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  1. Article ; Online: How Occupational Therapy Can Contribute to the Primary Care Team and Reduce Physician Burden.

    Dahl-Popolizio, Sue / Sauber, Tina M / Mookadam, Martina

    Family practice management

    2023  Volume 30, Issue 3, Page(s) 15–19

    MeSH term(s) Humans ; Occupational Therapy ; Primary Health Care
    Language English
    Publishing date 2023-05-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1226804-5
    ISSN 1531-1929 ; 1069-5648
    ISSN (online) 1531-1929
    ISSN 1069-5648
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    Zs.A 4233: Show issues Location:
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  2. Article: Potential for sodium-glucose cotransporter-2 inhibitors in the management of metabolic syndrome: A systematic review and meta-analysis.

    Olagunju, Abdulbaril / Yamani, Naser / Kenny, Dorothy / Mookadam, Martina / Mookadam, Farouk / Unzek, Samuel

    World journal of cardiology

    2022  Volume 14, Issue 11, Page(s) 599–616

    Abstract: Background: Landmark trials have established the benefits of sodium-glucose cotransporter-2 inhibitors (SGLT2-Is) in cardiovascular disease including heart failure with reduced and preserved ejection fraction and renal diseases regardless of the ... ...

    Abstract Background: Landmark trials have established the benefits of sodium-glucose cotransporter-2 inhibitors (SGLT2-Is) in cardiovascular disease including heart failure with reduced and preserved ejection fraction and renal diseases regardless of the presence of diabetes mellitus. However, studies evaluating the role of SGLT2-Is in metabolic syndrome (MetS) are limited.
    Aim: This study primarily aimed to evaluate the impact of SGLT2-Is on the components of MetS.
    Methods: Two independent reviewers and an experienced librarian searched Medline, Scopus and the Cochrane central from inception to December 9, 2021 to identify placebo controlled randomized controlled trials that evaluated the impact of SGLT2-Is on the components of MetS as an endpoint. Pre- and post-treatment data of each component were obtained. A meta-analysis was performed using the RevMan (version 5.3; Copenhagen: The Nordic Cochrane Center, The Cochrane Collaboration).
    Results: Treatment with SGLT2-Is resulted in a decrease in fasting plasma glucose (-18.07 mg/dL; 95%CI: -25.32 to -10.82), systolic blood pressure (-1.37 mmHg; 95%CI: -2.08 to -0.65), and waist circumference (-1.28 cm; 95%CI: -1.39 to -1.18) compared to placebo. The impact on high-density lipoprotein cholesterol was similar to placebo (0.01 mg/dL; 95%CI: -0.05 to 0.07).
    Conclusion: SGLT2-Is have a promising role in the management of MetS.
    Language English
    Publishing date 2022-11-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2573665-6
    ISSN 1949-8462
    ISSN 1949-8462
    DOI 10.4330/wjc.v14.i11.599
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Who Is Most Burdened in Health Care? An Analysis of Responses to the ICAN Discussion Aid.

    Steiger, Kyle G / Boehmer, Kasey R / Klanderman, Molly C / Mookadam, Aamena / Koneru, Sethu Sandeep / Montori, Victor M / Mookadam, Martina

    Journal of the American Board of Family Medicine : JABFM

    2023  Volume 36, Issue 2, Page(s) 277–288

    Abstract: Objective: To create a model based on patients' characteristics that can predict the number of burdens reported using the ICAN Discussion Aid, to target use of this tool to patients likeliest to benefit.: Patients and methods: Six hundred thirty-five ...

    Abstract Objective: To create a model based on patients' characteristics that can predict the number of burdens reported using the ICAN Discussion Aid, to target use of this tool to patients likeliest to benefit.
    Patients and methods: Six hundred thirty-five patients (aged ≥18 years) completed the ICAN Discussion Aid at a Scottsdale, Arizona, family medicine clinic. Patient characteristics were gathered from their health records. Regression trees with Poisson splitting criteria were used to model the data.
    Results: Our model suggests the patients with the most burdens had major depressive disorder, with twice as many overall burdens (personal plus health care burdens) than patients without depression. Patients with depression who were younger than 38 years had the highest number of personal burdens. A body mass index (BMI) of 26 or greater was associated with increased health care burden versus a BMI below 26.
    Conclusion: The number of burdens a patient will report on the ICAN Discussion Aid can be approximated based on certain patient characteristics. Adults with major depression, a BMI of 26 or greater, and younger age may have greater reported burdens on ICAN, but this finding needs to be validated in independent samples.
    MeSH term(s) Adult ; Humans ; Adolescent ; Depressive Disorder, Major/diagnosis ; Depressive Disorder, Major/therapy ; Ambulatory Care Facilities ; Delivery of Health Care
    Language English
    Publishing date 2023-03-22
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 2239939-2
    ISSN 1558-7118 ; 1557-2625
    ISSN (online) 1558-7118
    ISSN 1557-2625
    DOI 10.3122/jabfm.2022.220251R1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2626: Show issues Location:
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  4. Article ; Online: Eye Movement Desensitization and Reprocessing in a Primary Care Setting: Assessing Utility and Comparing Efficacy of Virtual Versus In-Person Methods.

