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Article ; Online: Probing the thermoelectric properties of aluminium-doped copper iodide.

Venkata Ramana, Tatavarthi Veera / Battabyal, Manjusha / Kumar, Santosh / Satapathy, Dillip K / Kumar, Ravi

Physical chemistry chemical physics : PCCP

2024 Volume 26, Issue 17, Page(s) 13287–13299

Abstract: ... been optimized to maximize TE performance. At 400 K, the highest TE power factor and figure of merit ...

Abstract	Copper iodide, an environmentally friendly material abundant in nature, holds great significance for room temperature thermoelectric (TE) applications owing to its high Seebeck coefficient and optical transparency. However, to fully unlock its thermoelectric potential and match the performance of conventional TE materials, there is a need to further enhance its electrical conductivity. In this study, we have successfully synthesized nano-crystalline powders of both undoped and aluminium-doped CuI at room temperature using the chemical precipitation method in an ethanol medium. The concentration of aluminium dopant has been optimized to maximize TE performance. At 400 K, the highest TE power factor and figure of merit achieved are 79 μW m
Language	English
Publishing date	2024-05-01
Publishing country	England
Document type	Journal Article
ZDB-ID	1476244-4
ISSN	1463-9084 ; 1463-9076
ISSN (online)	1463-9084
ISSN	1463-9076
DOI	10.1039/d4cp00593g
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Article ; Online: Exploring the potential of neem and tamarind gum as release retardants: Design and statistical optimisation of vildagliptin extended release matrix systems using D-optimal quadratic mixture design.

Kumar, N Ravi / Rao, G S N Koteswara / Ratna, J Vijaya / Murthy, K V Ramana

International journal of biological macromolecules

2024 Volume 259, Issue Pt 1, Page(s) 129136

Abstract: Exploring the significant role of natural polymers in developing drug delivery systems has been a promising area of research interest. The current investigation uses a D-optimal quadratic mixture design to design and evaluate neem and tamarind gum-based ... ...

Abstract	Exploring the significant role of natural polymers in developing drug delivery systems has been a promising area of research interest. The current investigation uses a D-optimal quadratic mixture design to design and evaluate neem and tamarind gum-based vildagliptin extended-release matrix tablets. Studying the combination effect of gums is one of the major objectives. Initial screening studies were performed to select the factors and their levels. The variables selected at different levels in mg/tablet are neem gum, tamarind gum, polyvinylpyrrolidone, and lactose monohydrate. Based on the screening experiments with both gums, the polymer content of 165 mg was chosen as the highest level in the DOE. Nineteen runs were generated to screen the desired parameters as responses. The total weight of the formulation was kept constant at 275 mg. Time (hours) required for 50 %, 90 % and 100 % of drug release and tablet hardness were selected as the responses for each run. The wet granulation method was adopted, and the critical variables were optimised using the design of experiments following Design Expert software. Statistical analysis was conducted, and the optimised formulations were prepared and evaluated to compare with the predicted responses. Stability studies were performed for the optimised batches. Results indicated that the prepared batches met the compendial limits and confirmed the application of neem and tamarind gum in the development of extended-release tablets of vildagliptin for 24 h. An optimised formulation comprising of 16.52 mg of neem gum and 148.48 mg of tamarind gum with a hardness of 7.5-8.5 kp produced 50 %, 90 % and 100 % drug release in 12, 22 and 25 h.
MeSH term(s)	Delayed-Action Preparations ; Tamarindus ; Vildagliptin ; Plant Gums ; Tablets
Chemical Substances	Delayed-Action Preparations ; Vildagliptin (I6B4B2U96P) ; Plant Gums ; Tablets
Language	English
Publishing date	2024-01-03
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2023.129136
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Article ; Online: Comparative evaluation of sorghum and pearl millet forage silages with maize

Vinutha, K.S. / Khan, A.A. / Ravi, D. / Prasad, Kodukula V.S.V. / Ramana Reddy, Y. / Jones, Christopher S. / Blümmel, Michael

Animal Nutrition and Feed Technology

2021

Keywords	digestibility ; forage ; pearl millet ; silage ; sorghum ; maize ; crops
Language	English
Publishing date	2021-09-22T15:01:30Z
Publisher	Diva Enterprises Private Limited
Publishing country	fr
Document type	Article ; Online
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Article ; Online: 30-Day Clinical Outcomes of a Self-Expanding Transcatheter Aortic Valve: The International PORTICO NG Study.

