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  1. Article ; Online: Evidence, default videolaryngoscopy and which mode of laryngoscopy would your patient choose?

    Cook, T M

    Anaesthesia

    2023  Volume 78, Issue 6, Page(s) 791–792

    MeSH term(s) Humans ; Laryngoscopy ; Laryngoscopes ; Intubation, Intratracheal ; Patients ; Video Recording
    Language English
    Publishing date 2023-03-28
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 80033-8
    ISSN 1365-2044 ; 0003-2409
    ISSN (online) 1365-2044
    ISSN 0003-2409
    DOI 10.1111/anae.16004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Harm during airway management by anaesthetists: its absence in randomised controlled trials does not mean it does not exist.

    Hansel, J / Cook, T M

    Anaesthesia

    2024  Volume 79, Issue 4, Page(s) 444–445

    MeSH term(s) Humans ; Airway Management/adverse effects ; Anesthetists ; Intubation, Intratracheal/adverse effects ; Randomized Controlled Trials as Topic
    Language English
    Publishing date 2024-02-02
    Publishing country England
    Document type Letter
    ZDB-ID 80033-8
    ISSN 1365-2044 ; 0003-2409
    ISSN (online) 1365-2044
    ISSN 0003-2409
    DOI 10.1111/anae.16245
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Surgery soon after COVID-19: transparent big data have value but careful interpretation is still required.

    Cook, T M / Lawton, T

    Anaesthesia

    2023  Volume 78, Issue 6, Page(s) 671–676

    MeSH term(s) Humans ; COVID-19 ; Big Data ; SARS-CoV-2 ; Elective Surgical Procedures
    Language English
    Publishing date 2023-04-24
    Publishing country England
    Document type Editorial
    ZDB-ID 80033-8
    ISSN 1365-2044 ; 0003-2409
    ISSN (online) 1365-2044
    ISSN 0003-2409
    DOI 10.1111/anae.16031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: In situ gelling drug delivery systems for topical drug delivery.

    Kolawole, Oluwadamilola M / Cook, Michael T

    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

    2023  Volume 184, Page(s) 36–49

    Abstract: In situ gelling formulations are drug delivery systems which typically exist in a liquid form at room temperature and change into gel state after application to the body in response to various stimuli such as changes in temperature, pH and ionic ... ...

    Abstract In situ gelling formulations are drug delivery systems which typically exist in a liquid form at room temperature and change into gel state after application to the body in response to various stimuli such as changes in temperature, pH and ionic composition. Their biomedical application can further be improved by incorporating drug nanoparticles into in situ gelling systems in order to prolong drug release, reduce dosing frequency and improve therapeutic outcomes of patients, developing highly functional but challenging dosage forms. The composition of in situ gelling formulations influence factors relating to performance such as their syringeability, rheology, drug release profile and drug bioavailability at target sites, amongst other factors. The inclusion of mucoadhesive polymeric constituents into in situ gelling formulations has also been explored to ensure that the therapeutic agents are retained at target site for extended period of time. This review article will discuss traditional techniques (water bath-based vial inversion and viscometry) as well as advanced methodology (rheometry, differential scanning calorimetry, Small Angle Neutron Scattering, Small Angle X-ray Scattering, etc.) for evaluating in situ gel forming systems for topical drug delivery. The clinical properties of in situ gelling systems that have been studied for potential biomedical applications over the last ten years will be reviewed to highlight current knowledge in the performance of these systems. Formulation issues that have slowed the translation of some promising drug formulations from the research laboratory to the clinic will also be detailed.
    MeSH term(s) Humans ; Drug Delivery Systems/methods ; Gels/chemistry ; Drug Liberation ; Biological Availability
    Chemical Substances Gels
    Language English
    Publishing date 2023-01-13
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1065368-5
    ISSN 1873-3441 ; 0939-6411
    ISSN (online) 1873-3441
    ISSN 0939-6411
    DOI 10.1016/j.ejpb.2023.01.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Personal protective equipment during the COVID-19 pandemic: a reply.

    Cook, T M

    Anaesthesia

    2020  Volume 75, Issue 8, Page(s) 1121–1122

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Pandemics ; Personal Protective Equipment ; Pneumonia, Viral/epidemiology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-06-04
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 80033-8
    ISSN 1365-2044 ; 0003-2409
    ISSN (online) 1365-2044
    ISSN 0003-2409
    DOI 10.1111/anae.15158
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Personal protective equipment and concerns over airborne transmission of COVID-19: a reply.

    Cook, T M

    Anaesthesia

    2020  Volume 75, Issue 8, Page(s) 1117–1118

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Pandemics ; Personal Protective Equipment ; Pneumonia, Viral/epidemiology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-06-11
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 80033-8
    ISSN 1365-2044 ; 0003-2409
    ISSN (online) 1365-2044
    ISSN 0003-2409
    DOI 10.1111/anae.15143
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The importance of hypertension as a risk factor for severe illness and mortality in COVID-19.

