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  1. Article ; Online: Ozanimod for Ulcerative Colitis. Reply.

    Sandborn, William J / Danese, Silvio

    The New England journal of medicine

    2022  Volume 386, Issue 2, Page(s) 194–195

    MeSH term(s) Colitis, Ulcerative/drug therapy ; Humans ; Indans ; Oxadiazoles
    Chemical Substances Indans ; Oxadiazoles ; ozanimod (Z80293URPV)
    Language English
    Publishing date 2022-01-12
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2117224
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Conference proceedings: Updates from the front lines of Crohn's disease

    Sandborn, William J.

    achieving a balance between safety and efficacy ; a report of a symposium presented during Digestive Disease Week, May 20, 2008, San Diego, California

    (Gastroenterology & hepatology ; 4,7, Suppl. 14)

    2008  

    Event/congress Digestive Disease Week (2008, SanDiegoCalif.)
    Author's details faculty William J. Sandborn
    Series title Gastroenterology & hepatology ; 4,7, Suppl. 14
    Collection
    Language English
    Size 14 S. : graph. Darst.
    Publisher Gastro-Hep Comm
    Publishing place New York, NY
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT015677054
    Database Catalogue ZB MED Medicine, Health

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  3. Book: Long term approach to managing patients with mild to moderate Crohn's disease

    Sandborn, William J.

    (Gastroenterology & hepatology ; 2,4, Suppl. 3 : Clinical roundtable monograph)

    2006  

    Title variant Long-term approach to managing patients with mild to moderate Crohn's disease
    Author's details moderator William J. Sandborn
    Series title Gastroenterology & hepatology ; 2,4, Suppl. 3 : Clinical roundtable monograph
    Collection
    Language English
    Size 10 S. : Ill., graph. Darst.
    Publisher Gastro-Hep Comm
    Publishing place New York, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT015359081
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Reply.

    D'Haens, Geert R / Sandborn, William J

    Gastroenterology

    2022  

    Language English
    Publishing date 2022-09-05
    Publishing country United States
    Document type Letter
    ZDB-ID 80112-4
    ISSN 1528-0012 ; 0016-5085
    ISSN (online) 1528-0012
    ISSN 0016-5085
    DOI 10.1053/j.gastro.2022.09.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book ; Conference proceedings: The keys to IBD 2010

    Rogler, Gerhard / Sandborn, William J.

    treatment, diagnosis and pathophysiology ; Falk Symposium 172, Miami, Fla., March 2010 ; 29 tables

    (Falk Symposium ; 172)

    2010  

    Event/congress Falk Symposium (172, 2010, MiamiFla.)
    Author's details ed. G. Rogler ; W. Sandborn
    Series title Falk Symposium ; 172
    Falk symposium series
    Collection Falk symposium series
    Keywords Inflammatory Bowel Diseases
    Language English
    Size S. 387 - 567 : Ill., graph. Darst.
    Publisher Karger
    Publishing place Basel u.a.
    Publishing country Switzerland
    Document type Book ; Conference proceedings
    HBZ-ID HT016589480
    ISBN 978-3-8055-9588-9 ; 3-8055-9588-3
    Database Catalogue ZB MED Medicine, Health

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  6. Book ; Conference proceedings: The keys to IBD 2010

    Rogler, Gerhard / Sandborn, William J.

    treatment, diagnosis and pathophysiology ; Falk Symposium 172, March 26 - 27, 2010, Miami, Fla. ; 29 tables

    (Digestive diseases ; 28,3)

    2010  

    Event/congress Falk Symposium (172, 2010, MiamiFla.)
    Author's details ed. G. Rogler ; W. Sandborn
    Series title Digestive diseases ; 28,3
    Collection
    Language English
    Size S. 385 - 567 : Ill., graph. Darst.
    Publisher Karger
    Publishing place Basel u.a.
    Publishing country Switzerland
    Document type Book ; Conference proceedings
    HBZ-ID HT016541975
    ISBN 978-3-8055-9589-6 ; 9783805595902 ; 3-8055-9589-1 ; 3805595905
    Database Catalogue ZB MED Medicine, Health

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  7. Article ; Online: Advances in the Comprehensive Management of Postoperative Crohn's Disease.

