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  1. Article ; Online: Targeted Proteomics Analysis of Staphylococcal Superantigenic Toxins in Menstrual Fluid from Women with Menstrual Toxic Shock Syndrome (mTSS).

    Courçon, Marie / Badiou, Cédric / Louwagie, Mathilde / Etievant, Sibyle / Jaquinod, Michel / Lina, Gérard / Brun, Virginie

    Toxins

    2022  Volume 14, Issue 12

    Abstract: Menstrual toxic shock syndrome (mTSS) is a rare life-threatening febrile illness that occurs in women using intravaginal menstrual protection. It is caused by toxic shock syndrome toxin 1 (TSST-1) produced ... ...

    Abstract Menstrual toxic shock syndrome (mTSS) is a rare life-threatening febrile illness that occurs in women using intravaginal menstrual protection. It is caused by toxic shock syndrome toxin 1 (TSST-1) produced by
    MeSH term(s) Humans ; Female ; Shock, Septic/microbiology ; Staphylococcus aureus/genetics ; Proteomics ; Enterotoxins ; Superantigens/genetics ; Exotoxins ; Multiple Organ Failure ; Staphylococcal Infections/microbiology
    Chemical Substances Enterotoxins ; Superantigens ; Exotoxins
    Language English
    Publishing date 2022-12-19
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2518395-3
    ISSN 2072-6651 ; 2072-6651
    ISSN (online) 2072-6651
    ISSN 2072-6651
    DOI 10.3390/toxins14120886
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Performance Assessment of SARS-CoV-2 PCR Assays Developed by WHO Referral Laboratories.

    Etievant, Sibyle / Bal, Antonin / Escuret, Vanessa / Brengel-Pesce, Karen / Bouscambert, Maude / Cheynet, Valérie / Generenaz, Laurence / Oriol, Guy / Destras, Gregory / Billaud, Geneviève / Josset, Laurence / Frobert, Emilie / Morfin, Florence / Gaymard, Alexandre

    Journal of clinical medicine

    2020  Volume 9, Issue 6

    Abstract: A reliable diagnostic assay is crucial to early detect new COVID-19 cases and limit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission. Since the onset of the COVID-19 pandemic, the World Health Organization has published several ... ...

    Abstract A reliable diagnostic assay is crucial to early detect new COVID-19 cases and limit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission. Since the onset of the COVID-19 pandemic, the World Health Organization has published several diagnostic molecular approaches developed by referral laboratories, including Charité (Germany), HKU (Hong Kong), China CDC (China), US CDC (United States), and Institut Pasteur, Paris (France). We aimed to compare the sensitivity and specificity of these different RT-PCR assays using SARS-CoV-2 cell culture supernatants and clinical respiratory samples. Overall, the different RT-PCR assays performed well for SARS-CoV-2 detection and were all specific except the N Charité (Germany), and N2 US CDC (United States) assays. RdRp Institut Pasteur (IP2, IP4), N China CDC, and N1 US CDC were found to be the most sensitive assays. The data presented herein are of prime importance to facilitate the equipment choice of diagnostic laboratories, as well as for the development of marketed tests.
    Keywords covid19
    Language English
    Publishing date 2020-06-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm9061871
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Performance Assessment of SARS-CoV-2 PCR Assays Developed by WHO Referral Laboratories

    Sibyle Etievant / Antonin Bal / Vanessa Escuret / Karen Brengel-Pesce / Maude Bouscambert / Valérie Cheynet / Laurence Generenaz / Guy Oriol / Gregory Destras / Geneviève Billaud / Laurence Josset / Emilie Frobert / Florence Morfin / Alexandre Gaymard

    Journal of Clinical Medicine, Vol 9, Iss 1871, p

    2020  Volume 1871

    Abstract: A reliable diagnostic assay is crucial to early detect new COVID-19 cases and limit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission. Since the onset of the COVID-19 pandemic, the World Health Organization has published several ... ...

