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  1. Article: Functional pH-Sensitive Film Containing Purple Sweet Potato Anthocyanins for Pork Freshness Monitoring and Cherry Preservation.

    Ke, Fahui / Liu, Duanwu / Qin, Juanjuan / Yang, Min

    Foods (Basel, Switzerland)

    2024  Volume 13, Issue 5

    Abstract: An antioxidative and pH-sensitive multifunctional film, incorporating anthocyanin-rich purple sweet potato extract (PPE) was fabricated from polyvinyl alcohol (PVA) and sodium alginate (SA)/sodium carboxymethyl cellulose (CMC-Na). The film was composed ... ...

    Abstract An antioxidative and pH-sensitive multifunctional film, incorporating anthocyanin-rich purple sweet potato extract (PPE) was fabricated from polyvinyl alcohol (PVA) and sodium alginate (SA)/sodium carboxymethyl cellulose (CMC-Na). The film was composed of 6:4 PVA:SA/CMC-Na (mass ratio, SA:CMC-Na at 1:1) with added PPE, and changed color with changes in pH, and also had useful UV-blocking, antioxidant, mechanical, and water vapor barrier properties, which enable its use as a food coating film. In addition, the incorporation of 300 mg PPE increased the biodegradability of the film in soil from 52.47 ± 1.12% to 64.29 ± 1.75% at 17 days. The pH sensitivity of the film enabled its successful use for the evaluation of pork freshness. Cherries coated with the film had an extended shelf life from 3-4 to 7-9 days, during storage at 25 °C. Consequently, the multifunctional film can be applied to packaging for real-time pH/freshness monitoring and for effectively preserving the freshness of meat and fruit.
    Language English
    Publishing date 2024-02-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods13050736
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Chiral Cp

    Wang, Juanjuan / Luo, Mu-Peng / Gu, Yi-Jie / Liu, Yu-Ying / Yin, Qin / Wang, Shou-Guo

    Angewandte Chemie (International ed. in English)

    2024  Volume 63, Issue 12, Page(s) e202400502

    Abstract: Chiral cyclopentadienyl-rhodium(III) ... ...

    Abstract Chiral cyclopentadienyl-rhodium(III) Cp
    Language English
    Publishing date 2024-02-13
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202400502
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Two Novel

    Qiao, Guanghang / Zhao, Juan / Liu, Juanjuan / Tan, Xiaoqian / Qin, Wentao

    Biology

    2022  Volume 11, Issue 10

    Abstract: ... ...

    Abstract The
    Language English
    Publishing date 2022-10-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2661517-4
    ISSN 2079-7737
    ISSN 2079-7737
    DOI 10.3390/biology11101459
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Ratio of hemoglobin to red cell distribution width: an inflammatory predictor of survival in AIDS-related DLBCL.

    Chen, Juanjuan / Wu, Yihua / Zhao, Han / Ruan, Guangjing / Qin, Shanfang

    Frontiers in immunology

    2024  Volume 15, Page(s) 1354325

    Abstract: Background: Despite the introduction of combined antiretroviral therapy, AIDS-related diffuse large B-cell lymphoma (AR-DLBCL) remains a prominent cancer among individuals living with HIV with a suboptimal prognosis. Identifying independent prognostic ... ...

    Abstract Background: Despite the introduction of combined antiretroviral therapy, AIDS-related diffuse large B-cell lymphoma (AR-DLBCL) remains a prominent cancer among individuals living with HIV with a suboptimal prognosis. Identifying independent prognostic markers could improve risk stratification.
    Methods: In this multicenter retrospective cohort study spanning years 2011 to 2019, 153 eligible patients with AR-DLBCL were examined. Overall survival (OS) factors were analyzed using Kaplan-Meier curves, and univariate and multivariate Cox proportional hazards models. The discriminatory ability of the risk score was evaluated by examining the area under the receiver operating characteristic curve.
    Results: The study included 153 patients with a median age of 47 years (interquartile range [IQR] 39-58), 83.7% of whom were men. The median follow-up was 12.0 months (95% confidence interval [CI], 8.5-15.5), with an OS rate of 35.9%. Among the potential inflammatory markers examined, only the ratio of hemoglobin (g/dL) to red cell distribution width (%) (Hb/RDW) emerged as an independent prognostic parameter for OS in the training (hazard ratios [HR] = 2.645, 95% CI = 1.267-5.522,
    Conclusion: We identified a cost-effective and readily available inflammatory biomarker, the Hb/RDW ratio, as an independent predictor of outcomes in patients with AR-DLBCL. Its integration into the IPI score partially improves prognostic accuracy.
    MeSH term(s) Female ; Humans ; Male ; Middle Aged ; Acquired Immunodeficiency Syndrome ; Erythrocyte Indices ; Hemoglobins ; Lymphoma, Large B-Cell, Diffuse/pathology ; Prognosis ; Retrospective Studies ; Adult
    Chemical Substances Hemoglobins
    Language English
    Publishing date 2024-02-15
    Publishing country Switzerland
    Document type Multicenter Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2024.1354325
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Association between fear of progression and sleep quality in patients with chronic heart failure: A cross-sectional study.