Reardon, Michael J / Chehab, Bassem / Smith, Dave / Walton, Antony S / Worthley, Stephen G / Manoharan, Ganesh / Sultan, Ibrahim / Yong, Gerald / Harrington, Katherine / Mahoney, Paul / Kleiman, Neal / Makkar, Raj R / Fontana, Gregory / DeLago, Augustin / Ramana, Ravi K / Bates, Nicholas / Søndergaard, Lars

JACC. Cardiovascular interventions

2023 Volume 16, Issue 6, Page(s) 681–689

Abstract: Background: The self-expanding, intra-annular Navitor (Abbott Structural Heart) valve includes an outer cuff to reduce paravalvular leak (PVL) and large stent cells for future coronary access.: Objectives: The purpose of the PORTICO NG (Evaluation of ...

Abstract	Background: The self-expanding, intra-annular Navitor (Abbott Structural Heart) valve includes an outer cuff to reduce paravalvular leak (PVL) and large stent cells for future coronary access. Objectives: The purpose of the PORTICO NG (Evaluation of the Portico NG [Next Generation] Transcatheter Aortic Valve in High and Extreme Risk Patients With Symptomatic Severe Aortic Stenosis) study is to evaluate the safety and effectiveness of the Navitor valve in patients with symptomatic, severe aortic stenosis who are at high or extreme surgical risk. Methods: PORTICO NG is a prospective, multicenter, global study with follow-up at 30 days, 1 year, and annually through 5 years. The primary endpoints are all-cause mortality and moderate or greater PVL at 30 days. Valve Academic Research Consortium-2 events and valve performance are assessed by an independent clinical events committee and echocardiographic core laboratory. Results: A total of 260 subjects were treated at 26 clinical sites across Europe, Australia, and the United States between September 2019 and August 2022. The mean age was 83.4 ± 5.4 years, 57.3% were female, and the average Society of Thoracic Surgeons score was 3.9% ± 2.1%. At 30 days, the rate of all-cause mortality was 1.9%, and no subjects had moderate or greater PVL. The rate of disabling stroke was 1.9%, life-threatening bleeding was 3.8%, stage 3 acute kidney injury was 0.8%, major vascular complications were 4.2%, and new permanent pacemaker implantation was 19.0%. Hemodynamic performance included a mean gradient of 7.4 ± 3.5 mm Hg and an effective orifice area of 2.00 ± 0.47 cm Conclusions: The Navitor valve is safe and effective for the treatment of subjects with severe aortic stenosis who are at high or greater risk for surgery, which is supported by low rates of adverse events and PVL. (Evaluation of the Portico NG [Next Generation] Transcatheter Aortic Valve in High and Extreme Risk Patients With Symptomatic Severe Aortic Stenosis [PORTICO NG]; NCT04011722).
MeSH term(s)	Humans ; Female ; United States ; Aged ; Aged, 80 and over ; Male ; Aortic Valve/diagnostic imaging ; Aortic Valve/surgery ; Aortic Valve Stenosis/diagnostic imaging ; Aortic Valve Stenosis/surgery ; Aortic Valve Stenosis/complications ; Transcatheter Aortic Valve Replacement/adverse effects ; Prospective Studies ; Treatment Outcome ; Postoperative Complications/etiology ; Heart Valve Prosthesis/adverse effects ; Prosthesis Design
Language	English
Publishing date	2023-02-27
Publishing country	United States
Document type	Multicenter Study ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2452157-7
ISSN	1876-7605 ; 1936-8798
ISSN (online)	1876-7605
ISSN	1936-8798
DOI	10.1016/j.jcin.2023.02.002
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Article ; Online: Farming systems in sheep rearing: Impact on growth and reproductive performance, nutrient digestibility, disease incidence and heat stress indices.

Karthik, D / Suresh, J / Reddy, Y Ravindra / Sharma, G R K / Ramana, J V / Gangaraju, G / Pradeep Kumar Reddy, Y / Yasaswini, D / Adegbeye, M J / Reddy, P Ravi Kanth

PloS one

2021 Volume 16, Issue 1, Page(s) e0244922

Abstract: The experiment was conducted with an intent to know the effect of different farming systems on the growth performance, nutrient digestibility coefficients, reproductive traits, disease incidence, heat stress indices, and cost economics of Nellore sheep. ... ...