    Battat, Robert / Sandborn, William J

    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

    2021  Volume 20, Issue 7, Page(s) 1436–1449

    Abstract: Patients with postoperative Crohn's disease are difficult to manage because of their risk of experiencing a more severe course, multiple symptom confounders, and poor sensitivity of symptomatic remission to rule out intestinal inflammation. In this group, ...

    Abstract Patients with postoperative Crohn's disease are difficult to manage because of their risk of experiencing a more severe course, multiple symptom confounders, and poor sensitivity of symptomatic remission to rule out intestinal inflammation. In this group, data are lacking on biologic therapeutic efficacy, and recommendations are lacking for those with multiple medication failures. Novel noninvasive testing can simultaneously exclude alternate causes of symptoms (serum C4, fecal fat, small intestinal bowel overgrowth breath testing) and assess intestinal inflammation (fecal calprotectin, endoscopic healing index). In addition, endoscopy-based disease activity assessment and management are required. Endoscopy should be performed within 6 months of surgery, and aggressive disease activity monitoring can be considered with colonoscopy every 1-2 years subsequently to ensure late recurrence is detected. Patients with multiple resections should be screened for short bowel syndrome. Predictive biomarkers are needed to guide medication selection in this high-risk population. Postoperative prophylactic biologic therapy is prudent for patients with preoperative biologic failure. However, there are no high-quality data to guide which agent should be selected. Selecting biologics with an alternative mechanism of action in those who had failed a biologic with adequate drug concentrations and selection of different agents in those with previous intolerance are reasonable. Significantly more study is required to assess the efficacy of therapies in this setting.
    MeSH term(s) Biomarkers/analysis ; Crohn Disease/diagnosis ; Crohn Disease/drug therapy ; Crohn Disease/surgery ; Endoscopy, Gastrointestinal ; Feces/chemistry ; Humans ; Inflammation ; Leukocyte L1 Antigen Complex
    Chemical Substances Biomarkers ; Leukocyte L1 Antigen Complex
    Language English
    Publishing date 2021-04-02
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 2119789-1
    ISSN 1542-7714 ; 1542-3565
    ISSN (online) 1542-7714
    ISSN 1542-3565
    DOI 10.1016/j.cgh.2021.03.048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: New Targets for Small Molecules in Inflammatory Bowel Disease.

    Sandborn, William J

    Gastroenterology & hepatology

    2016  Volume 11, Issue 5, Page(s) 338–340

    Language English
    Publishing date 2016-06-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2386402-3
    ISSN 1554-7914
    ISSN 1554-7914
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: The Present and Future of Inflammatory Bowel Disease Treatment.

    Sandborn, William J

    Gastroenterology & hepatology

    2016  Volume 12, Issue 7, Page(s) 438–441

    Language English
    Publishing date 2016-05-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2386402-3
    ISSN 1554-7914
    ISSN 1554-7914
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Defining Endpoints and Biomarkers in Inflammatory Bowel Disease: Moving the Needle Through Clinical Trial Design.

    Abreu, Maria T / Sandborn, William J

    Gastroenterology

    2020  Volume 159, Issue 6, Page(s) 2013–2018.e7

    MeSH term(s) Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Biomarkers/analysis ; Cecum/diagnostic imaging ; Cecum/drug effects ; Cecum/immunology ; Cecum/pathology ; Clinical Trials as Topic/standards ; Colitis, Ulcerative/diagnosis ; Colitis, Ulcerative/drug therapy ; Colitis, Ulcerative/immunology ; Colon/diagnostic imaging ; Colon/drug effects ; Colon/immunology ; Colon/pathology ; Colonoscopy ; Crohn Disease/diagnosis ; Crohn Disease/drug therapy ; Crohn Disease/immunology ; Drug Discovery ; Humans ; Ileum/diagnostic imaging ; Ileum/drug effects ; Ileum/immunology ; Ileum/pathology ; Research Design/standards ; Severity of Illness Index ; Treatment Outcome
    Chemical Substances Anti-Inflammatory Agents ; Biomarkers
    Language English
    Publishing date 2020-09-19
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80112-4
    ISSN 1528-0012 ; 0016-5085
    ISSN (online) 1528-0012
    ISSN 0016-5085
    DOI 10.1053/j.gastro.2020.07.064
    Database MEDical Literature Analysis and Retrieval System OnLINE

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