    Abstract A reliable diagnostic assay is crucial to early detect new COVID-19 cases and limit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission. Since the onset of the COVID-19 pandemic, the World Health Organization has published several diagnostic molecular approaches developed by referral laboratories, including Charité (Germany), HKU (Hong Kong), China CDC (China), US CDC (United States), and Institut Pasteur, Paris (France). We aimed to compare the sensitivity and specificity of these different RT-PCR assays using SARS-CoV-2 cell culture supernatants and clinical respiratory samples. Overall, the different RT-PCR assays performed well for SARS-CoV-2 detection and were all specific except the N Charité (Germany), and N2 US CDC (United States) assays. RdRp Institut Pasteur (IP2, IP4), N China CDC, and N1 US CDC were found to be the most sensitive assays. The data presented herein are of prime importance to facilitate the equipment choice of diagnostic laboratories, as well as for the development of marketed tests.
    Keywords SARS-CoV-2 ; COVID-19 ; RT-PCR ; diagnostics ; sensitivity ; Medicine ; R ; covid19
    Subject code 610
    Language English
    Publishing date 2020-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Sensitivity assessment of SARS-CoV-2 PCR assays developed by WHO referral laboratories

    Etievant, Sibyle / Bal, Antonin / Escurret, Vanessa / Brengel-Pesce, Karen / Bouscambert, Maude / Cheynet, Valerie / Generenaz, Laurence / Oriol, Guy / Destras, Gregory / Billaud, Genevieve / Josset, Laurence / Frobert, Emilie / Morfin, Florence / Gaymard, Alexandre

    medRxiv

    Abstract: The sensitivity of SARS-CoV-2 RT-PCR tests developed by Charite (Germany), HKU (Hong-Kong), China CDC (China), US CDC (United-States), and Institut Pasteur, Paris (France) was assessed on SARS-CoV-2 cell culture supernatants and clinical samples. ... ...

    Abstract The sensitivity of SARS-CoV-2 RT-PCR tests developed by Charite (Germany), HKU (Hong-Kong), China CDC (China), US CDC (United-States), and Institut Pasteur, Paris (France) was assessed on SARS-CoV-2 cell culture supernatants and clinical samples. Although all RT-PCR assays performed well for SARS-CoV-2 detection, RdRp Institut Pasteur (IP2, IP4), N China CDC, and N1 US CDC were found to be the most sensitive.
    Keywords covid19
    Language English
    Publishing date 2020-05-04
    Publisher Cold Spring Harbor Laboratory Press
    Document type Article ; Online
    DOI 10.1101/2020.05.03.20072207
    Database COVID19

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  5. Article: Performance Assessment of SARS-CoV-2 PCR Assays Developed by WHO Referral Laboratories

    Etievant, Sibyle / Bal, Antonin / Escuret, Vanessa / Brengel-Pesce, Karen / Bouscambert, Maude / Cheynet, Valérie / Generenaz, Laurence / Oriol, Guy / Destras, Gregory / Billaud, Geneviève / Josset, Laurence / Frobert, Emilie / Morfin, Florence / Gaymard, Alexandre

    Abstract: A reliable diagnostic assay is crucial to early detect new COVID-19 cases and limit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission. Since the onset of the COVID-19 pandemic, the World Health Organization has published several ... ...

    Abstract A reliable diagnostic assay is crucial to early detect new COVID-19 cases and limit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission. Since the onset of the COVID-19 pandemic, the World Health Organization has published several diagnostic molecular approaches developed by referral laboratories, including Charité (Germany), HKU (Hong Kong), China CDC (China), US CDC (United States), and Institut Pasteur, Paris (France). We aimed to compare the sensitivity and specificity of these different RT-PCR assays using SARS-CoV-2 cell culture supernatants and clinical respiratory samples. Overall, the different RT-PCR assays performed well for SARS-CoV-2 detection and were all specific except the N Charité (Germany), and N2 US CDC (United States) assays. RdRp Institut Pasteur (IP2, IP4), N China CDC, and N1 US CDC were found to be the most sensitive assays. The data presented herein are of prime importance to facilitate the equipment choice of diagnostic laboratories, as well as for the development of marketed tests.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #599307
    Database COVID19

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