Abstract	The experiment was conducted with an intent to know the effect of different farming systems on the growth performance, nutrient digestibility coefficients, reproductive traits, disease incidence, heat stress indices, and cost economics of Nellore sheep. The study includes two parallel trials to prevent the influence of age on heat stress indices (panting score and erythrocyte osmotic fragility (EOF)). One hundred and twenty lambs (60 ram-lambs and 60 ewe-lambs) were allotted in a randomized block design under extensive, semi-intensive, and intensive systems for trial I, whereas trial II include eighteen rams assigned to the three respective farming systems in a completely randomised design. Both, season (summer) and grazing practice increased the panting score and EOF. The heat stress indices were positively correlated (P<0.01) with dry-bulb temperature and temperature-humidity index (THI) and inversely correlated (P<0.01) to relative humidity. Allotting the sheep to intensive system increased (P<0.001) weight gain and average daily gain with higher effect in males compared to females. The parameters of asymptotic weight (A), integration constant (B), and maturation rate were higher for intensive males. The male Nellore lambs had higher asymptotic weight and lower maturity rate than females, irrespective of the rearing system. Intensive sheep revealed a higher dry matter intake, digestibility coefficients, feed conversion ratio. The instantaneous bite mass (IBM) was higher for Commelina benghalensis, while instantaneous bite frequency (IBF), instantaneous intake rate (IIR) were higher for Cyanodon dactylon and amaranthus viridis, respectively. The proportion of intakes were highest for Stylo hemata followed by Cynodon dactylon and Tridax procumbens species. No differences were observed for the weight at puberty, oestrus cycle length, oestrus duration, conception percent, gestation period, and lambing percent in three rearing systems; however, the age at puberty was lower (P<0.001) and the birth weight was higher (P<0.001) for sheep reared under intensive farming system. Highest disease incidence was observed in rainy and winter seasons, particularly in sheep reared under extensive system. The capital expenditure was same for the three rearing systems, while the recurring expenditure was higher for Intensive farming system. The gross income and net income were higher for intensive system on account of higher weight gains. However, the higher returns per rupee of expenditure project the extensive farming as an ideal rearing system for small farmers and entrepreneurs with a low initial capital.
MeSH term(s)	Agriculture/methods ; Animals ; Digestion ; Feeding Behavior ; Heat-Shock Response ; Incidence ; Nutrients/metabolism ; Reproduction ; Sheep/physiology ; Sheep Diseases/epidemiology
Language	English
Publishing date	2021-01-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0244922
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Article: Adaptive profiles of Nellore sheep with reference to farming system and season: physiological, hemato-biochemical, hormonal, oxidative-enzymatic and reproductive standpoint.

Karthik, D / Suresh, J / Reddy, Y Ravindra / Sharma, G R K / Ramana, J V / Gangaraju, G / Reddy, P Pandu Ranga / Reddy, Y Pradeep Kumar / Yasaswini, D / Adegbeye, M J / Reddy, P Ravi Kanth

Heliyon

2021 Volume 7, Issue 5, Page(s) e07117

Abstract: This paper outlines the effect of farming systems with reference to season on the body condition score (BCS) and adaptive profile (physiological, hemato-biochemical, hormonal, enzymatic and reproductive parameters) of Nellore sheep. In trial 1, sixty ewe- ...

Abstract	This paper outlines the effect of farming systems with reference to season on the body condition score (BCS) and adaptive profile (physiological, hemato-biochemical, hormonal, enzymatic and reproductive parameters) of Nellore sheep. In trial 1, sixty ewe-lambs were allotted to extensive, semi-intensive, and intensive rearing systems (n = 20) and evaluated for BCS at puberty, mating, 2 weeks pre-lambing and 2, 4, 8, and 12 weeks post-lambing. In trial 2, eighteen rams were distributed evenly to three farming systems (n = 6) and evaluated for physiological, hemato-biochemical, hormonal, enzymatic, and reproductive parameters concerning three seasons. Although the scores did not differ among the groups, the Kruskal-Wallis ranks of BCS revealed a higher energy status of intensive ewes at different physiological conditions. The sheep reared under extensive and semi-intensive systems displayed higher temperature, pulse rate and respiratory rate with predominant effects in summer season. Similarly, both systems exhibited higher WBC and lower haemoglobin, PCV, and RBC contents without affecting MVC, MCH, MCHC, and differential leucocyte count. The percent haemoglobin and RBC count were higher in winter compared to summer months, whereas WBC count followed an exactly opposite pattern. The sheep reared in intensive system showed higher glucose, total protein, albumin, cholesterol, T3, T4, calcium, and phosphorus; however, the globulin, creatinine, uric acid, aspartate amino transferase (AST), alanine amino transferase (ALT), superoxide dismutase (SOD), malondialdehyde (MDA), glutathione peroxidase, and catalase levels were elevated in extensive and semi-intensive systems. The dartos muscle extension (DME) and scrotum sweating rate (SSR) were higher for the sheep reared under extensive system, especially during summer season; while the seminal parameters viz., total sperm count, progressive sperm motility, and plasma membrane integrity were lower for extensive and semi-intensive sheep. No interactions were noticed for any of the parameters, except for cortisol, DME, and SSR, which showed significant interactions for rearing system vs. season. Our results showed dynamic adaptive mechanisms of the Nellore sheep in relation to different stressors like grazing for long distances, inadequate nutrition, and heat stress, revealing the heat resilient ability in harsh environmental conditions. Further, the analyzed vector plot showed that the AST, GPx, Cortisol, SOD, Catalase, WBC, PR, T4, total abnormalities, and major abnormalities were the major contributors for adapting during combined stressors.
Language	English
Publishing date	2021-05-26
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2021.e07117
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Article ; Online: Farming systems in sheep rearing

