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  1. Article: Ischemic Stroke in a Young Man: Unraveling the Domain of Myeloproliferative Disorders.

    Hamid, Muhammad Ammar B / Sehbai, Aasim S / Tariq, Shahan

    Cureus

    2021  Volume 13, Issue 7, Page(s) e16495

    Abstract: Ischemic stroke is a rare phenomenon in young adults. A complete workup for hypercoagulable and myeloproliferative disorders is a cornerstone of evaluation. Essential thrombocytosis is a chronic myeloproliferative disorder that primarily involves ... ...

    Abstract Ischemic stroke is a rare phenomenon in young adults. A complete workup for hypercoagulable and myeloproliferative disorders is a cornerstone of evaluation. Essential thrombocytosis is a chronic myeloproliferative disorder that primarily involves platelets. It may remain undiagnosed in patients and subsequently present in the form of ischemic stroke. The management of this disorder is complex and often involves cytoreduction therapies. The initiation of these drugs in such patients may lead to unnecessary adverse effects and complications. This case report is an attempt to highlight an underappreciated cause of stroke when assessing young individuals.
    Language English
    Publishing date 2021-07-19
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.16495
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: COVID-19 Vaccination in<br /> Pregnant Women: Exploring Serious Adverse Events.

    Tariq, Shahan / Hamid, Muhammad Ammar Bin / Sehbai, Aasim

    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

    2023  Volume 33, Issue 2, Page(s) 243–244

    Abstract: Null. ...

    Abstract Null.
    MeSH term(s) Female ; Humans ; Pregnancy ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Pregnant Women ; Vaccination/adverse effects
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2023-02-16
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 2276646-7
    ISSN 1681-7168 ; 1022-386X
    ISSN (online) 1681-7168
    ISSN 1022-386X
    DOI 10.29271/jcpsp.2023.02.243
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6532: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Unusual presentation of gastric cancer during treatment of hairy cell leukemia: Exploring the etiological basis of this rare phenomenon.

    Tariq, Shahan / Bin Hamid, Muhammad Ammar / Rahman, Nazia / Oleary, Lindsey / Wong, Kristine / Sehbai, Aasim

    Cancer pathogenesis and therapy

    2023  Volume 1, Issue 2, Page(s) 146–148

    Abstract: Hairy cell leukemia (HCL) is a rare B-cell lymphoproliferative disorder. Patients typically present with cytopenia and splenomegaly. We describe the case of a 78-year-old patient with refractory HCL who acutely developed a cystic lesion on the back while ...

    Abstract Hairy cell leukemia (HCL) is a rare B-cell lymphoproliferative disorder. Patients typically present with cytopenia and splenomegaly. We describe the case of a 78-year-old patient with refractory HCL who acutely developed a cystic lesion on the back while receiving moxetumomab pasudotox therapy. Biopsy of the lesion revealed the presence of adenocarcinoma, which prompted a detailed evaluation resulting in a diagnosis of stage IV gastric cancer. Nevertheless, to establish any association between moxetumomab pasudotox therapy and secondary cancer development, a satisfactory number of studies need to be conducted.
    Language English
    Publishing date 2023-01-12
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2949-7132
    ISSN (online) 2949-7132
    DOI 10.1016/j.cpt.2023.01.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Recurrence Risk of Renal Cell Carcinoma Lingers Even Decades After Nephrectomy.

    Hamid, Muhammad Ammar B / Sehbai, Aasim / Tariq, Shahan / Ullah, Sana

    Cureus

    2021  Volume 13, Issue 8, Page(s) e17217

    Abstract: Renal cell carcinoma (RCC) is a common malignancy in elderly males. Metastatic spread of this cancer is not an uncommon occurrence, even after nephrectomy. Lung, bone, liver, and brain are the most frequently involved sites. Such a type of presentation ... ...

    Abstract Renal cell carcinoma (RCC) is a common malignancy in elderly males. Metastatic spread of this cancer is not an uncommon occurrence, even after nephrectomy. Lung, bone, liver, and brain are the most frequently involved sites. Such a type of presentation mostly occurs within five years after nephrectomy however, cases have been reported later as well. Here, we report a case of metastatic renal cell carcinoma that presented in the form of a lung growth 28 years after nephrectomy. This highlights the importance to consider relapsed metastatic renal cancer in the differential, even decades after its surgical removal.
    Language English
    Publishing date 2021-08-16
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.17217
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Perioperative management of a patient with May-Hegglin anomaly requiring craniotomy.

    Sehbai, Aasim S / Abraham, Jame / Brown, Vidya K

    American journal of hematology

    2005  Volume 79, Issue 4, Page(s) 303–308

    Abstract: May-Hegglin anomaly (MHA) is a rare type of autosomal dominant platelet disorder associated with mutations in the gene encoding nonmuscle myosin heavy chain 9 (MYH9). It is characterized by the presence of large platelets, leukocyte inclusions, and ... ...

