LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 452

Search options

  1. Book ; Online ; E-Book: Inborn errors of immunity

    Aghamohammadi, Asghar / Abolhassani, Hassan / Rezaei, Nima / Yazdani, Reza

    a practical guide

    2021  

    Author's details editor-in-chief: Asghar Aghamohammadi, Hassan Abolhassani ; associate editors: Nima Rezaei, Reza Yazdani
    Keywords Electronic books
    Language English
    Size 1 Online-Ressource (xix, 374 Seiten), Illustrationen, Diagramme
    Publisher Elsevier Academic Press
    Publishing place London
    Publishing country Great Britain
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020903562
    ISBN 978-0-12-823189-0 ; 9780128210284 ; 0-12-823189-0 ; 0128210281
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Book ; Online ; E-Book: Primary immunodeficiency diseases

    Rezaei, Nima / Aghamohammadi, Asghar / Notarangelo, Luigi D.

    definition, diagnosis, and management

    2017  

    Author's details Nima Rezaei, Asghar Aghamohammadi, Luigi D. Notarangelo editors
    Keywords Agammaglobulinemia ; Antibody Deficiencies ; Autoimmunity ; Autoinflammatory Disorders ; B-cell immunodeficiency ; Combined Immunodeficiencies ; Dendritic Cell Deficiencies ; Genetic Defects ; Immunology ; Infectious Complications ; Monocyte Deficiencies ; Phagocyte Defects ; T-Cell Immunodeficiency ; Treatment
    Language English
    Size 1 Online-Ressource (xvii, 582 Seiten), Illustrationen
    Edition Second edition
    Publisher Springer
    Publishing place Berlin
    Publishing country Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019283766
    ISBN 978-3-662-52909-6 ; 9783662529072 ; 3-662-52909-2 ; 3662529076
    DOI 10.1007/978-3-662-52909-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: Primary Immunodeficiency Diseases in Iran: Past, Present and Future.

    Aghamohammadi, Asghar / Abolhassani, Hassan / Rezaei, Nima

    Archives of Iranian medicine

    2021  Volume 24, Issue 2, Page(s) 118–124

    Abstract: Clinical immunology and its subset topics are rather newly emerging medical fields in Iran as well as other developing countries. Primary immunodeficiency diagnosis and treatment were revolutionized in the late 1970s; a period of time that coincided with ...

    Abstract Clinical immunology and its subset topics are rather newly emerging medical fields in Iran as well as other developing countries. Primary immunodeficiency diagnosis and treatment were revolutionized in the late 1970s; a period of time that coincided with the establishment of the Division of Clinical Immunology and Allergy at the Children's Medical Center, Tehran. Subsequently, the launch of fellowship training programs (in 1988), the development of a national Iranian Primary Immunodeficiency Diseases Registry (in 1999), the inauguration of Research Center for Immunodeficiencies (in 2009), and recently, the national primary immunodeficiency network (in 2016) significantly changed the picture of disease management during the last 40 years. In this review, we seek to elucidate the most important past events, current challenges and future directions regarding the field of primary immunodeficiency.
    MeSH term(s) Humans ; Iran ; Primary Immunodeficiency Diseases/therapy ; Registries ; Research/statistics & numerical data ; Research/trends
    Language English
    Publishing date 2021-02-01
    Publishing country Iran
    Document type Journal Article ; Review
    ZDB-ID 2204979-4
    ISSN 1735-3947 ; 1029-2977
    ISSN (online) 1735-3947
    ISSN 1029-2977
    DOI 10.34172/aim.2021.18
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6228: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Primary Immunodeficiency and Thrombocytopenia.

    Mohtashami, Maryam / Razavi, Azadehsadat / Abolhassani, Hassan / Aghamohammadi, Asghar / Yazdani, Reza

    International reviews of immunology

    2021  Volume 41, Issue 2, Page(s) 135–159

    Abstract: Primary immunodeficiency (PID) or Inborn errors of immunity (IEI) refers to a heterogeneous group of disorders characterized by immune system impairment. Although patients with IEI manifest highly variable symptoms, the most common clinical ... ...

    Abstract Primary immunodeficiency (PID) or Inborn errors of immunity (IEI) refers to a heterogeneous group of disorders characterized by immune system impairment. Although patients with IEI manifest highly variable symptoms, the most common clinical manifestations are recurrent infections, autoimmunity and malignancies. Some patients present hematological abnormality including thrombocytopenia due to different pathogenic mechanisms. This review focuses on primary and secondary thrombocytopenia as a complication, which can occur in IEI. Based on the International Union of Immunological Societies phenotypic classification for IEI, the several innate and adaptive immunodeficiency disorders can lead to thrombocytopenia. This review, for the first time, describes manifestation, mechanism and therapeutic modalities for thrombocytopenia in different classes of IEI.
    MeSH term(s) Autoimmunity ; Humans ; Immunologic Deficiency Syndromes ; Thrombocytopenia
    Language English
    Publishing date 2021-01-19
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 632825-8
    ISSN 1563-5244 ; 1545-5858 ; 0883-0185
    ISSN (online) 1563-5244 ; 1545-5858
    ISSN 0883-0185
    DOI 10.1080/08830185.2020.1868454
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2156: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Application of Flow Cytometry in Predominantly Antibody Deficiencies.

