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  1. Book: Atlas of endocarditis

    Sinagra, Gianfranco / Bussani, Rossana / Cannatà, Antonio

    a clinical and pathological approach

    2016  

    Author's details editors Gianfranco Sinagra, Rossana Bussani, Antonio Cannatà
    Subject code 616
    Language English
    Size xii, 146 Seiten, Illustrationen, 25 cm
    Edition First Edition
    Publisher Il Pensiero Scientifico Editore
    Publishing place Roma
    Publishing country Italy
    Document type Book
    Note Collected essays. - Bound. - Includes bibliographical references
    HBZ-ID HT019140663
    ISBN 978-88-490-0566-0 ; 88-490-0566-0
    Database Catalogue ZB MED Medicine, Health

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  2. Article: Pheochromocytoma-Induced Tako-Tsubo Syndrome: An Uncommon Presentation.

    Artusi, Nicola / Bussani, Rossana / Cominotto, Franco

    The Journal of emergency medicine

    2022  Volume 63, Issue 1, Page(s) e1–e6

    Abstract: Background: A pheochromocytoma-induced tako-tsubo syndrome is a life-threatening complication of the rare endocrinological disease. The association between the two syndromes is known, though seldom reported in literature, but the categorization is still ...

    Abstract Background: A pheochromocytoma-induced tako-tsubo syndrome is a life-threatening complication of the rare endocrinological disease. The association between the two syndromes is known, though seldom reported in literature, but the categorization is still debated.
    Case report: In this article, we provide two examples of clinical presentation of this rare condition, its diagnosis using point-of-care ultrasound, its management in the emergency department, and finally, a literature review. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: In case of a tako-tsubo syndrome-like myocardial dysfunction in a patient with unknown medical history, or recorded hypertensive or tachycardic peaks, a point-of-care ultrasound scan extended to the kidneys could help evaluate for a reversible underlying trigger cause such as pheochromocytoma.
    MeSH term(s) Adrenal Gland Neoplasms/complications ; Adrenal Gland Neoplasms/diagnosis ; Electrocardiography ; Emergency Service, Hospital ; Humans ; Pheochromocytoma/complications ; Pheochromocytoma/diagnosis ; Syndrome ; Takotsubo Cardiomyopathy/diagnosis ; Takotsubo Cardiomyopathy/etiology
    Language English
    Publishing date 2022-08-06
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 605559-x
    ISSN 0736-4679
    ISSN 0736-4679
    DOI 10.1016/j.jemermed.2022.04.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Diffuse aspergillosis in a patient with SARS-CoV-2 pneumonia.

    Berlot, Giorgio / Tomasini, Ariella / Bussani, Rossana

    Intensive care medicine

    2021  Volume 48, Issue 5, Page(s) 609–610

    MeSH term(s) Aspergillosis/complications ; Aspergillosis/drug therapy ; COVID-19/complications ; Humans ; Invasive Pulmonary Aspergillosis ; Pneumonia ; SARS-CoV-2
    Language English
    Publishing date 2021-11-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-021-06585-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Filamin C (FLNC) truncating mutation in a fatal arrhythmogenic left ventricular cardiomyopathy (ALVC).

    Simonit, Francesco / Da Broi, Ugo / D'Elia, Angela Valentina / Fabbro, Dora / Mio, Catia / Bussani, Rossana / Pinamonti, Maurizio / Desinan, Lorenzo

    Legal medicine (Tokyo, Japan)

    2024  Volume 69, Page(s) 102438

    Abstract: Forensic pathologists are frequently asked to investigate cases of sudden death (SD), and identifying the cause of death can be of particular importance, especially where it may be necessary to perform family screening among the relatives of the victim. ... ...

    Abstract Forensic pathologists are frequently asked to investigate cases of sudden death (SD), and identifying the cause of death can be of particular importance, especially where it may be necessary to perform family screening among the relatives of the victim. A multidisciplinary approach inclusive of genetic analysis is therefore strongly recommended. According to forensic practice, arrhythmogenic cardiomyopathy (ACM) is a well-known cause of SD. However, cases of SD caused by a left ventricular pattern of ACM diagnosed at autopsy are rarely reported in the literature. We present the case of an apparently healthy, 37-year-old male found dead at his home. At autopsy, multiple foci of epicardial and mid-wall fibrous and fibro-adipose tissue were observed within the left ventricle and, to a lesser extent, within the interventricular septum. Toxicology was negative, whereas a filamin C truncating mutation was detected through genetic analysis. To our knowledge, this is the first instance of arrhythmogenic left ventricular cardiomyopathy being diagnosed at autopsy.
    Language English
    Publishing date 2024-03-26
    Publishing country Ireland
    Document type Case Reports
    ZDB-ID 2019555-2
    ISSN 1873-4162 ; 1344-6223
    ISSN (online) 1873-4162
    ISSN 1344-6223
    DOI 10.1016/j.legalmed.2024.102438
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The curious case of a massive right heart thrombosis: a case report.

