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Article: Sleep and nutritional profile of endurance and ultra-endurance running athletes.

Dos Santos, Nadia Esteves / Daniel, Natalia Vilela Silva / Franco, Beatriz / Bastos, Andre Marana / Belli, Taisa / Esteves, Andrea Maculano

Sleep science (Sao Paulo, Brazil)

2022 Volume 15, Issue 4, Page(s) 441–447

Abstract: Sleeping and eating before and during an ultramarathon can directly affect an athlete's performance, who may also have their physiological adaptations and recovery process hindered by sleeping problems. Endurance and ultra-endurance athletes may have ... ...

Abstract	Sleeping and eating before and during an ultramarathon can directly affect an athlete's performance, who may also have their physiological adaptations and recovery process hindered by sleeping problems. Endurance and ultra-endurance athletes may have different sleep and nutrition profiles. Thus, this study aimed to describe the sleep profile (during preparation) and nutritional profile (during competition) of endurance (10-20km) and ultra-endurance (50-100km) running athletes. For this, 16 healthy volunteers answered questionnaires related to sleep quality (Pittsburgh sleep quality index), chronotype (morningness-eveningness questionnaire), and sleepiness (excessive daytime sleepiness questionnaire). Immediately after a competition, a form prepared by the research team about nutritional variables and volunteers' food records during the competition was applied. According to test scoring criteria (Pittsburgh sleep quality index >5; sleepiness >10), endurance running athletes showed low sleep quality. In addition, all athletes showed consumption of carbohydrates and lipids below the recommended, but excessive consumption of proteins. A positive association between sleepiness and sodium intake in endurance runners was observed (r=0.862;
Language	English
Publishing date	2022-11-19
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2697016-8
ISSN	1984-0063 ; 1984-0659
ISSN (online)	1984-0063
ISSN	1984-0659
DOI	10.5935/1984-0063.20220076
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Multi-Targeting Approach in Glioblastoma Using Computer-Assisted Drug Discovery Tools to Overcome the Blood-Brain Barrier and Target EGFR/PI3Kp110β Signaling.

Franco, Catarina / Kausar, Samina / Silva, Margarida F B / Guedes, Rita C / Falcao, Andre O / Brito, Maria Alexandra

Cancers

2022 Volume 14, Issue 14

Abstract: The epidermal growth factor receptor (EGFR) is upregulated in glioblastoma, becoming an attractive therapeutic target. However, activation of compensatory pathways generates inputs to downstream PI3Kp110β signaling, leading to anti-EGFR therapeutic ... ...

Abstract	The epidermal growth factor receptor (EGFR) is upregulated in glioblastoma, becoming an attractive therapeutic target. However, activation of compensatory pathways generates inputs to downstream PI3Kp110β signaling, leading to anti-EGFR therapeutic resistance. Moreover, the blood-brain barrier (BBB) limits drugs' brain penetration. We aimed to discover EGFR/PI3Kp110β pathway inhibitors for a multi-targeting approach, with favorable ADMET and BBB-permeant properties. We used quantitative structure-activity relationship models and structure-based virtual screening, and assessed ADMET properties, to identify BBB-permeant drug candidates. Predictions were validated in in vitro models of the human BBB and BBB-glioma co-cultures. The results disclosed 27 molecules (18 EGFR, 6 PI3Kp110β, and 3 dual inhibitors) for biological validation, performed in two glioblastoma cell lines (U87MG and U87MG overexpressing EGFR). Six molecules (two EGFR, two PI3Kp110β, and two dual inhibitors) decreased cell viability by 40-99%, with the greatest effect observed for the dual inhibitors. The glioma cytotoxicity was confirmed by analysis of targets' downregulation and increased apoptosis (15-85%). Safety to BBB endothelial cells was confirmed for three of those molecules (one EGFR and two PI3Kp110β inhibitors). These molecules crossed the endothelial monolayer in the BBB in vitro model and in the BBB-glioblastoma co-culture system. These results revealed novel drug candidates for glioblastoma treatment.
Language	English
Publishing date	2022-07-19
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527080-1
ISSN	2072-6694
ISSN	2072-6694
DOI	10.3390/cancers14143506
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Article ; Online: Dry matter accumulation and macronutrient uptake in sugarcane varieties

Santana, Rafaela Silva / Mauad, Munir / de Medeiros, Elias Silva / Silva, Paulo Vinicius / Mussury Franco Silva, Rosilda Mara / Goneli, Andre Luis Duarte

Journal of Plant Nutrition. 2023 Aug. 27, v. 46, no. 14 p.3385-3401

2023

Abstract: The increase of the area cultivated with sugarcane has demanded information about the culture, mainly in relation to its nutritional needs. There are few studies that report the nutrient uptake in sugarcane, in addition, there are no reports of studies ... ...

