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  1. Article ; Online: Pediatric Death Due to Myocarditis After Exposure to Cannabis.

    Nappe, Thomas M / Hoyte, Christopher O

    Clinical practice and cases in emergency medicine

    2017  Volume 1, Issue 3, Page(s) 166–170

    Abstract: Since marijuana legalization, pediatric exposures to cannabis have increased.1 To date, pediatric deaths from cannabis exposure have not been reported. The authors report an 11-month-old male who, following cannabis exposure, presented with central ... ...

    Abstract Since marijuana legalization, pediatric exposures to cannabis have increased.1 To date, pediatric deaths from cannabis exposure have not been reported. The authors report an 11-month-old male who, following cannabis exposure, presented with central nervous system depression after seizure, and progressed to cardiac arrest and died. Myocarditis was diagnosed post-mortem and cannabis exposure was confirmed. Given the temporal relationship of these two rare occurrences - cannabis exposure and sudden death secondary to myocarditis in an 11-month-old - as well as histological consistency with drug-induced myocarditis without confirmed alternate causes, and prior reported cases of cannabis-associated myocarditis, a possible relationship exists between cannabis exposure in this child and myocarditis leading to death. In areas where marijuana is commercially available or decriminalized, the authors urge clinicians to preventively counsel parents and to include cannabis exposure in the differential diagnosis of patients presenting with myocarditis.
    Language English
    Publishing date 2017-03-16
    Publishing country United States
    Document type Case Reports
    ISSN 2474-252X
    ISSN (online) 2474-252X
    DOI 10.5811/cpcem.2017.1.33240
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A Case of Cocaine-Induced Uvular Edema.

    Heard, Matthew / McMahon, Kathleen / Nappe, Thomas

    Cureus

    2020  Volume 12, Issue 12, Page(s) e12308

    Abstract: A 26-year-old male presented to the emergency department with a chief complaint of globus sensation and sore throat in the setting of recent cocaine use. On physical examination, he was found to have isolated uvular edema and erythema. After excluding ... ...

    Abstract A 26-year-old male presented to the emergency department with a chief complaint of globus sensation and sore throat in the setting of recent cocaine use. On physical examination, he was found to have isolated uvular edema and erythema. After excluding other potential inciting mechanisms of Quincke's disease, he was treated with anti-inflammatory medication and was observed for any development of airway compromise prior to discharge.
    Language English
    Publishing date 2020-12-26
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.12308
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Left flank pain.

    Nappe, Thomas M / Quinn, Shawn M

    The western journal of emergency medicine

    2015  Volume 16, Issue 2, Page(s) 314–315

    MeSH term(s) Adolescent ; Bronchopulmonary Sequestration/complications ; Bronchopulmonary Sequestration/diagnostic imaging ; Female ; Flank Pain/etiology ; Humans ; Radiography
    Language English
    Publishing date 2015-03
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2375700-0
    ISSN 1936-9018 ; 1936-900X
    ISSN (online) 1936-9018
    ISSN 1936-900X
    DOI 10.5811/westjem.2015.1.25076
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Serotonin syndrome associated with therapeutic metaxalone in a patient with cirrhosis.

    Surmaitis, Ryan M / Nappe, Thomas M / Cook, Matthew D

    The American journal of emergency medicine

    2016  Volume 34, Issue 2, Page(s) 346.e5–6

    MeSH term(s) Aged ; Humans ; Liver Cirrhosis/chemically induced ; Liver Cirrhosis/diagnosis ; Male ; Neuromuscular Agents/adverse effects ; Oxazolidinones/adverse effects ; Serotonin Syndrome/diagnosis ; Serotonin Syndrome/etiology
    Chemical Substances Neuromuscular Agents ; Oxazolidinones ; metaxalone (1NMA9J598Y)
    Language English
    Publishing date 2016-02
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2015.06.043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: The Chikungunya virus: An emerging US pathogen.

    Nappe, Thomas M / Chuhran, Craig M / Johnson, Steven A

    World journal of emergency medicine

    2016  Volume 7, Issue 1, Page(s) 65–67

    Abstract: Background: The Chikungunya (CHIK) virus was recently reported by the CDC to have spread to the United States. We report an early documented case of CHIK from the state of Pennsylvania after a patient recently returned from Haiti in June of 2014.: ... ...

    Abstract Background: The Chikungunya (CHIK) virus was recently reported by the CDC to have spread to the United States. We report an early documented case of CHIK from the state of Pennsylvania after a patient recently returned from Haiti in June of 2014.
    Methods: A 39-year-old man presented to the emergency department complaining of fever, fatigue, polyarthralgias and a diffuse rash for two days. Four days before, he returned from a mission trip to Haiti and reported that four of his accompanying friends had also become ill. A CHIK antibody titer was obtained and it was found to be positive. During his hospital stay, he responded well to supportive care, including anti-inflammatories, intravenous hydration and anti-emetics.
    Results: His condition improved within two days and he was ultimately discharged home.
    Conclusions: Manifestations of CHIK can be similar to Dengue fever, which is transmitted by the same species of mosquito, and occasionally as a co-infection. Clinicians should include Chikungunya virus in their differential diagnosis of patients who present with fever, polyarthralgia and rash with a recent history of travel to endemic areas, including those within the United States.
    Language English
    Publishing date 2016-02-29
    Publishing country China
    Document type Case Reports
    ZDB-ID 2753264-1
    ISSN 1920-8642
    ISSN 1920-8642
    DOI 10.5847/wjem.j.1920-8642.2016.01.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Bedside Ultrasound Evaluation Uncovering a Rare Urological Emergency Secondary to Neurofibromatosis.

