity of symptoms can vary strongly across patients. This often complicates the prevention, diagnostics and therapy of food allergies - or even makes them impossible. This article gives an overview of the underlying immunological principles of food-allergies, as well as of the current therapeutic and diagnostic approaches.
    MeSH term(s) Food Hypersensitivity/diagnosis ; Food Hypersensitivity/immunology ; Food Hypersensitivity/prevention & control ; Food Hypersensitivity/therapy ; Humans
    Language German
    Publishing date 2018-05
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 200446-x
    ISSN 1439-4413 ; 0012-0472
    ISSN (online) 1439-4413
    ISSN 0012-0472
    DOI 10.1055/s-0043-121014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Breastfeeding: Maternally Transferred Allergens in Breast Milk: Protective or Sensitizing?

    Schocker, Frauke / Jappe, Uta

    Molecular nutrition & food research

    2022  Volume 66, Issue 15, Page(s) e2200066

    Abstract: According to a thorough literature search, the following allergen sources have been associated with allergy symptoms in the exclusively breastfed child: hen's egg, cow's milk, peanut, trout. Subsequently, several studies use the advantage of molecular ... ...

    Abstract According to a thorough literature search, the following allergen sources have been associated with allergy symptoms in the exclusively breastfed child: hen's egg, cow's milk, peanut, trout. Subsequently, several studies use the advantage of molecular allergology and investigate the potential transfer of single allergens into breastmilk. This is shown for caseins, whey proteins, gliadin, ovalbumin, ovomucoid, the peanut allergens Ara h 2 and Ara h 6, as well as the inhalant allergens Der p 1 and Blo t 5. It is still a matter of debate whether or not food allergens transferred via breastfeeding to the baby promote allergic sensitization or induce tolerance and via which mechanisms they may shift the immune response to the one or other side. Noteworthy, some breastfed children are described to be sensitized to foods before being exposed to solid foods, and this exposure may have occurred through breastmilk. In the light of these findings the investigation of food allergens transferred from the mother's diet into breastmilk and their impact on sensitization or allergy prevention remains a current topic in research. This review describes breastmilk in its composition and provides data on the identification of food allergens therein including human and mouse studies.
    MeSH term(s) Allergens ; Breast Feeding ; Female ; Food Hypersensitivity/prevention & control ; Humans ; Infant ; Infant, Newborn ; Milk Hypersensitivity ; Milk, Human/immunology
    Chemical Substances Allergens
    Language English
    Publishing date 2022-06-22
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2160372-8
    ISSN 1613-4133 ; 1613-4125
    ISSN (online) 1613-4133
    ISSN 1613-4125
    DOI 10.1002/mnfr.202200066
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Molekular-allergologische Aspekte der allergenspezifischen Immuntherapie.

    Jappe, Uta

    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete

    2017  Volume 68, Issue 4, Page(s) 271–281

    Abstract: Allergen-specific immunotherapy (SIT) does not achieve 100% efficacy, nor is there a reliable marker for therapy failure. However, advances in molecular allergology over the past few years have allowed a significantly improved characterization of the ... ...

    Title translation Molecular-allergological aspects of allergen-specific immunotherapy.
    Abstract Allergen-specific immunotherapy (SIT) does not achieve 100% efficacy, nor is there a reliable marker for therapy failure. However, advances in molecular allergology over the past few years have allowed a significantly improved characterization of the patients using molecular-allergological analysis methods (molecular phenotyping). Thus, major and minor allergens can be identified. In addition, the marker allergens for the severity of an allergic reaction, the pathological and therapeutic predictive marker allergens, and sensitization patterns are identified.
    Language German
    Publishing date 2017-04
    Publishing country Germany
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 2403-x
    ISSN 1432-1173 ; 0017-8470
    ISSN (online) 1432-1173
    ISSN 0017-8470
    DOI 10.1007/s00105-017-3958-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [No title information]

    Kleine-Tebbe, Jörg / Brans, Richard / Jappe, Uta

    Allergo Journal : interdisziplinare Zeitschrift fur Allergologie und Umweltmedizin : Organ der Deutschen Gesellschaft fur Allergie- und Immunitatsforschung

    2022  Volume 31, Issue 2, Page(s) 16–31

    Title translation Allergene - Auslöser der verschiedenen Allergievarianten.
    Language German
    Publishing date 2022-03-21
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1136943-7
    ISSN 0941-8849
    ISSN 0941-8849
    DOI 10.1007/s15007-022-4980-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Trained immunity and allergy: State of the art and future perspectives.

