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Article ; Online: Single use of psychoactive substances and its association with sleep disorders and sleep health in a large US college sample.

Qeadan, Fares / Beaudin, Stephane / Reutrakul, Sirimon / English, Kevin

Journal of American college health : J of ACH

2024 , Page(s) 1–15

Abstract: Objective: Estimate the association between single (i.e., exclusive) use of a range of substances and sleep outcomes.: Participants: College students participated in the 2015-2019 American College-Health Association-National College-Health Assessment ...

Abstract	Objective: Estimate the association between single (i.e., exclusive) use of a range of substances and sleep outcomes. Participants: College students participated in the 2015-2019 American College-Health Association-National College-Health Assessment survey. Methods: Multivariable logistic and linear regressions were used. Results: Single users of sedative, opioid, tobacco, and stimulant drugs were more likely to report a diagnosis of insomnia and other sleep disorder and indicated more days per week of negative sleep health outcomes compared not only to non-users of these substances but also polysubstance users. Single users of alcohol were significantly less likely to report a diagnosis of sleep disorder and indicated having had more days per week of positive sleep health outcomes compared to non-alcohol users and polysubstance users. However, those results are reversed for binge drinking. Conclusions: Support of programs addressing behaviors to reduce the high prevalence of psychoactive substance use and sleep disturbances in college youth is needed.
Language	English
Publishing date	2024-03-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	604907-2
ISSN	1940-3208 ; 0744-8481
ISSN (online)	1940-3208
ISSN	0744-8481
DOI	10.1080/07448481.2024.2317171
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Article ; Online: The risk of opioid use disorder among women undergoing obstetric-related procedures

Fares Qeadan / Benjamin Tingey / Nana Akofua Mensah

Drug and Alcohol Dependence Reports, Vol 10, Iss , Pp 100210- (2024)

Results from the Cerner Real-World Database

1481

Abstract: Introduction: While the relationship between various obstetric procedures and the onset of opioid use disorder (OUD) remains ambiguous, this study aims to elucidate the immediate and prolonged risks of OUD in women who have undergone procedures such as ... ...

Abstract	Introduction: While the relationship between various obstetric procedures and the onset of opioid use disorder (OUD) remains ambiguous, this study aims to elucidate the immediate and prolonged risks of OUD in women who have undergone procedures such as vaginal and cesarean deliveries, induced abortions, and treatments related to miscarriages and ectopic pregnancies. Methods: Retrospective data (n = 632,872) from the Cerner Real-World Data™ for pregnant females (age 15–44) between January 2010 and March 2020 were used. Adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were used to compare odds of OUD for each obstetric outcome to normal vaginal delivery using multivariable logistic regression. New opioid prescriptions and persistent opioid prescriptions were secondary outcomes for which modified Poisson regression models were used. Results: Compared to patients with a vaginal delivery, those with an ectopic pregnancy, a cesarean delivery, miscarriage, and an induced abortion had 84%, 46%, 119%, and 131% significantly higher odds of OUD (aOR [95% CI]: 1.84 [1.36, 2.48], 1.46 [1.29, 1.65], 2.19 [1.94, 2.47], and 2.31 [1.80, 2.96]) respectively. Among opioid naïve patients, all other obstetric procedure groups (besides miscarriage) had significantly higher risk of being prescribed new opioids than those with a vaginal delivery. Among those newly prescribed opioids, patients from all other obstetric procedure groups demonstrated a significantly higher risk of persistent opioid prescription compared to those who had a vaginal delivery. Conclusion: The association between specific obstetric outcomes, notably miscarriage and induced abortions, and opioid use patterns should inform safer and more effective pain management in a maternal population.
Keywords	Delivery modes ; Obstetric procedures ; OUD ; Persistent opioids ; Medicine ; R
Subject code	610
Language	English
Publishing date	2024-03-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Using the Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST) to Predict Gambling Disorder Among U.S. College Students.

Qeadan, Fares / Egbert, Jamie / Tingey, Benjamin / Plum, Abigail / Pasewark, Tatiana

Journal of gambling studies

2024

Abstract: The Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST) screening tool has not previously been used to evaluate risk for gambling disorder (GD). We aimed to assess the level at which each specific substance involvement score (SSIS), ... ...

