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Article ; Online: Navigating the New Reality: A Review of the Epidemiological, Clinical, and Microbiological Characteristics of

Ashkenazi-Hoffnung, Liat / Rosenberg Danziger, Chen

2023 Volume 9, Issue 2

Abstract: During the past decade, ...

Abstract	During the past decade,
Language	English
Publishing date	2023-01-28
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2784229-0
ISSN	2309-608X ; 2309-608X
ISSN (online)	2309-608X
ISSN	2309-608X
DOI	10.3390/jof9020176
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Some children with congenital cytomegalovirus may benefit from additional imaging in addition to ultrasound.

Snapiri, Ori / Danziger, Chen Rosenberg / Kornreich, Liora / Zacks, Nimrod / Bilavsky, Efraim

Acta paediatrica (Oslo, Norway : 1992)

2023 Volume 112, Issue 8, Page(s) 1764–1765

MeSH term(s)	Humans ; Child ; Pregnancy ; Female ; Cytomegalovirus ; Cytomegalovirus Infections/diagnostic imaging ; Cytomegalovirus Infections/congenital ; Ultrasonography ; Pregnancy Complications, Infectious
Language	English
Publishing date	2023-05-17
Publishing country	Norway
Document type	Journal Article
ZDB-ID	203487-6
ISSN	1651-2227 ; 0365-1436 ; 0803-5253
ISSN (online)	1651-2227
ISSN	0365-1436 ; 0803-5253
DOI	10.1111/apa.16820
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Article ; Online: Transient Cardiac Injury in Adolescents Receiving the BNT162b2 mRNA COVID-19 Vaccine.

Snapiri, Ori / Rosenberg Danziger, Chen / Shirman, Nina / Weissbach, Avichai / Lowenthal, Alexander / Ayalon, Itay / Adam, Dganit / Yarden-Bilavsky, Havatzelet / Bilavsky, Efraim

The Pediatric infectious disease journal

2022 Volume 40, Issue 10, Page(s) e360–e363

Abstract: Background: Vaccines are paramount in the effort to end the coronavirus disease 2019 global epidemic. BNT162b2 is approved for the vaccination of adolescents over 16 years of age. Systemic adverse events were scarce though the pretested cohort of this ... ...

Abstract	Background: Vaccines are paramount in the effort to end the coronavirus disease 2019 global epidemic. BNT162b2 is approved for the vaccination of adolescents over 16 years of age. Systemic adverse events were scarce though the pretested cohort of this age group was relatively small. The aim of the current study is to raise awareness for potential adverse reactions. Methods: This is a case series of patients diagnosed with perimyocarditis following vaccination. Patients were compiled from 3 pediatric medical centers in Israel through a network of pediatricians and data regarding those cases was collected. In addition, incidence of perimyocarditis during the vaccination period was compared with previous years. Results: All patients were males 16-18 years old, of Jewish descent, who presented with chest pain that began 1-3 days following vaccination (mean, 2.1 days). In 6 of the 7 patients, symptoms began following the 2nd dose and in 1 patient following the 1st dose. All cases were mild and none required cardiovascular or respiratory support. The incidence of perimyocarditis during the vaccination period was elevated in comparison to previous years. Conclusions: This case series describes a time association between coronavirus disease 2019 vaccine and perimyocarditis in adolescents. All cases were mild, although only long-term follow-up can reveal the true impact of this cardiac injury. While it seems that the incidence of perimyocarditis during the vaccination campaign period is increased, a more comprehensive data collection on a wider scale should be done. We hope this report will serve as a reminder to report events and allow for analysis of potential adverse reactions.
MeSH term(s)	Adolescent ; BNT162 Vaccine ; COVID-19/immunology ; COVID-19 Vaccines/immunology ; Cohort Studies ; Humans ; Incidence ; Israel ; Male ; SARS-CoV-2/immunology ; Vaccination/methods ; Vaccines, Synthetic/immunology ; mRNA Vaccines
Chemical Substances	COVID-19 Vaccines ; Vaccines, Synthetic ; BNT162 Vaccine (N38TVC63NU)
Language	English
Publishing date	2022-01-31
Publishing country	United States
Document type	Journal Article
ZDB-ID	392481-6
ISSN	1532-0987 ; 0891-3668
ISSN (online)	1532-0987
ISSN	0891-3668
DOI	10.1097/INF.0000000000003235
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Article: Reintroducing OPV in Israel on the journey to global polio eradication – Estimation at a low rate of contraindicated population

