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  1. Article ; Online: High Prevalence of Cochlear Nerve Deficiency in Pediatric Patients With Cochlear Aperture Stenosis.

    Dorismond, Christina / Smetak, Miriam R / Perkins, Elizabeth L / Foust, Alexandra M / Sarma, Asha / Virgin, Frank W

    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

    2024  

    Abstract: Objective: Cochlear nerve deficiency (CND) is a common radiologic finding among unilateral sensorineural hearing loss (USNHL) patients. It is generally detected with magnetic resonance imaging (MRI), which is associated with higher cost, less ... ...

    Abstract Objective: Cochlear nerve deficiency (CND) is a common radiologic finding among unilateral sensorineural hearing loss (USNHL) patients. It is generally detected with magnetic resonance imaging (MRI), which is associated with higher cost, less availability, and possible need for sedation. Therefore, identifying computed tomography (CT) findings, such as cochlear aperture stenosis (CAS), that can reliably predict CND is valuable. Our study aimed to determine the prevalence of CND in pediatric patients with CT-diagnosed CAS.
    Study design: Retrospective study.
    Setting: Tertiary care center.
    Methods: We included pediatric patients diagnosed with CAS on temporal bone CT and with available temporal bone MRI. For each patient, an otolaryngologist and a pediatric neuroradiologist measured the cochlear aperture width on CT to confirm CAS (cochlear aperture < 1.4 mm) and assessed the status of the cochlear nerve on MRI.
    Results: Fifty-five patients, representing 65 ears, had CAS on CT measurement. Median cochlear aperture width in CAS ears was 0.70 mm (interquartile range [IQR]: 0.40-1.05 mm) versus 2.00 mm in non-CAS ears (IQR: 1.80-2.30 mm, P < .001). CND was found in 98.5% (n = 64/65) of CAS ears, while a normal cochlear nerve was found in 1.5% (n = 1/65) of CAS ears.
    Conclusion: CND is highly prevalent among pediatric patients with CAS. This suggests that MRI may not be needed to assess for CND in USNHL patients with CAS, as initial CT may provide sufficient information to determine cochlear implant candidacy. We recommend thoughtful shared decision-making with parents of USNHL patients when determining whether to pursue MRI in the setting of a CAS diagnosis.
    Language English
    Publishing date 2024-04-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 392085-9
    ISSN 1097-6817 ; 0161-6439 ; 0194-5998
    ISSN (online) 1097-6817
    ISSN 0161-6439 ; 0194-5998
    DOI 10.1002/ohn.774
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  2. Article ; Online: Thoracic Imaging Findings of Multisystem Inflammatory Syndrome in Children Associated with COVID-19: What Radiologists Need to Know Now.

    Winant, Abbey J / Blumfield, Einat / Liszewski, Mark C / Kurian, Jessica / Foust, Alexandra M / Lee, Edward Y

    Radiology. Cardiothoracic imaging

    2020  Volume 2, Issue 4, Page(s) e200346

    Abstract: The coronavirus disease 2019 (COVID-19) global pandemic is an ongoing public health emergency, with over 4 million confirmed cases worldwide. Due to the novel nature of this coronavirus and our evolving understanding of its pathophysiology, there is ... ...

    Abstract The coronavirus disease 2019 (COVID-19) global pandemic is an ongoing public health emergency, with over 4 million confirmed cases worldwide. Due to the novel nature of this coronavirus and our evolving understanding of its pathophysiology, there is continued uncertainty surrounding diagnosis and management of COVID-19, especially in pediatric patients. In addition, a new febrile hyperinflammatory Kawasaki-like syndrome (also known as multisystem inflammatory syndrome in children, or MIS-C) has emerged in pediatric patients with temporal association to COVID-19 infection. This review article aims to provide an up-to-date review of the clinical and imaging findings of pediatric MIS-C associated with COVID-19, compared with typical acute pediatric COVID-19 infection, with an emphasis on thoracic imaging findings. Supplemental material is available for this article. © RSNA, 2020.
    Language English
    Publishing date 2020-07-30
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2638-6135
    ISSN (online) 2638-6135
    DOI 10.1148/ryct.2020200346
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  3. Article ; Online: Private Tour Guide to Pediatric Coronavirus Disease of 2019 and Multisystem Inflammatory Syndrome in Children in 10 Minutes: What Thoracic Radiologists Need to Know.

