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Article: Sleep Habits, Academic Performance and Health Behaviors of Adolescents in Southern Greece.

Alexopoulou, Christina / Fountoulaki, Maria / Papavasileiou, Antigone / Kondili, Eumorfia

2024 Volume 12, Issue 7

Abstract: Adolescents often experience insufficient sleep and have unhealthy sleep habits. Our aim was to investigate the sleep patterns of secondary education students in Heraklion, Crete, Greece and their association with school performance and health habits. We ...

Abstract	Adolescents often experience insufficient sleep and have unhealthy sleep habits. Our aim was to investigate the sleep patterns of secondary education students in Heraklion, Crete, Greece and their association with school performance and health habits. We conducted a community-based cross-sectional study with 831 students aged 13-19 years who completed an online self-reported questionnaire related to sleep and health habits. The data are mostly numerical or categorical, and an analysis was performed using
Language	English
Publishing date	2024-04-03
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2721009-1
ISSN	2227-9032
ISSN	2227-9032
DOI	10.3390/healthcare12070775
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Article ; Online: Hepatitis E virus and hepatitis A virus exposures in an apparently healthy high-risk population in Italy.

Rapicetta, M / Monarca, R / Kondili, L A / Chionne, P / Madonna, E / Madeddu, G / Soddu, A / Candido, A / Carbonara, S / Mura, M S / Starnini, G / Babudieri, S

Infection

2012 Volume 41, Issue 1, Page(s) 69–76

Abstract: Purpose: The prevalence of anti-hepatitis E virus (HEV) and anti-hepatitis A virus (HAV), as well ...

Abstract	Purpose: The prevalence of anti-hepatitis E virus (HEV) and anti-hepatitis A virus (HAV), as well as the possible links with socio-demographic and other viral risks factors, were evaluated in an inmates population. Methods: The study population consisted of 973 consecutively recruited inmates of eight Italian prisons. Results: The anti-HEV prevalence was 11.6 % (113/973). It increased significantly by age (χ(2) for linear trend: p = 0.001) and was significantly higher among non-Italian compared to Italian inmates (15.3 vs. 10.7 %, respectively). Age >40 years [odds ratio (OR) 2.1; 95 % confidence interval (CI) 1.4-3.1], non-Italian citizenship (OR 1.8; 95 % CI 1.1-2.9) and anti-HIV seropositivity (OR 2.2; 95 % CI 1.2-4.2) were the only factors independently associated to anti-HEV positivity by logistic regression analysis. The overall anti-HAV prevalence was 86.4 %, and was significantly higher in non-Italian compared to Italian prisoners (92.6 vs. 84.9 %, respectively; p = 0.02). Age older than 40 years (OR 3.6; 95 % CI 2.2-5.9), <5 years formal education (OR 2.1; 95 % CI 1.3-3.2) and non-Italian nationality (OR 2.7; 95 % CI 1.5-4.8) were factors independently associated to anti-HAV positivity by the logistic regression analysis. Conclusions: Compared to the general population, significantly higher anti-HEV and anti-HAV prevalences were observed in an inmates population in Italy. Old age and non-Italian nationality were factors independently related to both HEV and HAV exposures. This data suggest the important role of low socio-economic factors in the transmission of both infections in high-risk populations. The possible epidemiological and/or pathogenetic links between HEV and HIV exposures need to be studied further.
MeSH term(s)	Adolescent ; Adult ; Age Factors ; Aged ; Female ; Hepatitis A/epidemiology ; Hepatitis A virus/immunology ; Hepatitis Antibodies/blood ; Hepatitis Antibodies/immunology ; Hepatitis E/epidemiology ; Hepatitis E virus/immunology ; Humans ; Italy/epidemiology ; Male ; Middle Aged ; Population Surveillance ; Risk Factors ; Seroepidemiologic Studies ; Young Adult
Chemical Substances	Hepatitis Antibodies
Language	English
Publishing date	2012-12-22
Publishing country	Germany
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	185104-4
ISSN	1439-0973 ; 0300-8126 ; 0173-2129
ISSN (online)	1439-0973
ISSN	0300-8126 ; 0173-2129
DOI	10.1007/s15010-012-0385-8
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Article ; Online: Driving pressure of respiratory system and lung stress in mechanically ventilated patients with active breathing.

Stamatopoulou, Vaia / Akoumianaki, Evangelia / Vaporidi, Katerina / Stamatopoulos, Efstathios / Kondili, Eumorfia / Georgopoulos, Dimitrios

Critical care (London, England)

2024 Volume 28, Issue 1, Page(s) 19

Abstract: ... elastance (E: Results: In 44,836 occluded breaths, ΔP: Conclusion: In patients with ARDS ventilated ...