Abstract	The increase of the area cultivated with sugarcane has demanded information about the culture, mainly in relation to its nutritional needs. There are few studies that report the nutrient uptake in sugarcane, in addition, there are no reports of studies focused on the different periods of sugarcane growth and development. In view of the above, the objective of this research was to determine the macronutrient uptake and dry matter production in the shoots of two sugarcane varieties. The experiment was carried out in Vicentina, Mato Grosso do Sul, Brazil, during the 2017/2018 harvest, using two varieties of sugarcane (RB92579 and SP832847). The experimental design was in randomized blocks with two sugarcane varieties, nine collecting times (90, 120, 150, 180, 210, 240, 270, 300 and 330 days after planting (DAP) and 4 replications. Samples were collected from the shoots of 10 plants, which were divided into leaves, sheaths and stalks, then dried and weighed, and finally the samples were submitted to laboratory analysis to determine the nutrient concentrations in each organ. The accumulation of macronutrients in the shoots of both varieties followed the order: K > N > Ca > S>Mg > P. The export by the stalk followed the order K > N > Ca > S > P > Mg for RB92579 and K > N > Ca = P > S > Mg for SP832847. Maximum accumulation of nutrients and the maximum dry matter production occurred in the interval between 240 and 300 DAP. The variety SP832847 accumulated higher amounts of nutrients and dry matter in relation to RB92579, as well as the time required for the maximum accumulation was shorter.
Keywords	dry matter accumulation ; experimental design ; exports ; growth and development ; nutrient uptake ; plant nutrition ; sugarcane ; Brazil ; Mineral nutrition ; nutrient partitioning ; phytomass production ; Saccharum spp
Language	English
Dates of publication	2023-0827
Size	p. 3385-3401.
Publishing place	Taylor & Francis
Document type	Article ; Online
ZDB-ID	446190-3
ISSN	1532-4087 ; 0190-4167
ISSN (online)	1532-4087
ISSN	0190-4167
DOI	10.1080/01904167.2023.2205519
Database	NAL-Catalogue (AGRICOLA)

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Article: Biological activity of nine recombinant AtRALF peptides: Implications for their perception and function in Arabidopsis

Morato do Canto, Amanda / Antonio Augusto Franco Garcia / Bianca Ribeiro / Daniel S. Moura / Fausto AndrÃ©s Ortiz Morea / Marcio C. Silva-Filho / Paulo H.O. Ceciliato

Plant physiology and biochemistry. 2014 Feb., v. 75

2014

Abstract: RALF is a small (5Â kDa) and ubiquitous plant peptide signal. It was first isolated from tobacco leaf protein extracts owing to its capacity to alkalinize the extracellular media of cell suspensions. RALFs inhibit root growth and hypocotyl elongation, ... ...