    Foust, Alexandra M / Winant, Abbey J / Restrepo, Ricardo / Liszewski, Mark C / Plut, Domen / Lee, Edward Y

    Journal of thoracic imaging

    2020  Volume 36, Issue 1, Page(s) 24–30

    Abstract: Filtering through the plethora of radiologic studies generated in response to the coronavirus disease of 2019 (COVID-19) pandemic can be time consuming and impractical for practicing thoracic radiologists with busy clinical schedules. To further ... ...

    Abstract Filtering through the plethora of radiologic studies generated in response to the coronavirus disease of 2019 (COVID-19) pandemic can be time consuming and impractical for practicing thoracic radiologists with busy clinical schedules. To further complicate matters, several of the imaging findings in the pediatric patients differ from the adult population. This article is designed to highlight clinically useful information regarding the imaging manifestations of pediatric COVID-19 pneumonia, including findings more unique to pediatric patients, and multisystem inflammatory syndrome in children.
    MeSH term(s) COVID-19/diagnostic imaging ; Child ; Diagnosis, Differential ; Humans ; Pneumonia, Viral/diagnostic imaging ; SARS-CoV-2 ; Systemic Inflammatory Response Syndrome/diagnostic imaging
    Keywords covid19
    Language English
    Publishing date 2020-09-25
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 632900-7
    ISSN 1536-0237 ; 0883-5993
    ISSN (online) 1536-0237
    ISSN 0883-5993
    DOI 10.1097/RTI.0000000000000565
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  4. Article ; Online: Pediatric SARS, H1N1, MERS, EVALI, and Now Coronavirus Disease (COVID-19) Pneumonia: What Radiologists Need to Know.

    Foust, Alexandra M / Winant, Abbey J / Chu, Winnie C / Das, Karuna M / Phillips, Grace S / Lee, Edward Y

    AJR. American journal of roentgenology

    2020  Volume 215, Issue 3, Page(s) 736–744

    Abstract: OBJECTIVE. ...

    Abstract OBJECTIVE.
    MeSH term(s) Adolescent ; Betacoronavirus ; COVID-19 ; Child ; Child, Preschool ; Coronavirus Infections/diagnostic imaging ; Diagnosis, Differential ; Electronic Nicotine Delivery Systems ; Female ; Humans ; Infant ; Influenza A Virus, H1N1 Subtype ; Influenza, Human/diagnostic imaging ; Lung Injury/diagnostic imaging ; Lung Injury/etiology ; Male ; Middle East Respiratory Syndrome Coronavirus ; Pandemics ; Pneumonia, Viral/diagnostic imaging ; Radiography ; SARS Virus ; SARS-CoV-2 ; Severe Acute Respiratory Syndrome/diagnostic imaging ; Vaping/adverse effects ; Young Adult
    Keywords covid19
    Language English
    Publishing date 2020-04-30
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 82076-3
    ISSN 1546-3141 ; 0361-803X ; 0092-5381
    ISSN (online) 1546-3141
    ISSN 0361-803X ; 0092-5381
    DOI 10.2214/AJR.20.23267
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  5. Article ; Online: Practical guide for pediatric pulmonologists on imaging management of pediatric patients with COVID-19.

    Foust, Alexandra M / McAdam, Alexander J / Chu, Winnie C / Garcia-Peña, Pilar / Phillips, Grace S / Plut, Domen / Lee, Edward Y

    Pediatric pulmonology

    2020  Volume 55, Issue 9, Page(s) 2213–2224

    Abstract: Understanding of coronavirus disease 2019 is rapidly evolving with new articles on the subject daily. This flood of articles can be overwhelming for busy practicing clinicians looking for key pieces of information that can be applied in daily practice. ... ...