    Artico, Jessica / Belgrano, Manuel / Bussani, Rossana / Sinagra, Gianfranco

    European heart journal. Case reports

    2021  Volume 5, Issue 7, Page(s) ytab156

    Abstract: Background: Intraventricular masses are a relatively rare condition ranging from asymptomatic to potentially life-threatening situations.: Case summary: Herein, we report a case of a 49-year-old woman under investigation for a massive right ... ...

    Abstract Background: Intraventricular masses are a relatively rare condition ranging from asymptomatic to potentially life-threatening situations.
    Case summary: Herein, we report a case of a 49-year-old woman under investigation for a massive right ventricular (RV) mass who underwent complete investigation for possible differential diagnosis, in the suspect of RV tumour. Multimodality imaging with cardiac computed tomography and magnetic resonance imaging showed the presence of a massive thrombus partially obliterating the right ventricle. Surgical removal of the mass showed a large area of stratified thrombosis with an underlying area of endocardial fibrosis. The patient has been then discharged in good clinical condition and with lifetime oral anticoagulation.
    Discussion: Massive RV thrombosis is a rare yet potentially fatal condition. Invasive management is preferable and lifetime anticoagulation is required to reduce possible downstream thrombotic complications.
    Language English
    Publishing date 2021-07-24
    Publishing country England
    Document type Case Reports
    ISSN 2514-2119
    ISSN (online) 2514-2119
    DOI 10.1093/ehjcr/ytab156
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Hidden left ventricular sarcoma manifesting itself with cardiogenic shock.

    Negri, Francesco / Burelli, Massimo / Bussani, Rossana / Silvestri, Furio / Imazio, Massimo / Sinagra, Gianfranco

    Journal of cardiac surgery

    2022  Volume 37, Issue 10, Page(s) 3389–3392

    Abstract: Cardiac sarcomas are rare and aggressive tumors that could have a multiorgan involvement and unfavorable prognosis. We present an extremely rare situation of cardiac sarcoma in a fragile elderly patient with a dramatic presentation of cardiogenic shock. ...

    Abstract Cardiac sarcomas are rare and aggressive tumors that could have a multiorgan involvement and unfavorable prognosis. We present an extremely rare situation of cardiac sarcoma in a fragile elderly patient with a dramatic presentation of cardiogenic shock.
    MeSH term(s) Aged ; Heart Ventricles/pathology ; Humans ; Myocardial Infarction/pathology ; Prognosis ; Sarcoma/complications ; Sarcoma/diagnosis ; Sarcoma/surgery ; Shock, Cardiogenic/etiology
    Language English
    Publishing date 2022-07-21
    Publishing country United States
    Document type Case Reports
    ZDB-ID 639059-6
    ISSN 1540-8191 ; 0886-0440
    ISSN (online) 1540-8191
    ISSN 0886-0440
    DOI 10.1111/jocs.16789
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: In response to "On challenges of disproving inferiority of tumour bed margins".

    Tirelli, Giancarlo / Bussani, Rossana / Boscolo Nata, Francesca

    Oral diseases

    2019  Volume 25, Issue 8, Page(s) 2042–2043

    MeSH term(s) Frozen Sections ; Humans ; Margins of Excision ; Mouth Neoplasms ; Surgery, Oral
    Language English
    Publishing date 2019-07-25
    Publishing country Denmark
    Document type Letter ; Comment
    ZDB-ID 1290529-x
    ISSN 1601-0825 ; 1354-523X
    ISSN (online) 1601-0825
    ISSN 1354-523X
    DOI 10.1111/odi.13164
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Cardiac Vascular Hamartoma: Adult Diagnosis and Cardiac Reconstruction.

    Franzese, Ilaria / Gripshi, Florida / Fiocco, Alessandro / Rauber, Elisabetta / Ruggiero, Danilo / Bussani, Rossana / Mazzaro, Enzo

    The Annals of thoracic surgery

    2022  Volume 115, Issue 3, Page(s) e67–e69

    Abstract: Cardiac hamartoma is a rare benign tumor of the heart, and the vascular type is an extremely rare histologic diagnosis. A small number of cases have previously been described in childhood. We report the case of a 63-year-old woman with an incidentally ... ...

    Abstract Cardiac hamartoma is a rare benign tumor of the heart, and the vascular type is an extremely rare histologic diagnosis. A small number of cases have previously been described in childhood. We report the case of a 63-year-old woman with an incidentally detected cardiac mass that was finally diagnosed as vascular hamartoma. Approval for publication was obtained from the patient.
    MeSH term(s) Female ; Humans ; Adult ; Middle Aged ; Heart ; Tomography, X-Ray Computed ; Hamartoma/diagnosis ; Plastic Surgery Procedures ; Thorax
    Language English
    Publishing date 2022-03-31
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2022.03.042
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Endomyocardial biopsy in the clinical context: current indications and challenging scenarios.

