LIVIVO - Search results -

Search results

Result 1 - 10 of total 18293

Search options

Article ; Online: Probe Substrate Dependencies in CYP3A4 Allosteric Inhibition: A Novel Molecular Mechanism Involving F-F' Loop Perturbations.

Wei, Wan / Tang, Lloyd Wei Tat / Verma, Ravi Kumar / Fan, Hao / Chan, Eric Chun Yong

Journal of chemical information and modeling

2024 Volume 64, Issue 6, Page(s) 2058–2067

Abstract: The biochemical basis for substrate dependences in apparent inhibition constant values ( ...

Abstract	The biochemical basis for substrate dependences in apparent inhibition constant values (
MeSH term(s)	Humans ; Cytochrome P-450 CYP3A/metabolism ; Rivaroxaban ; Allosteric Site ; Molecular Dynamics Simulation ; Testosterone/metabolism
Chemical Substances	Cytochrome P-450 CYP3A (EC 1.14.14.1) ; Rivaroxaban (9NDF7JZ4M3) ; Testosterone (3XMK78S47O) ; CYP3A4 protein, human (EC 1.14.14.55)
Language	English
Publishing date	2024-03-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	190019-5
ISSN	1549-960X ; 0095-2338
ISSN (online)	1549-960X
ISSN	0095-2338
DOI	10.1021/acs.jcim.3c01837
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1230: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: "PEEP-Adjusted P/F Ratio" in ARDS - A Call for Further Enhancement of Global Definition.

Palanidurai, Sunitha / Chan, Yiong Huak / Mukhopadhyay, Amartya

American journal of respiratory and critical care medicine

2024

Language	English
Publishing date	2024-03-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	1180953-x
ISSN	1535-4970 ; 0003-0805 ; 1073-449X
ISSN (online)	1535-4970
ISSN	0003-0805 ; 1073-449X
DOI	10.1164/rccm.202308-1428LE
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uh II Zs.80: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Book ; Online: Localized f-electron magnetism in the semimetal Ce3Bi4Au3

Ajeesh, M. O. / Kushwaha, S. K. / Thomas, S. M. / Thompson, J. D. / Chan, M. K. / Harrison, N. / Tomczak, J. M. / Rosa, P. F. S.

2023

Abstract: Ce$_{3}$Bi$_{4}$Au$_{3}$ crystallizes in the same non-centrosymmetric cubic structure as the prototypical Kondo insulator Ce$_{3}$Bi$_{4}$Pt$_{3}$. Here we report the physical properties of Ce$_{3}$Bi$_{4}$Au$_{3}$ single crystals using magnetization, ... ...

Abstract	Ce$_{3}$Bi$_{4}$Au$_{3}$ crystallizes in the same non-centrosymmetric cubic structure as the prototypical Kondo insulator Ce$_{3}$Bi$_{4}$Pt$_{3}$. Here we report the physical properties of Ce$_{3}$Bi$_{4}$Au$_{3}$ single crystals using magnetization, thermodynamic, and electrical-transport measurements. Magnetic-susceptibility and heat-capacity data reveal antiferromagnetic (AFM) order below $T_N=3.2$ K. The magnetic entropy $S_{\rm mag}$ reaches $R$ln2 slightly above $T_N$, which suggests localized $4f$-moments in a doublet ground state. Multiple field-induced magnetic transitions are observed at temperatures below $T_N$, which indicate a complex spin structure with competing interactions. Ce$_{3}$Bi$_{4}$Au$_{3}$ shows semimetallic behavior in electrical resistivity measurements in contrast to the majority of reported Cerium-based 343 compounds. Electrical-resistivity measurements under hydrostatic pressure reveal a slight enhancement of $T_N$ under pressures up to 2.3 GPa, which supports a scenario wherein Ce$_{3}$Bi$_{4}$Au$_{3}$ belongs to the far left of the Doniach phase diagram dominated by Ruderman-Kittel-Kasuya-Yosida (RKKY) interactions. Using realistic many-body simulations, we confirm the semi-metallic electronic structure of Ce$_{3}$Bi$_{4}$Au$_{3}$ and quantitatively reproduce its local moment behavior in the paramagnetic state. Comment: 10 pages, 10 figures
Keywords	Condensed Matter - Strongly Correlated Electrons ; Condensed Matter - Materials Science
Subject code	530
Publishing date	2023-09-05
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Validation of preloaded DMEK donor tissues: a laboratory-based study on endothelial cell viability and comparison of two F-mark inks.

