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  1. Article ; Online: Penile and generalised calciphylaxis in peritoneal dialysis.

    Sarkis, Edmond

    BMJ case reports

    2015  Volume 2015

    Abstract: This is a rare case of penile and generalised calciphylaxis. We describe the case of a patient admitted to our hospital for septic shock and necrotic skin findings, end-stage renal disease on peritoneal dialysis. Skin findings turned out to be ... ...

    Abstract This is a rare case of penile and generalised calciphylaxis. We describe the case of a patient admitted to our hospital for septic shock and necrotic skin findings, end-stage renal disease on peritoneal dialysis. Skin findings turned out to be calciphyactic lesions. The patient was taken to the operating room for penile debridement and started on antibiotics. He was treated with sodium thiosulfate and switched to haemodialysis. Calciphylaxis is a rare disease in which the treatment is basically supportive. Further studies are needed to identify the risk factors, mechanisms of disease and treatment modalities.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Calciphylaxis/complications ; Calciphylaxis/etiology ; Calciphylaxis/pathology ; Calciphylaxis/prevention & control ; Debridement/methods ; Humans ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/therapy ; Male ; Middle Aged ; Necrosis/drug therapy ; Necrosis/etiology ; Necrosis/surgery ; Penile Diseases/drug therapy ; Penile Diseases/etiology ; Penile Diseases/pathology ; Penile Diseases/surgery ; Peritoneal Dialysis/adverse effects ; Renal Dialysis/methods ; Shock, Septic/etiology ; Thiosulfates/administration & dosage
    Chemical Substances Anti-Bacterial Agents ; Thiosulfates ; sodium thiosulfate (HX1032V43M)
    Language English
    Publishing date 2015-04-16
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2014-209153
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Anti-interleukin (IL)-5 as a steroid-sparing agent in chronic eosinophilic pneumonia.

    Sarkis, Edmond / Patel, Sumit / Burns, Kenneth / Batarseh, Hanan / Mador, M Jeffery

    The Journal of asthma : official journal of the Association for the Care of Asthma

    2018  Volume 57, Issue 1, Page(s) 82–86

    Abstract: ... ...

    Abstract Introduction
    MeSH term(s) Adult ; Antibodies, Monoclonal, Humanized/pharmacology ; Antibodies, Monoclonal, Humanized/therapeutic use ; Chronic Disease/drug therapy ; Drug Therapy, Combination/methods ; Female ; Glucocorticoids/therapeutic use ; Humans ; Interleukin-5/antagonists & inhibitors ; Interleukin-5/immunology ; Lung/diagnostic imaging ; Lung/immunology ; Pulmonary Eosinophilia/diagnosis ; Pulmonary Eosinophilia/drug therapy ; Pulmonary Eosinophilia/immunology ; Recurrence ; Secondary Prevention/methods ; Tomography, X-Ray Computed ; Treatment Outcome
    Chemical Substances Antibodies, Monoclonal, Humanized ; Glucocorticoids ; IL5 protein, human ; Interleukin-5 ; mepolizumab (90Z2UF0E52)
    Language English
    Publishing date 2018-11-16
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 603816-5
    ISSN 1532-4303 ; 0277-0903
    ISSN (online) 1532-4303
    ISSN 0277-0903
    DOI 10.1080/02770903.2018.1543434
    Database MEDical Literature Analysis and Retrieval System OnLINE

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