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  1. Article: Post Surgical Non-tuberculous Mycobacterium: A Case Series.

    Mhaske, Ashok N / Mhaske, Shubhangi / Harke, Sanjay / Jain, Arti / Patel, Jaswant / Mhaske, Sumedh

    Cureus

    2022  Volume 14, Issue 5, Page(s) e24701

    Abstract: Background There has been an increase in non-tuberculous mycobacteria (NTM) infection reports in humans. Surgeons are concerned about the link between them and surgical site infections. As a result, it has been challenging to determine just how common ... ...

    Abstract Background There has been an increase in non-tuberculous mycobacteria (NTM) infection reports in humans. Surgeons are concerned about the link between them and surgical site infections. As a result, it has been challenging to determine just how common this illness is. A two-year study by the authors examines the occurrence of NTM infections after different surgical procedures. Design and methods Researchers at a tertiary care hospital in central India performed this prospective study over two years. NTM was found in six of the 25 instances of post-surgical wound infections. Ziehl-Neelsen staining, Auramine O-Rhodamine fluorescence staining, Multiplex Real-Time PCR, and Genotyping were used to identify the species. Results
    Language English
    Publishing date 2022-05-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.24701
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Elective Neck Dissection Versus Therapeutic Neck Dissection in Clinically Node-Negative Early Stage Oral Cancer: A Meta-analysis of Randomized Controlled Trials.

    Kumar, Anshuman / Ghai, Suhani / Mhaske, Shubhangi / Singh, Renu

    Journal of maxillofacial and oral surgery

    2022  Volume 21, Issue 2, Page(s) 340–349

    Abstract: Introduction: Oral squamous cell carcinoma (OSCC) is characterized by a high risk of cervical lymph node metastasis; however, it is still not clear whether patients with early stage OSCC with clinical N0 neck should undergo elective neck dissection (END) ...

    Abstract Introduction: Oral squamous cell carcinoma (OSCC) is characterized by a high risk of cervical lymph node metastasis; however, it is still not clear whether patients with early stage OSCC with clinical N0 neck should undergo elective neck dissection (END) at the time of primary tumor removal, or they should undergo a conservative approach of observation (OBS), with therapeutic neck dissection at the time of lymph nodal recurrence. We conducted a meta-analysis of randomized controlled trials (RCTs) that compared these two approaches.
    Methods: PubMed and Scopus databases were searched for RCTs published in English language related to END and OBS in patients with early stage OSCC with clinical N0 neck. A meta-analysis was performed using random effects model with hazard ratio (HR) as the effect size for survival parameters and odds ratio (OR) as the effect size for lymph nodal recurrence.
    Results: A total of 7 RCTs, comprising 1250 patients were included in the meta-analysis. Results of the meta-analyses showed that as compared to OBS approach, END could significantly improve overall survival (HR 0.67; 95% CI 0.53, 0.86) and disease-free survival (HR 0.64; 95% CI 0.46, 0.89), and significantly reduce lymph nodal recurrence (OR 0.28; 95% CI 0.12, 0.66). After correcting for heterogeneity, the disease specific survival was also found to be improved by the END approach (HR 0.53; 95% CI 0.29, 0.98).
    Conclusion: The results of this meta-analysis suggest that elective neck dissection at the time of resection of the primary tumor not only leads to a reduced chance of nodal recurrence, but also confers a survival benefit in patients with clinically node-negative early stage oral cancer.
    Language English
    Publishing date 2022-01-06
    Publishing country India
    Document type Journal Article
    ZDB-ID 2502352-4
    ISSN 0974-942X ; 0972-8279
    ISSN (online) 0974-942X
    ISSN 0972-8279
    DOI 10.1007/s12663-021-01677-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Rapidly Growing Mycobacterium in Postsurgical Wounds

    Ashok Mhaske / Shubhangi Mhaske / Sanjay Harke / Arti Jain / Jaswant Patel

    Journal of Clinical and Diagnostic Research, Vol 15, Iss 12, Pp 01-

    A Systematic Review and Meta-analysis

    2021  Volume 05

    Abstract: Introduction: Rapidly Growing Mycobacteria (RGM) are extensively found in nature and is isolated as an environmental saprophyte from water sources and soil. The incidence of these opportunistic pathogens has increased in the recent years as nosocomial ... ...