    Nappe, Thomas M / Diaz, Leonel / Evans, Elizabeth M

    The western journal of emergency medicine

    2015  Volume 16, Issue 5, Page(s) 756–757

    MeSH term(s) Female ; Humans ; Middle Aged ; Neurofibroma/complications ; Neurofibroma/diagnostic imaging ; Point-of-Care Testing ; Tomography, X-Ray Computed ; Ultrasonography ; Urinary Bladder/diagnostic imaging ; Urinary Bladder Neoplasms/complications ; Urinary Bladder Neoplasms/diagnostic imaging ; Urinary Retention/diagnostic imaging ; Urinary Retention/etiology
    Language English
    Publishing date 2015-09
    Publishing country United States
    Document type Case Reports ; Journal Article ; Video-Audio Media
    ZDB-ID 2375700-0
    ISSN 1936-9018 ; 1936-900X
    ISSN (online) 1936-9018
    ISSN 1936-900X
    DOI 10.5811/westjem.2015.6.27585
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Open Ring Sign Diagnostic of Multiple Sclerosis in the Emergency Department.

    Nappe, Thomas M / Niehaus, Matthew T / Goyke, Terrence E

    The western journal of emergency medicine

    2015  Volume 16, Issue 4, Page(s) 579–780

    MeSH term(s) Adult ; Brain/diagnostic imaging ; Emergency Service, Hospital ; Female ; Humans ; Multiple Sclerosis/cerebrospinal fluid ; Multiple Sclerosis/diagnosis ; Physical Examination ; Tomography, X-Ray Computed
    Language English
    Publishing date 2015-07
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2375700-0
    ISSN 1936-9018 ; 1936-900X
    ISSN (online) 1936-9018
    ISSN 1936-900X
    DOI 10.5811/westjem.2015.4.26314
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: An Atypical Case of Methemoglobinemia due to Self-Administered Benzocaine.

    Nappe, Thomas M / Pacelli, Anthony M / Katz, Kenneth

    Case reports in emergency medicine

    2015  Volume 2015, Page(s) 670979

    Abstract: Acquired methemoglobinemia is an uncommon hemoglobinopathy that results from exposure to oxidizing agents, such as chemicals or medications. Although, as reported in the adult population, it happens most often due to prescribed medication or procedural ... ...

    Abstract Acquired methemoglobinemia is an uncommon hemoglobinopathy that results from exposure to oxidizing agents, such as chemicals or medications. Although, as reported in the adult population, it happens most often due to prescribed medication or procedural anesthesia and not due to easily accessed over-the-counter medications, the authors will describe an otherwise healthy male adult with no known medical history and no prescribed medications, who presented to the emergency department reporting generalized weakness, shortness of breath, headache, dizziness, and pale gray skin. In addition, the patient reported that he also had a severe toothache for several days, which he had been self-treating with an over-the-counter oral benzocaine gel. Ultimately, the diagnosis of methemoglobinemia was made by clinical history, physical examination, and the appearance of chocolate-colored blood and arterial blood gas (ABG) with cooximetry. After 2 mg/kg of intravenous methylene blue was administered, the patient had complete resolution of all signs and symptoms. This case illustrates that emergency physicians should be keenly aware of the potential of toxic hemoglobinopathy secondary to over-the-counter, nonprescribed medications. Discussion with patients regarding the dangers of inappropriate use of these medicines is imperative, as such warnings are typically not evident on product labels.
    Language English
    Publishing date 2015-03-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2684646-9
    ISSN 2090-6498 ; 2090-648X
    ISSN (online) 2090-6498
    ISSN 2090-648X
    DOI 10.1155/2015/670979
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Left Flank Pain

    Nappe, Thomas / Quinn, Shawn M.

    Western Journal of Emergency Medicine, Vol 16, Iss 2, Pp 314-

    2015  Volume 315

    Abstract: ... n/ ... ...

    Abstract n/a
    Keywords left flank ; Medicine ; R ; Medical emergencies. Critical care. Intensive care. First aid ; RC86-88.9
    Language English
    Publishing date 2015-02-01T00:00:00Z
    Publisher eScholarship Publishing, University of California
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Stevens-Johnson syndrome after treatment with azithromycin: an uncommon culprit.

    Nappe, Thomas M / Goren-Garcia, Stephanie L / Jacoby, Jeanne L

    The American journal of emergency medicine

    2016  Volume 34, Issue 3, Page(s) 676.e1–3

    Abstract: Azithromycin is a commonly prescribed antibiotic but is not considered a common etiologic agent for Stevens-Johnson syndrome (SJS). SJS is a dermatologic emergency that occurs within a spectrum of severity and can result in severe morbidity and mortality. ...

    Abstract Azithromycin is a commonly prescribed antibiotic but is not considered a common etiologic agent for Stevens-Johnson syndrome (SJS). SJS is a dermatologic emergency that occurs within a spectrum of severity and can result in severe morbidity and mortality.
    MeSH term(s) Anti-Bacterial Agents/adverse effects ; Azithromycin/adverse effects ; Diagnosis, Differential ; Emergencies ; Humans ; Male ; Middle Aged ; Stevens-Johnson Syndrome/diagnosis ; Stevens-Johnson Syndrome/etiology
    Chemical Substances Anti-Bacterial Agents ; Azithromycin (83905-01-5)
    Language English
    Publishing date 2016-03
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2015.06.039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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