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  1. Article: Ultrasound-guided thoracic erector spinae plane block for periprocedural analgesia in pigtail catheter insertion for palliative.

    Kumar, Abhishek / Mistry, Tuhin / Bhargava, Tanvi / Mahendru, Kiran

    Saudi journal of anaesthesia

    2021  Volume 15, Issue 2, Page(s) 234–236

    Language English
    Publishing date 2021-04-01
    Publishing country India
    Document type Journal Article
    ZDB-ID 2562174-9
    ISSN 0975-3125 ; 1658-354X
    ISSN (online) 0975-3125
    ISSN 1658-354X
    DOI 10.4103/sja.sja_1043_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Cervical Erector Spinae Plane Block for Giant Dermatofibrosarcoma Protuberans of Neck and Chest Wall: A Case Report.

    Mahendru, Kiran / Gupta, Nishkarsh / Rangarajan, Krithika / Kumar, Sunil / Chandrashekhara, Sheragaru Hanumanthappa

    AANA journal

    2023  Volume 91, Issue 3, Page(s) 168–171

    Abstract: We encountered a giant dermatofibrosarcoma protuberans (DFSP) of the neck and chest wall which presented a challenge in terms of perioperative analgesia management. In recent years, erector spinae plane (ESP) block has emerged as an effective and safe ... ...

    Abstract We encountered a giant dermatofibrosarcoma protuberans (DFSP) of the neck and chest wall which presented a challenge in terms of perioperative analgesia management. In recent years, erector spinae plane (ESP) block has emerged as an effective and safe analgesia technique for various surgical procedures as well as for chronic neuropathic pain without any untoward complications. A continuous lower cervical ESP block can be used successfully as an effective analgesic technique for extensive DFSP surgery involving the neck and chest wall area.
    MeSH term(s) Humans ; Thoracic Wall/surgery ; Pain, Postoperative ; Nerve Block/methods ; Dermatofibrosarcoma/surgery ; Dermatofibrosarcoma/complications ; Skin Neoplasms/complications
    Language English
    Publishing date 2023-05-25
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 603605-3
    ISSN 2162-5239 ; 0094-6354
    ISSN (online) 2162-5239
    ISSN 0094-6354
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1286: Show issues Location:
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  3. Article ; Online: Patient positioning under anesthesia during COVID-19 pandemic -Foresight risks to prepare, plan and execute.

    Mahendru, Kiran / Kumar, Abhishek / Bhargava, Tanvi

    Trends in anaesthesia & critical care

    2020  Volume 36, Page(s) 43–44

    Language English
    Publishing date 2020-10-07
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2210-8467
    ISSN (online) 2210-8467
    DOI 10.1016/j.tacc.2020.10.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Correction to: A comparison of two techniques of postoperative analgesia: lignocaine-fentanyl intravenous infusion and ropivacaine-fentanyl epidural infusion in patients undergoing cytoreductive cancer surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC)-prospective randomized control study.

    Mahendru, Kiran / Garg, Rakesh / Bharati, Sachidanand Jee / Kumar, Vinod / Gupta, Nishkarsh / Mishra, Seema / Bhatnagar, Sushma / Ray, Mukurdipi / Deo, Suryanarayana

    Langenbeck's archives of surgery

    2023  Volume 408, Issue 1, Page(s) 370

    Language English
    Publishing date 2023-09-22
    Publishing country Germany
    Document type Published Erratum
    ZDB-ID 1423681-3
    ISSN 1435-2451 ; 1435-2443
    ISSN (online) 1435-2451
    ISSN 1435-2443
    DOI 10.1007/s00423-023-03113-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  5. Article ; Online: A comparison of two techniques of postoperative analgesia: lignocaine-fentanyl intravenous infusion and ropivacaine-fentanyl epidural infusion in patients undergoing cytoreductive cancer surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC)-prospective randomized control study.

    Mahendru, Kiran / Garg, Rakesh / Bharati, Sachidanand Jee / Kumar, Vinod / Gupta, Nishkarsh / Mishra, Seema / Bhatnagar, Sushma / Ray, Mukurdipi / Deo, Suryanarayana

    Langenbeck's archives of surgery

    2023  Volume 408, Issue 1, Page(s) 330

    Abstract: Background: Extensive surgical dissection, hemodynamic alterations associated with cytoreductive surgery (CRS), and hyperthermic intraperitoneal chemotherapy (HIPEC) make pain management challenging. We hypothesized that infusions of intravenous ... ...