Abstract	Background: During control mechanical ventilation (CMV), the driving pressure of the respiratory system (ΔP Methods: Thirty-one patients instrumented with esophageal and gastric catheters (n = 22) were switched from CMV to PAV+ and respiratory variables were recorded, over a maximum of 24 h. To decrease the contribution of random breaths with irregular characteristics, a 7-breath moving average technique was applied. In each patient, measurements were also analyzed per deciles of increasing lung elastance (E Results: In 44,836 occluded breaths, ΔP Conclusion: In patients with ARDS ventilated with PAV+, injurious tidal lung stress and effort were infrequent. In the presence of expiratory muscle activity, ΔP
MeSH term(s)	Humans ; Respiration, Artificial/adverse effects ; Respiration, Artificial/methods ; Positive-Pressure Respiration/methods ; Lung ; Respiratory Distress Syndrome/therapy ; Respiration ; Cytomegalovirus Infections ; Respiratory Mechanics/physiology ; Tidal Volume/physiology
Language	English
Publishing date	2024-01-12
Publishing country	England
Document type	Observational Study ; Journal Article
ZDB-ID	2041406-7
ISSN	1466-609X ; 1364-8535
ISSN (online)	1466-609X
ISSN	1364-8535
DOI	10.1186/s13054-024-04797-3
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Article: A Fatal Case of Presumptive Diagnosis of Leptospirosis Involving the Central Nervous System.

Alexopoulou, Christina / Proklou, Athanasia / Kokkini, Sofia / Raissaki, Maria / Konstantinou, Ioannis / Kondili, Eumorfia

Healthcare (Basel, Switzerland)

2024 Volume 12, Issue 5

Abstract: Leptospirosis is a reemerging zooanthroponosis with a worldwide distribution, though it has a higher incidence in areas with tropical climate. A characteristic finding of the disease is its wide spectrum of symptoms and organ involvement, as it can ... ...

Abstract	Leptospirosis is a reemerging zooanthroponosis with a worldwide distribution, though it has a higher incidence in areas with tropical climate. A characteristic finding of the disease is its wide spectrum of symptoms and organ involvement, as it can appear either with very mild flu-like manifestations or with multiorgan failure, affecting the central nervous system (CNS) with a concomitant hepatorenal dysfunction (Weil's syndrome) and significant high mortality rate. We report herein a fatal case of a 25 years old female, previously healthy, with impaired neurological status. She had high fever and severe multiorgan failure. The clinical data and the epidemiological factors were not conclusive for the diagnosis, and the first serology test from the cerebrospinal fluid (CSF) and sera samples were negative. When the repetition of the blood test showed elevated IgM antibodies, Leptospirosis was the presumptive diagnosis. Although CNS involvement is rare, the diagnosis should be considered when there is an elevated risk of exposure. The diagnostic protocol should encompass direct evidence of the bacterium and indirect measurement of antibodies. Timely detection and management are imperative to forestall complications and fatality associated with the disease.
Language	English
Publishing date	2024-02-29
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2721009-1
ISSN	2227-9032
ISSN	2227-9032
DOI	10.3390/healthcare12050568
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Article: Seroprevalence of hepatitis E virus (HEV) antibody and the possible association with chronic liver disease: a case-control study in Albania.

Kondili, L A / Chionne, P / Porcaro, A / Madonna, E / Taffon, S / Resuli, B / Taliani, G / Rapicetta, M

Epidemiology and infection

2006 Volume 134, Issue 1, Page(s) 95–101

Abstract: A case-control study involving 109 in-patients with chronic liver disease and 190 in-patients with no apparent liver disease was conducted to evaluate the seroprevalence of anti-HEV antibodies and the possible association with chronic liver disease. ... ...

Abstract	A case-control study involving 109 in-patients with chronic liver disease and 190 in-patients with no apparent liver disease was conducted to evaluate the seroprevalence of anti-HEV antibodies and the possible association with chronic liver disease. Among cases, the anti-HEV prevalence was 36.6% which increased significantly by age; among controls, the prevalence was 12.1% (P<0.05) and was similar among age groups <60 years. Among cases, aged >50 years (OR 4.0, 95% CI 1.4-11) and the presence of end stage liver disease (ESLD) (OR 4.3, 95% CI 1.4-12.8) were associated independently with anti-HEV positivity. The mean optical density, determined by anti-HEV immunoenzymatic test, was significantly higher among patients with ESLD, compared to the other patients. These results indicate that there is a high seroprevalence of anti-HEV in patients with chronic liver disease and a possible association between HEV infection and/or anti-HEV production and advanced stage chronic liver disease.
MeSH term(s)	Age Factors ; Aged ; Albania/epidemiology ; Antibodies, Viral/analysis ; Case-Control Studies ; Chronic Disease ; Female ; Hepatitis E/complications ; Hepatitis E/epidemiology ; Hepatitis E/virology ; Hepatitis E virus ; Humans ; Liver Diseases/epidemiology ; Liver Diseases/virology ; Male ; Middle Aged ; Seroepidemiologic Studies
Chemical Substances	Antibodies, Viral
Language	English
Publishing date	2006-02
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	632982-2
ISSN	1469-4409 ; 0950-2688
ISSN (online)	1469-4409
ISSN	0950-2688
DOI	10.1017/S095026880500470X
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Article ; Online: Thoracic ultrasound use in hospitalized and ambulatory adult patients: a quantitative picture.

