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  1. Book: Biomedical studies on temporal bones of the first multi channel cochlear implant patient at the University of Melbourne

    Clark, Graeme

    (Cochlear implants internatioinal ; 15, Suppl. 2)

    2014  

    Title variant Biomedical studies on temporal bones of the first multi-channel cochlear implant patient at the University of Melbourne
    Author's details Graeme M. Clark
    Series title Cochlear implants internatioinal ; 15, Suppl. 2
    Cochlear implants international
    Collection Cochlear implants international
    Language English
    Size S15 S. : Ill., graph. Darst.
    Publisher Maney
    Publishing place London
    Publishing country United States
    Document type Book
    HBZ-ID HT018462261
    Database Catalogue ZB MED Medicine, Health

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  2. Book: Cochlear implants

    Clark, Graeme

    fundamentals and applications

    (Modern acoustics and signal processing)

    2003  

    Author's details Graeme Clark
    Series title Modern acoustics and signal processing
    Keywords Cochlear-Implantat
    Subject Kochlear-Implantat ; Cochlear Implant ; Cochlea-Implantat ; Cochleaimplantat ; CI
    Language English
    Size XXXVIII, 830 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT013748339
    ISBN 0-387-95583-6 ; 978-0-387-95583-4
    Database Catalogue ZB MED Medicine, Health

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  3. Book: Cochlear implantation for infants and children

    Clark, Graeme

    advances

    1997  

    Author's details ed. Graeme M. Clark
    Keywords Cochlear Implants / in infancy & childhood ; Cochlear-Implantat ; Kind
    Subject Kindheit ; Kindesalter ; Kindschaft ; Kinder ; Kochlear-Implantat ; Cochlear Implant ; Cochlea-Implantat ; Cochleaimplantat ; CI
    Language English
    Size X, 263 S. : zahlr. Ill., graph. Darst.
    Publisher Singular Publ
    Publishing place San Diego u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT008386832
    ISBN 1-56593-727-9 ; 978-1-56593-727-7
    Database Catalogue ZB MED Medicine, Health

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  4. Book ; Conference proceedings: International Cochlear Implant, Speech and Hearing Symposium

    Clark, Graeme

    Melbourne 1994

    (Annals of otology, rhinology & laryngology : Supplement ; 166)

    1995  

    Event/congress International Cochlear Implant, Speech and Hearing Symposium (1994, Melbourne)
    Author's details ed. Graeme M. Clark
    Series title Annals of otology, rhinology & laryngology : Supplement ; 166
    The annals of otology, rhinology & laryngology
    Annals of otology, rhinology & laryngology ; Supplement
    Collection The annals of otology, rhinology & laryngology
    Annals of otology, rhinology & laryngology ; Supplement
    Keywords Cochlear Implants / congresses ; Cochlear-Implantat
    Subject Kochlear-Implantat ; Cochlear Implant ; Cochlea-Implantat ; Cochleaimplantat ; CI
    Language English
    Size 468 S. : Ill., graph. Darst.
    Publisher Annals Publ
    Publishing place St. Louis, Mo
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT006799202
    Database Catalogue ZB MED Medicine, Health

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  5. Book: Cochlear prostheses

    Clark, Graeme

    1990  

    Author's details edited by Graeme M. Clark
    Keywords Cochlear Implants ; Deafness / rehabilitation
    Size VII, 264 S. : Ill., graph. Darst.
    Publisher Churchill Livingstone
    Publishing place Edinburgh u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT003670099
    ISBN 0-443-03582-2 ; 978-0-443-03582-1
    Database Catalogue ZB MED Medicine, Health

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  6. Article ; Online: The multichannel cochlear implant for severe-to-profound hearing loss.

    Clark, Graeme M

    Nature medicine

    2013  Volume 19, Issue 10, Page(s) 1236–1239

    MeSH term(s) Cochlear Implants ; Hearing Loss/surgery ; Humans
    Language English
    Publishing date 2013-10-08
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1220066-9
    ISSN 1546-170X ; 1078-8956
    ISSN (online) 1546-170X
    ISSN 1078-8956
    DOI 10.1038/nm.3340
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: A prototype lateral flow assay for detection of orthopoxviruses.

    Ulaeto, David O / Lonsdale, Steve G / Laidlaw, Stephen M / Clark, Graeme C / Horby, Peter / Carroll, Miles W

    The Lancet. Infectious diseases

    2022  Volume 22, Issue 9, Page(s) 1279–1280

    MeSH term(s) Biological Assay ; DNA, Viral ; Humans ; Orthopoxvirus ; Polymerase Chain Reaction
    Chemical Substances DNA, Viral
    Language English
    Publishing date 2022-07-04
    Publishing country United States
    Document type Letter
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(22)00440-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The multi-channel cochlear implant: multi-disciplinary development of electrical stimulation of the cochlea and the resulting clinical benefit.

    Clark, Graeme M

    Hearing research

    2015  Volume 322, Page(s) 4–13

    Abstract: This multi-disciplinary research showed sound could be coded by electrical stimulation of the cochlea and peripheral auditory nervous system. But the temporal coding of frequency as seen in the experimental animal, was inadequate for the important speech ...

