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  1. Article ; Online: Pathophysiology of Covid-19 and host centric approaches in Ayurveda

    Prasad Dilip Pandkar / Vinay Sachdeva

    Journal of Ayurveda and Integrative Medicine, Vol 13, Iss 1, Pp 100380- (2022)

    2022  

    Abstract: The world is facing a global crisis and health emergency of COVID-19. Understanding of COVID-19 pathophysiology in ayurvedic host centric framework is prerequisite for apt use of Ayurveda. This paper reviews COVID-19 pathophysiology, clinical ... ...

    Abstract The world is facing a global crisis and health emergency of COVID-19. Understanding of COVID-19 pathophysiology in ayurvedic host centric framework is prerequisite for apt use of Ayurveda. This paper reviews COVID-19 pathophysiology, clinical presentations and prognosis in ayurvedic perspective. Concept of exogenous pathogenic diseases can be traced in fever, microbes, toxins, epidemics and seasonal regimens chapters of Ayurveda. Such exogenous diseases later manifest multi-system presentation according to involvement of different ‘Dosha’ and derangement of ‘Agni’. The pathology of COVID-19 is primarily that of Sannipata Jwara (fever) with involvement of respiratory system. Secondary manifestations include coagulopathies, cardiovascular, neural, and renal complications. Gastrointestinal system is closely associated with respiratory mechanism in ayurvedic pathophysiological conceptualization of Srotas. Abnormal immune responses in COVID-19 are result of abnormalities of Tridosha, Rakta (blood) and Ojus (Vital nectar). The initial phase is Vata-Kapha dominant whereas later stage of aggravated immune response is Vata-Pitta dominant. Alveolar damage, coagulopathies indicate Rakta dhatu vitiation. With this integrative understanding of COVID-19, we propose novel strategies for therapeutics and prophylaxis. Measures for ‘Conservation of Agni-bala’, ‘Attainment of Rakta- Pitta-Prana homeostasis and ‘Protection of Tri-Marma i.e. vital organs’ can be important Host based strategies for reduction in the mortality in COVID-19 and for better clinical outcomes. This host centric approach can make paradigm shift in management of this epidemic.
    Keywords Complimentary medicine ; Physiopathology ; Ayurveda ; SARS COV-2 ; Host centric ; Prophylaxis ; Miscellaneous systems and treatments ; RZ409.7-999
    Subject code 006
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  2. Article: COVID-19 patient with B cell lymphoma co-morbidity managed with co-administration of ayurvedic formulation.

    Dilip Pandkar, Prasad / Deshmukh, Santosh Raosaheb / Sachdeva, Vinay

    Journal of Ayurveda and integrative medicine

    2022  Volume 13, Issue 3, Page(s) 100632

    Abstract: Renaissance took place in Chaos and plague'. It was COVID-19 pandemic, when world realized ayurveda co-interventions are praiseworthy even in acute, infective and fatal conditions like COVID-19. We report perhaps first case of COVID-19 patient with ... ...

    Abstract 'Renaissance took place in Chaos and plague'. It was COVID-19 pandemic, when world realized ayurveda co-interventions are praiseworthy even in acute, infective and fatal conditions like COVID-19. We report perhaps first case of COVID-19 patient with cancer managed with poly-herbal ayurvedic formulation and integrated approach. In the first wave of COVID-19 (June 2020), a 47 year old male with history of Chronic kidney disease and active B Cell Lymphoma complained of fever, malaise, cattarah and ageusia. He was found positive on RT-PCR which was done promptly and was later treated in home quarantine with antipyretics, Vitamin C and Madhav rasayan a polyherbal preparation containing
    Language English
    Publishing date 2022-08-12
    Publishing country United States
    Document type Case Reports
    ISSN 0975-9476
    ISSN 0975-9476
    DOI 10.1016/j.jaim.2022.100632
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Pathophysiology of Covid-19 and host centric approaches in

    Pandkar, Prasad Dilip / Sachdeva, Vinay

    Journal of Ayurveda and integrative medicine

    2020  Volume 13, Issue 1, Page(s) 100380

    Abstract: The world is facing a global crisis and health emergency of COVID-19. Understanding of COVID-19 pathophysiology in ayurvedic host centric framework is prerequisite for apt use ... ...

    Abstract The world is facing a global crisis and health emergency of COVID-19. Understanding of COVID-19 pathophysiology in ayurvedic host centric framework is prerequisite for apt use of
    Language English
    Publishing date 2020-12-02
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 0975-9476
    ISSN 0975-9476
    DOI 10.1016/j.jaim.2020.11.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article: Pathophysiology of Covid-19 and host centric approaches in Ayurveda

    Pandkar, Prasad Dilip / Sachdeva, Vinay

    Journal of Ayurveda and integrative medicine. 2020 Nov. 25,

    2020  

    Abstract: The world is facing a global crisis and health emergency of COVID-19. Understanding of COVID-19 pathophysiology in ayurvedic host centric framework is prerequisite for apt use of Ayurveda. This paper reviews COVID-19 pathophysiology, clinical ... ...