Rosenberg Danziger, Chen / Anis, Emilia / Danon, Yehuda L / Gordon, Ethel-Sherry / Grotto, Itamar

Vaccine. 2018 June 18, v. 36, no. 26

2018

Abstract: The 2013 reemergence of wild poliovirus in Israel led to the reinstatement of a routine OPV vaccination. Fearing VAPP in immunocompromised, the MOH regulated contraindications for vaccination candidates and household contacts. In this study we estimate ... ...

Abstract	The 2013 reemergence of wild poliovirus in Israel led to the reinstatement of a routine OPV vaccination. Fearing VAPP in immunocompromised, the MOH regulated contraindications for vaccination candidates and household contacts. In this study we estimate the size of the contraindicated population to OPV vaccination.We studied vaccination candidates aged 2–9 and 14–23 months and probable household contacts. Using the rate of contraindications extracted for each study group from a medical records database, a statistical model was built to estimate the probability of contraindications in candidates.3.9% of the 2–9-month-old study group and 4% of the 14–23-month-old group had contraindications by either self or household contacts.A statistical model can provide an estimation of the contraindicated population and can be used in the future when devising vaccination campaigns. In contrast to concerns raised by the MOH, our findings show a smaller than anticipated contraindicated population.
Keywords	databases ; Enterovirus C ; medical records ; probability ; statistical models ; vaccination ; vaccines ; Israel
Language	English
Dates of publication	2018-0618
Size	p. 3717-3720.
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	605674-x
ISSN	1873-2518 ; 0264-410X
ISSN (online)	1873-2518
ISSN	0264-410X
DOI	10.1016/j.vaccine.2018.05.047
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Zs.MO 458: Show issues

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Article ; Online: Pediatrician, watch out for corona-phobia.

Rosenberg Danziger, Chen / Krause, Irit / Scheuerman, Oded / Luder, Anthony / Yulevich, Alon / Dalal, Ilan / Grisaru-Soen, Galia / Bilavsky, Efraim

European journal of pediatrics

2020 Volume 180, Issue 1, Page(s) 201–206

Abstract: The current outbreak of COVID-19 raging globally is taking a heavy toll on the adult population, with a rapidly growing number of newly infected and critically ill patients. However, to date, mortality rate among children is low as they mostly suffer ... ...

Abstract	The current outbreak of COVID-19 raging globally is taking a heavy toll on the adult population, with a rapidly growing number of newly infected and critically ill patients. However, to date, mortality rate among children is low as they mostly suffer from a mild disease. Yet, other more routinely encountered childhood diseases do not stand still and continue to be the main share of pediatricians' everyday challenges. Here we describe a case series of routinely seen pediatric diseases with delayed diagnosis due to different aspects of what we call "Corona-phobia". These cases were easily collected within a 1-week period which implies that this is a more widespread phenomenon.In conclusion, this raises the possibility that measures taken to mitigate this pandemic may be more damaging to children overall than the virus itself. We believe that pediatricians as well as policy makers should take this important aspect into consideration. What is Known: • COVID-19 manifests as a mild disease in most children; however, children are an important reservoir and may become spreaders of the disease. • Social distancing and isolation are important tools in mitigating COVID-19 transmission. What is New: • This case series describes 7 cases with delayed diagnosis of every-day pediatric diseases that were not caused by COVID-19 but were highly influenced by different aspects of "Corona-phobia". • Our objective is to highlight the possibility that measures taken to mitigate this pandemic may lead to a substantial delay in the diagnosis of other non-COVID-19 related diseases.
MeSH term(s)	Adolescent ; COVID-19/epidemiology ; Child ; Child, Preschool ; Female ; Humans ; Incidence ; Infant, Newborn ; Male ; Occupational Exposure/adverse effects ; Pandemics ; Pediatricians/psychology ; Phobic Disorders/epidemiology ; Phobic Disorders/etiology ; Phobic Disorders/psychology ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-07-13
Publishing country	Germany
Document type	Journal Article
ZDB-ID	194196-3
ISSN	1432-1076 ; 0340-6199 ; 0943-9676
ISSN (online)	1432-1076
ISSN	0340-6199 ; 0943-9676
DOI	10.1007/s00431-020-03736-y
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Article ; Online: Delayed diagnosis of paediatric appendicitis during the COVID-19 pandemic.