Abstract	The Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST) screening tool has not previously been used to evaluate risk for gambling disorder (GD). We aimed to assess the level at which each specific substance involvement score (SSIS), measured by ASSIST, most optimally predicted GD among U.S. college students. Data were analyzed for 141,769 students from the National College Health Assessment (fall 2019-spring 2021) utilizing multivariable logistic regression models. Sensitivities and specificities were utilized to find optimal cutoffs that best identified those with GD, overall and by biological sex and age group. Lower threshold of substance risk related to prescription opioids, cocaine, and hallucinogens (all with SSIS cutoffs of 4) predicts gambling disorder compared to sedatives (SSIS cutoff of 19). Younger students had lower thresholds of substance risk predicting GD than older students for heroin, but for all other substance classifications students 25 years and older had lower thresholds of SSIS predicting GD than students 18-24 years old. This study aids in the understanding that substance use behavior may put students at risk for other addictive behaviors such as GD. This study is the first to utilize the ASSIST tool to predict GD among U.S. college students, extending its application beyond substance use disorders. The identification of optimal cutoffs for each SSIS provides a novel approach to concurrently screen for GD and substance use disorders. This unique contribution could enhance early detection and intervention strategies for GD in the college student population.
Language	English
Publishing date	2024-02-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2016895-0
ISSN	1573-3602 ; 1050-5350
ISSN (online)	1573-3602
ISSN	1050-5350
DOI	10.1007/s10899-024-10283-w
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Article ; Online: The risk of opioid use disorder among women undergoing obstetric-related procedures: Results from the Cerner Real-World Database.

Qeadan, Fares / Tingey, Benjamin / Mensah, Nana Akofua

Drug and alcohol dependence reports

2023 Volume 10, Page(s) 100210

Abstract	Introduction: While the relationship between various obstetric procedures and the onset of opioid use disorder (OUD) remains ambiguous, this study aims to elucidate the immediate and prolonged risks of OUD in women who have undergone procedures such as vaginal and cesarean deliveries, induced abortions, and treatments related to miscarriages and ectopic pregnancies. Methods: Retrospective data ( Results: Compared to patients with a vaginal delivery, those with an ectopic pregnancy, a cesarean delivery, miscarriage, and an induced abortion had 84%, 46%, 119%, and 131% significantly higher odds of OUD (aOR [95% CI]: 1.84 [1.36, 2.48], 1.46 [1.29, 1.65], 2.19 [1.94, 2.47], and 2.31 [1.80, 2.96]) respectively. Among opioid naïve patients, all other obstetric procedure groups (besides miscarriage) had significantly higher risk of being prescribed new opioids than those with a vaginal delivery. Among those newly prescribed opioids, patients from all other obstetric procedure groups demonstrated a significantly higher risk of persistent opioid prescription compared to those who had a vaginal delivery. Conclusion: The association between specific obstetric outcomes, notably miscarriage and induced abortions, and opioid use patterns should inform safer and more effective pain management in a maternal population.
Language	English
Publishing date	2023-12-13
Publishing country	Netherlands
Document type	Journal Article
ISSN	2772-7246
ISSN (online)	2772-7246
DOI	10.1016/j.dadr.2023.100210
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Article ; Online: The Association Between Resiliency Factors and Suicide Indicators Among American Indian/Alaska Native Middle School Students in New Mexico: A Strength-Based Analysis.

Parshall, Carolyn / Qeadan, Fares / Espinoza, Judith / English, Kevin

Public health reports (Washington, D.C. : 1974)

2023 Volume 138, Issue 2_suppl, Page(s) 71S–79S

Abstract: Objective: Suicide is a leading cause of death among American Indian/Alaska Native (AI/AN) young people aged 10-19 years in the United States, but data collection and reporting in this population are lacking. We examined results of an oversample project ...