D Karthik / J Suresh / Y Ravindra Reddy / G R K Sharma / J V Ramana / G Gangaraju / Y Pradeep Kumar Reddy / D Yasaswini / M J Adegbeye / P Ravi Kanth Reddy

PLoS ONE, Vol 16, Iss 1, p e

Impact on growth and reproductive performance, nutrient digestibility, disease incidence and heat stress indices.

2021 Volume 0244922

Abstract	The experiment was conducted with an intent to know the effect of different farming systems on the growth performance, nutrient digestibility coefficients, reproductive traits, disease incidence, heat stress indices, and cost economics of Nellore sheep. The study includes two parallel trials to prevent the influence of age on heat stress indices (panting score and erythrocyte osmotic fragility (EOF)). One hundred and twenty lambs (60 ram-lambs and 60 ewe-lambs) were allotted in a randomized block design under extensive, semi-intensive, and intensive systems for trial I, whereas trial II include eighteen rams assigned to the three respective farming systems in a completely randomised design. Both, season (summer) and grazing practice increased the panting score and EOF. The heat stress indices were positively correlated (P<0.01) with dry-bulb temperature and temperature-humidity index (THI) and inversely correlated (P<0.01) to relative humidity. Allotting the sheep to intensive system increased (P<0.001) weight gain and average daily gain with higher effect in males compared to females. The parameters of asymptotic weight (A), integration constant (B), and maturation rate were higher for intensive males. The male Nellore lambs had higher asymptotic weight and lower maturity rate than females, irrespective of the rearing system. Intensive sheep revealed a higher dry matter intake, digestibility coefficients, feed conversion ratio. The instantaneous bite mass (IBM) was higher for Commelina benghalensis, while instantaneous bite frequency (IBF), instantaneous intake rate (IIR) were higher for Cyanodon dactylon and amaranthus viridis, respectively. The proportion of intakes were highest for Stylo hemata followed by Cynodon dactylon and Tridax procumbens species. No differences were observed for the weight at puberty, oestrus cycle length, oestrus duration, conception percent, gestation period, and lambing percent in three rearing systems; however, the age at puberty was lower (P<0.001) and the birth weight was higher (P<0.001) for sheep reared under intensive farming system. Highest disease incidence was observed in rainy and winter seasons, particularly in sheep reared under extensive system. The capital expenditure was same for the three rearing systems, while the recurring expenditure was higher for Intensive farming system. The gross income and net income were higher for intensive system on account of higher weight gains. However, the higher returns per rupee of expenditure project the extensive farming as an ideal rearing system for small farmers and entrepreneurs with a low initial capital.
Keywords	Medicine ; R ; Science ; Q
Subject code	630
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
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Article: Decrypting bio-molecular variability in small ruminants and antioxidants to combat bio-meteorological stress in semi-arid tropics

Pankaj, Prabhatkumar / Ramana, D. B. V. / Nirmala, G. / Shankar, K. Ravi / Rao, Ch. Srinivasa

Journal of agrometeorology

2017 Volume 19, Issue 2, Page(s) 99

Language	English
Document type	Article
ZDB-ID	2235052-4
ISSN	0972-1665
Database	Current Contents Nutrition, Environment, Agriculture

In stock of ZB MED Bonn / Germany

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Article: Percutaneous coronary intervention in patients with acute coronary syndrome: focus on bivalirudin.