    Abstract Understanding of coronavirus disease 2019 is rapidly evolving with new articles on the subject daily. This flood of articles can be overwhelming for busy practicing clinicians looking for key pieces of information that can be applied in daily practice. This review article synthesizes the reported imaging findings in pediatric Coronavirus disease 2019 (COVID-19) across the literature, offers imaging differential diagnostic considerations and useful radiographic features to help differentiate these entities from COVID-19, and provides recommendations for requesting imaging studies to evaluate suspected cases of pediatric COVID-19.
    MeSH term(s) COVID-19/diagnostic imaging ; COVID-19 Testing ; Child ; Humans ; Pediatrics ; Practice Guidelines as Topic ; Pulmonologists ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 632784-9
    ISSN 1099-0496 ; 8755-6863
    ISSN (online) 1099-0496
    ISSN 8755-6863
    DOI 10.1002/ppul.24870
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  6. Article: Private Tour Guide to Pediatric Coronavirus Disease of 2019 and Multisystem Inflammatory Syndrome in Children in 10 Minutes: What Thoracic Radiologists Need to Know

    Foust, Alexandra M / Winant, Abbey J / Restrepo, Ricardo / Liszewski, Mark C / Plut, Domen / Lee, Edward Y

    J. thorac imaging

    Abstract: Filtering through the plethora of radiologic studies generated in response to the coronavirus disease of 2019 (COVID-19) pandemic can be time consuming and impractical for practicing thoracic radiologists with busy clinical schedules. To further ... ...

    Abstract Filtering through the plethora of radiologic studies generated in response to the coronavirus disease of 2019 (COVID-19) pandemic can be time consuming and impractical for practicing thoracic radiologists with busy clinical schedules. To further complicate matters, several of the imaging findings in the pediatric patients differ from the adult population. This article is designed to highlight clinically useful information regarding the imaging manifestations of pediatric COVID-19 pneumonia, including findings more unique to pediatric patients, and multisystem inflammatory syndrome in children.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #873163
    Database COVID19

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  7. Article: Dual-energy CT cisternography in the evaluation of CSF leaks: A novel approach.

    Foust, Alexandra M / Nguyen, Xuan V / Prevedello, Luciano / Bourekas, Eric C / Boulter, Daniel J

    Radiology case reports

    2017  Volume 13, Issue 1, Page(s) 237–240

    Abstract: Cerebrospinal fluid leaks pose a serious threat to patients as they represent an unchecked communication between the subarachnoid space and the extracranial environment. Accurate localization of the leakage site is essential for treatment planning. We ... ...

    Abstract Cerebrospinal fluid leaks pose a serious threat to patients as they represent an unchecked communication between the subarachnoid space and the extracranial environment. Accurate localization of the leakage site is essential for treatment planning. We describe the novel utilization of dual-energy computed tomography technology in cisternography in the evaluation of a patient with a cerebrospinal fluid leak.
    Language English
    Publishing date 2017-10-13
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2406300-9
    ISSN 1930-0433
    ISSN 1930-0433
    DOI 10.1016/j.radcr.2017.09.005
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  8. Article ; Online: Radiographic assessment of traction-induced esophageal growth and traction-related complications of the Foker process for treatment of long-gap esophageal atresia.

    Foust, Alexandra M / Zendejas, Benjamin / Mohammed, Somala / Meisner, Jay / Zurakowski, David / Staffa, Steven J / Jennings, Russell W / Hamilton, Thomas E / Callahan, Michael J

    Pediatric radiology

    2021  Volume 52, Issue 3, Page(s) 468–476

    Abstract: Background: Radiographic assessment of esophageal growth in long-gap esophageal atresia while on traction and associated traction-related complications have not been described.: Objective: To demonstrate how chest radiography can estimate esophageal ... ...