Abstract	Objective: Suicide is a leading cause of death among American Indian/Alaska Native (AI/AN) young people aged 10-19 years in the United States, but data collection and reporting in this population are lacking. We examined results of an oversample project in New Mexico to determine the association between resiliency factors and suicide-related behaviors among AI/AN middle school students. Methods: We conducted analyses using data from the 2019 New Mexico Youth Risk and Resiliency Survey for students in grades 6 through 8. An oversampling method was used to increase the sample size of AI/AN students. We used logistic regression to determine the association between resiliency factors and suicide indicators among AI/AN students, stratified by sex. Results: Among female AI/AN students, community support had the strongest protective effect against having seriously thought about suicide (adjusted odds ratio [aOR] = 0.23; 95% CI, 0.14-0.38), while family support was significantly associated with the lowest odds of having made a suicide plan (aOR = 0.15; 95% CI, 0.08-0.28) and having attempted suicide (aOR = 0.21; 95% CI, 0.13-0.34) ( Conclusions: Oversampling AI/AN young people can help accurately quantify and understand health risk behaviors and strengths of this population, leading to improved health and wellness. Family, community, and school-based support should be considered in interventions geared toward suicide prevention among AI/AN young people.
MeSH term(s)	Adolescent ; Female ; Humans ; Male ; American Indian or Alaska Native/psychology ; American Indian or Alaska Native/statistics & numerical data ; New Mexico/epidemiology ; Students/psychology ; Students/statistics & numerical data ; Surveys and Questionnaires ; United States/epidemiology ; Resilience, Psychological ; Suicide/ethnology ; Suicide/psychology ; Suicide/statistics & numerical data ; Child ; Young Adult ; Suicidal Ideation ; Suicide, Attempted/ethnology ; Suicide, Attempted/psychology ; Suicide, Attempted/statistics & numerical data ; Social Support/psychology ; Social Support/statistics & numerical data ; School Mental Health Services/statistics & numerical data
Language	English
Publishing date	2023-03-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	120953-x
ISSN	1468-2877 ; 0033-3549
ISSN (online)	1468-2877
ISSN	0033-3549
DOI	10.1177/00333549231156607
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Article ; Online: Eating disorders and substance use: Examining associations among US college students.

Qeadan, Fares / English, Kevin / Luke, Amy / Egbert, Jamie

The International journal of eating disorders

2023 Volume 56, Issue 5, Page(s) 956–968

Abstract: Objective: To investigate associations between reported eating disorder (ED) diagnosis and substance use disorder (SUD) diagnosis, substance misuse, and illicit drug use among US college students.: Method: Data consisting of n = 414,299 students' ... ...

Abstract	Objective: To investigate associations between reported eating disorder (ED) diagnosis and substance use disorder (SUD) diagnosis, substance misuse, and illicit drug use among US college students. Method: Data consisting of n = 414,299 students' responses to the National College Health Assessment survey conducted by the American College Health Association between fall 2015 and spring 2019 were utilized for this study. Unadjusted and adjusted odds ratios were used to determine the association of reported ED diagnosis with reported SUD diagnosis, misuse of cigarettes, e-cigarettes, alcohol, marijuana, cocaine/methamphetamine, sedatives, hallucinogens, opiates, inhalants, MDMA, and other club drugs, as well as illicit use of prescription pain killers, prescription sedatives, and prescription stimulants. A sensitivity analysis investigating associations between reported anorexia nervosa (AN), bulimia nervosa (BN), and each substance use outcome was also conducted. Results: Among all in our analytic cohort, 7.15% reported receiving an ED diagnosis or being treated for an ED in the last 12 months. Students with ED indications were significantly more likely to report each of the substance use outcomes investigated in this study, including SUD diagnosis (aOR: 7.43; 95% CI: 6.98, 7.92; p < .0001), opiate misuse (aOR: 8.35; 95% CI: 7.38, 9.45; p < .0001), and misuse of other club drugs (aOR: 10.37; 95% CI: 9.10, 11.81; p < .0001) than peers without reported EDs. Both AN and BN were associated with an increased likelihood of SUD diagnosis. Discussion: These findings demonstrate strong associations between EDs and the most extensive list of substance use outcomes explored in the context of college setting ED research to date.
MeSH term(s)	Humans ; United States ; Electronic Nicotine Delivery Systems ; Substance-Related Disorders/diagnosis ; Students ; Illicit Drugs ; Hypnotics and Sedatives
Chemical Substances	Illicit Drugs ; Hypnotics and Sedatives
Language	English
Publishing date	2023-01-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	603170-5
ISSN	1098-108X ; 0276-3478
ISSN (online)	1098-108X
ISSN	0276-3478
DOI	10.1002/eat.23892
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Article ; Online: Intersectionality of demographic characteristics in self-reported anorexia nervosa, bulimia nervosa, and probable eating disorders among college students.

Egbert, Jamie / Luke, Amy / Qeadan, Fares

The International journal of eating disorders

2023 Volume 57, Issue 1, Page(s) 132–145

Abstract: Objective: To investigate associations between identity intersectionality, with a primary focus on minority identity, and probable eating disorders (EDs) within the US college student population.: Method: Data consisting of n = 414,299 college ... ...

