Result 1 - 10 of total 881
The American journal of dental science
2019 Volume 13, Issue 9, Page(s) 423
| Language | English |
|---|---|
| Publishing date | 2019-03-14 |
| Publishing country | United States |
| Document type | Journal Article |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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AEM education and training
2023 Volume 7, Issue 2, Page(s) e10852
Abstract: Objectives: Emergency department (ED) teams frequently perform under conditions of high stress. Stress exposure simulation (SES) is specifically designed to train recognition and management of stress responses under these conditions. Current approaches ... ...
| Abstract | Objectives: Emergency department (ED) teams frequently perform under conditions of high stress. Stress exposure simulation (SES) is specifically designed to train recognition and management of stress responses under these conditions. Current approaches to design and delivery of SES in emergency medicine are based on principles derived from other contexts and from anecdotal experience. However, the optimal design and delivery of SES in emergency medicine are not known. We aimed to explore participant experience to inform our approach. Methods: We performed an exploratory study in our Australian ED with doctors and nurses participating in SES sessions. We used a three-part framework-sources of stress, the impacts of that stress, and the strategies to mitigate-to inform our SES design and delivery and to guide our exploration of participant experience. Data were collected through a narrative survey and participant interviews and analyzed thematically. Results: There were 23 total participants (doctors Conclusions: We suggest that design and delivery of SES should follow health care simulation best practice, with stress adequately induced by authentic clinical scenarios and to avoid trickery or adding extraneous cognitive load. Facilitators leading learning conversations in SES sessions should develop a deep understanding of stress and emotional activation and focus on team-based strategies to mitigate harmful impacts of stress on performance. |
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| Language | English |
| Publishing date | 2023-03-30 |
| Publishing country | United States |
| Document type | Journal Article |
| ISSN | 2472-5390 |
| ISSN (online) | 2472-5390 |
| DOI | 10.1002/aet2.10852 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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2024 Volume 331, Issue 4, Page(s) 335–351
Abstract: Importance: Children with speech and language difficulties are at risk for learning and behavioral problems.: Objective: To review the evidence on screening for speech and language delay or disorders in children 5 years or younger to inform the US ... ...
| Abstract | Importance: Children with speech and language difficulties are at risk for learning and behavioral problems. Objective: To review the evidence on screening for speech and language delay or disorders in children 5 years or younger to inform the US Preventive Services Task Force. Data sources: PubMed/MEDLINE, Cochrane Library, PsycInfo, ERIC, Linguistic and Language Behavior Abstracts (ProQuest), and trial registries through January 17, 2023; surveillance through November 24, 2023. Study selection: English-language studies of screening test accuracy, trials or cohort studies comparing screening vs no screening; randomized clinical trials (RCTs) of interventions. Data extraction and synthesis: Dual review of abstracts, full-text articles, study quality, and data extraction; results were narratively summarized. Main outcomes and measures: Screening test accuracy, speech and language outcomes, school performance, function, quality of life, and harms. Results: Thirty-eight studies in 41 articles were included (N = 9006). No study evaluated the direct benefits of screening vs no screening. Twenty-one studies (n = 7489) assessed the accuracy of 23 different screening tools that varied with regard to whether they were designed to be completed by parents vs trained examiners, and to screen for global (any) language problems vs specific skills (eg, expressive language). Three studies assessing parent-reported tools for expressive language skills found consistently high sensitivity (range, 88%-93%) and specificity (range, 88%-85%). The accuracy of other screening tools varied widely. Seventeen RCTs (n = 1517) evaluated interventions for speech and language delay or disorders, although none enrolled children identified by routine screening in primary