    Liou, Harris / Lane, Colton / Huang, Crystal / Mookadam, Martina / Joseph, Malin / Hecker DuVal, Jennifer

    Telemedicine journal and e-health : the official journal of the American Telemedicine Association

    2022  Volume 28, Issue 9, Page(s) 1359–1366

    Abstract: Introduction: ...

    Abstract Introduction:
    MeSH term(s) Adult ; COVID-19/epidemiology ; Eye Movement Desensitization Reprocessing/methods ; Eye Movements ; Humans ; Pandemics ; Primary Health Care ; Retrospective Studies ; Stress Disorders, Post-Traumatic/psychology ; Stress Disorders, Post-Traumatic/therapy ; Treatment Outcome
    Language English
    Publishing date 2022-02-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2035659-6
    ISSN 1556-3669 ; 1530-5627
    ISSN (online) 1556-3669
    ISSN 1530-5627
    DOI 10.1089/tmj.2021.0454
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4576: Show issues Location:
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  5. Article ; Online: Hypertension treatment in the elderly: a SPRINT to the finish.

    Parsons, Christine / Mookadam, Farouk / Mookadam, Martina

    Future cardiology

    2017  Volume 13, Issue 2, Page(s) 99–102

    MeSH term(s) Aged ; Antihypertensive Agents/therapeutic use ; Blood Pressure/drug effects ; Humans ; Hypertension/complications ; Hypertension/drug therapy ; Hypertension/physiopathology ; Stroke/etiology ; Stroke/prevention & control
    Chemical Substances Antihypertensive Agents
    Language English
    Publishing date 2017-02-10
    Publishing country England
    Document type Editorial
    ZDB-ID 2274267-0
    ISSN 1744-8298 ; 1479-6678
    ISSN (online) 1744-8298
    ISSN 1479-6678
    DOI 10.2217/fca-2016-0078
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6836: Show issues Location:
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  6. Article ; Online: The effect of obstructive sleep apnea treatment on cardiovascular outcomes.

    Parsons, Christine / Mookadam, Farouk / Mookadam, Martina

    Future cardiology

    2016  Volume 13, Issue 1, Page(s) 5–8

    MeSH term(s) Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/therapy ; Comorbidity ; Continuous Positive Airway Pressure/methods ; Humans ; Incidence ; Polysomnography/methods ; Prognosis ; Randomized Controlled Trials as Topic ; Risk Assessment ; Severity of Illness Index ; Sleep Apnea, Obstructive/diagnosis ; Sleep Apnea, Obstructive/epidemiology ; Sleep Apnea, Obstructive/therapy ; Treatment Outcome
    Language English
    Publishing date 2016-12-19
    Publishing country England
    Document type Editorial ; Review
    ZDB-ID 2274267-0
    ISSN 1744-8298 ; 1479-6678
    ISSN (online) 1744-8298
    ISSN 1479-6678
    DOI 10.2217/fca-2016-0069
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6836: Show issues Location:
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  7. Article ; Online: The current literature regarding the cardiovascular effects of electronic cigarettes.

    Nelluri, Bhargava / Murphy, Katie / Mookadam, Farouk / Mookadam, Martina

    Future cardiology

    2016  Volume 12, Issue 2, Page(s) 167–179

    Abstract: Smoking is the leading cause of preventable morbidity and mortality globally. Electronic cigarettes are marketed both as nicotine substitutes and recreational devices. The popularity of electronic cigarettes has superseded other forms of nicotine ... ...

    Abstract Smoking is the leading cause of preventable morbidity and mortality globally. Electronic cigarettes are marketed both as nicotine substitutes and recreational devices. The popularity of electronic cigarettes has superseded other forms of nicotine replacement therapy. They are also popular in 'never smokers'. This review summarizes the available data regarding the cardiovascular effects of electronic cigarettes. The existing literature is limited and short term with a lack of high-quality studies and adequate follow-up. The available literature suggests that electronic cigarettes have sympathomimetic effects related to nicotine exposure, however, electronic cigarettes also contain other chemicals that require further investigation. Sparse data suggest vascular injury may be another concern. Further research is needed before broad recommendations can be made.
    MeSH term(s) Cardiovascular Diseases/etiology ; Cardiovascular Diseases/physiopathology ; Electronic Nicotine Delivery Systems/adverse effects ; Humans ; Nicotine/adverse effects ; Smoking/adverse effects ; Smoking/physiopathology
    Chemical Substances Nicotine (6M3C89ZY6R)
    Language English
    Publishing date 2016-03
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2274267-0
    ISSN 1744-8298 ; 1479-6678
    ISSN (online) 1744-8298
    ISSN 1479-6678
    DOI 10.2217/fca.15.83
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Exercise training, sleep and the heart.

