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  1. Book: The bedside dysmorphologist

    Reardon, William

    a guide to identifying and assessing congenital malformations

    2016  

    Author's details William Reardon
    Keywords Child ; Congenital Abnormalities / diagnosis ; Infant
    Language English
    Size XXII, 383 S. : zahlr. Ill.
    Edition 2. ed.
    Publisher Oxford Univ. Press
    Publishing place Oxford u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT018823531
    ISBN 978-0-19-997088-9 ; 0-19-997088-2
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2015 A 4059 available for loan (reading room) Lesesaal EG

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  2. Article ; Online: DNA-based assay for calorimetric determination of protein concentrations in pure or mixed solutions.

    Eskew, Matthew W / Reardon, Patrick / Benight, Albert S

    PloS one

    2024  Volume 19, Issue 3, Page(s) e0298969

    Abstract: It was recently reported that values of the transition heat capacities, as measured by differential scanning calorimetry, for two globular proteins and a short DNA hairpin in NaCl buffer are essentially equivalent, at equal concentrations (mg/mL). To ... ...

    Abstract It was recently reported that values of the transition heat capacities, as measured by differential scanning calorimetry, for two globular proteins and a short DNA hairpin in NaCl buffer are essentially equivalent, at equal concentrations (mg/mL). To validate the broad applicability of this phenomenon, additional evidence for this equivalence is presented that reveals it does not depend on DNA sequence, buffer salt, or transition temperature (Tm). Based on the equivalence of transition heat capacities, a calorimetric method was devised to determine protein concentrations in pure and complex solutions. The scheme uses direct comparisons between the thermodynamic stability of a short DNA hairpin standard of known concentration, and thermodynamic stability of protein solutions of unknown concentrations. Sequences of two DNA hairpins were designed to confer a near 20°C difference in their Tm values. In all cases, evaluated protein concentrations determined from the DNA standard curves agreed with the UV-Vis concentration for monomeric proteins. For multimeric proteins evaluated concentrations were greater than determined by UV-Vis suggesting the calorimetric approach can also be an indicator of molecular stoichiometry.
    MeSH term(s) DNA/chemistry ; Calorimetry ; Thermodynamics ; Calorimetry, Differential Scanning ; Proteins ; Sodium Chloride
    Chemical Substances DNA (9007-49-2) ; Proteins ; Sodium Chloride (451W47IQ8X)
    Language English
    Publishing date 2024-03-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0298969
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: The bedside dysmorphologist

    Reardon, William

    classic clinical signs in human malformation syndromes and their diagnostic significance

    2007  

    Author's details William Reardon
    Keywords Pediatrics ; Abnormalities / diagnosis ; Child ; Infant ; Abnormalities, Human/Diagnosis ; Physical diagnosis
    Subject code 616.043
    Language English
    Size 306 S. : zahlr. Ill., 21cm
    Publisher Oxford Univ. Press
    Publishing place Oxford u.a.
    Publishing country Great Britain
    Document type Book
    Note Includes bibliographical references
    HBZ-ID HT015281180
    ISBN 0-19-530045-9 ; 978-0-19-530045-1
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2007 A 5754 order for loan Magazin

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  4. Article: Calorimetric analysis using DNA thermal stability to determine protein concentration.

    Eskew, Matthew W / Reardon, Patrick W / Benight, Albert S

    bioRxiv : the preprint server for biology

    2023  

    Abstract: It was recently reported for two globular proteins and a short DNA hairpin in NaCl buffer that values of the transition heat capacities, ...

    Abstract It was recently reported for two globular proteins and a short DNA hairpin in NaCl buffer that values of the transition heat capacities,
    Language English
    Publishing date 2023-09-26
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.09.25.559360
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Establishing or Excluding a Diagnosis of Fetal Valproate Spectrum Disorder is a Multi-layered Process.

    Kalim, A / Reardon, W

    Irish medical journal

    2021  Volume 114, Issue 6, Page(s) 382

    Abstract: Background In 2017/2018, the Health Products Regulatory Authority issued new guidance on the prescription of Sodium Valproate (VPA) to female patients of reproductive age. A review was initiated of VPA exposed individuals to identify whether previously ... ...

    Abstract Background In 2017/2018, the Health Products Regulatory Authority issued new guidance on the prescription of Sodium Valproate (VPA) to female patients of reproductive age. A review was initiated of VPA exposed individuals to identify whether previously unascertained cases of VPA related Embryopathy could be identified. Methods Forty patients under twenty-three years of age were reviewed. Results Eleven (27.5%) new cases of Fetal Valproate Spectrum Disorder (FVSD) were identified. Twenty-four (60%) cases were felt not to satisfy diagnostic threshold for this teratogenic disorder. Five (12.5%) cases were indeterminate. Six of the forty patients (15%) had an alternative genetic cause of developmental delay established. Conclusion There is increased awareness regarding avoidance of VPA use in women of childbearing age. An equal awareness is warranted that developmental delay in the context of VPA exposure in pregnancy does not necessarily constitute a diagnosis of FVSD but that other competing diagnostic hypotheses have to be considered.
    MeSH term(s) Abnormalities, Drug-Induced/drug therapy ; Anticonvulsants/adverse effects ; Female ; Humans ; Pregnancy ; Valproic Acid/adverse effects
    Chemical Substances Anticonvulsants ; Valproic Acid (614OI1Z5WI)
    Language English
    Publishing date 2021-06-24
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 193134-9
    ISSN 0332-3102 ; 0021-129X
    ISSN 0332-3102 ; 0021-129X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 148: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Nitrogen-fixing bacterial communities differ between perennial agroecosystem crops.