care. Two RCTs evaluating relatively intensive parental group training interventions (11 sessions) found benefit for different measures of expressive language skills, and 1 evaluating a less intensive intervention (6 sessions) found no difference between groups for any outcome. Two RCTs (n = 76) evaluating the Lidcombe Program of Early Stuttering Intervention delivered by speech-language pathologists featuring parent training found a 2.3% to 3.0% lower proportion of syllables stuttered at 9 months compared with the control group when delivered in clinic and via telehealth, respectively. Evidence on other interventions was limited. No RCTs reported on the harms of interventions. Conclusions and relevance: No studies directly assessed the benefits and harms of screening. Some parent-reported screening tools for expressive language skills had reasonable accuracy for detecting expressive language delay. Group parent training programs for speech delay that provided at least 11 parental training sessions improved expressive language skills, and a stuttering intervention delivered by speech-language pathologists reduced stuttering frequency. |
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| MeSH term(s) | Child ; Humans ; Language Development Disorders/diagnosis ; Preventive Health Services ; Speech ; Speech Disorders/diagnosis ; Speech Disorders/therapy ; Stuttering/etiology ; Practice Guidelines as Topic ; Infant ; Child, Preschool ; Mass Screening |
| Language | English |
| Publishing date | 2024-01-04 |
| Publishing country | United States |
| Document type | Systematic Review ; Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S. |
| ZDB-ID | 2958-0 |
| ISSN | 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484 |
| ISSN (online) | 1538-3598 |
| ISSN | 0254-9077 ; 0002-9955 ; 0098-7484 |
| DOI | 10.1001/jama.2023.24647 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Ua VI Zs.88: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
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Journal of insect science (Online)
2020 Volume 20, Issue 6
Abstract: Understanding collection methodologies and their limitations are essential when targeting specific arthropods for use in habitat restoration, conservation, laboratory colony formation, or when holistically representing local populations using ecological ... ...
| Abstract | Understanding collection methodologies and their limitations are essential when targeting specific arthropods for use in habitat restoration, conservation, laboratory colony formation, or when holistically representing local populations using ecological surveys. For dung beetles, the most popular collection methodology is baited traps, followed by light traps and unbaited flight-intercept traps during diversity surveys. A less common collection method, flotation, is assumed to be laborious and messy, and so only a handful of papers exist on its refinement and strengths. Our purpose was threefold: First, we tested the recovery and survival rates of Labarrus (=Aphodius) pseudolividus (Balthasar) and Onthophagus taurus (Schreber) when floating beetle-seeded dung pats to determine potential collection and safety issues. We collected 72.4 and 78% of the seeded L. pseudolividus and O. taurus, respectively, with >95% survival rating. Second, we developed a flotation-sieving technique that enables users to rapidly collect and passively sort dung beetles with less time and effort. Specifically, we often collected 50-100 g of wild dung beetles within a couple of hours of gathering dung and sorted them in a couple more by allowing dung beetles to sort themselves by size within a series of sieves; Third, we reviewed flotation-based advantages and disadvantages in comparison to other methodologies. |
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| MeSH term(s) | Animals ; Coleoptera/physiology ; Entomology/instrumentation ; Longevity ; Specimen Handling/instrumentation |
| Language | English |
| Publishing date | 2020-11-01 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 2049098-7 |
| ISSN | 1536-2442 ; 1536-2442 |
| ISSN (online) | 1536-2442 |
| ISSN | 1536-2442 |
| DOI | 10.1093/jisesa/ieaa083 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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2023 Volume 37, Issue 10, Page(s) 500–505
Abstract: Objective: To report upon a series of patients who have experienced the backout of distal interlocking screws after retrograde femoral nailing with the DePuy Synthes RFN-Advanced Retrograde Femoral Nailing System (DePuy Synthes, Raynham, MA).: Design!# ...