Abstract	RALF is a small (5Â kDa) and ubiquitous plant peptide signal. It was first isolated from tobacco leaf protein extracts owing to its capacity to alkalinize the extracellular media of cell suspensions. RALFs inhibit root growth and hypocotyl elongation, and a role for RALFs in cell expansion has also been proposed. Arabidopsis has 37 RALF isoforms (AtRALF), but only a small group of nine has high primary structure identity to the original RALF peptide isolated from tobacco. Herein, we report the heterologous production of these nine peptides in Escherichia coli and the evaluation of their activity in five biological assays. All AtRALF peptides produced showed strong alkalinizing activities, with the exception of the pollen-specific isoform AtRALF4. Although it exhibited no inhibitory activity in the root growth and hypocotyl elongation assays, AtRALF4 is a strong inhibitor of pollen germination. Our data demonstrate that the divergence in the tissue specificity and gene expression patterns of the different AtRALFs does not change the fact that their main role seems to be the regulation of cell expansion. Furthermore, different activities in the alkalinization assays upon the addition of two consecutive and saturating doses of the peptides suggest that the peptides are likely being sensed by specific receptors.
Keywords	alkalinization ; Arabidopsis ; bioactive properties ; bioassays ; cell suspension culture ; Escherichia coli ; gene expression regulation ; hypocotyls ; leaf protein ; peptides ; pollen germination ; receptors ; root growth ; signal peptide ; tobacco
Language	English
Dates of publication	2014-02
Size	p. 45-54.
Publishing place	Elsevier Masson SAS
Document type	Article
ZDB-ID	742978-2
ISSN	1873-2690 ; 0981-9428
ISSN (online)	1873-2690
ISSN	0981-9428
DOI	10.1016/j.plaphy.2013.12.005
Database	NAL-Catalogue (AGRICOLA)

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Article: Sleep and nutritional profile of endurance and ultra-endurance running athletes

Santos, Nadia Esteves dos / Daniel, Natalia Vilela Silva / Franco, Beatriz / Bastos, Andre Marana / Belli, Taisa / Esteves, Andrea Maculano

Sleep Science

2022 Volume 15, Issue 04, Page(s) 441–447

Abstract: Sleeping and eating before and during an ultramarathon can directly affect an athlete’s performance, who may also have their physiological adaptations and recovery process hindered by sleeping problems. Endurance and ultra-endurance athletes may have ... ...

Abstract	Sleeping and eating before and during an ultramarathon can directly affect an athlete’s performance, who may also have their physiological adaptations and recovery process hindered by sleeping problems. Endurance and ultra-endurance athletes may have different sleep and nutrition profiles. Thus, this study aimed to describe the sleep profile (during preparation) and nutritional profile (during competition) of endurance (10-20km) and ultra-endurance (50-100km) running athletes. For this, 16 healthy volunteers answered questionnaires related to sleep quality (Pittsburgh sleep quality index), chronotype (morningness-eveningness questionnaire), and sleepiness (excessive daytime sleepiness questionnaire). Immediately after a competition, a form prepared by the research team about nutritional variables and volunteers’ food records during the competition was applied. According to test scoring criteria (Pittsburgh sleep quality index >5; sleepiness >10), endurance running athletes showed low sleep quality. In addition, all athletes showed consumption of carbohydrates and lipids below the recommended, but excessive consumption of proteins. A positive association between sleepiness and sodium intake in endurance runners was observed (r=0.862; p =0.027). Sleep efficiency and race time showed a negative correlation only for ultra-endurance athletes (r=-0.834; p =0.039). The data obtained show that endurance athletes presented more sleep pattern alterations, however, endurance and ultra-endurance athletes showed inadequate nutritional consumption during the competition.
Keywords	Running ; Athletes ; Sleep ; Nutrition Personnel
Language	English
Publishing date	2022-12-01
Publisher	Thieme Revinter Publicações Ltda.
Publishing place	Stuttgart ; New York
Document type	Article
ZDB-ID	2697016-8
ISSN	1984-0063 ; 1984-0659 ; 1984-0063
ISSN (online)	1984-0063
ISSN	1984-0659 ; 1984-0063
DOI	10.5935/1984-0063.20220076
Database	Thieme publisher's database

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Article ; Online: Analysis of in vitro activity of high dilutions of Euphorbia tirucalli L. in human melanoma cells

Teresa Cristina Andrade Leitao Aguiar / AndrÃƒÂ�� Luiz Franco Sampaio / DulcinÃƒÂ©ia Furtado Teixeira / Renata Macedo dos Reis JanuÃƒÂ¡rio da Silva

International Journal of High Dilution Research, Vol 10, Iss 36, Pp 183-

2011 Volume 193

Abstract: Aveloz (firestick cactus; Euphorbia tirucalli L.) belongs to Euphorbiaceae family, characterized by the production of a toxic latex that has corrosive effects on the skin and mucous membranes. Continual topic use of the latex is recommended by popular ... ...