    Sorochkina, Kira / Martens-Habbena, Willm / Reardon, Catherine L / Inglett, Patrick W / Strauss, Sarah L

    FEMS microbiology ecology

    2024  

    Abstract: Biocrusts, common in natural ecosystems, are specific assemblages of microorganisms at or on the soil surface with associated microorganisms extending into the top centimeter of soil. Agroecosystem biocrusts have similar rates of nitrogen (N) fixation as ...

    Abstract Biocrusts, common in natural ecosystems, are specific assemblages of microorganisms at or on the soil surface with associated microorganisms extending into the top centimeter of soil. Agroecosystem biocrusts have similar rates of nitrogen (N) fixation as those in natural ecosystems, but it is unclear how agricultural management influences their composition and function. This study examined the total bacterial and diazotrophic communities of biocrusts in a citrus orchard and a vineyard that shared similar climate and soil type but differed in management. To contrast climate and soil type, these biocrusts were also compared to those from an apple orchard. Unlike natural ecosystem biocrusts, these agroecosystem biocrusts were dominated by proteobacteria and had a lower abundance of cyanobacteria. All examined agroecosystem biocrust diazotroph communities were dominated by N-fixing cyanobacteria from the Nostocales order, similar to natural ecosystem cyanobacterial biocrusts. Lower irrigation and fertilizer in the vineyard compared to the citrus orchard could have contributed to biocrust microbial composition, whereas soil type and climate could have differentiated the apple orchard biocrust. Season did not influence bacterial and diazotrophic community composition of any these agroecosystem biocrusts. Overall, agricultural management and climatic and edaphic factors potentially influenced community composition and function of these biocrusts.
    Language English
    Publishing date 2024-04-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 283722-5
    ISSN 1574-6941 ; 0168-6496
    ISSN (online) 1574-6941
    ISSN 0168-6496
    DOI 10.1093/femsec/fiae064
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2967: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Enhancing Self-Management of Percutaneous Endoscopic Gastrostomy Tubes Through the Implementation of a Standardized Education and Assessment Pathway: A Quality Improvement Initiative.

    Reardon, Joyce / Truax, Alexis-Evelyn / Naranian, Taline / Liu, Louis W C

    Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates

    2023  Volume 46, Issue 1, Page(s) 41–46

    Abstract: Intraduodenal infusion of levodopa-carbidopa intestinal gel by percutaneous endoscopic gastrostomy tube with jejunal extension is a treatment option to reduce motor and nonmotor complications in patients with advanced Parkinson's disease when oral ... ...

    Abstract Intraduodenal infusion of levodopa-carbidopa intestinal gel by percutaneous endoscopic gastrostomy tube with jejunal extension is a treatment option to reduce motor and nonmotor complications in patients with advanced Parkinson's disease when oral therapy no longer provides sufficient benefit. Medication management is of central focus; however, there was no standardized patient education on stoma-site care and tube maintenance, leading to the development of stoma-site complications. As a quality improvement (QI) initiative, a standardized education and assessment pathway was developed and implemented in an urban academic outpatient clinic to enhance patient self-management and reduce stoma-site complications. A retrospective chart review was conducted to establish baseline incidence of cutaneous stoma-site complications. QI interventions were implemented using a rapid-cycle improvement model. Routine stoma assessments by a nurse who specializes in wound, ostomy, and continence care were implemented at set points, and patient education on PEG tube care and maintenance was reinforced at each session. Results demonstrated a significant reduction in moderate-to-severe tube and stoma-site-related complication. Implementation of a similar standardized education and assessment pathway in patients with percutaneous endoscopic gastrostomy tubes may lead to a decrease in stoma-site-related complications and overall better patient self-management.
    MeSH term(s) Humans ; Antiparkinson Agents/adverse effects ; Parkinson Disease ; Gastrostomy/adverse effects ; Gastrostomy/methods ; Retrospective Studies ; Quality Improvement ; Self-Management
    Chemical Substances Antiparkinson Agents
    Language English
    Publishing date 2023-01-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1109536-2
    ISSN 1538-9766 ; 1042-895X
    ISSN (online) 1538-9766
    ISSN 1042-895X
    DOI 10.1097/SGA.0000000000000689
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3422: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Retrospective Comparison of Isolated Haglund's Deformity Surgery Versus Combined With Gastrocnemius Recession.

    Vesely, Bryanna D / Reardon, Brennan K / Scott, Aaron T / Medda, Ashleigh W

    The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons

    2023  Volume 62, Issue 4, Page(s) 719–722

    Abstract: Insertional Achilles tendonitis is a common pathology treated by foot and ankle surgeons that may require surgical intervention. Literature has shown good outcomes following detachment and reattachment of the Achilles for removal of the exostosis. ... ...