    Porcari, Aldostefano / Baggio, Chiara / Fabris, Enrico / Merlo, Marco / Bussani, Rossana / Perkan, Andrea / Sinagra, Gianfranco

    Heart failure reviews

    2022  Volume 28, Issue 1, Page(s) 123–135

    Abstract: Endomyocardial biopsy (EMB) is an invasive procedure originally developed for the monitoring of heart transplant rejection. Over the year, this procedure has gained a fundamental complementary role in the diagnostic work-up of several cardiac disorders, ... ...

    Abstract Endomyocardial biopsy (EMB) is an invasive procedure originally developed for the monitoring of heart transplant rejection. Over the year, this procedure has gained a fundamental complementary role in the diagnostic work-up of several cardiac disorders, including cardiomyopathies, myocarditis, drug-related cardiotoxicity, amyloidosis, other infiltrative and storage disorders, and cardiac tumours. Major advances in EMB equipment and techniques for histological analysis have significantly improved diagnostic accuracy of EMB. In recent years, advanced imaging modalities such as echocardiography with three-dimensional and myocardial strain analysis, cardiac magnetic resonance and bone scintigraphy have transformed the non-invasive approach to diagnosis and prognostic stratification of several cardiac diseases. Therefore, it emerges the need to re-define the current role of EMB for diagnostic work-up and management of cardiovascular diseases. The aim of this review is to summarize current knowledge on EMB in light of the most recent evidences and to discuss current indications, including challenging scenarios encountered in clinical practice.
    MeSH term(s) Humans ; Heart ; Myocardium/pathology ; Cardiomyopathies/diagnosis ; Myocarditis/pathology ; Heart Diseases/pathology ; Biopsy/methods
    Language English
    Publishing date 2022-05-14
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1336499-6
    ISSN 1573-7322 ; 1382-4147
    ISSN (online) 1573-7322
    ISSN 1382-4147
    DOI 10.1007/s10741-022-10247-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A case report of isolated cardiac light chain amyloidosis without clinically overt heart failure: an under-recognized presentation.

    Nuzzi, Vincenzo / Porcari, Aldostefano / Gigli, Marta / Zaja, Francesco / Dore, Franca / Bussani, Rossana / Sinagra, Gianfranco / Merlo, Marco

    European heart journal. Case reports

    2023  Volume 7, Issue 3, Page(s) ytad072

    Abstract: Background: Cardiac involvement in amyloid light-chain (AL) amyloidosis usually represents a brick in the wall of a multi-system disease. The presence of cardiac deposition of free light chains (FLCs) is the main determinant of survival. Isolated ... ...

    Abstract Background: Cardiac involvement in amyloid light-chain (AL) amyloidosis usually represents a brick in the wall of a multi-system disease. The presence of cardiac deposition of free light chains (FLCs) is the main determinant of survival. Isolated cardiac AL is an uncommon scenario characterized by a challenging diagnostic and therapeutic workup.
    Case summary: A 57-year-old asymptomatic man was presented for an incidental finding of myocardial necrosis at the electrocardiogram (ECG) performed for newly diagnosed arterial hypertension. Alongside signs of previous myocardial infarction, transthoracic echocardiography showed a severely increased left ventricular (LV) wall thickness not consistent with ECG voltages, segmental akinaesia with normal LV systolic function with 'apical sparing' pattern. Laboratory assessment showed an unexpectedly high level of natriuretic peptide and persistently abnormal troponin in the absence of symptoms or signs of heart failure or ongoing ischaemia. Coronary angiogram confirmed the coronary artery disease. Before revascularization, a complete diagnostic workup was carried. Serum electrophoresis detected a monoclonal gammopathy that was further investigated by serum immunofixation, revealing high lambda FLCs concentration. Fat pad, bone marrow, and salivary glands biopsies resulted negative for amyloid deposition. Finally, endomyocardial biopsy was consistent with AL amyloidosis. Urgent percutaneous revascularization was performed, and the patients was timely started on chemotherapy.
    Discussion: The diagnosis of isolated cardiac AL amyloidosis is challenging and carries important therapeutic implications. As the short-term prognosis might be severely compromised, an accurate diagnostic flowchart has to be systematically pursued to obtain a precise diagnosis and address the optimal, tailored management.
    Language English
    Publishing date 2023-02-13
    Publishing country England
    Document type Case Reports
    ISSN 2514-2119
    ISSN (online) 2514-2119
    DOI 10.1093/ehjcr/ytad072
    Database MEDical Literature Analysis and Retrieval System OnLINE

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