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  1. Article ; Online: Reply to: 'Enhancing cervical cancer surveillance: Utilizing inflammatory markers for improved recurrence detection in low-resource settings and a call for prospective multi-centric studies'.

    Bruno, Matteo / Bizzarri, Nicolò / Scambia, Giovanni / Ferrandina, Gabriella

    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

    2024  , Page(s) 108238

    Language English
    Publishing date 2024-03-12
    Publishing country England
    Document type Letter
    ZDB-ID 632519-1
    ISSN 1532-2157 ; 0748-7983
    ISSN (online) 1532-2157
    ISSN 0748-7983
    DOI 10.1016/j.ejso.2024.108238
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Minimally invasive adrenalectomy: a personalized surgical approach in recurrent cervical cancer.

    Rosati, Andrea / Certelli, Camilla / Ferrandina, Gabriella / Fanfani, Francesco / Scambia, Giovanni / Gallotta, Valerio

    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

    2024  

    Language English
    Publishing date 2024-04-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 1070385-8
    ISSN 1525-1438 ; 1048-891X
    ISSN (online) 1525-1438
    ISSN 1048-891X
    DOI 10.1136/ijgc-2023-005241
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Improving single-agent chemoresistance risk identification in gestational trophoblastic neoplasia.

    Ferrandina, Gabriella / Scambia, Giovanni

    The Lancet. Oncology

    2021  Volume 22, Issue 8, Page(s) 1054–1056

    MeSH term(s) Antineoplastic Combined Chemotherapy Protocols ; Drug Resistance, Neoplasm/genetics ; Female ; Gestational Trophoblastic Disease/diagnosis ; Gestational Trophoblastic Disease/drug therapy ; Gestational Trophoblastic Disease/genetics ; Humans ; Pregnancy
    Language English
    Publishing date 2021-06-25
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2049730-1
    ISSN 1474-5488 ; 1470-2045
    ISSN (online) 1474-5488
    ISSN 1470-2045
    DOI 10.1016/S1470-2045(21)00327-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Response to: Correspondence on "Human papillomavirus independent status on pathologic response and outcomes in locally advanced cervical cancer managed with chemoradiotherapy followed by surgery" by Yuce Sari et al.

    Turco, Luigi Carlo / Pedone Anchora, Luigi / Scambia, Giovanni / Ferrandina, Gabriella

    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

    2023  Volume 33, Issue 9, Page(s) 1491–1492

    MeSH term(s) Humans ; Female ; Human Papillomavirus Viruses ; Uterine Cervical Neoplasms/therapy ; Chemoradiotherapy
    Language English
    Publishing date 2023-09-04
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1070385-8
    ISSN 1525-1438 ; 1048-891X
    ISSN (online) 1525-1438
    ISSN 1048-891X
    DOI 10.1136/ijgc-2023-004803
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: In Reply to Govardhan et al.

    Ferrandina, Gabriella

    International journal of radiation oncology, biology, physics

    2015  Volume 93, Issue 1, Page(s) 213–214

    MeSH term(s) Adenocarcinoma/therapy ; Carcinoma, Squamous Cell/therapy ; Chemoradiotherapy, Adjuvant/methods ; Dose Fractionation ; Female ; Humans ; Uterine Cervical Neoplasms/therapy
    Language English
    Publishing date 2015-09-01
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 197614-x
    ISSN 1879-355X ; 0360-3016
    ISSN (online) 1879-355X
    ISSN 0360-3016
    DOI 10.1016/j.ijrobp.2015.04.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: External beam radiotherapy boost versus surgical debulking followed by radiotherapy for the treatment of metastatic lymph nodes in cervical cancer: A systematic review and meta-analysis.

    Bizzarri, Nicolò / Di Berardino, Stefano / Benkortbi, Khadidja / Balaya, Vincent / Gambacorta, Maria Antonietta / Macchia, Gabriella / Boulvain, Michel / Feki, Anis / Mathevet, Patrice / Lecuru, Fabrice / Querleu, Denis / Ferrandina, Gabriella / Scambia, Giovanni / Guani, Benedetta

    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

    2024  Volume 50, Issue 4, Page(s) 108013

    Abstract: Objective: We aimed to assess disease-free survival (DFS), overall survival (OS) and treatment-related toxicity of two therapeutic strategies for treating bulky lymph nodes on imaging in patients with locally advanced cervical cancer (LACC): ... ...