    Abstract Background: Extensive surgical dissection, hemodynamic alterations associated with cytoreductive surgery (CRS), and hyperthermic intraperitoneal chemotherapy (HIPEC) make pain management challenging. We hypothesized that infusions of intravenous lignocaine and fentanyl provide comparable analgesia to epidural ropivacaine and fentanyl in these patients.
    Methods: Fifty patients scheduled to undergo CRS and HIPEC were enrolled in the study. The patients in group IV (Intravenous) received a bolus dose of 1.5 mg/kg lignocaine over 15 min, starting approximately 15 min before the surgical incision and fentanyl 0.5 mcg/kg, about 2 min before the surgical incision, following which patient received lignocaine infusion at 1 mg/kg/hr and fentanyl infusion at 0.5 mcg/kg/hr intraoperatively. Patients in group EPI (Epidural) received 6 mL of Ropivacaine 0.2% and fentanyl (2mcg/mL) approximately 15 min before surgical incision, followed by continuous infusion at the rate of 5 mL/hr. The procedure for induction and maintenance of anesthesia was standardized for both groups. In the postoperative period, the infusion of analgesics was reduced to half the intraoperative rates and continued for 24 h.
    Results: Demographic profile and clinical parameters were comparable between both groups (p > 0.05). There was no difference between the number of fentanyl doses given in the IV group [Langenbecks Arch Chir 373(3):189-196, 4, IQR (2-11)] and the EPI group [Reg Anesth Pain Med 35(4):370-376, 12, IQR (5-21)] in the postoperative period (p = 0.229). The need for intraoperative rescue analgesia was comparable among the groups (p = 0.882).
    Conclusion: The two techniques, epidural (ropivacaine and fentanyl) and IV (lignocaine and fentanyl) infusions, provide comparable analgesia in patients undergoing CRS and HIPEC.
    Trial registration number: CTRI/2020/08/027052 dated 09/08/2020.
    MeSH term(s) Humans ; Infusions, Intravenous ; Cytoreduction Surgical Procedures ; Ropivacaine ; Hyperthermic Intraperitoneal Chemotherapy ; Fentanyl ; Lidocaine ; Prospective Studies ; Surgical Wound ; Analgesia, Epidural ; Neoplasms
    Chemical Substances Ropivacaine (7IO5LYA57N) ; Fentanyl (UF599785JZ) ; Lidocaine (98PI200987)
    Language English
    Publishing date 2023-08-24
    Publishing country Germany
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 1423681-3
    ISSN 1435-2451 ; 1435-2443
    ISSN (online) 1435-2451
    ISSN 1435-2443
    DOI 10.1007/s00423-023-03078-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.10: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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  6. Article: Patient positioning under anesthesia during COVID-19 pandemic –Foresight risks to prepare, plan and execute

    Mahendru, Kiran / Kumar, Abhishek / Bhargava, Tanvi

    Trends in Anaesthesia and Critical Care

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #838269
    Database COVID19

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  7. Article: Effect of Meditation and Breathing Exercises on the Well-being of Patients with SARS-CoV-2 Infection under Institutional Isolation: A Randomized Control Trial.

    Mahendru, Kiran / Pandit, Anuja / Singh, Vishwajeet / Choudhary, Nandan / Mohan, Anant / Bhatnagar, Sushma

    Indian journal of palliative care

    2021  Volume 27, Issue 4, Page(s) 490–494

    Abstract: Objectives: The corona virus disease-19 (COVID-19) pandemic has affected every domain of human health be it physical or mental. The uncertainty of disease progression in patients with SARS-CoV-2 infection can lead to major psychological and psychiatric ... ...

    Abstract Objectives: The corona virus disease-19 (COVID-19) pandemic has affected every domain of human health be it physical or mental. The uncertainty of disease progression in patients with SARS-CoV-2 infection can lead to major psychological and psychiatric concerns that should not be overlooked. The interventions should be directed to the vulnerable population to help them mitigate the stress and anxiety caused by the infection and isolation. We evaluated the effect of meditation and breathing exercises on the well-being of patients with SARS-CoV-2 infection under institutional isolation.
    Materials and methods: We conducted a randomized control trial on 84 subjects, 18 years and above, asymptomatic, or mildly symptomatic SARS-CoV-2 infected patients under institutional isolation. Subjects were randomly and equally divided into a control group and interventional group. We measured the depression, anxiety, and stress levels as well as quality of sleep in patients after 7 days of meditation and breathing exercises in the intervention group versus standard care in the control group.
    Results: Meditation and breathing exercises had a statistically significant effect on the depression level (P < 0.001), stress level (P = 0.004), and the quality of sleep [trouble falling asleep (P = 0.007), trouble staying asleep (P = 0.004), and feel tired after waking up in the morning (P = 0.003)]. Further, the positive effect of intervention on the level of anxiety in patients under isolation was also observed; however, the difference was not found to be statistically significant (P = 0.528).
    Conclusion: Meditation and breathing exercises have positive effects on depression, stress levels, and quality of sleep in COVID-19 positive patients under strict institutional isolation.
    Language English
    Publishing date 2021-11-26
    Publishing country United States
    Document type Journal Article
    ISSN 0973-1075
    ISSN 0973-1075
    DOI 10.25259/IJPC_40_21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Patient positioning under anesthesia during COVID-19 pandemic –Foresight risks to prepare, plan and execute

    Mahendru, Kiran / Kumar, Abhishek / Bhargava, Tanvi

    Trends in Anaesthesia and Critical Care ; ISSN 2210-8440

    2020  

    Keywords Anesthesiology and Pain Medicine ; Critical Care and Intensive Care Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/j.tacc.2020.10.001
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Need for Palliative Care in Patient with Rheumatoid Arthritis: A Cross-sectional Observational Study.