Abstract	Aveloz (firestick cactus; Euphorbia tirucalli L.) belongs to Euphorbiaceae family, characterized by the production of a toxic latex that has corrosive effects on the skin and mucous membranes. Continual topic use of the latex is recommended by popular medicine to treat warts, and epitheliomas. To validate this indication, ultra diluted latex and homeopathic medicine Euphorbia tirucalli were tested in vitro on the proliferation of melanoma cells. Ultra diluted latex was prepared in homeopathic dilutions 5cH, 15cH and 30cH by dilution and agitation (trituration for solid and sucussion for liquid phases) using 70Ã‚Âº GL (Gay Lussac) ethylic alcohol (70Ã‚Âº GL EtOH 70Ã‚ÂºGL) as inert medium according to the guidelines in FarmacopÃƒÂ©ia HomeopÃƒÂ¡tica Brasileira (FHB). Homeopathic medicine Euphorbia tirucalli was prepared from mother-tincture according to the centesimal Hahnemannian method. Solutions 0.5% and 5% of 70Ã‚ÂºGL EtOH were succussed and used as control. Human melanoma cells were cultured, treated and monitored by method MTT for 24 to 72 hours. It was observed that 0.5% 70Ã‚ÂºGL EtOH solution had little or no effect on the proliferation of melanoma cells (5.1% maximal inhibition in dilution 30cH). Positive correlation was observed in most groups between inhibition of proliferation and diluted preparations, maximal increase (9%) was seen in with 5% latex. Moreover, mother-tincture proved to be more active than latex; treatment with 0.5% solution of latex 30cH exhibited 19.7% inhibition, whereas treatment with 0.5% solution of Euphorbia tirucalli 30cH exhibited 32.1% inhibition of cell proliferation (p<0.05). These results suggest that high dilutions of firestick cactus (especially dilution 30cH) might have a therapeutic indication in melanoma, further studies are needed in this regard.
Keywords	Euphorbia tirucalli ; High dilutions ; Antitumor activity ; Medicine (General) ; R5-920 ; Medicine ; R ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Subject code	630
Language	English
Publishing date	2011-09-01T00:00:00Z
Publisher	Universidade Estadual Paulista
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The Brazilian national prospective active surveillance (AS) cohort of patients with low-risk prostate cancer in the public health system: vigiaSUS study protocol.

Basso, Jeziel / de Lima, Juliana Beust / Bessel, Marina / Tobar Leitão, Santiago Alonso / Machado Baptista, Thais / Roithmann, Sergio / Franco Carvalhal, Eduardo / da Silva Schmitt, Caio / Morzoletto Pedrollo, Ivan / Schuch, Alice / Atalibio Hartmann, Antonio / Neubarth Estivallet, Carmen Liane / Behrend Silva Ribeiro, Guilherme / Zordan, Ricardo Andre / Isaacsson Velho, Pedro

BMC urology

2023 Volume 23, Issue 1, Page(s) 208

Abstract: Background: Prostate cancer exhibits a very diverse behaviour, with some patients dying from the disease and others never needing treatment. Active surveillance (AS) consists of periodic PSA assessment (prostate-specific antigen), DRE (digital rectal ... ...