    Yazdani, Reza / Aghamohammadi, Asghar / Rezaei, Nima

    Endocrine, metabolic & immune disorders drug targets

    2020  Volume 21, Issue 4, Page(s) 647–663

    Abstract: Predominantly antibody deficiencies (PADs) are a heterogeneous group of primary immunodeficiency disorders (PIDs), consisting of recurrent infections, autoimmunity, inflammation, and other immune complications. In the recent years, several immunological ... ...

    Abstract Predominantly antibody deficiencies (PADs) are a heterogeneous group of primary immunodeficiency disorders (PIDs), consisting of recurrent infections, autoimmunity, inflammation, and other immune complications. In the recent years, several immunological and genetic defects have been recognized in PADs. Currently, 45 distinct PAD disorders with 40 different genetic defects have been identified based on the 2019 IUIS classification. Genetic analysis is helpful for diagnosing PIDs; however, genetic studies are expensive, time-consuming, and unavailable everywhere. Flow cytometry is a highly sensitive tool for evaluating the immune system and diagnosing PADs. In addition to cell populations and subpopulations assay, flow cytometry can measure cell surface, intracellular and intranuclear proteins, biological changes associated with specific immune defects, and certain functional immune abnormalities. These capabilities help in rapid diagnostic and prognostic assessment as well as in evaluating the pathogenesis of PADs. For the first time, this review particularly provides an overview of the application of flow cytometry for diagnosis, immunophenotyping, and determining the pathogenesis of PADs.
    MeSH term(s) Autoimmunity/immunology ; Flow Cytometry/methods ; Humans ; Immunologic Deficiency Syndromes/diagnosis ; Immunologic Deficiency Syndromes/immunology ; Primary Immunodeficiency Diseases/diagnosis ; Primary Immunodeficiency Diseases/immunology
    Language English
    Publishing date 2020-07-21
    Publishing country United Arab Emirates
    Document type Journal Article ; Review
    ZDB-ID 2228325-0
    ISSN 2212-3873 ; 1871-5303
    ISSN (online) 2212-3873
    ISSN 1871-5303
    DOI 10.2174/1871530320666200721013312
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5824: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Comprehensive Assessment of Skin Disorders in Patients with Common Variable Immunodeficiency (CVID).

    Zarezadeh Mehrabadi, Ali / Aghamohamadi, Nazanin / Abolhassani, Hassan / Aghamohammadi, Asghar / Rezaei, Nima / Yazdani, Reza

    Journal of clinical immunology

    2022  Volume 42, Issue 3, Page(s) 653–664

    Abstract: Background: Common variable immunodeficiency (CVID) is an inborn error of immunity (IEI) characterized by various clinical manifestations such as hypogammaglobulinemia, recurrent infections, and autoimmune diseases. Among different clinical ... ...

    Abstract Background: Common variable immunodeficiency (CVID) is an inborn error of immunity (IEI) characterized by various clinical manifestations such as hypogammaglobulinemia, recurrent infections, and autoimmune diseases. Among different clinical manifestations, skin manifestations have been less reported in these patients.
    Methods: In this study, we investigated the prevalence of dermatologic features in 387 CVID patients. Demographic information, clinical manifestations, laboratory data, and genetic findings were collected from medical records. All data were analyzed based on the presence or absence of skin disorders in CVID patients.
    Results: We observed at least one skin manifestation in about 40% of these patients. Among these complications, skin infection (n = 64, 42.1%) was the most frequent presentation, followed by non-infectious skin lesions (n = 54, 35.6%). Among skin infections, abscesses (n = 34, 22.4%) were the most common complication. Skin infections such as cellulitis, impetigo, measles, and warts were also documented. Eczema (n = 34, 22.4%) was the most common complication in atopic lesions, and vitiligo (n = 13, 8.5%) was prevalent in autoimmune/pigmentation disorders. Among all the patients with genetic mutations, one-quarter had a deleterious mutation in the LRBA gene, relating to the autoimmune and atopic skin lesions.
    Conclusion: This rate of skin disorders in our cohort demonstrating these manifestations could be significant in CVID patients, and they are not rare. Low data of skin complications in CVID patients could be attributed to insufficient attention of physicians and also might alert dermatologists to perform immunological investigations in children with certain skin manifestations.
    MeSH term(s) Adaptor Proteins, Signal Transducing/genetics ; Agammaglobulinemia ; Autoimmune Diseases ; Child ; Common Variable Immunodeficiency/complications ; Common Variable Immunodeficiency/diagnosis ; Common Variable Immunodeficiency/epidemiology ; Humans ; Mutation ; Skin Diseases/diagnosis ; Skin Diseases/epidemiology ; Skin Diseases/etiology
    Chemical Substances Adaptor Proteins, Signal Transducing ; LRBA protein, human (EC 2.7.10.-)
    Language English
    Publishing date 2022-01-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 779361-3
    ISSN 1573-2592 ; 0271-9142
    ISSN (online) 1573-2592
    ISSN 0271-9142
    DOI 10.1007/s10875-022-01211-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1640: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Are asthma and allergic diseases phenotypic markers for patients with common variable immunodeficiency?

