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Article ; Online: Methemoglobinemia induced by dapsone in a pediatric patient: case report.

Burgos, Ana Clara / Santos, Alexandre Neves da Rocha / Colleti Junior, José / Troster, Eduardo Juan

Critical care science

2023 Volume 35, Issue 2, Page(s) 233–235

MeSH term(s)	Humans ; Child ; Dapsone/adverse effects ; Methemoglobinemia/chemically induced
Chemical Substances	Dapsone (8W5C518302)
Language	Portuguese
Publishing date	2023-11-01
Publishing country	Brazil
Document type	Case Reports ; Letter
ISSN	2965-2774
ISSN (online)	2965-2774
DOI	10.5935/2965-2774.20230018-en
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Article ; Online: The cellular landscape of the endochondral bone during the transition to extrauterine life.

Rueda, Alejandro Díaz / Salvador-Martínez, Irepan / Sospedra-Arrufat, Ismael / Alcaina-Caro, Ana / Fernández-Miñán, Ana / Burgos-Ruiz, Ana M / Cases, Ildefonso / Mohedano, Alberto / Tena, Juan J / Heyn, Holger / Lopez-Rios, Javier / Nusspaumer, Gretel

Immunology and cell biology

2024 Volume 102, Issue 2, Page(s) 131–148

Abstract: The cellular complexity of the endochondral bone underlies its essential and pleiotropic roles during organismal life. While the adult bone has received significant attention, we still lack a deep understanding of the perinatal bone cellulome. Here, we ... ...

Abstract	The cellular complexity of the endochondral bone underlies its essential and pleiotropic roles during organismal life. While the adult bone has received significant attention, we still lack a deep understanding of the perinatal bone cellulome. Here, we have profiled the full composition of the murine endochondral bone at the single-cell level during the transition from fetal to newborn life and in comparison with the adult tissue, with particular emphasis on the mesenchymal compartment. The perinatal bone contains different fibroblastic clusters with blastema-like characteristics in organizing and supporting skeletogenesis, angiogenesis and hematopoiesis. Our data also suggest dynamic inter- and intra-compartment interactions, as well as a bone marrow milieu that seems prone to anti-inflammation, which we hypothesize is necessary to ensure the proper program of lymphopoiesis and the establishment of central and peripheral tolerance in early life. Our study provides an integrative roadmap for the future design of genetic and cellular functional assays to validate cellular interactions and lineage relationships within the perinatal bone.
MeSH term(s)	Mice ; Animals ; Osteogenesis/genetics ; Mesenchymal Stem Cells ; Bone and Bones ; Bone Marrow ; Hematopoiesis
Language	English
Publishing date	2024-01-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	284057-1
ISSN	1440-1711 ; 0818-9641
ISSN (online)	1440-1711
ISSN	0818-9641
DOI	10.1111/imcb.12718
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Article ; Online: Tongue necrosis secondary to giant cell arteritis.

Cantón De Seoane, Juan / Gutiérrez Guédez, Luis Alberto / Rodríguez Cambrón, Ana Belén / Burgos, Fernando

BMJ case reports

2023 Volume 16, Issue 5

Abstract: Tongue necrosis is a rare clinical finding because of its rich vascularisation. Giant cell arteritis (GCA) is the most frequent cause of it, and when present, it is usually one side affected. We describe a patient with several months of constitutional ... ...

Abstract	Tongue necrosis is a rare clinical finding because of its rich vascularisation. Giant cell arteritis (GCA) is the most frequent cause of it, and when present, it is usually one side affected. We describe a patient with several months of constitutional syndrome; during that period, she develops headache followed by tongue necrosis, which lead to clinical suspicion of GCA, later confirmed by a temporal artery biopsy. Before the biopsy, she was treated with corticosteroids. We discuss this illness and tongue necrosis as a rare manifestation to consider.
MeSH term(s)	Female ; Humans ; Giant Cell Arteritis/complications ; Giant Cell Arteritis/diagnosis ; Giant Cell Arteritis/drug therapy ; Necrosis/pathology ; Tongue Diseases/etiology ; Tongue Diseases/complications ; Temporal Arteries/pathology ; Biopsy/adverse effects ; Tongue/pathology
Language	English
Publishing date	2023-05-16
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1757-790X
ISSN (online)	1757-790X
DOI	10.1136/bcr-2023-254888
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Article ; Online: Spanish adaptation of the Stillbirth Stigma Scale (SSS).