Snapiri, Ori / Rosenberg Danziger, Chen / Krause, Irit / Kravarusic, Dragan / Yulevich, Alon / Balla, Uri / Bilavsky, Efraim

Acta paediatrica (Oslo, Norway : 1992)

2020 Volume 109, Issue 8, Page(s) 1672–1676

Abstract: Aim: To present seven paediatric patients with appendicitis, all with late diagnosis resulting from different aspects of the fear from the current global COVID-19 pandemic.: Methods: Cases were collected from three paediatric surgical wards. ... ...

Abstract	Aim: To present seven paediatric patients with appendicitis, all with late diagnosis resulting from different aspects of the fear from the current global COVID-19 pandemic. Methods: Cases were collected from three paediatric surgical wards. Comparison between complicated appendicitis rates in the COVID-19 era and similar period in previous year was performed. Results: All seven children presented with complicated appendicitis. Main reasons for the delayed diagnosis during the COVID-19 era were parental concern, telemedicine use and insufficient evaluation. Higher complication rates were found during the COVID-19 era compared to similar period in previous year (22% vs 11%, P-value .06). Conclusion: The fear from COVID-19 pandemic may result in delayed diagnosis and higher complication rates in common paediatric medical conditions. We believe caregivers and healthcare providers should not withhold necessary medical care since delay in diagnosis and treatment in these routinely seen medical emergencies may become as big of a threat as COVID-19 itself.
MeSH term(s)	Adolescent ; Appendicitis/diagnosis ; COVID-19 ; Child ; Child, Preschool ; Coronavirus Infections/epidemiology ; Coronavirus Infections/psychology ; Delayed Diagnosis ; Fear ; Female ; Humans ; Israel/epidemiology ; Male ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/psychology
Keywords	covid19
Language	English
Publishing date	2020-06-08
Publishing country	Norway
Document type	Case Reports ; Journal Article
ZDB-ID	203487-6
ISSN	1651-2227 ; 0365-1436 ; 0803-5253
ISSN (online)	1651-2227
ISSN	0365-1436 ; 0803-5253
DOI	10.1111/apa.15376
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Article ; Online: Reintroducing OPV in Israel on the journey to global polio eradication - Estimation at a low rate of contraindicated population.

Rosenberg Danziger, Chen / Anis, Emilia / Gordon, Ethel-Sherry / Grotto, Itamar / Danon, Yehuda L

Vaccine

2018 Volume 36, Issue 26, Page(s) 3717–3720

Abstract: Introduction: The 2013 reemergence of wild poliovirus in Israel led to the reinstatement of a routine OPV vaccination. Fearing VAPP in immunocompromised, the MOH regulated contraindications for vaccination candidates and household contacts. In this ... ...

Abstract	Introduction: The 2013 reemergence of wild poliovirus in Israel led to the reinstatement of a routine OPV vaccination. Fearing VAPP in immunocompromised, the MOH regulated contraindications for vaccination candidates and household contacts. In this study we estimate the size of the contraindicated population to OPV vaccination. Method: We studied vaccination candidates aged 2-9 and 14-23 months and probable household contacts. Using the rate of contraindications extracted for each study group from a medical records database, a statistical model was built to estimate the probability of contraindications in candidates. Results: 3.9% of the 2-9-month-old study group and 4% of the 14-23-month-old group had contraindications by either self or household contacts. Conclusion: A statistical model can provide an estimation of the contraindicated population and can be used in the future when devising vaccination campaigns. In contrast to concerns raised by the MOH, our findings show a smaller than anticipated contraindicated population.
MeSH term(s)	Adolescent ; Adult ; Child ; Child, Preschool ; Contraindications, Drug ; Disease Eradication ; Female ; Humans ; Infant ; Israel/epidemiology ; Male ; Middle Aged ; Models, Statistical ; Poliomyelitis/epidemiology ; Poliomyelitis/prevention & control ; Poliovirus/immunology ; Poliovirus Vaccine, Oral/administration & dosage ; Young Adult
Chemical Substances	Poliovirus Vaccine, Oral
Language	English
Publishing date	2018-06-12
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	605674-x
ISSN	1873-2518 ; 0264-410X
ISSN (online)	1873-2518
ISSN	0264-410X
DOI	10.1016/j.vaccine.2018.05.047
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Article ; Online: Delayed diagnosis of paediatric appendicitis during the COVID‐19 pandemic