    Abstract Introduction: Rapidly Growing Mycobacteria (RGM) are extensively found in nature and is isolated as an environmental saprophyte from water sources and soil. The incidence of these opportunistic pathogens has increased in the recent years as nosocomial outbreaks, with an exaggerated outcome of morbidity and resistant antibiotic intervention. Aim: To assess the occurrence of rapidly growing mycobacteria in postsurgical wounds. Materials and Methods: Literature search in PubMed, Google Scholar and Scopus of published articles in English language from March 2010 to December 2020 were anlaysed for the predetermined outcomes. Keywords used for the literature search were “atypical mycobacteria”; “non tuberculous mycobacteria”; “rapidly progressing mycobacteria”; “RGM”; “postsurgical wounds”; “surgical site infection”; “wound site”; “port hole infections”. A total of 10 studies adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were included for statistical analysis. OpenMeta-Analyst software was used. Results: A prevalence of 56.4% (95% CI: 33.0; 79.8) was noted in 592 patients evaluated postsurgically. The articles included were of fair quality when assessed on Ottawa scale. M.Chelonae, M.Abscessus, M.fortuitum and M.massiliense were the most commonly isolated organisms. Clarithromycin, Amikacin, Ciprofloxacin, Imepenem and Linezolids were administered as antibiotic intervention. Conclusion: Considering the higher prevalence of RGM infection (56.40%), every surgeon must consider the possibility of this opportunistic infection. It is vital to address this issue to eliminate the risk of severe outcome.
    Keywords antibiotics ; non tuberculous mycobacteria ; occurrence ; surgical infection ; Medicine ; R
    Language English
    Publishing date 2021-12-01T00:00:00Z
    Publisher JCDR Research and Publications Private Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Oral submucous fibrosis – An Alarmingly Increasing Youth Morbidity

    Shubhangi Mhaske / Ashok Mhaske

    Al Ameen Journal of Medical Sciences , Vol 09, Iss 01, Pp 1-

    2016  Volume 3

    Keywords Oral Submucus fibrosis ; Youth Morbidity ; gutka ; Medicine (General) ; R5-920 ; Medicine ; R
    Language English
    Publishing date 2016-01-01T00:00:00Z
    Publisher Dr.B.S.Patil
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Perspective on oral exfoliative cytology and COVID-19.

    Mhaske, Shubhangi / Yuwanati, Monal / Mhaske, Ashok / Desai, Ami / Sarode, Sachin C / Sarode, Gargi S

    Oral oncology

    2020  Volume 107, Page(s) 104858

    MeSH term(s) Asymptomatic Infections ; Betacoronavirus/isolation & purification ; Biopsy/methods ; COVID-19 ; COVID-19 Testing ; Cell Line ; Clinical Laboratory Techniques/methods ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/pathology ; Coronavirus Infections/virology ; Epithelial Cells/virology ; Humans ; Mass Screening/methods ; Mouth Mucosa/cytology ; Mouth Mucosa/pathology ; Mouth Mucosa/virology ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/pathology ; Pneumonia, Viral/virology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-06-12
    Publishing country England
    Document type Letter
    ZDB-ID 1120465-5
    ISSN 1879-0593 ; 0964-1955 ; 1368-8375
    ISSN (online) 1879-0593
    ISSN 0964-1955 ; 1368-8375
    DOI 10.1016/j.oraloncology.2020.104858
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Textbook of oral pathology

    Ghom, Anil / Mhaske, Shubhangi

    2013  

    Author's details editors, Anil Govindrao Ghom, Shubhangi Mhaske (Jedhe) ; forewords, Manisha Sanjay Tijare, Jagdish V. Tupkari
    MeSH term(s) Stomatognathic Diseases/pathology
    Language English
    Size xxiv, 1025 pages :, illustrations, portraits
    Edition Second edition.
    Document type Book
    ISBN 9789350901717 ; 9350901714
    Database Catalogue of the US National Library of Medicine (NLM)

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  8. Article: EXPRESSION OF ALPHA-SMOOTH MUSCLE ACTIN IN ODONTOGENIC CYSTS AND TUMORS.