    Xiong, Juanjuan / Qin, Jingwen / Gong, Kaizheng

    Journal of advanced nursing

    2023  Volume 79, Issue 8, Page(s) 3082–3091

    Abstract: Aims: This study aimed to measure sleep quality and its possible association with fear of progression (FOP) in patients with chronic heart failure (HF).: Design: A cross-sectional study.: Methods: A total of 254 patients with chronic HF were ... ...

    Abstract Aims: This study aimed to measure sleep quality and its possible association with fear of progression (FOP) in patients with chronic heart failure (HF).
    Design: A cross-sectional study.
    Methods: A total of 254 patients with chronic HF were recruited from two tertiary hospitals in China. The sociodemographic and clinical data of participants were collected using a general information questionnaire. The Pittsburgh Sleep Quality Index and Fear of Progression Questionnaire-Short Form were used to evaluate sleep quality over 1 month and FOP. Pearson correlation and hierarchical regression were conducted to analyse the relationship between sleep quality and FOP.
    Results: Of all participants, 85.8% had poor sleep quality, with a mean score of 12.3 ± 4.2 (possible score could be 0 to 21). The severity of FOP was positively correlated with poor sleep quality. HF hospitalization in the past year, numbers of HF drugs, monthly income and total score of FOP were strong predictors of decreased sleep quality, accounting for 24.2% of the variance in the sleep quality of these patients.
    Conclusions: Patients with chronic HF generally reported poor sleep quality, which should be highly concerned for medical workers. Alleviating FOP as a therapeutic strategy may improve sleep quality.
    Impact: It is urgent to raise clinical attention that Chinese patients with chronic HF have poor sleep quality, which is not just due to the symptoms of HF itself. FOP is an important psychological factor influencing sleep quality in patients with chronic HF, which has not been explored in China. This study provides a new perspective on targeted interventions for poor sleep quality in chronic HF.
    Patient and public involvement: No patient or public involvement.
    MeSH term(s) Humans ; Cross-Sectional Studies ; Sleep Quality ; Fear/psychology ; Chronic Disease ; Surveys and Questionnaires ; Heart Failure/complications ; Heart Failure/psychology
    Language English
    Publishing date 2023-03-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 197634-5
    ISSN 1365-2648 ; 0309-2402
    ISSN (online) 1365-2648
    ISSN 0309-2402
    DOI 10.1111/jan.15657
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Impact of evidence-based nursing on postoperative psychological state, quality of life, and function of affected limbs in breast cancer patients: An observational study.

    Wang, Shaoman / He, Peijuan / Liu, Qin / Mao, Juanjuan / Shen, Songna

    Medicine

    2024  Volume 103, Issue 1, Page(s) e36788

    Abstract: To analyze the effect of evidence-based nursing on postoperative psychological state, quality of life, and function of affected limbs in breast cancer (BC) patients. This study is a retrospective analysis. The clinical data of 122 BC patients in our ... ...

