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  1. Book ; Thesis: Chronisch obstruktive Lungenerkrankung bei HIV-Infizierten

    Breitenmoser, Carina / Behrens, Georg Martin Norbert

    Prävalenz, Risikofaktoren und Screening

    2021  

    Institution Medizinische Hochschule Hannover
    Klinik für Immunologie und Rheumatologie
    Author's details vorgelegt von Carina Breitenmoser ; aus der Klinik für Rheumatologie und Immunologie der Medizinischen Hochschule Hannover ; Betreuer der Arbeit: Prof. Dr. med. Georg Behrens
    Language German
    Size 100 Blätter, Diagramme, 30 cm
    Publishing place Hannover
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Medizinische Hochschule Hannover, 2021
    HBZ-ID HT021157009
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2021 E 1481 order for loan Magazin

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  2. Book ; Conference proceedings ; Thesis: Aktuelle Seroprävalenz, Impfstatus und prädiktiver Wert der Leberenzyme für Hepatitis B bei Flüchtlingen in Deutschland

    Hampel, Annika / Behrens, Georg Martin Norbert

    2019  

    Institution Medizinische Hochschule Hannover
    Event/congress Klinik für Immunologie und Rheumatologie
    Author's details vorgelegt von Annika Hampel, geb. Homann ; aus der Klinik für Immunologie und Rheumatologie der Medizinischen Hochschule Hannover (Direktor Herr Prof. Dr. med. R. E. Schmidt) ; Betreuer: Prof. Dr. med. Georg Behrens
    Language German
    Size 36 Blätter, Diagramme, 30 cm
    Publishing place Hannover
    Publishing country Germany
    Document type Book ; Conference proceedings ; Thesis
    Thesis / German Habilitation thesis Dissertation, Medizinische Hochschule Hannover, 2021
    Note Enthält 1 Zeitschriftenaufsatz aus "Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz", Jg. 59 (2016)
    HBZ-ID HT021024947
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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  3. Article: Beyond Viral Suppression.

    Behrens, Georg M N

    Open forum infectious diseases

    2021  Volume 8, Issue 10, Page(s) ofab044

    Language English
    Publishing date 2021-01-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofab044
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Close to Zero, but Not Zero: What Is an Acceptable HIV Transmission Risk Through Breastfeeding?

    Behrens, Georg M N / Aebi-Popp, Karoline / Babiker, Abdel

    Journal of acquired immune deficiency syndromes (1999)

    2021  Volume 89, Issue 4, Page(s) e42

    MeSH term(s) Breast Feeding ; Female ; HIV Infections/prevention & control ; HIV Infections/transmission ; Humans ; Infectious Disease Transmission, Vertical/prevention & control ; Risk Factors
    Language English
    Publishing date 2021-12-05
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 645053-2
    ISSN 1944-7884 ; 1077-9450 ; 0897-5965 ; 0894-9255 ; 1525-4135
    ISSN (online) 1944-7884 ; 1077-9450
    ISSN 0897-5965 ; 0894-9255 ; 1525-4135
    DOI 10.1097/QAI.0000000000002887
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2442: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Hypophosphatemia in people with HIV: no benefit when switching from tenofovir disoproxil fumarate to tenfovir alafenamide.

    Sandmann, Lisa / Stoll, Matthias / Behrens, Georg M N

    AIDS (London, England)

    2021  Volume 35, Issue 9, Page(s) 1516–1518

    Abstract: Treatment with tenofovir disoproxil fumarate (TDF) has been associated with hypophosphatemia mainly because of injury of the renal proximal tubulus. Studies on the impact of tenfovir alafenamide (TAF) on phosphate homeostasis in people with HIV (PWH) are ...

    Abstract Treatment with tenofovir disoproxil fumarate (TDF) has been associated with hypophosphatemia mainly because of injury of the renal proximal tubulus. Studies on the impact of tenfovir alafenamide (TAF) on phosphate homeostasis in people with HIV (PWH) are limited. Prompted by a patient with phosphate wasting under tenofovir but no other evidence for tubular dysfunction, a retrospective cohort analysis with 102 PWH revealed that hypophosphatemia remained largely unchanged after switching from TDF to TAF.
    MeSH term(s) Anti-HIV Agents/adverse effects ; Fumarates/therapeutic use ; HIV Infections/complications ; HIV Infections/drug therapy ; Humans ; Hypophosphatemia/chemically induced ; Hypophosphatemia/drug therapy ; Retrospective Studies ; Tenofovir/adverse effects
    Chemical Substances Anti-HIV Agents ; Fumarates ; Tenofovir (99YXE507IL)
    Language English
    Publishing date 2021-04-03
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639076-6
    ISSN 1473-5571 ; 0269-9370 ; 1350-2840
    ISSN (online) 1473-5571
    ISSN 0269-9370 ; 1350-2840
    DOI 10.1097/QAD.0000000000002905
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2228: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Immune responses following BNT162b2 XBB.1.5 vaccination in patients on haemodialysis in Germany.

    Cossmann, Anne / Hoffmann, Markus / Stankov, Metodi V / Lürken, Karsten / Morillas Ramos, Gema / Kempf, Amy / Nehlmeier, Inga / Pöhlmann, Stefan / Behrens, Georg M N / Dopfer-Jablonka, Alexandra

    The Lancet. Infectious diseases

    2024  Volume 24, Issue 3, Page(s) e145–e146

    MeSH term(s) Humans ; BNT162 Vaccine ; Germany/epidemiology ; Renal Dialysis ; Immunity ; Vaccination ; Antibodies, Viral
    Chemical Substances BNT162 Vaccine ; Antibodies, Viral
    Language English
    Publishing date 2024-01-08
    Publishing country United States
    Document type Letter
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(23)00783-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5743: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Autolysosomal activation combined with lysosomal destabilization efficiently targets myeloid leukemia cells for cell death.