Fernández-Alcántara, Manuel / Esteban-Burgos, Ana Alejandra / Escribano, Silvia / Congost-Maestre, Nereida / Pollock, Danielle / Cabañero-Martínez, María José

Death studies

2024 , Page(s) 1–8

Abstract: The death of a baby in the perinatal period is considered a disenfranchized grief that can be a source of significant symptoms of guilt, shame, and stigma. There is a lack of validated instruments for assessing the stigma associated with perinatal grief. ...

Abstract	The death of a baby in the perinatal period is considered a disenfranchized grief that can be a source of significant symptoms of guilt, shame, and stigma. There is a lack of validated instruments for assessing the stigma associated with perinatal grief. The aim of this study was to examine the psychometric properties (factor structure, reliability, and validity) of the Spanish version of the Stillbirth Stigma Scale (SSS) in parents who have experienced a perinatal loss. A total of 291 participants (mostly mothers) completed an online questionnaire that included the SSS and other measures. The best-fitting factor structure was a second-order model with four dimensions and adequate reliability values. In terms of validity, we found statistically significant relationships between the SSS scores and the variables of self-esteem, complicated grief, event centrality, depression, and anxiety. In conclusion, the Spanish adaptation of the SSS is deemed to have adequate psychometric properties.
Language	English
Publishing date	2024-02-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	632596-8
ISSN	1091-7683 ; 0748-1187
ISSN (online)	1091-7683
ISSN	0748-1187
DOI	10.1080/07481187.2024.2312378
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Article ; Online: Spanish adaptation of the perinatal grief intensity scale.

Fernández-Alcántara, Manuel / Madrid-Valero, Juan José / Esteban-Burgos, Ana Alejandra / Congost-Maestre, Nereida / Oliver-Roig, Antonio / Cabañero-Martínez, María José

Journal of reproductive and infant psychology

2024 , Page(s) 1–12

Abstract: Aims/background: Assessing the intensity of perinatal grief is very important for identifying the more complex cases in mothers and fathers. Despite this, there are few assessment tools available. The aim of this study was to analyse the psychometric ... ...

Abstract	Aims/background: Assessing the intensity of perinatal grief is very important for identifying the more complex cases in mothers and fathers. Despite this, there are few assessment tools available. The aim of this study was to analyse the psychometric properties (factorial structure, reliability, and validity) of the Spanish version of the Perinatal Grief Intensity Scale (PGIS). Design/methods: An online survey was completed by 291 mothers and fathers who had suffered perinatal loss in the previous six years. Results: The results showed adequate fit indexes for the three-factor model of the PGIS: reality, confront others, and congruence. Reliability values for the overall scale and subscales were adequate. Finally, with regard to validity, significant ( Conclusion: In conclusion, the Spanish adaptation of the PGIS has adequate reliability and validity scores and a factorial structure consistent with the original version.
Language	English
Publishing date	2024-03-14
Publishing country	England
Document type	Journal Article
ZDB-ID	639124-2
ISSN	1469-672X ; 0264-6838
ISSN (online)	1469-672X
ISSN	0264-6838
DOI	10.1080/02646838.2024.2328049
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Article ; Online: Potentially inappropriate prescriptions and potential prescription omissions in older people living with HIV.

Fernández-Fradejas, Jorge / Delgado-Silveira, Eva / González-Burgos, Elena / Álvarez-Díaz, Ana María / Vélez-Díaz-Pallarés, Manuel

HIV medicine

2024

Abstract: Objectives: This study aimed to determine the prevalence of potentially inappropriate prescriptions (PIPs) and potential prescription omissions (PPOs) in a Spanish cohort of people living with HIV (PLWH) aged ≥65 years and to identify risk factors for ... ...