    Ahmad, Malik Ajaz / Gupta, Anish Ashok / Mhaske, Shubhangi Ashok / Saawarn, Swati / Ashok, Sahana / Mandora, Dakshata / Jain, Megha

    Experimental oncology

    2022  Volume 44, Issue 3, Page(s) 249–253

    Abstract: Background: Odontogenic cysts and tumors exhibit different degrees of aggressiveness in their biological behavior. There has been evidence that the presence of myofibroblasts (MFs) at the invasion front promotes tumor invasion. Our study is based on the  ...

    Abstract Background: Odontogenic cysts and tumors exhibit different degrees of aggressiveness in their biological behavior. There has been evidence that the presence of myofibroblasts (MFs) at the invasion front promotes tumor invasion. Our study is based on the fact that MFs are important in the biological behavior of odontogenic cysts and tumors.
    Aim: To assess immunohistochemically expression of alpha-smooth muscle actin (α-SMA) of MFs in odontogenic cysts and tumors and correlate this expression to their biological behavior.
    Materials and methods: The archival tissues collected for 1.5 years were obtained from the Department of Oral Pathology & Microbiology, People's Dental Academy, Bhopal (India). A total of 40 cases consisting of 10 cases each of odontogenic keratocysts, radicular cysts, dentigerous cysts and ameloblastomas formed the study group. An immunohistochemical analysis of α-SMA expression and localization was carried out.
    Results: Mean MF counts were the highest in odontogenic keratocysts which was followed by ameloblastomas, entigerous cysts and radicular cysts. Weak α-SMA-expression was found in 50% of cases, moderate in 22.5% of cases, and intense - in 10% cases. MFs were arranged in the spindle, focal, or network patterns in 35; 27.5 and 20% of cases, respectively.
    Conclusion: The analysis revealed that the MFs were distinctly heterogeneous in distribution and pattern of arrangement. This provided persuasive evidence that stroma of these lesions harbor MFs as reflected by α-SMA immunopositive cells.
    MeSH term(s) Humans ; Ameloblastoma/metabolism ; Ameloblastoma/pathology ; Actins ; Immunohistochemistry ; Odontogenic Cysts/metabolism ; Odontogenic Cysts/pathology ; Odontogenic Tumors/pathology ; Radicular Cyst/metabolism ; Radicular Cyst/pathology ; Muscle, Smooth/metabolism ; Muscle, Smooth/pathology
    Chemical Substances Actins
    Language English
    Publishing date 2022-10-31
    Publishing country Ukraine
    Document type Journal Article
    ZDB-ID 2176927-8
    ISSN 1812-9269 ; 0204-3564
    ISSN 1812-9269 ; 0204-3564
    DOI 10.32471/exp-oncology.2312-8852.vol-44-no-3.18676
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Perspective on oral exfoliative cytology and COVID-19

    Mhaske, Shubhangi / Yuwanati, Monal / Mhaske, Ashok / Desai, Ami / Sarode, Sachin C. / Sarode, Gargi S.

    Oral Oncology

    2020  Volume 107, Page(s) 104858

    Keywords Cancer Research ; Oral Surgery ; Oncology ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1120465-5
    ISSN 1879-0593 ; 0964-1955 ; 1368-8375
    ISSN (online) 1879-0593
    ISSN 0964-1955 ; 1368-8375
    DOI 10.1016/j.oraloncology.2020.104858
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4869: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.A 456: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  10. Article: Congenital granular cell tumor - a rare entity.

    Yuwanati, Monal / Mhaske, Shubhangi / Mhaske, Ashok

    Journal of neonatal surgery

    2015  Volume 4, Issue 2, Page(s) 17

    Abstract: Congenital granular cell tumor is a rare benign neoplastic growth affecting the gingival mucosa of neonates. Prenatal ultrasound diagnosis has recently come to focus and in spite of several reports on immune-histochemical and other advanced marker ... ...

    Abstract Congenital granular cell tumor is a rare benign neoplastic growth affecting the gingival mucosa of neonates. Prenatal ultrasound diagnosis has recently come to focus and in spite of several reports on immune-histochemical and other advanced marker studies, the cause and origin of the lesion remains debatable till date. Review of literature on prenatal diagnosis and histopathology along with immunohistochemistry is discussed.
    Language English
    Publishing date 2015-04-01
    Publishing country Pakistan
    Document type Journal Article ; Review
    ISSN 2226-0439
    ISSN 2226-0439
    Database MEDical Literature Analysis and Retrieval System OnLINE

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