    Shah, Harshit / Stankov, Metodi / Panayotova-Dimitrova, Diana / Yazdi, Amir / Budida, Ramachandramouli / Klusmann, Jan-Henning / Behrens, Georg M N

    Frontiers in oncology

    2023  Volume 13, Page(s) 999738

    Abstract: Introduction: Current cancer research has led to a renewed interest in exploring lysosomal membrane permeabilization and lysosomal cell death as a targeted therapeutic approach for cancer treatment. Evidence suggests that differences in lysosomal ... ...

    Abstract Introduction: Current cancer research has led to a renewed interest in exploring lysosomal membrane permeabilization and lysosomal cell death as a targeted therapeutic approach for cancer treatment. Evidence suggests that differences in lysosomal biogenesis between cancer and normal cells might open a therapeutic window. Lysosomal membrane stability may be affected by the so-called '
    Methods: We used a panel of multiple myeloid leukemia (ML) cell lines as well as leukemic patient samples and updated methodology to study auto-lysosomal compartment, lysosomal membrane permeabilization and lysosomal cell death.
    Results: Our analyses demonstrated several-fold higher constitutive autolysosomal activity in ML cells as compared to human CD34
    Discussion: In conclusion, mefloquine treatment combined with mTOR inhibition synergistically induced targeted ML cell death without additional toxicity. Taken together, these data provide a molecular mechanism and thus a rationale for a therapeutic approach for specific targeting of ML lysosomes.
    Language English
    Publishing date 2023-02-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.999738
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Healthcare Workers' Perceptions and Medically Approved COVID-19 Infection Risk: Understanding the Mental Health Dimension of the Pandemic. A German Hospital Case Study.

    Kuhlmann, Ellen / Behrens, Georg M N / Cossmann, Anne / Homann, Stefanie / Happle, Christine / Dopfer-Jablonka, Alexandra

    Frontiers in public health

    2022  Volume 10, Page(s) 898840

    Abstract: Introduction: This study analyses how healthcare workers (HCWs) perceived risks, protection and preventive measures during the COVID-19 pandemic in relation to medically approved risks and organizational measures. The aim is to explore "blind spots" of ... ...

    Abstract Introduction: This study analyses how healthcare workers (HCWs) perceived risks, protection and preventive measures during the COVID-19 pandemic in relation to medically approved risks and organizational measures. The aim is to explore "blind spots" of pandemic protection and make mental health needs of HCWs visible.
    Methods: We have chosen an "optimal-case" scenario of a high-income country with a well-resourced hospital sector and low HCW infection rate at the organizational level to explore governance gaps in HCW protection. A German multi-method hospital study at Hannover Medical School served as empirical case; document analysis, expert information and survey data (
    Results: The results reveal a low risk of 1% medically approved infections among participants, but a much higher mean personal risk estimate of 15%. The majority (68.4%) expressed "some" to "very strong" fear of acquiring infection at the workplace. Individual protective behavior and compliance with protective workplace measures were estimated as very high. Yet only about half of the respondents felt strongly protected by the employer; 12% even perceived "no" or "little" protection. Gender and contact with COVID-19 patients had no significant effect on the estimations of infection risks and protective workplace behavior, but nursing was correlated with higher levels of personal risk estimations and fear of infection.
    Conclusions: A strong mismatch between low medically approved risk and personal risk perceptions of HCWs brings stressors and threats into view, that may be preventable through better information, training/education and risk communication and through investment in mental health and inclusion in pandemic preparedness plans.
    MeSH term(s) COVID-19/epidemiology ; Health Personnel/psychology ; Hospitals ; Humans ; Mental Health ; Pandemics/prevention & control ; SARS-CoV-2
    Language English
    Publishing date 2022-05-20
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2022.898840
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Effect of hybrid immunity and bivalent booster vaccination on omicron sublineage neutralisation.

    Hoffmann, Markus / Behrens, Georg M N / Arora, Prerna / Kempf, Amy / Nehlmeier, Inga / Cossmann, Anne / Manthey, Luis / Dopfer-Jablonka, Alexandra / Pöhlmann, Stefan

    The Lancet. Infectious diseases

    2022  Volume 23, Issue 1, Page(s) 25–28

    MeSH term(s) Humans ; Adaptive Immunity ; Vaccination ; Antibodies, Viral
    Chemical Substances Antibodies, Viral
    Language English
    Publishing date 2022-12-05
    Publishing country United States
    Document type Letter
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(22)00792-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5743: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  10. Article ; Online: Host cell entry and neutralisation sensitivity of the SARS-CoV-2 XBB.1.16 lineage.

    Nehlmeier, Inga / Kempf, Amy / Arora, Prerna / Cossmann, Anne / Dopfer-Jablonka, Alexandra / Stankov, Metodi V / Schulz, Sebastian R / Jäck, Hans-Martin / Behrens, Georg M N / Pöhlmann, Stefan / Hoffmann, Markus

    Cellular & molecular immunology

    2023  Volume 20, Issue 8, Page(s) 969–971

    MeSH term(s) Humans ; COVID-19 ; SARS-CoV-2 ; Virus Internalization
    Language English
    Publishing date 2023-05-08
    Publishing country China
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 2435097-7
    ISSN 2042-0226 ; 1672-7681
    ISSN (online) 2042-0226
    ISSN 1672-7681
    DOI 10.1038/s41423-023-01030-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    Zs.A 6681: Show issues Location:
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