    Abstract Objective: We aimed to assess disease-free survival (DFS), overall survival (OS) and treatment-related toxicity of two therapeutic strategies for treating bulky lymph nodes on imaging in patients with locally advanced cervical cancer (LACC): radiotherapy boost versus surgical debulking followed by radiotherapy.
    Methods: We performed a systematic review of studies published up to October 2023. We selected studies including patients with LACC treated by external beam radiotherapy (EBRT) boost or lymph node debulking followed by EBRT (with or without boost).
    Results: We included two comparative (included in the meta-analysis) and nine non-comparative studies. The estimated 3-year recurrence rate was 28.2% (95%CI:18.3-38.0) in the EBRT group and 39.9% (95%CI:22.1-57.6) in the surgical debulking plus EBRT group. The estimated 3-year DFS was 71.8% and 60.1%, respectively (p = 0.19). The estimated 3-year death rate was 22.2% (95%CI:11.2-33.2) in the EBRT boost group and 31.9% (95%CI:23.3-40.5) in the surgical debulking plus EBRT group. The estimated 3-year OS was 77.8% and 68.1%, respectively (p = 0.04). No difference in lymph node recurrence between the two comparative studies (p = 0.36). The meta-analysis of the two comparative studies showed no DFS difference (p = 0.13) but better OS in the radiotherapy boost group (p = 0.006). The incidence of grade≥3 toxicities (ranging 0-50%) was not different between the two approaches in the two comparative studies (p = 0.31).
    Conclusion: No DFS and toxicity difference when comparing EBRT boost with surgical debulking of enlarged lymph nodes and EBRT in patients with cervical cancer was evident. Radiotherapy boost had better OS. Further investigation is required to better understand the prognostic role of surgical lymph node debulking in light of radiotherapy developments.
    MeSH term(s) Female ; Humans ; Uterine Cervical Neoplasms/radiotherapy ; Uterine Cervical Neoplasms/pathology ; Cytoreduction Surgical Procedures ; Lymph Nodes/pathology ; Brachytherapy ; Disease-Free Survival
    Language English
    Publishing date 2024-02-13
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 632519-1
    ISSN 1532-2157 ; 0748-7983
    ISSN (online) 1532-2157
    ISSN 0748-7983
    DOI 10.1016/j.ejso.2024.108013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Minimally invasive surgery and quality of life in cervical cancer.

    Ferrandina, Gabriella / Corrado, Giacomo / Scambia, Giovanni

    The Lancet. Oncology

    2020  Volume 21, Issue 6, Page(s) 746–748

    MeSH term(s) Female ; Humans ; Hysterectomy ; Minimally Invasive Surgical Procedures ; Quality of Life ; Uterine Cervical Neoplasms/surgery
    Language English
    Publishing date 2020-06-04
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2049730-1
    ISSN 1474-5488 ; 1470-2045
    ISSN (online) 1474-5488
    ISSN 1470-2045
    DOI 10.1016/S1470-2045(20)30161-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: ASO Author Reflections: Minimally Invasive Adjuvant Surgery in Locally Advanced Cervical Cancer: Which Role?

    Federico, Alex / Gallotta, Valerio / Scambia, Giovanni / Ferrandina, Gabriella

    Annals of surgical oncology

    2020  Volume 28, Issue 7, Page(s) 3627–3628

    MeSH term(s) Female ; Humans ; Minimally Invasive Surgical Procedures ; Uterine Cervical Neoplasms/surgery
    Language English
    Publishing date 2020-11-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-020-09320-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Treatment of platinum refractory or resistant ovarian cancer.

    Ferrandina, Gabriella / Corrado, Giacomo

    The Lancet. Oncology

    2018  Volume 19, Issue 9, Page(s) 1147–1149

    MeSH term(s) Double-Blind Method ; Female ; Humans ; Neoplasm Recurrence, Local ; Ovarian Neoplasms ; Platinum ; Sorafenib ; Topotecan
    Chemical Substances Platinum (49DFR088MY) ; Topotecan (7M7YKX2N15) ; Sorafenib (9ZOQ3TZI87)
    Language English
    Publishing date 2018-08-09
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2049730-1
    ISSN 1474-5488 ; 1470-2045
    ISSN (online) 1474-5488
    ISSN 1470-2045
    DOI 10.1016/S1470-2045(18)30428-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A turning point in the fight against ovarian cancer?

    Scambia, Giovanni / Ferrandina, Gabriella

    The Lancet. Oncology

    2018  Volume 19, Issue 2, Page(s) 154–156

    MeSH term(s) Cell Cycle Checkpoints ; Checkpoint Kinase 1 ; Female ; Humans ; Ovarian Neoplasms ; Pyrazines ; Pyrazoles
    Chemical Substances Pyrazines ; Pyrazoles ; prexasertib ; Checkpoint Kinase 1 (EC 2.7.11.1)
    Language English
    Publishing date 2018-01-18
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2049730-1
    ISSN 1474-5488 ; 1470-2045
    ISSN (online) 1474-5488
    ISSN 1470-2045
    DOI 10.1016/S1470-2045(18)30005-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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