Abstract	Objective: To investigate associations between identity intersectionality, with a primary focus on minority identity, and probable eating disorders (EDs) within the US college student population. Method: Data consisting of n = 414,299 college students' responses to the American College Health Association's National College Health Assessment between fall 2015 and spring 2019 were utilized for this study. Overall and stratified adjusted odds ratios (aORs) were used to assess the association between different facets of identity (i.e., race/ethnicity, gender identity, and sexual orientation) and probable EDs. Results: Among all, in our analytic sample, 7.15% reported a probable ED. Interactions between all three identity variables were significant, and thus stratified odds ratios were evaluated. Transgender men were significantly more likely to report probable ED than cisgender male peers within the following racial/ethnic groups: non-Hispanic White (aOR: 3.33; 95% CI: 2.79, 3.96; p < .0001), non-Hispanic Black (aOR: 3.29; 95% CI: 1.72, 6.28; p = .0003), Hispanic (aOR: 2.31; 95% CI: 1.55, 3.43; p < .0001), Asian or Pacific Islander (aOR: 2.19; 95% CI: 1.45, 3.30; p = .0002), Biracial or Multicultural (aOR: 3.36; 95% CI: 2.17, 5.22; p < .0001), and other (aOR: 4.19; 95% CI: 2.25, 7.79; p < .0001). Conclusions: This study underscores the importance of increasing our understanding of interactions between marginalized identities and the ways in which minority identity informs ED risk. Public significance: The impact of multiple marginalized identities on ED outcomes is not well understood. Our study expands on previous ACHA-NCHA studies by addressing identity intersectionality, looking at more than one identity at a time (i.e., specifically race/ethnicity, gender identity, and sexual orientation). Our results contribute unique risk profiles for students who identify with multiple marginalized groups. Further, they indicate that that these associations vary based on the compounded effect of the demographic factors considered.
MeSH term(s)	Humans ; Female ; Male ; United States ; Gender Identity ; Bulimia Nervosa ; Anorexia Nervosa ; Self Report ; Intersectional Framework ; Ethnicity ; Students
Language	English
Publishing date	2023-11-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	603170-5
ISSN	1098-108X ; 0276-3478
ISSN (online)	1098-108X
ISSN	0276-3478
DOI	10.1002/eat.24090
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Article ; Online: Associations between naloxone prescribing and opioid overdose among patients with acute and chronic pain conditions.

Qeadan, Fares / Madden, Erin Fanning

Addiction (Abingdon, England)

2021 Volume 117, Issue 2, Page(s) 457–471

Abstract: Aims: To assess whether naloxone prescribing in clinical contexts targeted pain patients most at risk for opioid overdose.: Design: A retrospective cohort study using data from the Health Facts Database.: Setting: Over 600 United States healthcare ...

Abstract	Aims: To assess whether naloxone prescribing in clinical contexts targeted pain patients most at risk for opioid overdose. Design: A retrospective cohort study using data from the Health Facts Database. Setting: Over 600 United States healthcare facilities. Participants: Three patient groups were followed for 2 years during 2009 to 2017: individuals with shoulder or long bone fractures (n = 252 424), chronic pain syndrome (CPS) (n = 76 141), or non-traumatic low back pain (n = 792 956) who received an opioid prescription. Groups were chosen based on previous work. Measurements: The outcome was opioid overdose identified by International Classification of Diseases codes (ICDs) and the primary predictor was number of naloxone prescriptions identified by National Drug Codes (NDCs). Findings: Opioid overdoses occurred among 0.16% of fracture patients (average follow-up time to overdose [AFU] = 240 days), 1.28% of CPS patients (AFU = 244 days), and 0.30% low back pain patients (AFU = 264 days). A total of 58 083 bone fracture patients received naloxone prescriptions, and naloxone prescription was associated with subsequent opioid overdose (hazard ratio [HR] = 1.87, 95% CI = 1.68-2.09), and number of subsequent overdoses (incidence rate ratio [IRR] = 1.89, 95% CI = 1.69-2.12). A total of 19 529 CPS patients received naloxone prescriptions, and naloxone prescription was associated with subsequent opioid overdose (HR = 1.69, 95% CI = 1.61-1.78) and number of subsequent overdoses (IRR = 1.74, 95% CI = 1.67-1.83). A total of 110 608 low back pain patients received naloxone prescriptions, and naloxone prescription was associated with subsequent opioid overdose (HR = 1.33, 95% CI = 1.27-1.40) and number of subsequent overdoses (IRR = 1.35, 95% CI = 1.29-1.41). Conclusions: Receiving a naloxone prescription appears to be associated with increased risk of subsequent opioid overdose among patients with acute and chronic pain, suggesting prescribers often identify patients most in need of naloxone.
MeSH term(s)	Analgesics, Opioid/therapeutic use ; Chronic Pain/drug therapy ; Drug Overdose/drug therapy ; Drug Overdose/epidemiology ; Humans ; Naloxone/therapeutic use ; Narcotic Antagonists/therapeutic use ; Opiate Overdose ; Retrospective Studies ; United States/epidemiology
Chemical Substances	Analgesics, Opioid ; Narcotic Antagonists ; Naloxone (36B82AMQ7N)
Language	English
Publishing date	2021-08-16
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	1141051-6
ISSN	1360-0443 ; 0965-2140
ISSN (online)	1360-0443
ISSN	0965-2140
DOI	10.1111/add.15643
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Article ; Online: Explaining Variability in Electronic Health Record Effort in Primary Care Ambulatory Encounters.