| Abstract | Objective: To report upon a series of patients who have experienced the backout of distal interlocking screws after retrograde femoral nailing with the DePuy Synthes RFN-Advanced Retrograde Femoral Nailing System (DePuy Synthes, Raynham, MA). Design: Retrospective case series. Patients: Twenty-seven skeletally mature patients with femoral shaft or distal femur fractures who underwent operative fixation with the DePuy Synthes RFN-Advanced Retrograde Femoral Nailing System with 8 patients subsequently experiencing backout of distal interlocking screws. Intervention: The study intervention included retrospective review of patient charts and radiographs. Main outcome measure: The incidence rate of distal interlocking screw backout. Results: Thirty percent of patients experienced the backout of at least 1 distal interlocking screw (mean: 1.625) after undergoing retrograde femoral nailing with the RFN-Advanced system. Thirteen total screws backed out postoperatively. Screw backout was identified an average of 61 days postoperatively (range: 30-139 days). All patients complained of implant prominence and pain along the medial or lateral aspect of the knee. Five patients elected to return to the operating room to remove the symptomatic implant. The oblique distal interlocking screws comprised 62% of screw backouts. Conclusions: Given the high incidence rate of this complication, the associated costs of reoperation, and patient discomfort, we believe that a further investigation into this implant complication is warranted. Level of evidence: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence. |
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| MeSH term(s) | Humans ; Fracture Fixation, Intramedullary/adverse effects ; Fracture Fixation, Intramedullary/methods ; Retrospective Studies ; Femur/surgery ; Bone Screws/adverse effects ; Radiography ; Femoral Fractures/diagnostic imaging ; Femoral Fractures/surgery ; Bone Nails |
| Language | English |
| Publishing date | 2023-06-09 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 639099-7 |
| ISSN | 1531-2291 ; 0890-5339 |
| ISSN (online) | 1531-2291 |
| ISSN | 0890-5339 |
| DOI | 10.1097/BOT.0000000000002646 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 2234: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
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The New Zealand medical journal
2017 Volume 130, Issue 1450, Page(s) 8–11
| Language | English |
|---|---|
| Publishing date | 2017-02-17 |
| Publishing country | New Zealand |
| Document type | Editorial |
| ZDB-ID | 390590-1 |
| ISSN | 1175-8716 ; 0028-8446 ; 0110-7704 |
| ISSN (online) | 1175-8716 |
| ISSN | 0028-8446 ; 0110-7704 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Ua VI Zs.396: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
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2019 Volume 21, Issue 4, Page(s) 670–676
Abstract: Background: Chronic pain is a significant public health problem that is associated with several negative health outcomes, including increased health care cost, decreased productivity, and prescription opioid misuse. Although efforts have been made to ... ...
| Abstract | Background: Chronic pain is a significant public health problem that is associated with several negative health outcomes, including increased health care cost, decreased productivity, and prescription opioid misuse. Although efforts have been made to curb the growing opioid epidemic in the United States, further research is needed to better understand individual difference factors that may be associated with greater pain and opioid misuse. Lower levels of health literacy, defined as the ability to obtain, understand, and use health information to make important decisions regarding health and medical care, has been associated with several chronic illnesses. Yet little work has examined the relationship between health literacy, pain, and opioid misuse among individuals with chronic pain. Methods: The current study examined health literacy in relation to current opioid misuse, severity of opioid dependence, pain severity, and pain disability among 445 adults with chronic pain (74.6% female, Mage [SD] = 38.45 [11.06] years). Results: Results indicated that health literacy was significantly negatively associated with each of the criterion variables. Conclusions: These results suggest that health literacy may contribute to opioid misuse and pain experience among individuals with chronic pain. Interventions targeting health literacy among individuals with chronic illness may help to address the opioid public health crisis. |
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| MeSH term(s) | Activities of Daily Living ; Adult ; Analgesics, Opioid/therapeutic use ; Anxiety/psychology ; Chronic Pain/drug therapy ; Chronic Pain/physiopathology ; Chronic Pain/psychology ; Depression/psychology ; Female ; Health Literacy ; Humans ; Male ; Middle Aged ; Opioid Epidemic ; Opioid-Related Disorders/physiopathology ; Opioid-Related Disorders/psychology ; Pain Measurement ; Patient Health Questionnaire ; Regression Analysis ; Surveys and Questionnaires |
| Chemical Substances | Analgesics, Opioid |
| Language | English |
| Publishing date | 2019-04-01 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 2015903-1 |
| ISSN | 1526-4637 ; 1526-2375 |
| ISSN (online) | 1526-4637 |
| ISSN | 1526-2375 |
| DOI | 10.1093/pm/pnz062 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 6119: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
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2022 Volume 36, Issue 11-12, Page(s) 737–751
Abstract: The primary cilium, a signaling organelle projecting from the surface of a cell, controls cellular physiology and behavior. The presence or absence of primary cilia is a distinctive feature of a given tumor type; however, whether and how the primary ... ...