    Abstract To analyze the effect of evidence-based nursing on postoperative psychological state, quality of life, and function of affected limbs in breast cancer (BC) patients. This study is a retrospective analysis. The clinical data of 122 BC patients in our hospital were selected and divided into evidence-based group and routine group according to different nursing programs. Patients in evidence-based group received evidence-based nursing, and patients in the conventional group received routine nursing intervention. The acceptance level of BC diagnosis in evidence-based group was significantly higher than that in the conventional group, showing statistical significance (P < .05). After intervention, Self-rating Anxiety Scale and Self-rating Depression Scale scores of both groups were significantly reduced, and the Self-rating Anxiety Scale and Self-rating Depression Scale scores in evidence-based group were significantly lower than those in conventional group, showing statistically significant difference (P < .05); Self-Esteem Scale scores were significantly increased in both groups after intervention, and the scores in evidence-based group were significantly higher than those in conventional group, showing statistically significant difference (P < .05). After intervention, in evidence-based group, the proportion of patients without edema was significantly increased, while the proportion of patients with mild, moderate and severe edema was significantly decreased, exhibiting statistically significant difference (P < .05). After intervention, the circumference difference of the healthy side and the affected side decreased significantly, which was much lower in evidence-based group, showing statistically significant difference (P < .05). After intervention, range of motion of the upper limbs increased significantly between the 2 groups, which was much higher in evidence-based group, exhibiting statistical significance (P < .05). The scores of quality of life (role, emotion, body, cognition and society dimension) in evidence-based group were higher than those in conventional group, exhibiting statistically significant difference (P < .05). Evidence-based nursing can develop more targeted nursing measures according to patients' problems, thus effectively promoting the recovery of upper limb function of BC patients after surgery.
    MeSH term(s) Humans ; Female ; Quality of Life ; Breast Neoplasms/surgery ; Evidence-Based Nursing ; Retrospective Studies ; Upper Extremity ; Edema
    Language English
    Publishing date 2024-01-05
    Publishing country United States
    Document type Observational Study ; Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000036788
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Retraction Note: LncRNA SNHG7 promotes pancreatic cancer proliferation through ID4 by sponging miR-342-3p.

    Cheng, Dongfeng / Fan, Juanjuan / Ma, Yang / Zhou, Yiran / Qin, Kai / Shi, Minmin / Yang, Jingrui

    Cell & bioscience

    2023  Volume 13, Issue 1, Page(s) 149

    Language English
    Publishing date 2023-08-14
    Publishing country England
    Document type Retraction of Publication
    ZDB-ID 2593367-X
    ISSN 2045-3701
    ISSN 2045-3701
    DOI 10.1186/s13578-023-01103-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Interaction between curcumin and ultrafiltered casein micelles or whey protein, and characteristics of their complexes.

    Wu, Hao / Qin, Juanjuan / Ji, Wei / Palupi, Niken Widya / Yang, Min

    Journal of food science

    2024  Volume 89, Issue 3, Page(s) 1582–1598

    Abstract: This work evaluated the interaction between micellar casein (MC) or whey protein (WP) in ultrafiltration retentate with curcumin (Cur), as well as the physicochemical and functional properties of Cur-MC and Cur-WP complexes. The MC had a higher affinity ... ...

    Abstract This work evaluated the interaction between micellar casein (MC) or whey protein (WP) in ultrafiltration retentate with curcumin (Cur), as well as the physicochemical and functional properties of Cur-MC and Cur-WP complexes. The MC had a higher affinity for Cur than WP, shown by higher binding constants of Cur-MC at various temperatures. Thermodynamic analysis of the binding process indicated that the interaction between Cur and MC or WP was hydrophobic in nature. Cur promoted the size and polydispersity index of MC and WP at 4 mM but did not alter the morphology of spray-dried MC and WP. The Cur-MC complexes showed better aqueous solubility at pH 2-3 and 6-10 compared to free MC. Combination with MC or WP improved the 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonate) radical scavenging activity of Cur. In addition, combination with MC and WP promoted cumulative release of Cur during simulated gastrointestinal digestion, especially for WP. Thus, MC and WP in retentates can be good alternative protein-based carriers for Cur delivery, whereas their complexes in powder form have good functional properties that could be used as active food ingredients in several food formulations. PRACTICAL APPLICATION: Microfiltration is a cheap and convenient approach that can be used to easily produce micellar casein (MC), with whey protein (WP) as one byproduct. In this study, we proved that MC and WP in retentates have strong interaction with curcumin (Cur), whereas their complexes have good functional properties. Thus, spray-dried MC-Cur or WP-Cur complexes could be used as active food ingredients in several food formulations.
    MeSH term(s) Micelles ; Curcumin/chemistry ; Caseins/chemistry ; Whey Proteins ; Food Ingredients
    Chemical Substances Micelles ; Curcumin (IT942ZTH98) ; Caseins ; Whey Proteins ; Food Ingredients
    Language English
    Publishing date 2024-02-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241615-3
    ISSN 1750-3841 ; 0022-1147
    ISSN (online) 1750-3841
    ISSN 0022-1147
    DOI 10.1111/1750-3841.16959
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  9. Article ; Online: A nomogram to predict the risk of sarcopenia in older people.

    Yin, Guangjiao / Qin, Juanjuan / Wang, Ziwei / Lv, Fang / Ye, Xujun

    Medicine

    2023  Volume 102, Issue 16, Page(s) e33581

    Abstract: The burden of sarcopenia is increasing worldwide. However, most cases of sarcopenia are undiagnosed due to the lack of simple screening tools. This study aimed to develop and validate an individualized and simple nomogram for predicting sarcopenia in ... ...