Abstract	Background: Prostate cancer exhibits a very diverse behaviour, with some patients dying from the disease and others never needing treatment. Active surveillance (AS) consists of periodic PSA assessment (prostate-specific antigen), DRE (digital rectal examination) and periodic prostate biopsies. According to the main guidelines, AS is the preferred strategy for low-risk patients, to avoid or delay definitive treatment. However, concerns remain regarding its applicability in certain patient subgroups, such as African American men, who were underrepresented in the main cohorts. Brazil has a very racially diverse population, with 56.1% self-reporting as brown or black. The aim of this study is to evaluate and validate the AS strategy in low-risk prostate cancer patients following an AS protocol in the Brazilian public health system. Methods: This is a multicentre AS prospective cohort study that will include 200 patients from all regions of Brazil in the public health system. Patients with prostate adenocarcinoma and low-risk criteria, defined as clinical staging T1-T2a, Gleason score ≤ 6, and PSA < 10 ng/ml, will be enrolled. Archival prostate cancer tissue will be centrally reviewed. Patients enrolled in the study will follow the AS strategy, which involves PSA and physical examination every 6 months as well as multiparametric MRI (mpMRI) every two years and prostate biopsy at month 12 and then every two years. The primary objective is to evaluate the reclassification rate at 12 months, and secondary objectives include determining the treatment-free survival rate, metastasis-free survival, and specific and overall survival. Exploratory objectives include the evaluation of quality of life and anxiety, the impact of PTEN loss and the economic impact of AS on the Brazilian public health system. Discussion: This is the first Brazilian prospective study of patients with low-risk prostate cancer under AS. To our knowledge, this is one of the largest AS study cohort with a majority of nonwhite patients. We believe that this study is an opportunity to better understand the outcomes of AS in populations underrepresented in studies. Based on these data, an AS national clinical guideline will be developed, which may have a beneficial impact on the quality of life of patients and on public health. Trial registration: Clinicaltrials registration is NCT05343936.
MeSH term(s)	Male ; Humans ; Prospective Studies ; Prostate-Specific Antigen ; Brazil/epidemiology ; Watchful Waiting/methods ; Quality of Life ; Public Health ; Prostatic Neoplasms/diagnosis ; Prostatic Neoplasms/therapy
Chemical Substances	Prostate-Specific Antigen (EC 3.4.21.77)
Language	English
Publishing date	2023-12-11
Publishing country	England
Document type	Journal Article
ZDB-ID	2059857-9
ISSN	1471-2490 ; 1471-2490
ISSN (online)	1471-2490
ISSN	1471-2490
DOI	10.1186/s12894-023-01380-w
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Colistin-resistant Escherichia coli belonging to different sequence types: genetic characterization of isolates responsible for colonization, community- and healthcare-acquired infections.

Paiva, Yrving / Nagano, Debora Satie / Cotia, Andre Luis Franco / Guimarães, Thais / Martins, Roberta Cristina Ruedas / Perdigão Neto, Lauro Vieira / Côrtes, Marina Farrel / Marchi, Ana Paula / Corscadden, Louise / Machado, Anna Silva / Paula, Alexandre Inácio de / Franco, Lucas Augusto Moyses / Neves, Patricia Regina / Levin, Anna Sara / Costa, Silvia Figueiredo

Revista do Instituto de Medicina Tropical de Sao Paulo

2021 Volume 63, Page(s) e38

Abstract: The plasmid-mediated colistin-resistance gene named mcr-1 has been recently described in different countries and it became a public health challenge. Of note, few studies have addressed the spread of Escherichia coli harboring the mcr-1 gene in both, ... ...

Abstract	The plasmid-mediated colistin-resistance gene named mcr-1 has been recently described in different countries and it became a public health challenge. Of note, few studies have addressed the spread of Escherichia coli harboring the mcr-1 gene in both, community and hospital settings. A total of seven colistin-resistant E. coli carrying mcr-1, collected from 2016 to 2018, from community (n=4), healthcare-acquired infections (n=2) and colonization (n=1) were identified in three high complexity hospitals in Sao Paulo, Brazil. These colistin-resistant isolates were screened for mcr genes by PCR and all strains were submitted to Whole Genome Sequencing and the conjugation experiment. The seven strains belonged to seven distinct sequence types (ST744, ST131, ST69, ST48, ST354, ST57, ST10), and they differ regarding the resistance profiles. Transference of mcr-1 by conjugation to E. coli strain C600 was possible in five of the seven isolates. The mcr-1 gene was found in plasmid types IncX4 or IncI2. Three of the isolates have ESBL-encoding genes (blaCTX-M-2, n=2; blaCTX-M-8, n=1). We hereby report genetically distinct E. coli isolates, belonging to seven STs, harboring the mcr-1 gene, associated to community and healthcare-acquired infections, and colonization in patients from three hospitals in Sao Paulo. These findings point out for the potential spread of plasmid-mediated colistin-resistance mechanism in E. coli strains in Brazil.
MeSH term(s)	Anti-Bacterial Agents/pharmacology ; Brazil ; Colistin/pharmacology ; Delivery of Health Care ; Escherichia coli/genetics ; Escherichia coli Proteins/genetics ; Humans ; Microbial Sensitivity Tests
Chemical Substances	Anti-Bacterial Agents ; Escherichia coli Proteins ; MCR-1 protein, E coli ; Colistin (Z67X93HJG1)
Language	English
Publishing date	2021-04-23
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	128928-7
ISSN	1678-9946 ; 0036-4665
ISSN (online)	1678-9946
ISSN	0036-4665
DOI	10.1590/S1678-9946202163038
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Article: Combined resistance and aerobic training improves lung function and mechanics and fibrotic biomarkers in overweight and obese women.