    Mahendru, Kiran / Gupta, Nishkarsh / Soneja, Manish / Malhotra, Rajeev Kumar / Kumar, Vinod / Garg, Rakesh / Bharati, Sachidanand Jee / Mishra, Seema / Bhatnagar, Sushma

    Indian journal of palliative care

    2021  Volume 27, Issue 2, Page(s) 275–280

    Abstract: Objectives: Rheumatoid arthritis (RA) is a chronic disorder causing inflammation in the joints and achieving remission is often the primary goal of physicians. We evaluated the suffering from RA and assessed the need for palliative care services in ... ...

    Abstract Objectives: Rheumatoid arthritis (RA) is a chronic disorder causing inflammation in the joints and achieving remission is often the primary goal of physicians. We evaluated the suffering from RA and assessed the need for palliative care services in these patients.
    Materials and methods: This cross-sectional observational study was done in 100 adult RA cases who attended the outpatient department. The Disease Activity Score 28 (DAS28), Health Assessment Questionnaire Disability Index, depression, anxiety and stress score, Short Form 36 Health Survey and numeric rating scale were assessed. The relationship between DAS28 with the other parameters and scores was assessed using Spearman's rho correlation coefficient.
    Results: About 90% of patients in our study were female and majority (50%) had a moderate disease activity. The DAS28 showed a positive correlation with the degree of depression (r = 0.671,
    Conclusion: RA patients with high disease activity suffer from depression, anxiety, stress and poor QoL. Palliative care physicians and rheumatologists must be vested with the power to provide comprehensive care to these patients.
    Language English
    Publishing date 2021-08-12
    Publishing country United States
    Document type Journal Article
    ISSN 0973-1075
    ISSN 0973-1075
    DOI 10.25259/IJPC_395_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Screening of bioconstituents and in vitro cytotoxicity of Clematis gouriana leaves.

    Rana, Shalika / Rawat, Kiran / Mahendru, Madhavi / Padwad, Yogendra / Pakade, Yogesh B / Lal, Brij / Bhushan, Shashi

    Natural product research

    2015  Volume 29, Issue 23, Page(s) 2242–2246

    Abstract: Clematis gouriana (Ranunculaceae), a perennial herb, is used by the local inhabitants of the western Himalayan region for its medicinal properties. Major bioconstituents of C. gouriana leaves using different solvent extracts were obtained and analysed. ... ...

    Abstract Clematis gouriana (Ranunculaceae), a perennial herb, is used by the local inhabitants of the western Himalayan region for its medicinal properties. Major bioconstituents of C. gouriana leaves using different solvent extracts were obtained and analysed. The results revealed promising contents of phenolics (from 18.19 ± 0.10 to 22.17 ± 0.10 mg g(-1)) as gallic acid and flavonoids (from 2.83 ± 0.01 to 6.52 ± 0.08 mg g(-1)) as quercetin equivalent in different extracts. Aqueous acetone extract showed higher antioxidant activity with IC50 value of 129.11 and 25.35 μg mL(-1) against DPPH and ABTS free radicals, respectively. Antioxidant yield ranged from 16.87 ± 0.27 to 24.48 ± 0.13 mg g(-1) of Trolox equivalent in different extracts as measured by the FRAP assay. Furthermore, ethylacetate extract exhibited strong in vitro cytotoxicity against Chinese hamster ovary and glioma cell lines. Proximate composition (proteins, fats, ash and minerals) of C. gouriana leaves was also assessed. Results demonstrated the potential of C. gouriana bioconstituents as nutraceuticals.
    MeSH term(s) Animals ; Antioxidants/chemistry ; Antioxidants/isolation & purification ; CHO Cells ; Cell Line, Tumor ; Clematis/chemistry ; Cricetulus ; Flavonoids/chemistry ; Flavonoids/isolation & purification ; Humans ; Inhibitory Concentration 50 ; Phenols/chemistry ; Phenols/isolation & purification ; Plant Extracts/chemistry ; Plant Leaves/chemistry ; Plants, Medicinal/chemistry
    Chemical Substances Antioxidants ; Flavonoids ; Phenols ; Plant Extracts
    Language English
    Publishing date 2015
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2014.1000891
    Database MEDical Literature Analysis and Retrieval System OnLINE

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