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  1. Book: The Bethesda handbook of clinical hematology

    Rodgers, Griffin P. / Young, Neal S.

    2024  

    Author's details editors Griffin P. Rodgers, Neal S. Young
    Language English
    Size x, 550 Seiten, Illustrationen
    Edition Fifth edition
    Publisher Wolters Kluwer
    Publishing place Philadelphia
    Publishing country United States
    Document type Book
    Note Zugang zu Online-Ausgabe über Code
    HBZ-ID HT030698721
    ISBN 978-1-9752-1183-7 ; 1-9752-1183-9
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Single-cell genomics in acquired bone marrow failure syndromes.

    Wu, Zhijie / Young, Neal S

    Blood

    2023  Volume 142, Issue 14, Page(s) 1193–1207

    Abstract: Mechanistic studies of immune bone marrow failure are difficult because of the scarcity of residual cells, the involvement of multiple cell types, and the inherent complexities of hematopoiesis and immunity. Single-cell genomic technologies and ... ...

    Abstract Mechanistic studies of immune bone marrow failure are difficult because of the scarcity of residual cells, the involvement of multiple cell types, and the inherent complexities of hematopoiesis and immunity. Single-cell genomic technologies and bioinformatics allow extensive, multidimensional analysis of a very limited number of cells. We review emerging applications of single-cell techniques, and early results related to disease pathogenesis: effector and target cell populations and relationships, cell-autonomous and nonautonomous phenotypes in clonal hematopoiesis, transcript splicing, chromosomal abnormalities, and T-cell receptor usage and clonality. Dense and complex data from single-cell techniques provide insights into pathophysiology, natural history, and therapeutic drug effects.
    MeSH term(s) Humans ; Pancytopenia ; Anemia, Aplastic/genetics ; Bone Marrow Failure Disorders ; Hematopoiesis/genetics ; Syndrome ; Genomics
    Language English
    Publishing date 2023-01-06
    Publishing country United States
    Document type Review ; Journal Article ; Research Support, N.I.H., Intramural
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood.2022018581
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online: Bethesda handbook of clinical hematology

    Rodgers, Griffin P. / Young, Neal S.

    2009  

    Title variant Handbook of clinical hematology
    Author's details [edited by] Griffin P. Rodgers, Neal Young
    Keywords Hematologic diseases - handbooks
    Language English
    Size 1 Online-Ressource
    Edition 2nd ed.
    Publisher Lippincott Williams & Wilkins
    Publishing place Baltimore
    Document type Book ; Online
    Note Includes bibliographical references and index
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 978-0-7817-7583-0 ; 0-7817-7583-3
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: Immunosuppression and stem cell stimulation to treat AA: clinical and biologic implications.

    Young, Neal S

    HemaSphere

    2019  Volume 3, Issue Suppl

    Language English
    Publishing date 2019-06-30
    Publishing country United States
    Document type Journal Article
    ISSN 2572-9241
    ISSN (online) 2572-9241
    DOI 10.1097/HS9.0000000000000211
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Somatic Mutations in "Benign" Disease. Reply.

    Mustjoki, Satu / Young, Neal S

    The New England journal of medicine

    2021  Volume 385, Issue 11, Page(s) e34

    MeSH term(s) Humans ; Mutation
    Language English
    Publishing date 2021-09-08
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2110545
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Towards treatments for VEXAS.

    Patel, Bhavisha A / Young, Neal S

    British journal of haematology

    2021  Volume 196, Issue 4, Page(s) 804–805

    MeSH term(s) Humans ; Mutation ; Myelodysplastic Syndromes
    Language English
    Publishing date 2021-11-03
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.17930
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book: Bone marrow failure syndromes

    Young, Neal S.

    2000  

    Author's details Neal S. Young
    Language English
    Size 223 S. : Ill., graph. Darst.
    Edition 1. ed., 1. print.
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT012742225
    ISBN 0-7216-7174-8 ; 978-0-7216-7174-1
    Database Catalogue ZB MED Medicine, Health

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  8. Article ; Online: Somatic Mutations in "Benign" Disease.

    Mustjoki, Satu / Young, Neal S

    The New England journal of medicine

    2021  Volume 384, Issue 21, Page(s) 2039–2052

    MeSH term(s) Clone Cells/physiology ; Clone Cells/ultrastructure ; DNA Mutational Analysis ; Germ-Line Mutation ; Hematologic Diseases/genetics ; Hematopoietic Stem Cells ; Hemoglobinuria, Paroxysmal/genetics ; Humans ; Immune System Diseases/genetics ; Mutagenesis/physiology ; Mutation ; Transformation, Genetic
    Language English
    Publishing date 2021-05-27
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMra2101920
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Aplastic Anemia.

    Young, Neal S

    The New England journal of medicine

    2018  Volume 379, Issue 17, Page(s) 1643–1656

    MeSH term(s) Adult ; Algorithms ; Anemia, Aplastic/diagnosis ; Anemia, Aplastic/drug therapy ; Anemia, Aplastic/etiology ; Anemia, Aplastic/therapy ; Benzoates/therapeutic use ; Bone Marrow Transplantation ; Child ; Hematopoietic Stem Cell Transplantation ; Humans ; Hydrazines/therapeutic use ; Immunosuppressive Agents/therapeutic use ; Pyrazoles/therapeutic use ; Receptors, Thrombopoietin/agonists ; Transplantation, Homologous
    Chemical Substances Benzoates ; Hydrazines ; Immunosuppressive Agents ; Pyrazoles ; Receptors, Thrombopoietin ; eltrombopag (S56D65XJ9G)
    Language English
    Publishing date 2018-12-13
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMra1413485
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book: Paroxysmal nocturnal hemoglobinuria and the glycosylphosphatidylinositol linked proteins

    Young, Neal S.

    2000  

    Title variant PNH and the GPI linked proteins ; glycosylphosphatidylinositol-linked GPI-linked
    Author's details ed. by Neal S. Young
    Keywords Paroxysmale nächtliche Hämoglobinurie ; Glykoproteine
    Subject Glykoproteide ; Glycoproteine ; Marchiafava-Micheli-Anämie
    Language English
    Size XIII, 279 S. : Ill., graph. Darst.
    Publisher Acad. Press
    Publishing place San Diego u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT012758881
    ISBN 0-12-772940-2 ; 978-0-12-772940-4
    Database Catalogue ZB MED Medicine, Health

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