    Abstract This multi-disciplinary research showed sound could be coded by electrical stimulation of the cochlea and peripheral auditory nervous system. But the temporal coding of frequency as seen in the experimental animal, was inadequate for the important speech frequencies. The data indicated the limitation was due in particular to deterministic firing of neurons and failure to reproduce the normal fine temporo-spatial pattern of neural responses seen with sound. However, the data also showed the need for the place coding of frequency, and this meant multi-electrodes inserted into the cochlea. Nevertheless, before this was evaluated on people we undertook biological safety studies to determine the effects of surgical trauma and electrical stimuli, and how to prevent infection. Then our research demonstrated place of stimulation had timbre and was perceived as vowels. This led to our discovery in 1978 of the formant-extraction speech code that first enabled severely-profoundly deaf people to understand running speech. This result in people who had hearing before becoming severely deaf was an outcome not previously considered possible. In 1985 it was the first multi-channel implant to be approved by the US Food and Drug Administration (FDA). It was also the fore runner of our advanced formant and fixed filter strategies When these codes were used from 1985 for those born deaf or deafened early in life we discovered there was a critical period when brain plasticity would allow speech perception and language to be developed near- normally, and this required in particular the acquisition of place coding. In 1990 this led to the first cochlear implant to be approved by the FDA for use in children. Finally, we achieved binaural hearing in 1989 with bilateral cochlear implants, followed by bimodal speech processing in 1990 with a hearing aid in one ear and implant in the other. The above research has been developed industrially, with for example 250,000 people worldwide receiving the Cochlear device in 2013, and as of December 2012 the NIH estimated that approximately 324,200 people worldwide had received this and other implants (NIH Publication No. 11-4798). This article is part of a Special Issue entitled <Lasker Award>.
    MeSH term(s) Acoustic Stimulation ; Animals ; Cochlear Implantation/instrumentation ; Cochlear Implants ; Comprehension ; Cooperative Behavior ; Electric Stimulation ; Humans ; Interdisciplinary Communication ; Persons With Hearing Impairments/psychology ; Persons With Hearing Impairments/rehabilitation ; Prosthesis Design ; Signal Processing, Computer-Assisted ; Speech Intelligibility ; Speech Perception
    Language English
    Publishing date 2015-04
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 282629-x
    ISSN 1878-5891 ; 0378-5955
    ISSN (online) 1878-5891
    ISSN 0378-5955
    DOI 10.1016/j.heares.2014.08.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Restoration of the senses and human communication: Sustainable Development Goals 3 and 9.

    Zoneff, Elizabeth R / Gao, Demi X / Nisbet, David R / Grayden, David B / Clark, Graeme M

    International journal of speech-language pathology

    2022  Volume 25, Issue 1, Page(s) 9–14

    Abstract: Purpose: This invited commentary addresses the importance of the senses in human communication, outlines advances achieved with cochlear implants, and new research directions to improve neural prostheses.: Result: In severely deaf people, cochlear ... ...

    Abstract Purpose: This invited commentary addresses the importance of the senses in human communication, outlines advances achieved with cochlear implants, and new research directions to improve neural prostheses.
    Result: In severely deaf people, cochlear implants restore speech understanding and enable children to achieve spoken language. Research in neural prostheses is advancing the restoration of hearing, vision, tactile senses, movement and the management of epilepsy. Bio-inspired stimulation strategies incorporating temporal and spatial characteristics of neural responses may deliver improved speech, vision and tactile perception using prostheses. To achieve stable long-term stimulation, chronic inflammation at the brain-electrode interface may be reduced using ROCK/Rho signalling pathway inhibitors and materials with brain-mimicking properties.
    Conclusion: This commentary paper addresses two Sustainable Development Goals: industry, innovation and infrastructure (SDG 9) and good health and well-being (SDG 3).
    MeSH term(s) Child ; Humans ; Sustainable Development ; Cochlear Implants ; Cochlear Implantation ; Speech
    Language English
    Publishing date 2022-12-08
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2402483-1
    ISSN 1754-9515 ; 1754-9507
    ISSN (online) 1754-9515
    ISSN 1754-9507
    DOI 10.1080/17549507.2022.2142290
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book ; Conference proceedings: International Cochlear Implant Symposium and Workshop

    Clark, Graeme

    Melbourne, 1985

    (Annals of otology, rhinology & laryngology : Supplement ; 128)

    1987  

    Institution University of Melbourne / Department of Otolaryngology
    Event/congress International Cochlear Implant Symposium and Workshop (1985, Melbourne)
    Author's details ed. Graeme M. Clark ... Organized by the Dep. of Otolaryngology ... of the Fac. of Medicine, Univ. of Melbourne
    Series title Annals of otology, rhinology & laryngology : Supplement ; 128
    The annals of otology, rhinology & laryngology
    Annals of otology, rhinology & laryngology ; Supplement
    Collection The annals of otology, rhinology & laryngology
    Annals of otology, rhinology & laryngology ; Supplement
    Keywords Cochlear Implants / congresses
    Size 152 S. : Ill., graph. Darst.
    Publisher Annals Publ. Co
    Publishing place St. Louis, Mo
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT003118012
    Database Catalogue ZB MED Medicine, Health

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