    Abstract The burden of sarcopenia is increasing worldwide. However, most cases of sarcopenia are undiagnosed due to the lack of simple screening tools. This study aimed to develop and validate an individualized and simple nomogram for predicting sarcopenia in older adults. A total of 180 medical examination populations aged ≥60 years were enrolled in this study. Sarcopenia was diagnosed according to the Asian Working Group for Sarcopenia 2019 consensus. The primary data were randomly divided into training and validation sets. Univariate logistic regression analysis was performed to select the risk factors of sarcopenia, which were subjected to the least absolute shrinkage and selection operator for feature selection. A nomogram was established using multivariate logistic regression analysis by incorporating the features selected in the least absolute shrinkage and selection operator regression model. The discrimination and calibration of the predictive model were verified by the concordance index, receiver operating characteristic curve, and calibration curve. In this study, 55 cases of sarcopenia were available. Risk predictors included age, albumin, blood urea nitrogen, grip strength, and calf circumference. The model had good discrimination and calibration capabilities. concordance index was 0.92 (95% confidence interval: 0.84-1.00), and the area under the receiver operating characteristic curve was 0.92 (95% confidence interval: 0.83-1.00) in the validation set. The Hosmer-Lemeshow test had a P value of .94. The predictive model in this study will be a clinically useful tool for predicting the risk of sarcopenia, and it will facilitate earlier detection and therapeutic intervention for sarcopenia.
    MeSH term(s) Aged ; Humans ; Albumins ; Blood Urea Nitrogen ; Nomograms ; Sarcopenia/diagnosis ; Sarcopenia/epidemiology ; Risk Assessment ; China/epidemiology ; Middle Aged ; East Asian People/statistics & numerical data
    Chemical Substances Albumins
    Language English
    Publishing date 2023-04-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000033581
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Follow-up survey of general practitioners in Zhejiang Province post-completion of position transition training in 2017-2020.

    Qin, Hongli / Li, Shuai / Liu, Juanjuan / Ren, Jingjing / Yu, Meiyue

    BMC medical education

    2023  Volume 23, Issue 1, Page(s) 182

    Abstract: Background: Position transition training for general practitioners in Zhejiang Province started in 2017 and has since been held once a year. By the beginning of 2022, four training sessions were completed. The purpose of this survey was to establish the ...

    Abstract Background: Position transition training for general practitioners in Zhejiang Province started in 2017 and has since been held once a year. By the beginning of 2022, four training sessions were completed. The purpose of this survey was to establish the current situation of trainees after their graduation and provide reference for the evaluation of the training effect.
    Methods: Of the 738 trainees who completed the training, 253 were contacted and followed up. A self-designed questionnaire was used to conduct the survey through online filling in. The content included questions to elucidate the following information: whereabouts after the training, registration as a general practitioner, undertaken general practice teaching and scientific research work, current occupational environment, improvement of post competence after receiving position transition training, willingness to complete survey, willingness to participate in future training programs, etc. RESULTS: A number of 253 valid questionnaires were collected with a recovery rate of 100%. Notably, 93.68% of the participants successfully completed their training and obtained the Training Certificate of General Practitioners. Further, 83.4% were registered as general practitioners, 82.94% of which added on the basis of the original registered scope of practice. Currently, most of them work in primary health care institutions, primarily occupied with medical treatment, chronic disease management, COVID-19 prevention and control, health education, and prevention and health care. Of them, 27.01% were currently undertaking teaching work, and only 3.32% of them were conducting scientific research work related to general practice. The overall satisfaction of the trainees in the three theoretical training bases was above 90%, with no statistically significant difference among them (P > 0.05). Importantly, 84.11% of the followed-up personnel hoped to continue to participate in similar training in the future to improve their general practitioner core competences.
    Conclusion: The position transition training in Zhejiang Province has achieved good results, but the details of training and the implementation of policies in individual regions need to be improved. Most of the graduates were willing to continue their education, especially in general practitioners with special interests.
    MeSH term(s) Humans ; General Practitioners/education ; Follow-Up Studies ; COVID-19 ; General Practice/education ; Surveys and Questionnaires
    Language English
    Publishing date 2023-03-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2044473-4
    ISSN 1472-6920 ; 1472-6920
    ISSN (online) 1472-6920
    ISSN 1472-6920
    DOI 10.1186/s12909-023-04151-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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