Ramana, Ravi K / Lewis, Bruce E

Vascular health and risk management

2008 Volume 4, Issue 3, Page(s) 493–505

Abstract: Previously, indirect thrombin inhibitors such as unfractionated heparin or low-molecular-weight heparin were used as a standard anticoagulation during percutaneous coronary intervention to prevent procedural thrombotic complications but at a risk of ... ...

Abstract	Previously, indirect thrombin inhibitors such as unfractionated heparin or low-molecular-weight heparin were used as a standard anticoagulation during percutaneous coronary intervention to prevent procedural thrombotic complications but at a risk of hemorrhagic complications. More recently, bivalirudin, a member of the direct thrombin inhibitor class, has been shown to have 1) predictable pharmacokinetics, 2) ability to inhibit free- and clot-bound thrombin, 3) no properties of platelet activation, 4) avoidance of heparin-induced thrombocytopenia, and 5) a significant reduction of bleeding without a reduction in thrombotic or ischemic endpoints compared to heparin and glycoprotein IIbIIIa inhibitors when used in patients presenting with acute coronary syndrome who are planned for an invasive treatment strategy.
MeSH term(s)	Acute Coronary Syndrome/epidemiology ; Acute Coronary Syndrome/physiopathology ; Acute Coronary Syndrome/therapy ; Anemia/epidemiology ; Angina, Unstable/drug therapy ; Angina, Unstable/physiopathology ; Angioplasty, Balloon, Coronary ; Anticoagulants/adverse effects ; Anticoagulants/pharmacology ; Anticoagulants/therapeutic use ; Antithrombins/pharmacology ; Antithrombins/therapeutic use ; Blood Coagulation/physiology ; Comorbidity ; Coronary Thrombosis/prevention & control ; Heparin/adverse effects ; Hirudins/adverse effects ; Hirudins/pharmacology ; Humans ; Myocardial Infarction/prevention & control ; Peptide Fragments/adverse effects ; Peptide Fragments/pharmacology ; Peptide Fragments/therapeutic use ; Recombinant Proteins/adverse effects ; Recombinant Proteins/pharmacology ; Recombinant Proteins/therapeutic use ; Thrombocytopenia/chemically induced
Chemical Substances	Anticoagulants ; Antithrombins ; Hirudins ; Peptide Fragments ; Recombinant Proteins ; Heparin (9005-49-6) ; bivalirudin (TN9BEX005G)
Language	English
Publishing date	2008-09-19
Publishing country	New Zealand
Document type	Journal Article ; Review
ZDB-ID	2186568-1
ISSN	1178-2048 ; 1176-6344
ISSN (online)	1178-2048
ISSN	1176-6344
DOI	10.2147/vhrm.s2455
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Article ; Online: To Reduced the Energy Conception in Wireless Sensor Networks by Using Selective Message Forwarding Schemes

K. Venkata Ramana / M. Ravi Kishor

International Journal of Innovative Technology and Exploring Engineering, Vol 1, Iss 1, Pp 30-

2012 Volume 33

Abstract: In a wireless sensor network where nodes havelimited energy and forward messages of different priorities arefrequent in the context of wireless sensor networks. Sointroduced several selective message forwarding policies to saveenergy and extend the ... ...

Abstract	In a wireless sensor network where nodes havelimited energy and forward messages of different priorities arefrequent in the context of wireless sensor networks. Sointroduced several selective message forwarding policies to saveenergy and extend the lifetime of WSN. Forwarding schemeswere designed for three different scenarios:1) when sensorsmaximize the importance of their own transmitted messages 2)when sensors maximize the importance of messages that havebeen successfully retransmitted by at least one of its neighbors;and 3) when sensors maximize the importance of the messagesthat successfully arrive to the sink . The three schemes have beencompared under different criteria. From an overall networkefficiency perspective, the first scheme performed worse that itscounterparts, but it required less signaling overhead. Moresophisticated schemes will achieve better importanceperformance, but will also require information from othersensors. It is a greater impact on the overall networkperformance.
Keywords	AODOV ; Markov Decision ; Bayesian Decision Modal ; wireless sensor networks. ; Electronic computers. Computer science ; QA75.5-76.95 ; Instruments and machines ; QA71-90 ; Mathematics ; QA1-939 ; Science ; Q ; DOAJ:Computer Science ; DOAJ:Technology and Engineering
Subject code	003
Language	English
Publishing date	2012-06-01T00:00:00Z
Publisher	IJITEE
Document type	Article ; Online
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