    Abstract May-Hegglin anomaly (MHA) is a rare type of autosomal dominant platelet disorder associated with mutations in the gene encoding nonmuscle myosin heavy chain 9 (MYH9). It is characterized by the presence of large platelets, leukocyte inclusions, and thrombocytopenia. The bleeding tendency is usually mild, but severe hemorrhages have been reported. This is the first reported case of a patient with MHA who underwent craniotomy for intractable seizure disorder of temporal lobe origin. Patients who have thrombocytopenia have a higher likelihood of developing intraoperative or postoperative intracranial hematoma and bleeding complications. The patient was administered desmopressin (DDAVP) prior to the neurosurgical procedure and had no complications. With this approach, the use of platelet concentrates could be avoided. We discuss the role of DDAVP in MHA and related platelet disorders and review the current literature.
    MeSH term(s) Adult ; Blood Loss, Surgical/prevention & control ; Craniotomy ; Deamino Arginine Vasopressin/administration & dosage ; Deamino Arginine Vasopressin/therapeutic use ; Epilepsy/blood ; Epilepsy/complications ; Epilepsy/surgery ; Female ; Hemostatics/administration & dosage ; Hemostatics/therapeutic use ; Humans ; Pedigree ; Perioperative Care/methods ; Platelet Count ; Platelet Transfusion ; Thrombocytopenia/blood ; Thrombocytopenia/complications ; Thrombocytopenia/genetics ; Thrombocytopenia/surgery ; Treatment Outcome
    Chemical Substances Hemostatics ; Deamino Arginine Vasopressin (ENR1LLB0FP)
    Language English
    Publishing date 2005-08
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 196767-8
    ISSN 1096-8652 ; 0361-8609
    ISSN (online) 1096-8652
    ISSN 0361-8609
    DOI 10.1002/ajh.20446
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1251: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Rhabdomyolysis and renal failure associated with gemfibrozil monotherapy.

    Layne, Richard D / Sehbai, Aasim S / Stark, Linda J

    The Annals of pharmacotherapy

    2004  Volume 38, Issue 2, Page(s) 232–234

    Abstract: Objective: To report a case of rhabdomyolysis and acute renal failure associated with gemfibrozil monotherapy of hyperlipidemia.: Case summary: A 30-year-old white man with hypertension, type 1 diabetes mellitus, and hyperlipidemia was hospitalized ... ...

    Abstract Objective: To report a case of rhabdomyolysis and acute renal failure associated with gemfibrozil monotherapy of hyperlipidemia.
    Case summary: A 30-year-old white man with hypertension, type 1 diabetes mellitus, and hyperlipidemia was hospitalized due to myalgias, nausea, and vomiting that began after he started working as a jackhammer operator 4 days previously. His medications were lisinopril, aspirin, insulin, and gemfibrozil. Creatine kinase and creatinine, which previously had been mildly elevated and normal, respectively, were markedly elevated, consistent with rhabdomyolysis with acute renal failure.
    Discussion: As of December 8, 2003, this is the only report of a patient with normal baseline creatinine level who developed rhabdomyolysis with acute renal failure associated with gemfibrozil monotherapy. Strenuous exertion, hypovolemia, and lisinopril use may have contributed to the severity of illness. An objective causality assessment revealed that an adverse drug reaction to gemfibrozil was possible.
    Conclusions: Gemfibrozil monotherapy of hyperlipidemia may predispose to rhabdomyolysis with acute renal failure. Patients using gemfibrozil should be cautioned regarding strenuous exertion, dehydration, and the need for prompt evaluation of myalgias.
    MeSH term(s) Acute Kidney Injury/chemically induced ; Adult ; Creatinine/blood ; Diabetes Mellitus, Type 1/complications ; Gemfibrozil/adverse effects ; Humans ; Hyperlipidemias/complications ; Hyperlipidemias/drug therapy ; Hypertension/complications ; Hypolipidemic Agents/adverse effects ; Male ; Physical Exertion ; Rhabdomyolysis/chemically induced ; Rhabdomyolysis/physiopathology
    Chemical Substances Hypolipidemic Agents ; Creatinine (AYI8EX34EU) ; Gemfibrozil (Q8X02027X3)
    Language English
    Publishing date 2004-02
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1101370-9
    ISSN 1542-6270 ; 1060-0280
    ISSN (online) 1542-6270
    ISSN 1060-0280
    DOI 10.1345/aph.1D282
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 900: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Thymic hyperplasia after adjuvant chemotherapy in breast cancer.

    Sehbai, Aasim S / Tallaksen, Robert J / Bennett, Jason / Abraham, Jame

    Journal of thoracic imaging

    2006  Volume 21, Issue 1, Page(s) 43–46

    Abstract: We report 2 patients with breast cancer who were treated with surgery and adjuvant chemotherapy for stage IIa and stage I breast cancers. Follow-up CT scans showed an anterior mediastinal mass, raising concern for tumor recurrence. Thymectomy performed ... ...

    Abstract We report 2 patients with breast cancer who were treated with surgery and adjuvant chemotherapy for stage IIa and stage I breast cancers. Follow-up CT scans showed an anterior mediastinal mass, raising concern for tumor recurrence. Thymectomy performed on the first patient, and close follow-up with radiographic studies on the second patient, revealed benign thymic enlargement. Thymic hyperplasia can occur after cytotoxic chemotherapy and may be due to rebound enlargement after initial atrophy caused by chemotherapy. Thymic hyperplasia after chemotherapy has been reported mostly in young age groups and is described in the literature to be associated with various types of cancers, including lymphomas, leukemias, testicular cancer, and sarcomas, and in the stem cell transplant setting. This is the first case series describing 2 patients with early stage breast cancer who, following adjuvant standard dose chemotherapy, developed thymic hyperplasia. Awareness of this unusual side effect in patients treated with chemotherapy may prevent unnecessary investigation and surgical intervention.
    MeSH term(s) Adult ; Breast Neoplasms/complications ; Breast Neoplasms/drug therapy ; Breast Neoplasms/surgery ; Chemotherapy, Adjuvant/adverse effects ; Diagnosis, Differential ; Female ; Follow-Up Studies ; Humans ; Middle Aged ; Thymectomy/methods ; Thymus Hyperplasia/chemically induced ; Thymus Hyperplasia/diagnosis ; Tomography, X-Ray Computed/methods
    Language English
    Publishing date 2006-03
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 632900-7
    ISSN 1536-0237 ; 0883-5993
    ISSN (online) 1536-0237
    ISSN 0883-5993
    DOI 10.1097/01.rti.0000185143.17436.f9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2187: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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