Overhage, J Marc / Qeadan, Fares / Choi, Eun Ho Eunice / Vos, Duncan / Kroth, Philip J

Applied clinical informatics

2024 Volume 15, Issue 2, Page(s) 212–219

Abstract: Background: Electronic health record (EHR) user interface event logs are fast providing another perspective on the value and efficiency EHR technology brings to health care. Analysis of these detailed usage data has demonstrated their potential to ... ...

Abstract	Background: Electronic health record (EHR) user interface event logs are fast providing another perspective on the value and efficiency EHR technology brings to health care. Analysis of these detailed usage data has demonstrated their potential to identify EHR and clinical process design factors related to user efficiency, satisfaction, and burnout. Objective: This study aimed to analyze the event log data across 26 different health systems to determine the variability of use of a single vendor's EHR based on four event log metrics, at the individual, practice group, and health system levels. Methods: We obtained de-identified event log data recorded from June 1, 2018, to May 31, 2019, from 26 health systems' primary care physicians. We estimated the variability in total Active EHR Time, Documentation Time, Chart Review Time, and Ordering Time across health systems, practice groups, and individual physicians. Results: In total, 5,444 physicians (Family Medicine: 3,042 and Internal Medicine: 2,422) provided care in a total of 2,285 different practices nested in 26 health systems. Health systems explain 1.29, 3.55, 3.45, and 3.30% of the total variability in Active Time, Documentation Time, Chart Review Time, and Ordering Time, respectively. Practice-level variability was estimated to be 7.96, 13.52, 8.39, and 5.57%, respectively, and individual physicians explained the largest proportion of the variability for those same outcomes 17.09, 27.49, 17.51, and 19.75%, respectively. Conclusion: The most variable physician EHR usage patterns occurs at the individual physician level and decreases as you move up to the practice and health system levels. This suggests that interventions to improve individual users' EHR usage efficiency may have the most potential impact compared with those directed at health system or practice levels.
MeSH term(s)	Humans ; Electronic Health Records ; Physicians ; Documentation ; Burnout, Professional ; Primary Health Care
Language	English
Publishing date	2024-03-20
Publishing country	Germany
Document type	Journal Article
ISSN	1869-0327
ISSN (online)	1869-0327
DOI	10.1055/s-0044-1782228
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Article ; Online: Adverse childhood experiences and psychotropic medication prescription among cancer patients.

Montague, Rachel / Canning, Sarah Elise / Thielking, Paul / Qeadan, Fares

Journal of psychosocial oncology

2023 , Page(s) 1–15

Abstract: Background: This study aimed at identifying and characterizing adverse childhood experiences (ACEs) in a sample of cancer patients and subsequently evaluating the relationship between ACEs and prescription of psychotropic medication among them. ... ...

Abstract	Background: This study aimed at identifying and characterizing adverse childhood experiences (ACEs) in a sample of cancer patients and subsequently evaluating the relationship between ACEs and prescription of psychotropic medication among them. Individuals with ACEs have a higher risk of mental health conditions and are more likely to be prescribed psychotropic medications. Methods: A sample of 178 adult patients receiving Supportive Oncology & Survivorship (SOS) services at Huntsman Cancer Hospital in Utah was obtained. ACEs and Brief Resilient Coping Scale (BRCS) questionnaires were administered confidentially. A multivariable mixed effect model, adjusting for sex, age, and insurance type while controlling for zip-codes clustering were employed. Results: Compared to the prevalence of ACEs in the general population, from the CDC-Kaiser Permanente ACEs Study, we found no significant difference in the prevalence of people who had experienced an adverse childhood event (ACEs score > = 1) between our study of cancer patients and the CDC-Kaiser study (67.4% vs. 63.6%, Conclusion: A significant proportion of cancer patients have a history of ACEs, and thus trauma-informed care approach is essential during their treatment.
Language	English
Publishing date	2023-12-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	605892-9
ISSN	1540-7586 ; 0734-7332
ISSN (online)	1540-7586
ISSN	0734-7332
DOI	10.1080/07347332.2023.2296040
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