| Abstract | The primary cilium, a signaling organelle projecting from the surface of a cell, controls cellular physiology and behavior. The presence or absence of primary cilia is a distinctive feature of a given tumor type; however, whether and how the primary cilium contributes to tumorigenesis are unknown for most tumors. Medulloblastoma (MB) is a common pediatric brain cancer comprising four groups: SHH, WNT, group 3 (G3), and group 4 (G4). From 111 cases of MB, we show that primary cilia are abundant in SHH and WNT MBs but rare in G3 and G4 MBs. Using WNT and G3 MB mouse models, we show that primary cilia promote WNT MB by facilitating translation of mRNA encoding β-catenin, a major oncoprotein driving WNT MB, whereas cilium loss promotes G3 MB by disrupting cell cycle control and destabilizing the genome. Our findings reveal tumor type-specific ciliary functions and underlying molecular mechanisms. Moreover, we expand the function of primary cilia to translation control and reveal a molecular mechanism by which cilia regulate cell cycle progression, thereby providing new frameworks for studying cilium function in normal and pathologic conditions. |
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| MeSH term(s) | Animals ; Brain Neoplasms/pathology ; Cell Cycle/genetics ; Cerebellar Neoplasms/genetics ; Cilia/genetics ; Humans ; Medulloblastoma/genetics ; Mice |
| Language | English |
| Publishing date | 2022-07-07 |
| Publishing country | United States |
| Document type | Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural |
| ZDB-ID | 806684-x |
| ISSN | 1549-5477 ; 0890-9369 |
| ISSN (online) | 1549-5477 |
| ISSN | 0890-9369 |
| DOI | 10.1101/gad.349596.122 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 2292: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG) |
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| Zs.MG 54: Show issues |
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Archives of disease in childhood
2010 Volume 8, Issue 46, Page(s) 265–278
| Language | English |
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| Publishing date | 2010-10-28 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 524-1 |
| ISSN | 1468-2044 ; 0003-9888 ; 1359-2998 |
| ISSN (online) | 1468-2044 |
| ISSN | 0003-9888 ; 1359-2998 |
| DOI | 10.1136/adc.8.46.265 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Um IV Zs.106: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
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| Zs.MA 3: Show issues |
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Journal of behavioral medicine
2020 Volume 44, Issue 1, Page(s) 66–73
Abstract: The opioid epidemic is a significant public health concern in the United States, particularly among adults with chronic pain. Considerable research suggests that people with mental health problems, including anxiety and depression, may experience more ... ...
| Abstract | The opioid epidemic is a significant public health concern in the United States, particularly among adults with chronic pain. Considerable research suggests that people with mental health problems, including anxiety and depression, may experience more opioid-related problems in the context of chronic pain. Yet, little work has examined potential mechanisms underyling these relations. Emotion dysregulation is one mechanistic factor that may link anxiety and depression and opioid-related problems among persons with chronic pain. Therefore, the current study examined the explanatory role of emotion dysregulation in the cross-sectional relationship between anxiety and depression problems and current opioid misuse and severity of opioid dependence among 431 adults with chronic pain who reported currently using opioid medications (74% female, M |
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| MeSH term(s) | Adult ; Analgesics, Opioid/adverse effects ; Anxiety/complications ; Chronic Pain/complications ; Chronic Pain/drug therapy ; Cross-Sectional Studies ; Depression/complications ; Depression/epidemiology ; Female ; Humans ; Male ; Opioid-Related Disorders/complications ; Opioid-Related Disorders/epidemiology ; United States |
| Chemical Substances | Analgesics, Opioid |
| Language | English |
| Publishing date | 2020-06-27 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 441827-x |
| ISSN | 1573-3521 ; 0160-7715 |
| ISSN (online) | 1573-3521 |
| ISSN | 0160-7715 |
| DOI | 10.1007/s10865-020-00169-8 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 1448: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
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