Silva-Reis, Anamei / Rodrigues Brandao-Rangel, Maysa Alves / Moraes-Ferreira, Renilson / Gonçalves-Alves, Thiago Gibson / Souza-Palmeira, Victor Hugo / Aquino-Santos, Helida Cristina / Bachi, Andre Luis Lacerda / de Oliveira, Luis Vicente Franco / Lopes-Martins, Rodrigo Álvaro Brandão / Oliveira-Silva, Iranse / Albertini, Regiane / Frison, Claudio Ricardo / Vieira, Rodolfo P

Frontiers in physiology

2022 Volume 13, Page(s) 946402

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2022-09-07
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564217-0
ISSN	1664-042X
ISSN	1664-042X
DOI	10.3389/fphys.2022.946402
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Article: Evidence of substantial recombination among Trypanosoma cruzi II strains from Minas Gerais

Baptista, Rodrigo de Paula / Daniella Alchaar DâÃvila / Marcela Segatto / Ãtalo Faria do Valle / GlÃ³ria Regina Franco / Helder Magno Silva Valadares / Eliane Dias Gontijo / LÃºcia Maria da Cunha GalvÃ£o / SÃ©rgio Danilo Junho Pena / Egler Chiari / Carlos Renato Machado / AndrÃ©a Mara Macedo

Infection, Genetics and Evolution. 2014 Mar., v. 22

2014

Abstract: Due to the scarcity of evidence of sexuality in Trypanosoma cruzi, the causative agent of Chagas disease, it has been general accepted that the parasite reproduction is essentially clonal with infrequent genetic recombination. This assumption is mainly ... ...

Abstract	Due to the scarcity of evidence of sexuality in Trypanosoma cruzi, the causative agent of Chagas disease, it has been general accepted that the parasite reproduction is essentially clonal with infrequent genetic recombination. This assumption is mainly supported by indirect evidence, such as HardyâWeinberg imbalances, linkage disequilibrium and a strong correlation between independent sets of genetic markers of T. cruzi populations. However, because the analyzed populations are usually isolated from different geographic regions, the possibility of population substructuring as generating these genetic marker imbalances cannot be eliminated. To investigate this possibility, we firstly compared the allele frequencies and haplotype networks using seven different polymorphic loci (two from mitochondrial and five from different nuclear chromosomes) in two groups of TcII strains: one including isolates obtained from different regions in Latin America and the other including isolates obtained only from patients of the Minas Gerais State in Brazil. Our hypothesis was that if the population structure is essentially clonal, HardyâWeinberg disequilibrium and a sharp association between the clusters generated by analyzing independent markers should be observed in both strain groups, independent of the geographic origin of the samples. The results demonstrated that the number of microsatellite loci in linkage disequilibrium decreased from 4 to 1 when only strains from Minas Gerais were analyzed. Moreover, we did not observed any correlation between the clusters when analyzing the nuclear and mitochondrial loci, suggesting independent inheritance of these markers among the Minas Gerais strains. Besides, using a second subset of five physically linked microsatellite loci and the Minas Gerais strains, we could also demonstrate evidence of homologous recombination roughly proportional to the relative distance among them. Taken together, our results do not support a clonal population structure for T. cruzi, particularly in TcII, which coexists in the same geographical area, suggesting that genetic exchanges among these strains may occur more frequently than initially expected.
Keywords	Chagas disease ; Trypanosoma cruzi ; clones ; gene frequency ; genetic markers ; haplotypes ; homologous recombination ; linkage disequilibrium ; loci ; microsatellite repeats ; mitochondria ; parasites ; patients ; population structure ; provenance ; reproduction ; Brazil ; Latin America
Language	English
Dates of publication	2014-03
Size	p. 183-191.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	2037068-4
ISSN	1567-1348
ISSN	1567-1348
DOI	10.1016/j.meegid.2013.11.021
Database	NAL-Catalogue (AGRICOLA)

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