    Abstract The world is facing a global crisis and health emergency of COVID-19. Understanding of COVID-19 pathophysiology in ayurvedic host centric framework is prerequisite for apt use of Ayurveda. This paper reviews COVID-19 pathophysiology, clinical presentations and prognosis in ayurvedic perspective. Concept of exogenous pathogenic diseases can be traced in fever, microbes, toxins, epidemics and seasonal regimens chapters of Ayurveda. Such exogenous diseases later manifest multi-system presentation according to involvement of different ‘Dosha’ and derangement of ‘Agni’. The pathology of COVID-19 is primarily that of Sannipata Jwara (fever) with involvement of respiratory system. Secondary manifestations include coagulopathies, cardiovascular, neural, and renal complications. Gastrointestinal system is closely associated with respiratory mechanism in ayurvedic pathophysiological conceptualization of Srotas. Abnormal immune responses in COVID-19 are result of abnormalities of Tridosha, Rakta (blood) and Ojus (Vital nectar). The initial phase is Vata-Kapha dominant whereas later stage of aggravated immune response is Vata-Pitta dominant. Alveolar damage, coagulopathies indicate Rakta dhatu vitiation. With this integrative understanding of COVID-19, we propose novel strategies for therapeutics and prophylaxis. Measures for ‘Conservation of Agni-bala’, ‘Attainment of Rakta- Pitta-Prana homeostasis and ‘Protection of Tri-Marma i.e. vital organs’ can be important Host based strategies for reduction in the mortality in COVID-19 and for better clinical outcomes. This host centric approach can make paradigm shift in management of this epidemic.
    Keywords Ayurvedic medicine ; COVID-19 infection ; blood ; disease prevention ; fever ; gastrointestinal system ; homeostasis ; immune response ; mortality ; nectar ; pathophysiology ; prognosis ; respiratory system ; therapeutics
    Language English
    Dates of publication 2020-1125
    Publishing place Elsevier B.V.
    Document type Article
    Note NAL-AP-2-clean ; Pre-press version
    ISSN 0975-9476
    DOI 10.1016/j.jaim.2020.11.010
    Database NAL-Catalogue (AGRICOLA)

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    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article: COVID-19 patient with B Cell Lymphoma co-morbidity managed with co-administration of Ayurvedic formulation

    Dilip Pandkar, Prasad / Raosaheb Deshmukh, Santosh / Sachdeva, Vinay

    Journal of Ayurveda and integrative medicine. 2022 Aug. 01,

    2022  

    Abstract: Renaissance took place in Chaos and plague’. It was COVID-19 pandemic, world realized that ayurveda co-interventions are praiseworthy even in acute and infective and fatal conditions like COVID-19. We report perhaps first case of COVID-19 patient with ... ...

    Abstract ‘Renaissance took place in Chaos and plague’. It was COVID-19 pandemic, world realized that ayurveda co-interventions are praiseworthy even in acute and infective and fatal conditions like COVID-19. We report perhaps first case of COVID-19 patient with cancer managed with poly-herbal ayurvedic formulation and integrated approach. In first wave of COVID-19 (June 2020), a 47 year old male with history of Chronic kidney disease and active B Cell Lymphoma complained of fever, malaise, cattarah and ageusia. He was found positive on RT-PCR which was done promptly and was later treated in home quarantine with antipyretics, Vitamin C and Madhav rasayan a polyherbal preparation containing Piper longum, Glycyrrhiza glabra, Eclipta alba, Achyranthes aspera, Embelia ribes and Aloe vera designed to modulate host response. It was challenging to treat a patient with cancer and immunocompromised status as he had recently finished his chemotherapy cycle (R-CHOP regimen). Patient well tolerated the intervention and recovered symptomatically. He did not developed any respiratory complications and oxygen saturation remained maintained. On 7th day RT-PCR was found to be negative. Plethora of literature is available on anti-viral and immunomodulatory efficacies of Ayurveda herbs based on in vitro studies. Such efficacies can be replicated at patient’s level if supported with wisdom of Ayurveda epistemology. Early diagnosis on RT-PCR and early inception of ayurveda medicine and diet interventions might be crucial element for better recovery.
    Keywords Achyranthes aspera ; Aloe vera ; Ayurvedic medicine ; B-cell lymphoma ; COVID-19 infection ; Eclipta prostrata ; Embelia ribes ; Glycyrrhiza glabra ; Piper longum ; antipyretics ; ascorbic acid ; diet ; drug therapy ; early diagnosis ; fever ; kidney diseases ; males ; oxygen ; patients ; plague ; quarantine
    Language English
    Dates of publication 2022-0801
    Publishing place Elsevier B.V.
    Document type Article
    Note Pre-press version
    ISSN 0975-9476
    DOI 10.1016/j.jaim.2022.100632
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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