Dhupar, Narisa / AlShaker, Sara / Chai, Jenny / Yan, Judy / Little, Ness / Humphreys, Christine / Chan, Clara C / Ong Tone, Stephan

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie

2024

Abstract: ... and to compare prestamping with 2 different F-mark inks.: Methods: DMEK donor tissues were stripped ... marked with gentian violet dye applied as an F-mark, trephined, stained with trypan blue, and ... Additionally, ECL and the intensity of an F-mark caused by 2 different inks were quantified.: Results ...

Abstract	Objective: To investigate endothelial cell loss (ECL) associated with Descemet membrane endothelial keratoplasty (DMEK) donor tissues preloaded in the DMEK RAPID transport system after 1 and 5 days and to compare prestamping with 2 different F-mark inks. Methods: DMEK donor tissues were stripped, marked with gentian violet dye applied as an F-mark, trephined, stained with trypan blue, and then preloaded into the DMEK RAPID transport system by an eye bank technician. Preloaded DMEK tissues were then unfolded and stained with calcein AM after 1 or 5 days of storage. Tissues were imaged, analyzed for total tissue ECL, and immunostained for corneal endothelium markers zonular occludens-1 and xCD166. Additionally, ECL and the intensity of an F-mark caused by 2 different inks were quantified. Results: Preloaded DMEK tissues displayed an average ECL of 11.9% ± 4.5% (n = 8) at 1 day and 9.9% ± 4.2% (n = 9) at 5 days. No difference was found between the 2 groups. Zonular occludens-1 and activated leukocyte cell adhesion molecule (ALCAM; also know as CD166) staining showed that the corneal endothelial monolayer remained intact on preloaded tissues. On 5-day preloaded DMEK tissues, the average ECL and mean grayscale caused by the Keir Surgical ink F-mark and the Cardinal Health ink F-mark were 4.3% ± 0.8% and 158.5 ± 13.9% and 5.0% ± 1.1% and 142.9% ± 20.0%, respectively. No difference was found between the F-mark inks. Conclusion: Preloaded DMEK donor tissues resulted in an acceptable ECL range after 1 and 5 days of storage and were deemed suitable for transplantation. Both F-mark inks are acceptable for prestamping preloaded DMEK tissues prior to surgical transplantation with comparable ECL and intensities.
Language	English
Publishing date	2024-03-19
Publishing country	England
Document type	Journal Article
ZDB-ID	80091-0
ISSN	1715-3360 ; 0008-4182
ISSN (online)	1715-3360
ISSN	0008-4182
DOI	10.1016/j.jcjo.2024.02.012
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 588: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Heterogeneous nuclear ribonucleoprotein F deficiency in mouse podocyte promotes podocytopathy mediated by methyltransferase-like 14 nuclear translocation resulting in Sirtuin 1 gene inhibition.

Liao, Min-Chun / Lo, Chao-Sheng / Pang, Yu-Chao / Yang, Wen-Xia / Su, Ke / Zhao, Xin-Ping / Miyata, Kana N / Peng, Junzheng / Ingelfinger, Julie R / Chan, John S D / Zhang, Shao-Ling

Translational research : the journal of laboratory and clinical medicine

2024 Volume 267, Page(s) 1–9

Abstract: Heterogeneous nuclear ribonucleoprotein F (HnRNP F) is a key regulator for nucleic acid metabolism ... however, whether HnRNP F expression is important in maintaining podocyte integrity is unclear. Nephroseq analysis ... from a registry of human kidney biopsies was performed. Age- and sex-matched podocyte-specific HnRNP F knockout ...