    Aiello, Kenneth D / Mookadam, Farouk / Mookadam, Martina

    Future cardiology

    2015  Volume 11, Issue 5, Page(s) 507–509

    MeSH term(s) Exercise/physiology ; Exercise Therapy/methods ; Global Health ; Heart Diseases/etiology ; Heart Diseases/physiopathology ; Heart Diseases/prevention & control ; Humans ; Life Style ; Morbidity/trends ; Sleep/physiology ; Sleep Apnea, Obstructive/complications ; Sleep Apnea, Obstructive/epidemiology ; Sleep Apnea, Obstructive/rehabilitation ; Survival Rate/trends
    Language English
    Publishing date 2015-09
    Publishing country England
    Document type Editorial
    ZDB-ID 2274267-0
    ISSN 1744-8298 ; 1479-6678
    ISSN (online) 1744-8298
    ISSN 1479-6678
    DOI 10.2217/fca.15.30
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6836: Show issues Location:
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  9. Article ; Online: The efficacy of continuous positive airway pressure therapy in reducing cardiovascular events in obstructive sleep apnea: a systematic review.

    Parsons, Christine / Allen, Sorcha / Parish, James / Mookadam, Farouk / Mookadam, Martina

    Future cardiology

    2017  Volume 13, Issue 4, Page(s) 397–412

    Abstract: Prospective studies show an association between obstructive sleep apnea and cardiovascular disease. Continuous positive airway pressure (CPAP) is the treatment of choice and effectively reduces subjective sleepiness and apneic and hypopneic events. ... ...

    Abstract Prospective studies show an association between obstructive sleep apnea and cardiovascular disease. Continuous positive airway pressure (CPAP) is the treatment of choice and effectively reduces subjective sleepiness and apneic and hypopneic events. However, randomized trials have not shown a reduction in cardiovascular outcomes with CPAP therapy. We review the past 10 years of randomized trial evidence regarding the therapeutic efficacy of CPAP on cardiovascular outcomes and mortality in adults with obstructive sleep apnea. The majority of studies found no significant improvement in cardiovascular outcomes with CPAP, although many noted nonsignificant benefits. Adjusted analysis in several trials showed significant cardiovascular benefit in those patients with higher CPAP compliance. Existing trials may lack sufficient follow-up and CPAP compliance, among other limitations.
    Language English
    Publishing date 2017-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2274267-0
    ISSN 1744-8298 ; 1479-6678
    ISSN (online) 1744-8298
    ISSN 1479-6678
    DOI 10.2217/fca-2017-0004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Novel Anticoagulants in Atrial Fibrillation: A Primer for the Primary Physician.

    Mookadam, Martina / Shamoun, Fadi E / Mookadam, Farouk

    Journal of the American Board of Family Medicine : JABFM

    2015  Volume 28, Issue 4, Page(s) 510–522

    Abstract: Atrial fibrillation is a common arrhythmia encountered in clinical practice. The prevalence increases with age. A devastating complication of atrial fibrillation is cardioembolic stroke with central nervous system sequelae. Based on stroke risk scores ( ... ...

    Abstract Atrial fibrillation is a common arrhythmia encountered in clinical practice. The prevalence increases with age. A devastating complication of atrial fibrillation is cardioembolic stroke with central nervous system sequelae. Based on stroke risk scores (CHADS and CHA2DS2VASc) and bleeding risk (HAS-BLED), the optimal use of anticoagulation in atrial fibrillation is feasible. Warfarin is a proven medication for this specific indication but requires frequent monitoring and dose adjustments, and it has multiple food, drug, and disease-state interactions. In addition, management of anticoagulation during the perioperative period may be challenging. In this regard, novel oral anticoagulants (NOACs) have shown promise in the shift toward the "ideal" anticoagulant therapy, in that fixed dosing is the norm, drug interactions are few, food interactions are absent, onset is fairly immediate and offset predictable, and, in the majority of patients, therapeutic monitoring is not required. This article provides a review of recent published trials of the use of NOACs in atrial fibrillation. Practical points on indications, contraindications, mechanism of action, interactions, and perioperative management tips are discussed with a view toward the safe and effective use of these new medications. When patients are transitioned between different anticoagulant medications, the risks of thrombosis and bleeding need to be considered. When switching from warfarin to a NOAC, the NOAC can be started once the international normalized ratio is ≤2.0.
    MeSH term(s) Anticoagulants/therapeutic use ; Antithrombins/therapeutic use ; Atrial Fibrillation/complications ; Atrial Fibrillation/drug therapy ; Dabigatran/therapeutic use ; Factor Xa Inhibitors/therapeutic use ; Humans ; Primary Health Care ; Pyrazoles/therapeutic use ; Pyridones/therapeutic use ; Rivaroxaban/therapeutic use ; Stroke/etiology ; Stroke/prevention & control ; Warfarin/therapeutic use
    Chemical Substances Anticoagulants ; Antithrombins ; Factor Xa Inhibitors ; Pyrazoles ; Pyridones ; apixaban (3Z9Y7UWC1J) ; Warfarin (5Q7ZVV76EI) ; Rivaroxaban (9NDF7JZ4M3) ; Dabigatran (I0VM4M70GC)
    Language English
    Publishing date 2015-07
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2239939-2
    ISSN 1558-7118 ; 1557-2625
    ISSN (online) 1558-7118
    ISSN 1557-2625
    DOI 10.3122/jabfm.2015.04.140297
    Database MEDical Literature Analysis and Retrieval System OnLINE

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