    Wanka, Lizzy / Jappe, Uta

    Allergy

    2020  Volume 76, Issue 4, Page(s) 1265–1267

    MeSH term(s) Humans ; Hypersensitivity/epidemiology
    Language English
    Publishing date 2020-10-23
    Publishing country Denmark
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 391933-x
    ISSN 1398-9995 ; 0105-4538
    ISSN (online) 1398-9995
    ISSN 0105-4538
    DOI 10.1111/all.14617
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Nahrungsmittelallergien – Theorie und Praxis

    Jappe, Uta

    DMW - Deutsche Medizinische Wochenschrift

    2018  Volume 143, Issue 10, Page(s) 713–721

    Abstract: Allergies manifest differently in every patient: Even when the same allergen source is the causing agent, means of sensitization and complexity of symptoms can vary strongly across patients. This often complicates the prevention, diagnostics and therapy ... ...

    Abstract Allergies manifest differently in every patient: Even when the same allergen source is the causing agent, means of sensitization and complexity of symptoms can vary strongly across patients. This often complicates the prevention, diagnostics and therapy of food allergies – or even makes them impossible. This article gives an overview of the underlying immunological principles of food-allergies, as well as of the current therapeutic and diagnostic approaches.
    Keywords Nahrungsmittelallergie ; Nahrungsmittelunverträglichkeit ; IgE-vermittelte Nahrungsmittelallergie ; Anaphylaxie ; allergenspezifische Immuntherapie ; food allergy ; IgE-mediated reaction ; food intolerance ; anaphylaxis ; allergen-specific immunotherapy
    Language German
    Publishing date 2018-05-01
    Publisher © Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 200446-x
    ISSN 1439-4413 ; 0012-0472
    ISSN (online) 1439-4413
    ISSN 0012-0472
    DOI 10.1055/s-0043-121014
    Database Thieme publisher's database

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  9. Article: Breastfeeding: Maternally Transferred Allergens in Breast Milk: Protective or Sensitizing?

    Schocker, Frauke / Jappe, Uta

    Molecular nutrition & food research. 2022 Aug., v. 66, no. 15

    2022  

    Abstract: According to a thorough literature search, the following allergen sources have been associated with allergy symptoms in the exclusively breastfed child: hen's egg, cow's milk, peanut, trout. Subsequently, several studies use the advantage of molecular ... ...

    Abstract According to a thorough literature search, the following allergen sources have been associated with allergy symptoms in the exclusively breastfed child: hen's egg, cow's milk, peanut, trout. Subsequently, several studies use the advantage of molecular allergology and investigate the potential transfer of single allergens into breastmilk. This is shown for caseins, whey proteins, gliadin, ovalbumin, ovomucoid, the peanut allergens Ara h 2 and Ara h 6, as well as the inhalant allergens Der p 1 and Blo t 5. It is still a matter of debate whether or not food allergens transferred via breastfeeding to the baby promote allergic sensitization or induce tolerance and via which mechanisms they may shift the immune response to the one or other side. Noteworthy, some breastfed children are described to be sensitized to foods before being exposed to solid foods, and this exposure may have occurred through breastmilk. In the light of these findings the investigation of food allergens transferred from the mother's diet into breastmilk and their impact on sensitization or allergy prevention remains a current topic in research. This review describes breastmilk in its composition and provides data on the identification of food allergens therein including human and mouse studies.
    Keywords breast feeding ; breast milk ; children ; eggs ; food research ; gliadin ; hens ; humans ; hypersensitivity ; immune response ; mice ; milk ; ovalbumin ; ovomucin ; peanuts ; trout ; whey
    Language English
    Dates of publication 2022-08
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note REVIEW
    ZDB-ID 2160372-8
    ISSN 1613-4133 ; 1613-4125
    ISSN (online) 1613-4133
    ISSN 1613-4125
    DOI 10.1002/mnfr.202200066
    Database NAL-Catalogue (AGRICOLA)

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  10. Book ; Thesis: Herstellung und Charakterisierung monoklonaler Antikörper gegen Paragonimus uterobilateralis hinsichtlich ihres Nutzens für die Immundiagnostik dieser humanpathogenen Parasitose

    Jappe, Uta

    1989  

    Author's details vorgelegt von Uta Jappe
    Size 101 S. : Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Hamburg, Univ., Diss., 1989
    HBZ-ID HT003858250
    Database Catalogue ZB MED Medicine, Health

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