Abstract	Heterogeneous nuclear ribonucleoprotein F (HnRNP F) is a key regulator for nucleic acid metabolism; however, whether HnRNP F expression is important in maintaining podocyte integrity is unclear. Nephroseq analysis from a registry of human kidney biopsies was performed. Age- and sex-matched podocyte-specific HnRNP F knockout (HnRNP F
MeSH term(s)	Female ; Mice ; Male ; Humans ; Animals ; Podocytes/metabolism ; Sirtuin 1/genetics ; Sirtuin 1/metabolism ; Heterogeneous-Nuclear Ribonucleoprotein Group F-H/genetics ; Heterogeneous-Nuclear Ribonucleoprotein Group F-H/metabolism ; Diabetes Mellitus/metabolism ; Methyltransferases/metabolism
Chemical Substances	Sirtuin 1 (EC 3.5.1.-) ; Heterogeneous-Nuclear Ribonucleoprotein Group F-H ; Methyltransferases (EC 2.1.1.-)
Language	English
Publishing date	2024-01-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	2246684-8
ISSN	1878-1810 ; 1532-6543 ; 1931-5244
ISSN (online)	1878-1810 ; 1532-6543
ISSN	1931-5244
DOI	10.1016/j.trsl.2024.01.002
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ud II Zs 42: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Electrochemical technique to develop surface-controlled polyaniline nano-tulips (PANINTs) on PCL-reinforced chitosan functionalized (CS-f-Fe

Ghimire, Upasana / Kandel, Rupesh / Ko, Sung Won / Adhikari, Jhalak Raj / Kim, Cheol Sang / Park, Chan Hee

International journal of biological macromolecules

2024 Volume 264, Issue Pt 1, Page(s) 130608

Abstract: ... reinforced chitosan functionalized iron oxide nanoparticles (CS-f-Fe ...

Abstract	Bone defects pose significant challenges in orthopedic surgery, often leading to suboptimal outcomes and complications. Addressing these challenges, we employed a three-electrode electrochemical system to fabricate surface-controlled polyaniline nano-tulips (PANINTs) decorated polycaprolactone (PCL) reinforced chitosan functionalized iron oxide nanoparticles (CS-f-Fe
MeSH term(s)	Chitosan/chemistry ; Osteogenesis ; Tissue Scaffolds/chemistry ; Bone Regeneration/physiology ; Electrochemical Techniques ; Tissue Engineering/methods ; Cell Differentiation ; Cell Proliferation ; Polyesters/chemistry ; Aniline Compounds
Chemical Substances	Chitosan (9012-76-4) ; polyaniline ; Polyesters ; Aniline Compounds
Language	English
Publishing date	2024-03-05
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2024.130608
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 2374: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: 18 F-Flutemetamol PET/CT for Transthyretin Amyloid Cardiomyopathy : Timing Matters.

Han, Eun Ji / Sung, Yeoun Eun / Jung, Mi-Hyang / O, Joo Hyun / Youn, Jong-Chan

Clinical nuclear medicine

2022 Volume 47, Issue 12, Page(s) 1074–1076

Abstract: Abstract: We report 18 F-flutemetamol PET/CT finding in an 88-year-old man with cognitive ...

Abstract	Abstract: We report 18 F-flutemetamol PET/CT finding in an 88-year-old man with cognitive impairment and transthyretin amyloid cardiomyopathy. Early phase PET/CT images showed significantly increased myocardial uptake, but there was no myocardial uptake in delayed phase PET/CT images. A dual-time-point amyloid PET/CT imaging may be helpful to diagnose and differentiate subtypes of amyloid cardiomyopathy in patients with suspected cardiac amyloidosis.
MeSH term(s)	Male ; Humans ; Aged, 80 and over ; Positron Emission Tomography Computed Tomography ; Prealbumin ; Positron-Emission Tomography ; Aniline Compounds ; Benzothiazoles ; Amyloidosis ; Amyloid ; Cardiomyopathies/diagnostic imaging
Chemical Substances	flutemetamol (0F3M7032P5) ; Prealbumin ; Aniline Compounds ; Benzothiazoles ; Amyloid
Language	English
Publishing date	2022-10-14
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	197628-x
ISSN	1536-0229 ; 0363-9762
ISSN (online)	1536-0229
ISSN	0363-9762
DOI	10.1097/RLU.0000000000004411
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1276: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Hb Bart's immunochromatographic test result and Hb F level in normal cord blood and in selected haemoglobinopathy cases.

Chan, George / Wong, Jenna / Sami, Viraj

International journal of laboratory hematology

2023 Volume 46, Issue 2, Page(s) 408–410

MeSH term(s)	Humans ; Fetal Blood/chemistry ; Hemoglobins, Abnormal ; Hemoglobinopathies/diagnosis ; alpha-Thalassemia/diagnosis
Chemical Substances	Hemoglobins, Abnormal
Language	English
Publishing date	2023-12-22
Publishing country	England
Document type	Letter
ZDB-ID	2268590-X
ISSN	1751-553X ; 1751-5521 ; 0141-9854
ISSN (online)	1751-553X
ISSN	1751-5521 ; 0141-9854
DOI	10.1111/ijlh.14223
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1499: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Utility of pre-treatment 18 F-fluorodeoxyglucose PET radiomic analysis in assessing nodal involvement in cervical cancer.