Abstract	Objectives: This study aimed to determine the prevalence of potentially inappropriate prescriptions (PIPs) and potential prescription omissions (PPOs) in a Spanish cohort of people living with HIV (PLWH) aged ≥65 years and to identify risk factors for the presence of PIPs and PPOs. Methods: This retrospective cross-sectional study was conducted across 10 public hospitals in the Autonomous Community of Madrid, Spain. Clinical and demographic data were cross-checked against hospital and community pharmacy dispensation registries. PIPs and PPOs were assessed using the American Geriatrics Society (AGS)/Beers and Screening Tool of Older Persons' Prescriptions (STOPP)/Screening Tool to Alert Doctors to Right Treatment (START) criteria. Risk factors for PIPs and PPOs and agreement between AGS/Beers and STOPP/START criteria were statistically analysed. Results: This study included 313 PLWH (median age 72 years), of whom 80.5% were men. PIP prevalence rates were 29.4% and 44.4% based on the AGS/Beers and STOPP criteria, respectively. The concordance between AGS/Beers and STOPP criteria was moderate. Benzodiazepines and proton pump inhibitors were the chronic comedications most commonly involved in PIPs. PPOs were observed in 61.4% of the patients. The leading omissions were insufficient influenza and pneumococcal vaccine coverage and inadequate bone health-related treatments. The number of chronic comedications, female sex, neuropsychiatric disorders, and cancer diagnosis were risk factors for PIPs, whereas osteopenia and osteoporosis were risk factors for PPOs. Conclusions: A high prevalence of PIPs and PPOs was observed in our cohort of older PLWH. These findings emphasize the importance of comprehensive medication reviews in this population to reduce inappropriate medication use and address their specific and underserved therapeutic needs.
Language	English
Publishing date	2024-01-23
Publishing country	England
Document type	Journal Article
ZDB-ID	2001932-4
ISSN	1468-1293 ; 1464-2662
ISSN (online)	1468-1293
ISSN	1464-2662
DOI	10.1111/hiv.13616
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Article ; Online: Impacto de la diabetes en el riesgo cardiovascular en pacientes con dislipidemia.

Peña-Rodríguez, Gregorio / Gallardo-Hernández, Ana G / Llerena-García, Cindy G / Maldonado-Burgos, Martha A / Escobedo-Naurisa, Eloísa

Archivos de cardiologia de Mexico

2024 Volume 94, Issue 2, Page(s) 161–168

Abstract: Objective: To determine the impact of diabetes on cardiovascular risk in patients with dyslipidemia.: Method: Observational, cross-sectional and comparative study in which cardiovascular risk was determined at 10 years in 100 patients with ... ...

Title translation	Impact of diabetes on cardiovascular risk in patients with dyslipidemia.
Abstract	Objective: To determine the impact of diabetes on cardiovascular risk in patients with dyslipidemia. Method: Observational, cross-sectional and comparative study in which cardiovascular risk was determined at 10 years in 100 patients with dyslipidemia, of these, 50 non-diabetic patients and 50 diabetic patients. Results: Both groups had similar characteristics in terms of age, blood pressure figures, average body mass index, and HDL and LDL levels. It was observed that the diabetic group has almost double the risk compared to the dyslipidemia group, 13.7 vs. 7.9 (p = 0.014), and the calculated heart age is also higher in patients with diabetes, 80 vs. 66 years (p = 0.003). Even in patients with diabetes there is a greater difference between the real age and the age of the heart, 24 years vs. 15 years of patients without diabetes (p = 0.000). Conclusion: Having diabetes and dyslipidemia doubles the cardiovascular risk of patients. Little metabolic control was found in the population studied, which significantly increases complications at an early age and the economic burden on the health system and the families of patients, so it is necessary to rethink treatment strategies to improve metabolic control and with it the prognosis for the patient in the long term.
Language	Spanish
Publishing date	2024-02-12
Publishing country	Mexico
Document type	English Abstract ; Journal Article
ZDB-ID	2059019-2
ISSN	1665-1731 ; 1665-1731
ISSN (online)	1665-1731
ISSN	1665-1731
DOI	10.24875/ACM.23000042
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Article: A comparison between neurological clinical signs, cerebrospinal fluid analysis, cross-sectional CNS imaging, and infectious disease testing in 168 dogs with infectious or immune-mediated meningoencephalomyelitis from Brazil.

