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  1. Article ; Online: Letter from Australia.

    McDonald, Christine F

    Respirology (Carlton, Vic.)

    2024  Volume 29, Issue 2, Page(s) 187–188

    MeSH term(s) Humans ; Asthma ; Air Pollution ; Australia
    Language English
    Publishing date 2024-01-04
    Publishing country Australia
    Document type Letter
    ZDB-ID 1435849-9
    ISSN 1440-1843 ; 1323-7799
    ISSN (online) 1440-1843
    ISSN 1323-7799
    DOI 10.1111/resp.14655
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4957: Show issues Location:
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  2. Article: Home oxygen therapy.

    McDonald, Christine F

    Australian prescriber

    2022  Volume 45, Issue 1, Page(s) 21–24

    Abstract: Long-term home oxygen therapy improves survival in patients with chronic obstructive pulmonary disease and persistent, severe hypoxaemia. It is uncertain that this benefit extends to patients with other chronic lung diseases. Oxygen is a treatment for ... ...

    Abstract Long-term home oxygen therapy improves survival in patients with chronic obstructive pulmonary disease and persistent, severe hypoxaemia. It is uncertain that this benefit extends to patients with other chronic lung diseases. Oxygen is a treatment for hypoxaemia, not breathlessness. To confirm hypoxaemia, blood gas analysis is recommended before prescribing oxygen. There is limited and conflicting evidence that portable oxygen for exertional use is of benefit to patients with chronic obstructive pulmonary disease who do not have severe hypoxaemia. Laboratory studies show improvements in exercise capacity and dyspnoea, but these do not translate into significant benefits in the home setting. Patients should be educated regarding the expected benefits, risks and burdens of home oxygen therapy. It is particularly important that the patient does not smoke.
    Language English
    Publishing date 2022-02-01
    Publishing country Australia
    Document type Journal Article ; Review
    ZDB-ID 1075442-8
    ISSN 0312-8008
    ISSN 0312-8008
    DOI 10.18773/austprescr.2022.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3233: Show issues Location:
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  3. Article ; Online: Vaping and the lung: New evidence from the silent zone?

    McDonald, Christine F

    Respirology (Carlton, Vic.)

    2021  Volume 26, Issue 10, Page(s) 906–907

    MeSH term(s) Electronic Nicotine Delivery Systems ; Humans ; Lung ; Vaping/adverse effects
    Language English
    Publishing date 2021-08-18
    Publishing country Australia
    Document type Editorial ; Comment
    ZDB-ID 1435849-9
    ISSN 1440-1843 ; 1323-7799
    ISSN (online) 1440-1843
    ISSN 1323-7799
    DOI 10.1111/resp.14132
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    Zs.A 4957: Show issues Location:
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  4. Article ; Online: Standardized neonatal continuous infusion concentrations: A quality improvement initiative.

    Mulvihill, Christine / McDonald, Danielle

    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists

    2022  

    Abstract: Disclaimer: In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and ...

    Abstract Disclaimer: In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time.
    Purpose: Medication errors are a significant and preventable source of patient harm, especially in the neonatal population. Standardized infusion concentrations increase patient safety and streamline the workflow for pharmacists, nurses, and physicians.
    Methods: Neonatal continuous infusion concentrations were standardized and implemented into the electronic health record using an automated order panel. Pre- and postimplementation data were collected to assess the impact of this quality improvement initiative. The primary endpoint was the proportion of neonatal intensive care unit infusion orders that were compatible with "bolus from infusion" functionality in the syringe pump.
    Results: Before implementation, only 40% of eligible infusions were compatible with the "bolus from infusion" function, compared to 93% after implementation (P < 0.00001). Within the syringe pump, the ratio of total options to the number of concentrations per medication was reduced by 31%.
    Conclusion: Implementation of an order panel with defaulted standard infusion concentration selection improved workflow and optimized technology in the neonatal intensive care unit.
    Language English
    Publishing date 2022-10-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 1224627-x
    ISSN 1535-2900 ; 1079-2082
    ISSN (online) 1535-2900
    ISSN 1079-2082
    DOI 10.1093/ajhp/zxac299
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 419: Show issues Location:
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  5. Article ; Online: E-cigarettes for smoking cessation: Current state of play.