Chan, Kit Chi / Perucho, Jose A U / Subramaniam, Rathan M / Lee, Elaine Y P

Nuclear medicine communications

2023 Volume 44, Issue 5, Page(s) 375–380

Abstract: ... on 18 F-fluorodeoxyglucose ( 18 F-FDG) PET/computed tomography (PET/CT) and then quantitatively ... A total of 101 patients with newly diagnosed cervical cancer, who underwent pre-treatment whole-body 18 F ...

Abstract	Objective: Intratumor heterogeneity has prognostic value in cervical cancer, which can be depicted on 18 F-fluorodeoxyglucose ( 18 F-FDG) PET/computed tomography (PET/CT) and then quantitatively characterized by texture features. This study aimed to evaluate the discriminative performance and predictive ability of the texture features in determining lymph node involvement in cervical cancer. Methods: A total of 101 patients with newly diagnosed cervical cancer, who underwent pre-treatment whole-body 18 F-FDG PET/CT imaging were retrospectively recruited. Patients were categorized based on their nodal status. Thirty-five radiomic features together with the maximum standardized uptake value (SUVmax), metabolic tumor volume (MTV) and total lesion glycolysis (TLG) of the primary cervical tumors were extracted. Conventional indices were used to build logistic regression model and texture features were used to build random forest model. The performances for differentiating nodal status were assessed by receiver operating characteristic analysis. Results: Conventional PET indices were significantly higher in patients with nodal involvement compared to those without: SUVmax = 14.22 vs. 10.05; MTV = 57.02 vs. 28.73; TLG = 492.8 vs. 188.8 ( P < 0.05). Nineteen radiomic features describing regional heterogeneity were significantly different between nodal involvements. Area under the curves of the models with conventional indices and PET texture features for discriminating nodal status were 0.72 and 0.76, respectively. Conclusion: PET-derived radiomic features had moderate performance in discriminating nodal involvement in cervical cancer; and they did not outperform model based on conventional indices.
MeSH term(s)	Female ; Humans ; Fluorodeoxyglucose F18/metabolism ; Positron Emission Tomography Computed Tomography/methods ; Uterine Cervical Neoplasms/diagnostic imaging ; Uterine Cervical Neoplasms/therapy ; Uterine Cervical Neoplasms/metabolism ; Retrospective Studies ; Positron-Emission Tomography/methods ; Tumor Burden ; Radiopharmaceuticals
Chemical Substances	Fluorodeoxyglucose F18 (0Z5B2CJX4D) ; Radiopharmaceuticals
Language	English
Publishing date	2023-02-27
Publishing country	England
Document type	Journal Article
ZDB-ID	758141-5
ISSN	1473-5628 ; 0143-3636
ISSN (online)	1473-5628
ISSN	0143-3636
DOI	10.1097/MNM.0000000000001672
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1577: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Frustrated Lewis pair catalyzed C–F activation of α-trifluoromethylstyrenes

Chakyu Richard Chan / Dipendu Mandal / Rowan D. Young

Tetrahedron Chem, Vol 8, Iss , Pp 100050- (2023)

2023

Abstract: A frustrated Lewis pair approach is used for the monoselective C–F activation of α-trifluoromethyl ... styrenes. Selective C–F activation of α-trifluoromethyl styrenes with trispentafluorophenylborane (BCF ...

Abstract	A frustrated Lewis pair approach is used for the monoselective C–F activation of α-trifluoromethyl styrenes. Selective C–F activation of α-trifluoromethyl styrenes with trispentafluorophenylborane (BCF) in partnership with tri(ortho-tolyl)phosphine or 2,4,6-triphenylpyridine (TPPy) generates γ-substituted α,α-difluoropropenyl phosphonium or pyridinium salts (respectively). The ability to further functionalize such products at the α and γ-positions is demonstrated through nucleophilic substitutions and metal catalyzed Suzuki couplings to generate a range of difluoromethyl and 1,1-difluoroolefin products.
Keywords	Organic chemistry ; QD241-441
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED