LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 128

Search options

  1. Article: Uncovering the potential of APOD as a biomarker in gastric cancer: A retrospective and multi-center study.

    Wang, Zisong / Chen, Hongshan / Sun, Le / Wang, Xuanyu / Xu, Yihang / Tian, Sufang / Liu, Xiaoping

    Computational and structural biotechnology journal

    2024  Volume 23, Page(s) 1051–1064

    Abstract: Gastric cancer (GC) poses a significant health challenge worldwide, necessitating the identification of predictive biomarkers to improve prognosis. Dysregulated lipid metabolism is a well-recognized hallmark of tumorigenesis, prompting investigation into ...

    Abstract Gastric cancer (GC) poses a significant health challenge worldwide, necessitating the identification of predictive biomarkers to improve prognosis. Dysregulated lipid metabolism is a well-recognized hallmark of tumorigenesis, prompting investigation into apolipoproteins (APOs). In this study, we focused on apolipoprotein D (APOD) following comprehensive analyses of APOs in pan-cancer. Utilizing data from the TCGA-STAD and GSE62254 cohorts, we elucidated associations between APOD expression and multiple facets of GC, including prognosis, tumor microenvironment (TME), cancer biomarkers, mutations, and immunotherapy response, and identified potential anti-GC drugs. Single-cell analyses and immunohistochemical staining confirmed APOD expression in fibroblasts within the GC microenvironment. Additionally, we independently validated the prognostic significance of APOD in the ZN-GC cohort. Our comprehensive analyses revealed that high APOD expression in GC patients was notably associated with unfavorable clinical outcomes, reduced microsatellite instability and tumor mutation burden, alterations in the TME, and diminished response to immunotherapy. These findings provide valuable insights into the potential prognostic and therapeutic implications of APOD in GC.
    Language English
    Publishing date 2024-02-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2694435-2
    ISSN 2001-0370
    ISSN 2001-0370
    DOI 10.1016/j.csbj.2024.02.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Highly Efficient Removal of Lead/Cadmium by Phosphoric Acid-Modified Hydrochar Prepared from Fresh Banana Peels: Adsorption Mechanisms and Environmental Application.

    Ge, Qilong / Tian, Qi / Wang, Sufang / Zhang, Jing / Hou, Rui

    Langmuir : the ACS journal of surfaces and colloids

    2022  

    Abstract: In this work, a phosphoric acid ( ... ...

    Abstract In this work, a phosphoric acid (H
    Language English
    Publishing date 2022-11-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.2c02693
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Pathology of 2019 Novel Coronavirus Pneumonia: A Dynamic Disease Process.

    Tian, Sufang / Xiao, Shu-Yuan

    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

    2020  Volume 15, Issue 5, Page(s) e67–e68

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus ; Coronavirus Infections ; Humans ; Lung Neoplasms ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-04-27
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2432037-7
    ISSN 1556-1380 ; 1556-0864
    ISSN (online) 1556-1380
    ISSN 1556-0864
    DOI 10.1016/j.jtho.2020.03.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6664: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 652: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: CT-Guided Percutaneous Core Needle Biopsy in Typing and Subtyping Lung Cancer: A Comparison to Surgery.

    Zhang, Hanfei / Tian, Sufang / Wang, Shan / Liu, Songmei / Liao, Meiyan

    Technology in cancer research & treatment

    2022  Volume 21, Page(s) 15330338221086411

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Adenocarcinoma/pathology ; Biopsy, Large-Core Needle ; Humans ; Image-Guided Biopsy ; Lung/pathology ; Lung Neoplasms/diagnosis ; Lung Neoplasms/pathology ; Lung Neoplasms/surgery ; Retrospective Studies ; Tomography, X-Ray Computed/methods
    Language English
    Publishing date 2022-03-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2146365-7
    ISSN 1533-0338 ; 1533-0346
    ISSN (online) 1533-0338
    ISSN 1533-0346
    DOI 10.1177/15330338221086411
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5871: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Limited Role of Rhamnolipids on Cadmium Resistance for an Endogenous-Secretion Bacterium.

    Xing, Sufang / Yan, Zhen / Song, Chao / Tian, Huifang / Wang, Shuguang

    International journal of environmental research and public health

    2022  Volume 19, Issue 19

    Abstract: Rhamnolipids, a type of biosurfactant, represent a potential strategy for both enhancing organismic resistance and in situ remediation of heavy metals contaminations. In-depth study of the mechanism of rhamnolipids synthesis in response to heavy metals ... ...

    Abstract Rhamnolipids, a type of biosurfactant, represent a potential strategy for both enhancing organismic resistance and in situ remediation of heavy metals contaminations. In-depth study of the mechanism of rhamnolipids synthesis in response to heavy metals stress, is indispensable for a wide use of biosurfactant-secreting microbes in bioremediation. In this study, we employed the wild-type and the
    MeSH term(s) Bacteria/metabolism ; Biodegradation, Environmental ; Cadmium/metabolism ; Cadmium/toxicity ; Glycolipids ; Metals, Heavy/metabolism ; Micelles ; Pseudomonas aeruginosa/genetics ; Soil ; Surface-Active Agents/chemistry ; Surface-Active Agents/pharmacology
    Chemical Substances Glycolipids ; Metals, Heavy ; Micelles ; Soil ; Surface-Active Agents ; rhamnolipid ; Cadmium (00BH33GNGH)
    Language English
    Publishing date 2022-10-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph191912555
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Combing phosphorus-modified hydrochar and zeolite prepared from coal gangue for highly effective immobilization of heavy metals in coal-mining contaminated soil.

    Ge, Qilong / Tian, Qi / Hou, Rui / Wang, Sufang

    Chemosphere

    2021  Volume 291, Issue Pt 2, Page(s) 132835

    Abstract: Considering the adverse effects of heavy metals (HMs) on agriculture soil, in-situ immobilization has been paid great attention worldwide. P-modified biochar/hydrochar along with synthetic zeolite for efficient HMs immobilization in contaminated soil ... ...

    Abstract Considering the adverse effects of heavy metals (HMs) on agriculture soil, in-situ immobilization has been paid great attention worldwide. P-modified biochar/hydrochar along with synthetic zeolite for efficient HMs immobilization in contaminated soil becomes a promising choice. In this study, H
    MeSH term(s) Carbon ; Charcoal ; Coal ; Coal Mining ; Metals, Heavy/analysis ; Phosphorus ; Soil ; Soil Pollutants/analysis ; Zeolites
    Chemical Substances Coal ; Metals, Heavy ; Soil ; Soil Pollutants ; Zeolites (1318-02-1) ; Charcoal (16291-96-6) ; Phosphorus (27YLU75U4W) ; Carbon (7440-44-0)
    Language English
    Publishing date 2021-11-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2021.132835
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2540: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Self-Assembly of a Series of Carbazole-Based Vinyl-benzoxazole Derivatives in Gel Phases.

    Chen, Wei / Zhang, Sufang / Su, Tian / Nie, Yuanjun / He, Juan / Xue, Pengchong / Jia, Junhui

    Langmuir : the ACS journal of surfaces and colloids

    2023  Volume 39, Issue 35, Page(s) 12384–12391

    Abstract: A series of carbazole-based vinyl-benzoxazole derivatives have been synthesized in order to verify whether X-ray diffraction (XRD) simulation can give more information about intermolecular stacking in the gel phase. It was found that their gelation ... ...

    Abstract A series of carbazole-based vinyl-benzoxazole derivatives have been synthesized in order to verify whether X-ray diffraction (XRD) simulation can give more information about intermolecular stacking in the gel phase. It was found that their gelation capabilities were strongly dependent on the length of the alkyl chain. The compounds with shorter alkyl chains have lower critical gelation concentrations (CGCs) in nonpolar alkane and alcohols with longer carbon chains. On the other hand, compounds with long alkyl chains presented small CGCs in polar methanol. Powder XRD structure solution gave more information about intermolecular stacking than the traditional way of analyzing diffraction peaks to derive approximate molecular stacking patterns. The results verified that gelators had a similar head-to-tail π-stacking between aromatic groups in gel phases although different slipping angles existed. Moreover, ordered stacking between the alkyl chains was also present.
    Language English
    Publishing date 2023-08-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.3c01473
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article: Combing phosphorus-modified hydrochar and zeolite prepared from coal gangue for highly effective immobilization of heavy metals in coal-mining contaminated soil

    Ge, Qilong / Tian, Qi / Hou, Rui / Wang, Sufang

    Chemosphere. 2022 Mar., v. 291

    2022  

    Abstract: Considering the adverse effects of heavy metals (HMs) on agriculture soil, in-situ immobilization has been paid great attention worldwide. P-modified biochar/hydrochar along with synthetic zeolite for efficient HMs immobilization in contaminated soil ... ...