    McDonald, Christine F

    Respirology (Carlton, Vic.)

    2019  Volume 24, Issue 8, Page(s) 722–723

    Language English
    Publishing date 2019-06-24
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 1435849-9
    ISSN 1440-1843 ; 1323-7799
    ISSN (online) 1440-1843
    ISSN 1323-7799
    DOI 10.1111/resp.13630
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  6. Article ; Online: Ambulatory oxygen delivery-an answer: But what is the question?

    McDonald, Christine F

    Respirology (Carlton, Vic.)

    2019  Volume 24, Issue 4, Page(s) 294–295

    MeSH term(s) Exercise Tolerance ; Humans ; Oxygen ; Pulmonary Disease, Chronic Obstructive ; Respiratory Physiological Phenomena
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2019-02-12
    Publishing country Australia
    Document type Editorial ; Comment
    ZDB-ID 1435849-9
    ISSN 1440-1843 ; 1323-7799
    ISSN (online) 1440-1843
    ISSN 1323-7799
    DOI 10.1111/resp.13505
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  7. Article ; Online: Experiences of New Zealand registered nurses of Chinese ethnicity during the COVID-19 pandemic.

    Song, Jenny / McDonald, Christine

    Journal of clinical nursing

    2021  Volume 30, Issue 5-6, Page(s) 757–764

    Abstract: Aims: This study aimed to investigate the experiences and challenges of New Zealand registered nurses of Chinese ethnicity who have been working during the COVID-19 pandemic.: Background: New Zealand's nursing workforce is becoming increasingly ... ...

    Abstract Aims: This study aimed to investigate the experiences and challenges of New Zealand registered nurses of Chinese ethnicity who have been working during the COVID-19 pandemic.
    Background: New Zealand's nursing workforce is becoming increasingly multicultural as foreign nurses make up an essential part of the New Zealand health workforce. The ongoing COVID-19 pandemic has highlighted the contributions that nurses have made in providing front-line services to the public. However, little has been documented about challenges and experiences of this minority ethnic group-Chinese nurses-who have been working as registered nurses in New Zealand during the COVID-19 pandemic.
    Methods: This study used an anonymous online questionnaire and a thematic approach to establishing understandings of the experiences of New Zealand registered nurses of Chinese ethnicity in working through the COVID-19 pandemic. A total of 51 Chinese nurses completed this survey. A self-explanatory checklist for reporting results of Internet e-surveys (CHERRIES) was used for the purpose of the quality of this online survey.
    Results: The result showed that 47.06% participants (n = 24) reported negative experiences including racial discrimination, workplace bullying and judgement, while 52.94% (n = 27) participants reported positive working experiences including supports received in the workplace and positive recognition by the pubic in New Zealand.
    Conclusion: Ethnic minority nurses are key assets to the New Zealand health system. It is important to understand their experiences and challenges, particularly during the COVID-19 pandemic to make sure they are supported and protected from any physical and emotional injury.
    Relevance to clinical practice: COVID-19 has brought additional challenges and concerns to nurses who are working on the front line of health services. Having knowledge of nurses' working experiences will help with their job satisfaction and has potential implications for the sustainability of the New Zealand nursing workforce and retention strategies to address nursing workforce shortages which is foreseeable in New Zealand.
    MeSH term(s) Asian Continental Ancestry Group/psychology ; Asian Continental Ancestry Group/statistics & numerical data ; COVID-19/nursing ; China/ethnology ; Humans ; Minority Groups/psychology ; Minority Groups/statistics & numerical data ; New Zealand/epidemiology ; Nurses/psychology ; Nurses/statistics & numerical data
    Language English
    Publishing date 2021-01-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 1159483-4
    ISSN 1365-2702 ; 0962-1067 ; 1752-9816
    ISSN (online) 1365-2702
    ISSN 0962-1067 ; 1752-9816
    DOI 10.1111/jocn.15607
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    Zs.A 3764: Show issues Location:
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  8. Article ; Online: Eosinophils in chronic obstructive pulmonary disease: are they just another biomarker?