Xirouchaki, N / Bolaki, M / Psarologakis, C / Pediaditis, E / Proklou, A / Papadakis, E / Kondili, E / Georgopoulos, D

The ultrasound journal

2024 Volume 16, Issue 1, Page(s) 11

Abstract: Introduction and objectives: Thoracic ultrasound (TUS) has been established as a powerful diagnostic and monitoring tool in the Intensive Care Unit (ICU). However, studies outside the critical care setting are scarce. The aim of this study was to ... ...

Abstract	Introduction and objectives: Thoracic ultrasound (TUS) has been established as a powerful diagnostic and monitoring tool in the Intensive Care Unit (ICU). However, studies outside the critical care setting are scarce. The aim of this study was to investigate the value of TUS for hospitalized or ambulatory community patients. Materials and methods: This was a retrospective study conducted from 2016 to 2020 in the TUS clinic at Heraklion University Hospital. TUS examination was performed using a standard ultrasound machine (EUB HITACHI 8500), and a high-frequency microconvex probe (5-8 MHz). Patients had been referred by their primary physician to address a range of different questions. The various respiratory system entities were characterised according to internationally established criteria. Results: 762 TUS studies were performed on 526 patients due to underlying malignancy (n = 376), unexplained symptoms/signs (n = 53), pregnancy related issues (n = 42), evaluation of abnormal findings in X-ray (n = 165), recent surgery/trauma (n = 23), recent onset respiratory failure (n = 12), acute respiratory infection (n = 66) and underlying non-malignant disease (n = 25). Pleural effusion was the commonest pathologic entity (n = 610), followed by consolidation (n = 269), diaphragmatic dysfunction/paradox (n = 174) and interstitial syndrome (n = 53). Discrepancies between chest X-ray and ultrasonographic findings were demonstrated in 96 cases. The TUS findings guided invasive therapeutic management in 448 cases and non-invasive management in 43 cases, while follow-up monitoring was decided in 271 cases. Conclusions: This study showed that TUS can identify the most common respiratory pathologic entities encountered in hospitalized and community ambulatory patients, and is especially useful in guiding the decision making process in a diverse group of patients.
Language	English
Publishing date	2024-02-21
Publishing country	Italy
Document type	Journal Article
ZDB-ID	2965029-X
ISSN	2524-8987 ; 2036-3176
ISSN (online)	2524-8987
ISSN	2036-3176
DOI	10.1186/s13089-024-00359-4
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Article: Disseminated Bacillus Calmette-Guérin (BCG) infection presenting as severe respiratory failure and septic shock.

Marouli, Diamantina / Pappas, Charalampos / Raissaki, Maria / Proklou, Athanasia / Papadakis, Eleftherios / Kondili, Eumorfia

Germs

2023 Volume 13, Issue 3, Page(s) 277–281

Abstract: Introduction: Intravesical Bacillus Calmette-Guérin (BCG) instillation is the most effective adjuvant therapy for superficial urinary bladder carcinoma, prolonging disease-free survival. Although it is usually well tolerated, moderate to severe local or ...

Abstract	Introduction: Intravesical Bacillus Calmette-Guérin (BCG) instillation is the most effective adjuvant therapy for superficial urinary bladder carcinoma, prolonging disease-free survival. Although it is usually well tolerated, moderate to severe local or systemic infectious complications, including sepsis involving multiple organs, may occur. Case report: We report the unusual case of a man in his mid '70s who presented with septic shock and severe acute respiratory failure requiring intubation. Lack of response to antibiotics, history of intravesical BCG instillation and consistent imaging findings led to further investigations, with bronchoalveolar lavage (BAL) fluid polymerase chain reaction (PCR) results indicating pneumonitis due to Conclusions: Due to its non-specific clinical presentation and the relatively low diagnostic yield of conventional microbiological tests, a high index of suspicion is required for prompt diagnosis and treatment of systemic BCG infection. PCR-based assays for mycobacterial DNA identification may represent a valuable tool facilitating timely diagnosis of this uncommon, yet potentially life-threatening infection.
Language	English
Publishing date	2023-09-30
Publishing country	Romania
Document type	Case Reports
ZDB-ID	2649305-6
ISSN	2248-2997
ISSN	2248-2997
DOI	10.18683/germs.2023.1395
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Article ; Online: Effects of Sedatives on Sleep Architecture Measured With Odds Ratio Product in Critically Ill Patients.