    Abstract Insertional Achilles tendonitis is a common pathology treated by foot and ankle surgeons that may require surgical intervention. Literature has shown good outcomes following detachment and reattachment of the Achilles for removal of the exostosis. However, there is minimal literature showing the impact of adding a gastrocnemius recession to the Haglund's resection. The goal of the present study was to retrospectively review the outcomes of an isolated Haglund's resection versus a Haglund's resection combined with a gastrocnemius recession. A retrospective chart review of 54 operative extremities was performed: 29 with isolated Haglund's resection and 25 with a Strayer gastrocnemius recession. We found similar decreases in pain between the 2 groups, 6.1 to 1.5 and 6.8 to 1.8 in the isolated Haglund's and Strayer's group, respectively. We found decreased postoperative Achilles rupture and reoperation rates in the Strayer group but this did not reach statistical significance. We found a statistically significant decreased rate of wound healing complications in the Strayer group, 4% in the Strayer group and 24% in the isolated procedure. In conclusion, adding a Strayer to a Haglund's resection was found to have a statistically significant decrease in wound complications. We recommend future randomized controlled studies to compare the use of a Strayer procedure on postoperative complications.
    MeSH term(s) Humans ; Retrospective Studies ; Calcaneus/surgery ; Calcaneus/pathology ; Heel Spur ; Exostoses ; Achilles Tendon/surgery ; Lower Extremity ; Bursitis/surgery
    Language English
    Publishing date 2023-03-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1146972-9
    ISSN 1542-2224 ; 1067-2516
    ISSN (online) 1542-2224
    ISSN 1067-2516
    DOI 10.1053/j.jfas.2023.03.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1468: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Feasibility and Intermediate Results of Transcarotid Revascularization with a Prosthetic Conduit.

    Cui, Christina L / Reardon, Emily S / Loanzon, Roberto S / Williams, Zachary F / Cox, Mitchell W / Southerland, Kevin W

    Annals of vascular surgery

    2024  Volume 103, Page(s) 74–80

    Abstract: Background: Transcarotid artery revascularization (TCAR) is a hybrid technique with excellent initial outcomes. The technical success and safety of TCAR is heavily dependent on an anatomically suitable common carotid artery (CCA). Many patients do not ... ...

    Abstract Background: Transcarotid artery revascularization (TCAR) is a hybrid technique with excellent initial outcomes. The technical success and safety of TCAR is heavily dependent on an anatomically suitable common carotid artery (CCA). Many patients do not meet anatomic criteria and therefore are not eligible for this therapy. We sought to extend the eligibility of TCAR to patients with unfavorable CCA anatomy via the adoption of a prosthetic arterial conduit.
    Methods: A single-center retrospective study of patients with critical carotid artery stenosis who underwent TCAR via a prosthetic conduit between June 2019 and October 2021 was performed. All patients in the study were considered high-risk for carotid endarterectomy based on anatomic features, such as restenosis post-carotid endarterectomy and neck radiation. Unfavorable CCA anatomy was defined as a clavicle to carotid bifurcation distance <5 cm, a CCA diameter <6 mm, and/or significant atherosclerotic disease at the intended arterial access site. The primary outcome of interest was technical success. Secondary outcomes included perioperative complications, intermediate and long-term patency, intermediate and long-term stroke and/or mortality and in-hospital length of stay. Follow-up ranged from 1 to 29 months.
    Results: Eight patients underwent 10 TCAR procedures via a prosthetic conduit. A total of 2 procedures (20%) were performed on female patients and 8 procedures (75%) were performed on male patients. The mean age was 65 years old (standard deviation 11 years). Technical success was 100%. The 30-day ipsilateral stroke rate was 0%. The 30-day patency was 90%. There was no re-exploration for hemorrhage and 30 day mortality was 0%.
    Conclusions: TCAR is an excellent option for carotid artery revascularization. Unfavorable CCA anatomy has limited its applicability. TCAR via a prosthetic conduit has the potential to expand eligibility for this promising therapy.
    Language English
    Publishing date 2024-02-22
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1027366-9
    ISSN 1615-5947 ; 0890-5096
    ISSN (online) 1615-5947
    ISSN 0890-5096
    DOI 10.1016/j.avsg.2023.12.075
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2882: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Comparing recidivism rates among domestically violent men enrolled in ACTV versus Duluth/CBT.

    Lawrence, Erika / Mazurek, Callie / Reardon, Kathleen W

    Journal of consulting and clinical psychology

    2021  Volume 89, Issue 5, Page(s) 469–475

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Adolescent ; Adult ; Aggression ; Cognitive Behavioral Therapy/statistics & numerical data ; Domestic Violence/statistics & numerical data ; Humans ; Male ; Recidivism/statistics & numerical data ; United States/epidemiology ; Young Adult
    Language English
    Publishing date 2021-06-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 121321-0
    ISSN 1939-2117 ; 0022-006X
    ISSN (online) 1939-2117
    ISSN 0022-006X
    DOI 10.1037/ccp0000649
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 850: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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