Snapiri, Ori / Rosenberg Danziger, Chen / Krause, Irit / Kravarusic, Dragan / Yulevich, Alon / Balla, Uri / Bilavsky, Efraim

Acta Paediatrica

2020 Volume 109, Issue 8, Page(s) 1672–1676

Keywords	Pediatrics, Perinatology, and Child Health ; General Medicine ; covid19
Language	English
Publisher	Wiley
Publishing country	us
Document type	Article ; Online
ISSN	0803-5253
DOI	10.1111/apa.15376
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Delayed diagnosis of paediatric appendicitis during the COVID-19 pandemic

Snapiri, Ori / Rosenberg Danziger, Chen / Krause, Irit / Kravarusic, Dragan / Yulevich, Alon / Balla, Uri / Bilavsky, Efraim

Acta Paediatr

Abstract: AIM: To present seven paediatric patients with appendicitis, all with late diagnosis resulting from different aspects of the fear from the current global COVID-19 pandemic. METHODS: Cases were collected from three paediatric surgical wards. Comparison ... ...

Abstract	AIM: To present seven paediatric patients with appendicitis, all with late diagnosis resulting from different aspects of the fear from the current global COVID-19 pandemic. METHODS: Cases were collected from three paediatric surgical wards. Comparison between complicated appendicitis rates in the COVID-19 era and similar period in previous year was performed. RESULTS: All seven children presented with complicated appendicitis. Main reasons for the delayed diagnosis during the COVID-19 era were parental concern, telemedicine use and insufficient evaluation. Higher complication rates were found during the COVID-19 era compared to similar period in previous year (22% vs 11%, P-value .06). CONCLUSION: The fear from COVID-19 pandemic may result in delayed diagnosis and higher complication rates in common paediatric medical conditions. We believe caregivers and healthcare providers should not withhold necessary medical care since delay in diagnosis and treatment in these routinely seen medical emergencies may become as big of a threat as COVID-19 itself.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #381823
Database	COVID19

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Article: Pediatrician, watch out for corona-phobia

Rosenberg Danziger, Chen / Krause, Irit / Scheuerman, Oded / Luder, Anthony / Yulevich, Alon / Dalal, Ilan / Grisaru-Soen, Galia / Bilavsky, Efraim

Eur. j. pediatr

Abstract	The current outbreak of COVID-19 raging globally is taking a heavy toll on the adult population, with a rapidly growing number of newly infected and critically ill patients. However, to date, mortality rate among children is low as they mostly suffer from a mild disease. Yet, other more routinely encountered childhood diseases do not stand still and continue to be the main share of pediatricians' everyday challenges. Here we describe a case series of routinely seen pediatric diseases with delayed diagnosis due to different aspects of what we call "Corona-phobia". These cases were easily collected within a 1-week period which implies that this is a more widespread phenomenon.In conclusion, this raises the possibility that measures taken to mitigate this pandemic may be more damaging to children overall than the virus itself. We believe that pediatricians as well as policy makers should take this important aspect into consideration. What is Known: â¢ COVID-19 manifests as a mild disease in most children; however, children are an important reservoir and may become spreaders of the disease. â¢ Social distancing and isolation are important tools in mitigating COVID-19 transmission. What is New: â¢ This case series describes 7 cases with delayed diagnosis of every-day pediatric diseases that were not caused by COVID-19 but were highly influenced by different aspects of "Corona-phobia". â¢ Our objective is to highlight the possibility that measures taken to mitigate this pandemic may lead to a substantial delay in the diagnosis of other non-COVID-19 related diseases.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #641137
Database	COVID19

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