    Abstract Considering the adverse effects of heavy metals (HMs) on agriculture soil, in-situ immobilization has been paid great attention worldwide. P-modified biochar/hydrochar along with synthetic zeolite for efficient HMs immobilization in contaminated soil becomes a promising choice. In this study, H₃PO₄-modified hydrochar (BPH) derived from banana peels, and Na-X zeolite (ZL) prepared from coal gangue was applied individually and synergistically (1%BPH, 2%BPH 1%ZL, 2%ZL, and 1%BPH+1%ZL) to remediate a farmland soil polluted by Cd, Cu, and Pb near the coal-mining area. Compared with the mono-application of these two amendments, their combination significantly improved the soil organic carbon (SOC), electric conductivity (EC), and dehydrogenase activity. Besides, the addition of 1%CLH+1%ZL remarkably reduced the Cd, Cu, and Pb bioavailability by 67.01%, 57.01%, and 78.72%, respectively, in the soil after 100 d incubation by transforming these metals to more stable forms. The order of the HMs immobilization capacity for these two amendments was as follows: Pb > Cu > Cd. Moreover, the dominated immobilization mechanism of their synergistic application was that BPH could immobilize HMs by precipitation, complexation, and π−π electron-donor-acceptor interaction. The precipitation and complexation blocked the surface pores of BPH. The sustained release of phosphorus groups and radicals was prevented. This obstacle was possibly alleviated by adding ZL. Besides, the formation of cationic bridging, the enhancement of soil properties, and the physical adsorption of these amendments were also conducive to HMs immobilization in soil. This work indicated that co-application of BPH and ZL possibly was an excellent choice for immobilizing HMs in soil.
    Keywords adsorption ; agricultural soils ; bananas ; bioavailability ; biochar ; coal ; electrical conductivity ; hydrochars ; immobilization in soil ; oxidoreductases ; phosphorus ; polluted soils ; soil organic carbon ; zeolites
    Language English
    Dates of publication 2022-03
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2021.132835
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2540: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Evaluation of Pathology Residency Training Curriculum and Practice in the Hubei Province of China.

    Niu, Li / Yu, Fang / Qi, Bei / Hossur, Sushma / Tian, Sufang

    Archives of pathology & laboratory medicine

    2022  Volume 147, Issue 5, Page(s) 604–610

    Abstract: Context.—: The pathology residency program began in China in 2014. There has been no competency assessment on training programs in the Hubei province of China.: Objective.—: To evaluate the current residency training curriculum and resident ... ...

    Abstract Context.—: The pathology residency program began in China in 2014. There has been no competency assessment on training programs in the Hubei province of China.
    Objective.—: To evaluate the current residency training curriculum and resident performance in Hubei Province.
    Design.—: A 37-question online questionnaire was designed to cover general demographic information, diagnostic competency, expectations of ideal caseload for gross and preview, teaching patterns, examinations, research activities, weak points, and other topics in pathology practice.
    Results.—: A total of 166 participants, including 62 postgraduate year (PGY) 2, 49 PGY3, and 55 new practicing pathologists, responded to the survey. PGY3 residents were found to be more competent than PGY2 in diagnostic competency. Forty-five of 55 new practicing pathologists (81.8%) reported that they could sign out cases independently, whereas 10 of 55 (18.2%) were found to still need transitional time for learning before working independently. Some residents could sign out cytopathology cases and gained knowledge in immunohistochemistry and histochemical staining, while some residents did not receive adequate training in molecular pathology. The ideal caseloads for gross and preview during residency were greater than 5000 and 7000, respectively. Nonneoplastic diseases, neuropathology, dermatopathology, hematopathology, and soft tissue pathology were considered difficult subspecialties in pathology practice.
    Conclusions.—: While residents trained in Hubei Province have met the basic requirements for qualified pathologists, more efforts need to be made in many areas, such as a well-structured training curriculum and better-designed proficiency examinations. The findings of this study are of great importance to prioritizing training in the future.
    MeSH term(s) Humans ; Internship and Residency ; Curriculum ; Education, Medical, Graduate/methods ; Educational Measurement/methods ; Clinical Competence ; China
    Language English
    Publishing date 2022-07-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 194119-7
    ISSN 1543-2165 ; 0363-0153 ; 0096-8528 ; 0003-9985
    ISSN (online) 1543-2165
    ISSN 0363-0153 ; 0096-8528 ; 0003-9985
    DOI 10.5858/arpa.2021-0122-EP
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.36: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top