Georgopoulos, Dimitris / Kondili, Eumorfia / Alexopoulou, Christina / Younes, Magdy

Critical care explorations

2021 Volume 3, Issue 8, Page(s) e0503

Abstract: Evaluation of sleep quality in critically ill patients is difficult using conventional scoring criteria. The aim of this study was to examine sleep in critically ill patients with and without light sedation using the odds ratio product, a validated ... ...

Abstract	Evaluation of sleep quality in critically ill patients is difficult using conventional scoring criteria. The aim of this study was to examine sleep in critically ill patients with and without light sedation using the odds ratio product, a validated continuous metric of sleep depth (0 = deep sleep; 2.5 = full wakefulness) that does not rely on the features needed for conventional staging. Design: Retrospective study. Settings: A 16-bed medical-surgical ICU. Patients: Twenty-three mechanically ventilated patients who had previously undergone two nocturnal sleep studies, one without and one with sedation (propofol, Interventions: None. Measurements and main results: Sleep architecture was evaluated with odds ratio product analysis by the distribution of 30-second epochs with different odds ratio product values. Electroencephalogram spectral patterns and frequency of wake intrusions (3-s odds ratio product > 1.75) were measured at different odds ratio product levels. Thirty-seven normal sleepers were used as controls. Compared with normal sleepers, unsedated critically ill patients spent little time in stable sleep (percent odds ratio product < 1.0: 31% vs 63%; Conclusions: In stable critically ill unsedated patients, sleep quality is poor with frequent wake intrusions and little stable sleep. Light sedation with propofol or dexmedetomidine resulted in a shift in sleep architecture toward normal in most, but not all, patients.
Language	English
Publishing date	2021-08-10
Publishing country	United States
Document type	Journal Article
ISSN	2639-8028
ISSN (online)	2639-8028
DOI	10.1097/CCE.0000000000000503
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Article ; Online: The role of mother-infant bond in neonatal abstinence syndrome (NAS) management.

Kondili, Elvita / Duryea, Daniel G

Archives of psychiatric nursing

2019 Volume 33, Issue 3, Page(s) 267–274

Abstract: The opioid crisis affects pregnant women and their infants. In the past two decades, the number of infants born with neonatal abstinence syndrome (NAS) has quadrupled causing the cost of healthcare expenditures to climb sharply. Pharmacological and non- ... ...

Abstract	The opioid crisis affects pregnant women and their infants. In the past two decades, the number of infants born with neonatal abstinence syndrome (NAS) has quadrupled causing the cost of healthcare expenditures to climb sharply. Pharmacological and non-pharmacological approaches are recommended for the management of NAS. Despite the attention NAS has recently received, treatment recommendations are limited to the hospital setting with much less focus on discharge planning. Additionally, the literature on NAS management does not consider research promoting mother-infant attachment. Recently, more emphasis has been placed on taking a holistic approach to NAS management. However, scholarly writings and research in this area are scarce. This article provides a review of current literature on NAS management and attachment-based interventions. Recommendations for practice and future research focused on holistic, non-pharmacological approaches to NAS management are provided.
MeSH term(s)	Female ; Humans ; Infant, Newborn ; Mother-Child Relations/psychology ; Neonatal Abstinence Syndrome/therapy ; Object Attachment ; Pregnancy
Language	English
Publishing date	2019-02-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	639197-7
ISSN	1532-8228 ; 0883-9417
ISSN (online)	1532-8228
ISSN	0883-9417
DOI	10.1016/j.apnu.2019.02.003
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Article ; Online: Sleep Architecture Patterns in Critically Ill Patients and Survivors of Critical Illness: A Retrospective Study.

Georgopoulos, Dimitris / Kondili, Eumorfia / Gerardy, Beth / Alexopoulou, Christina / Bolaki, Maria / Younes, Magdy

Annals of the American Thoracic Society

2023 Volume 20, Issue 11, Page(s) 1624–1632

Abstract: Rationale: ...

Abstract	Rationale:
MeSH term(s)	Humans ; Critical Illness ; Retrospective Studies ; Sleep ; Polysomnography/methods ; Survivors ; Intensive Care Units
Language	English
Publishing date	2023-11-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	2717461-X
ISSN	2325-6621 ; 1943-5665 ; 2325-6621
ISSN (online)	2325-6621 ; 1943-5665
ISSN	2325-6621
DOI	10.1513/AnnalsATS.202301-038OC
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