    Fekrvand, Saba / Abolhassani, Hassan / Delavari, Samaneh / Yazdani, Reza / Aghamohammadi, Asghar

    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology

    2020  Volume 124, Issue 6, Page(s) 636

    MeSH term(s) Asthma ; Biomarkers ; Common Variable Immunodeficiency ; Humans ; Hypersensitivity
    Chemical Substances Biomarkers
    Language English
    Publishing date 2020-03-23
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1228189-x
    ISSN 1534-4436 ; 0003-4738 ; 1081-1206
    ISSN (online) 1534-4436
    ISSN 0003-4738 ; 1081-1206
    DOI 10.1016/j.anai.2020.03.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.136: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Clinical complications and their management in a child with ataxia‐telangiectasia (A‐T)

    Marzieh Heidarzadeh Arani / Reza ArefNezhad / Javad Fathgharib / Asghar Aghamohammadi / Hossein Motedayyen

    Clinical Case Reports, Vol 9, Iss 1, Pp 556-

    A case report study

    2021  Volume 559

    Abstract: Abstract Ataxia‐telangiectasia (A‐T) is known as an uncommon autosomal recessive disorder associated with recurrent infections and other clinical complications. The management of its complications can improve life quality of patients. ...

    Abstract Abstract Ataxia‐telangiectasia (A‐T) is known as an uncommon autosomal recessive disorder associated with recurrent infections and other clinical complications. The management of its complications can improve life quality of patients.
    Keywords ataxia‐telangiectasia ; recurrent pneumonia ; The ataxia‐telangiectasia mutated (ATM) gene ; Medicine ; R ; Medicine (General) ; R5-920
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: Histocompatibility Complex Status and Mendelian Randomization Analysis in Unsolved Antibody Deficiency.

    Abolhassani, Hassan / Lim, Che Kang / Aghamohammadi, Asghar / Hammarström, Lennart

    Frontiers in immunology

    2020  Volume 11, Page(s) 14

    Abstract: The pathogenesis in the majority of patients with common variable immunodeficiency (CVID), the most common symptomatic primary immunodeficiency, remains unknown. We aimed to compare the minor and major histocompatibility complex (MHC) markers as well as ... ...

    Abstract The pathogenesis in the majority of patients with common variable immunodeficiency (CVID), the most common symptomatic primary immunodeficiency, remains unknown. We aimed to compare the minor and major histocompatibility complex (MHC) markers as well as polygenic scores of common genetic variants between patients with monogenic CVID and without known genetic mutation detected. Monogenic patients were identified in a CVID cohort using whole exome sequencing. Computational full-resolution MHC typing and confirmatory PCR amplicon-based high-resolution typing were performed. Exome-wide polygenic scores were developed using significantly different variants and multi-variant Mendelian randomization (MR) analyses were used to test the causality of significant genetic variants on antibody levels and susceptibility to infectious diseases. Among 83 CVID patients (44.5% females), monogenic defects were found in 40 individuals. Evaluation of the remaining CVID patients without known genetic mutation detected showed 13 and 27 significantly associated MHC-class I and II alleles, respectively. The most significant partial haplotype linked with the unsolved CVID was W
    MeSH term(s) Adolescent ; Adult ; Alleles ; Child ; Child, Preschool ; Cohort Studies ; Common Variable Immunodeficiency/genetics ; Common Variable Immunodeficiency/immunology ; Female ; Genes, MHC Class I/genetics ; Genes, MHC Class II/genetics ; Genetic Predisposition to Disease ; Haplotypes ; Humans ; Male ; Mendelian Randomization Analysis/methods ; Mutation ; Phenotype ; Polymorphism, Single Nucleotide ; Whole Exome Sequencing ; Young Adult
    Language English
    Publishing date 2020-01-24
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2020.00014
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article: Clinical complications and their management in a child with ataxia-telangiectasia (A-T): A case report study.

    Heidarzadeh Arani, Marzieh / ArefNezhad, Reza / Fathgharib, Javad / Aghamohammadi, Asghar / Motedayyen, Hossein

    Clinical case reports

    2020  Volume 9, Issue 1, Page(s) 556–559

    Abstract: Ataxia-telangiectasia (A-T) is known as an uncommon autosomal recessive disorder associated with recurrent infections and other clinical complications. The management of its complications can improve life quality of patients. ...

    Abstract Ataxia-telangiectasia (A-T) is known as an uncommon autosomal recessive disorder associated with recurrent infections and other clinical complications. The management of its complications can improve life quality of patients.
    Language English
    Publishing date 2020-11-29
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.3581
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top