Bach, Fernando Swiech / Cray, Carolyn / Burgos, Ana Paula / Junior, José Ademar Villanova / Montiani-Ferreira, Fabiano

Frontiers in veterinary science

2023 Volume 10, Page(s) 1239106

Abstract: This retrospective study evaluated canine patients with presumptively diagnosed meningoencephalomyelitis (ME) based on neurological clinical signs, cerebrospinal fluid (CSF) analysis, cross-sectional imaging, and infectious disease testing with a limited ...

Abstract	This retrospective study evaluated canine patients with presumptively diagnosed meningoencephalomyelitis (ME) based on neurological clinical signs, cerebrospinal fluid (CSF) analysis, cross-sectional imaging, and infectious disease testing with a limited neurological-focused polymerase chain reaction (PCR) panel performed on blood and CSF. The first goal was to determine the proportion of dogs where the condition was caused by an infectious agent versus a probable immune-mediated etiology (i.e., meningoencephalomyelitis of unknown origin; MUO) in our geographic region. The secondary goals of this study were to examine and define associations between abnormal CSF test results and cross-sectional neuroimaging findings, in addition to defining the age and most common neurological clinical signs in each group of ME. A total of 168 dogs matched the inclusion criteria with magnetic resonance imaging (MRI) performed in 130 dogs and computed tomography (CT) performed in 38 dogs. Presumptive MUO was observed in 152/168 (90.5%) of dogs and infectious ME was identified in 16/168 (9.5%) of dogs (
Language	English
Publishing date	2023-10-25
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2834243-4
ISSN	2297-1769
ISSN	2297-1769
DOI	10.3389/fvets.2023.1239106
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Article ; Online: Contribuciones a una teoría de la innovación rural

Ana Laura Burgos / Gerardo Bocco

Cuadernos de Economía, Vol 39, Iss

2020 Volume 79

Abstract: La importancia de la innovación como clave para el crecimiento económico impulsó una sólida teoría de la innovación de corte neo-schumpeteriano. Esta teoría, sin embargo, es inapropiada para abordar procesos de innovación en áreas rurales rezagadas. Este ...

Abstract	La importancia de la innovación como clave para el crecimiento económico impulsó una sólida teoría de la innovación de corte neo-schumpeteriano. Esta teoría, sin embargo, es inapropiada para abordar procesos de innovación en áreas rurales rezagadas. Este trabajo presenta bases para construir una Teoría de la Innovación Rural (TIR) a partir de: 1) definición del objeto, 2) planteamiento de preguntas clave, 3) un modelo de conocimiento, 4) métodos de construcción teórica, 5) capacidad de anticipación, y 6) expectativas y marco ético. La construcción de una TIR como la propuesta constituye un gran aporte al diseño de políticas públicas y estrategias que orienten el cambio rural desde la perspectiva del desarrollo territorial endógeno.
Keywords	cambio rural ; innovación social ; territorios rurales ; desarrollo endógeno ; construcción de teorías ; Social Sciences ; H ; Economic history and conditions ; HC10-1085
Language	English
Publishing date	2020-01-01T00:00:00Z
Publisher	Universidad Nacional de Colombia
Document type	Article ; Online
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Article ; Online: Prevalence of increased alcohol use and alcohol use disorders in adult victims of terrorist attacks: a systematic and meta-analytic review.

Sanz, Jesús / Hernández-Martínez, Timanfaya / Castillo-Burgos, Patricia / Sanz-García, Ana / García-Vera, María Paz

The American journal of drug and alcohol abuse

2023 Volume 49, Issue 6, Page(s) 705–722

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	Adult ; Humans ; Alcohol Drinking/epidemiology ; Alcoholism ; Prevalence ; Stress Disorders, Post-Traumatic/epidemiology ; Terrorism
Language	English
Publishing date	2023-12-11
Publishing country	England
Document type	Journal Article ; Meta-Analysis ; Review ; Systematic Review ; Research Support, Non-U.S. Gov't
ZDB-ID	193086-2
ISSN	1097-9891 ; 0095-2990
ISSN (online)	1097-9891
ISSN	0095-2990
DOI	10.1080/00952990.2023.2275526
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