    Abstract Background: Radiographic assessment of esophageal growth in long-gap esophageal atresia while on traction and associated traction-related complications have not been described.
    Objective: To demonstrate how chest radiography can estimate esophageal position while on traction and to evaluate radiography's utility in diagnosing certain traction system complications.
    Materials and methods: In this retrospective evaluation of portable chest radiographs obtained in infants with long-gap esophageal atresia who underwent the Foker process between 2014 and 2020, we assessed distances between the opposing trailing clips (esophageal gap) and the leading and trailing clips for each esophageal segment on serial radiographs. Growth during traction was estimated using longitudinal random-effects regression analysis to account for multiple chest radiograph measurements from the same child.
    Results: Forty-three infants (25 male) had a median esophageal gap of 4.5 cm. Median traction time was 14 days. Median daily radiographic esophageal growth rate for both segments was 2.2 mm and median cumulative growth was 23.6 mm. Traction-related complications occurred in 13 (30%) children with median time of 8 days from traction initiation. Daily change >12% in leading-to trailing clip distance demonstrated 86% sensitivity and 92% specificity for indicating traction-related complications (area under the curve [AUC] 0.853). Cumulative change >30% in leading- to trailing-clip distance during traction was 85% sensitive and 85% specific for indicating traction complications (AUC 0.874).
    Conclusion: Portable chest radiograph measurements can serve as a quantitative surrogate for esophageal segment position in long-gap esophageal atresia. An increase of >12% between two sequential chest radiographs or >30% increase over the traction period in leading- to trailing-clip distance is highly associated with traction system complications.
    MeSH term(s) Anastomosis, Surgical ; Child ; Esophageal Atresia/diagnostic imaging ; Humans ; Infant ; Male ; Retrospective Studies ; Traction
    Language English
    Publishing date 2021-11-30
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 124459-0
    ISSN 1432-1998 ; 0301-0449
    ISSN (online) 1432-1998
    ISSN 0301-0449
    DOI 10.1007/s00247-021-05228-z
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    Zs.A 927: Show issues Location:
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  9. Article ; Online: Dual-Energy CT-Derived Iodine Content and Spectral Attenuation Analysis of Metastatic Versus Nonmetastatic Lymph Nodes in Squamous Cell Carcinoma of the Oropharynx.

    Foust, Alexandra M / Ali, Rukya M / Nguyen, Xuan V / Agrawal, Amit / Prevedello, Luciano M / Bourekas, Eric C / Boulter, Daniel J

    Tomography (Ann Arbor, Mich.)

    2018  Volume 4, Issue 2, Page(s) 66–71

    Abstract: The presence of a single nodal metastasis has significant prognostic and treatment implications for patients with head and neck cancer. This study aims to investigate whether dual-energy computed tomography (DECT)-derived iodine content and spectral ... ...

    Abstract The presence of a single nodal metastasis has significant prognostic and treatment implications for patients with head and neck cancer. This study aims to investigate whether dual-energy computed tomography (DECT)-derived iodine content and spectral attenuation curve analysis can improve detection of nodal metastasis in oropharyngeal carcinoma. Eight patients with newly diagnosed oropharyngeal squamous cell carcinoma and pathologically proven nodal metastatic disease (n = 13 metastatic nodes; n = 16 nonmetastatic nodes) who underwent contrast-enhanced DECT of the neck were retrospectively evaluated. DECT-derived iodine content (mg/mL) and monoenergetic attenuation values at 40 keV and 100 keV were obtained via circular regions of interest within metastatic and nonmetastatic cervical lymph nodes. Iodine content was significantly lower in metastatic nodes (0.96 ± 0.28 mg/mL) than in nonmetastatic nodes (1.65 ± 0.38 mg/mL;
    Language English
    Publishing date 2018-09-10
    Publishing country United States
    Document type Journal Article
    ISSN 2379-139X
    ISSN (online) 2379-139X
    DOI 10.18383/j.tom.2018.00009
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  10. Article ; Online: Practical guide for pediatric pulmonologists on imaging management of pediatric patients with COVID‐19

    Foust, Alexandra M. / McAdam, Alexander J. / Chu, Winnie C. / Garcia‐Peña, Pilar / Phillips, Grace S. / Plut, Domen / Lee, Edward Y.

    Pediatric Pulmonology

    2020  Volume 55, Issue 9, Page(s) 2213–2224

    Keywords Pediatrics, Perinatology, and Child Health ; Pulmonary and Respiratory Medicine ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    ZDB-ID 632784-9
    ISSN 1099-0496 ; 8755-6863
    ISSN (online) 1099-0496
    ISSN 8755-6863
    DOI 10.1002/ppul.24870
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