    Cook, T M

    Anaesthesia

    2020  Volume 75, Issue 7, Page(s) 976–977

    MeSH term(s) Betacoronavirus ; COVID-19 ; China ; Coronavirus ; Coronavirus Infections ; Humans ; Hypertension ; Pandemics ; Pneumonia, Viral ; Risk Factors ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-09
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 80033-8
    ISSN 1365-2044 ; 0003-2409
    ISSN (online) 1365-2044
    ISSN 0003-2409
    DOI 10.1111/anae.15103
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Risk to health from COVID-19 for anaesthetists and intensivists - a narrative review.

    Cook, T M

    Anaesthesia

    2020  Volume 75, Issue 11, Page(s) 1494–1508

    Abstract: Healthcare workers are at an increased risk of infection, harm and death from COVID-19. Close and prolonged exposure to individuals infectious with SARS-CoV-2 leads to infection. A person's individual characteristics (age, sex, ethnicity and ... ...

    Abstract Healthcare workers are at an increased risk of infection, harm and death from COVID-19. Close and prolonged exposure to individuals infectious with SARS-CoV-2 leads to infection. A person's individual characteristics (age, sex, ethnicity and comorbidities) then influence the subsequent risk of COVID-19 leading to hospitalisation, critical care admission or death. While relative risk is often reported as a measure of individual danger, absolute risk is more important and dynamic, particularly in the healthcare setting. Individual risk interacts with exposure and environmental risk-factors, and the extent of mitigation to determine overall risk. Hospitals are a unique environment in which there is a significantly increased risk of infection for all healthcare workers. Anaesthetists and intensivists particularly are at high risk of exposure to SARS-CoV-2 infected patients due to their working environments and exposure to certain patient groups. However, the available evidence suggests that the risk for this group of individuals is not currently increased. This review examines factors associated with increased risk of infection with SARS-CoV-2, increasing severity of COVID-19 and death. A risk tool is proposed that includes personal, environmental and mitigating factors, and enables an individualised dynamic 'point-of-time' risk assessment.
    MeSH term(s) Adult ; Aged ; Anesthetists ; Betacoronavirus ; COVID-19 ; Comorbidity ; Coronavirus Infections/ethnology ; Coronavirus Infections/etiology ; Coronavirus Infections/mortality ; Coronavirus Infections/transmission ; Female ; Health Personnel ; Humans ; Intensive Care Units ; Male ; Middle Aged ; Occupational Exposure/adverse effects ; Pandemics ; Pneumonia, Viral/ethnology ; Pneumonia, Viral/etiology ; Pneumonia, Viral/mortality ; Pneumonia, Viral/transmission ; Risk Assessment ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-08-11
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 80033-8
    ISSN 1365-2044 ; 0003-2409
    ISSN (online) 1365-2044
    ISSN 0003-2409
    DOI 10.1111/anae.15220
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Personal protective equipment during the coronavirus disease (COVID) 2019 pandemic - a narrative review.

    Cook, T M

    Anaesthesia

    2020  Volume 75, Issue 7, Page(s) 920–927

    Abstract: Personal protective equipment has become an important and emotive subject during the current coronavirus disease 2019 epidemic. Coronavirus disease 2019 is predominantly caused by contact or droplet transmission attributed to relatively large respiratory ...

    Abstract Personal protective equipment has become an important and emotive subject during the current coronavirus disease 2019 epidemic. Coronavirus disease 2019 is predominantly caused by contact or droplet transmission attributed to relatively large respiratory particles which are subject to gravitational forces and travel only approximately 1 metre from the patient. Airborne transmission may occur if patient respiratory activity or medical procedures generate respiratory aerosols. These aerosols contain particles that may travel much longer distances and remain airborne longer, but their infective potential is uncertain. Contact, droplet and airborne transmission are each relevant during airway manoeuvres in infected patients, particularly during tracheal intubation. Personal protective equipment is an important component, but only one part, of a system protecting staff and other patients from coronavirus disease 2019 cross-infection. Appropriate use significantly reduces risk of viral transmission. Personal protective equipment should logically be matched to the potential mode of viral transmission occurring during patient care - contact, droplet or airborne. Recommendations from international organisations are broadly consistent, but equipment use is not. Only airborne precautions include a fitted high-filtration mask, and this should be reserved for aerosol generating procedures. Uncertainty remains around certain details of personal protective equipment including use of hoods, mask type and the potential for re-use of equipment.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/prevention & control ; Humans ; Infection Control/methods ; Pandemics/prevention & control ; Personal Protective Equipment ; Pneumonia, Viral/prevention & control ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-04-28
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 80033-8
    ISSN 1365-2044 ; 0003-2409
    ISSN (online) 1365-2044
    ISSN 0003-2409
    DOI 10.1111/anae.15071
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Unrecognised oesophageal intubation: additional human factors and ergonomics solutions.

    Kelly, F E / Cook, T M

    Anaesthesia

    2022  Volume 77, Issue 6, Page(s) 718–719

    MeSH term(s) Ergonomics ; Esophagus ; Humans ; Intubation, Intratracheal
    Language English
    Publishing date 2022-02-16
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 80033-8
    ISSN 1365-2044 ; 0003-2409
    ISSN (online) 1365-2044
    ISSN 0003-2409
    DOI 10.1111/anae.15686
    Database MEDical Literature Analysis and Retrieval System OnLINE

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