    McDonald, Christine F

    Current opinion in pulmonary medicine

    2019  Volume 26, Issue 2, Page(s) 169–174

    Abstract: Purpose of review: Interest in blood eosinophils as a biomarker of responsiveness to therapy in chronic obstructive pulmonary disease (COPD) continues to grow, with recommendations regarding their adjunctive use incorporated into the GOLD 2019 treatment ...

    Abstract Purpose of review: Interest in blood eosinophils as a biomarker of responsiveness to therapy in chronic obstructive pulmonary disease (COPD) continues to grow, with recommendations regarding their adjunctive use incorporated into the GOLD 2019 treatment algorithm. The present review summarizes some key recent papers referencing differential treatment effects based on blood eosinophil counts.
    Recent findings: Post-hoc analyses of trials of inhaled corticosteroids in COPD have shown greater treatment responses in patients with higher blood eosinophil levels, with some exceptions. Eosinophil-directed treatment with oral corticosteroids showed equivalent benefits to noneosinophil-directed therapy, with reduced corticosteroid exposure. Prespecified analyses of recent prospective trials of therapies incorporating inhaled corticosteroids were generally supportive of previous findings, so evidence for the use of blood eosinophils as biomarkers is gathering. Nonetheless, the anti-interleukin (IL)-5 receptor antagonist benralizumab, which depletes blood eosinophils, showed no treatment benefit in patients with COPD selected for eosinophilic phenotype and treatment of COPD with the IL-5 antagonist, mepolizumab showed inconsistent results.
    Summary: The 2019 GOLD COPD Strategy document embraced the use of the blood eosinophil to guide ICS therapy in management of patients with stable COPD and frequent exacerbations. Although post-hoc and several prospective studies with prespecified subgroup analyses have supported this approach, questions still remain about how to incorporate this new assessment tool into real-life management of COPD and more research is required to validate its adoption into clinical practice. There is an absence of data to support the use of biologic therapy in patients with an eosinophilic COPD phenotype at this stage.
    MeSH term(s) Biomarkers, Pharmacological/blood ; Eosinophils ; Humans ; Leukocyte Count/methods ; Pulmonary Disease, Chronic Obstructive/blood ; Pulmonary Disease, Chronic Obstructive/therapy ; Respiratory System Agents/pharmacology ; Treatment Outcome
    Chemical Substances Biomarkers, Pharmacological ; Respiratory System Agents
    Language English
    Publishing date 2019-12-02
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1285505-4
    ISSN 1531-6971 ; 1070-5287 ; 1078-1641
    ISSN (online) 1531-6971
    ISSN 1070-5287 ; 1078-1641
    DOI 10.1097/MCP.0000000000000660
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    Zs.A 4900: Show issues Location:
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  9. Article ; Online: Exercise desaturation and oxygen therapy in ILD and COPD: Similarities, differences and therapeutic relevance.

    McDonald, Christine F

    Respirology (Carlton, Vic.)

    2018  Volume 23, Issue 4, Page(s) 350–351

    MeSH term(s) Exercise ; Exercise Test ; Humans ; Oxygen ; Oxygen Inhalation Therapy ; Pulmonary Disease, Chronic Obstructive
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2018
    Publishing country Australia
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1435849-9
    ISSN 1440-1843 ; 1323-7799
    ISSN (online) 1440-1843
    ISSN 1323-7799
    DOI 10.1111/resp.13242
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  10. Article ; Online: Eosinophil Biology in COPD.

    McDonald, Christine F

    The New England journal of medicine

    2017  Volume 377, Issue 17, Page(s) 1680–1682

    MeSH term(s) Eosinophils ; Humans ; Leukocyte Count ; Pulmonary Disease, Chronic Obstructive
    Language English
    Publishing date 2017--26
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMe1710326
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