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  1. Book: Nathan Birnbaum

    Herrmann, Leo / Birnbaum, Nathan

    sein Werk und seine Wandlung

    (Die Jüdische Gemeinschaft ; [4])

    1914  

    Author's details von Leo Herrmann
    Series title Die Jüdische Gemeinschaft ; [4]
    Language German
    Size 31 S.
    Publisher Jüd. Verl
    Publishing place Berlin
    Document type Book
    Database Former special subject collection: coastal and deep sea fishing

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  2. Article ; Online: Mirtazapine for agitation in dementia: moving forward.

    Lanctôt, Krista L / Herrmann, Nathan

    Lancet (London, England)

    2021  Volume 398, Issue 10310, Page(s) 1462–1463

    MeSH term(s) Antidepressive Agents/therapeutic use ; Dementia/drug therapy ; Humans ; Mianserin/therapeutic use ; Mirtazapine/therapeutic use
    Chemical Substances Antidepressive Agents ; Mianserin (250PJI13LM) ; Mirtazapine (A051Q2099Q)
    Language English
    Publishing date 2021-10-04
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(21)01421-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Cholinesterase Inhibitor Discontinuation: The Buck Stops Here.

    Herrmann, Nathan

    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    2017  Volume 26, Issue 2, Page(s) 148–149

    MeSH term(s) Cholinesterase Inhibitors/administration & dosage ; Dementia/drug therapy ; Deprescriptions ; Humans
    Chemical Substances Cholinesterase Inhibitors
    Language English
    Publishing date 2017-10-31
    Publishing country England
    Document type Editorial
    ZDB-ID 1278145-9
    ISSN 1545-7214 ; 1064-7481
    ISSN (online) 1545-7214
    ISSN 1064-7481
    DOI 10.1016/j.jagp.2017.10.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Targeted Treatment of Advanced Endometrial Cancer: Focus on Pembrolizumab.

    El-Ghazzi, Nathan / Durando, Xavier / Giro, Alexia / Herrmann, Tressie

    OncoTargets and therapy

    2023  Volume 16, Page(s) 359–369

    Abstract: Endometrial cancer (EC) accounts for 2% of all new cancers. Advanced forms have a poor prognosis with barely 17% 5-year survival. The last few years improved our knowledge of EC with a new molecular classification derived from The Cancer Genome Atlas ( ... ...

    Abstract Endometrial cancer (EC) accounts for 2% of all new cancers. Advanced forms have a poor prognosis with barely 17% 5-year survival. The last few years improved our knowledge of EC with a new molecular classification derived from The Cancer Genome Atlas (TCGA). They are now divided between
    Language English
    Publishing date 2023-06-02
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2495130-4
    ISSN 1178-6930
    ISSN 1178-6930
    DOI 10.2147/OTT.S368050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Mechanical Models of Collagen Networks for Understanding Changes in the Failure Properties of Aging Skin.

    Witt, Nathan J / Woessner, Alan E / Herrmann, Jacob / Quinn, Kyle P / Sander, Edward A

    Journal of biomechanical engineering

    2024  Volume 146, Issue 7

    Abstract: Skin undergoes mechanical alterations due to changes in the composition and structure of the collagenous dermis with aging. Previous studies have conflicting findings, with both increased and decreased stiffness reported for aging skin. The underlying ... ...

    Abstract Skin undergoes mechanical alterations due to changes in the composition and structure of the collagenous dermis with aging. Previous studies have conflicting findings, with both increased and decreased stiffness reported for aging skin. The underlying structure-function relationships that drive age-related changes are complex and difficult to study individually. One potential contributor to these variations is the accumulation of nonenzymatic crosslinks within collagen fibers, which affect dermal collagen remodeling and mechanical properties. Specifically, these crosslinks make individual fibers stiffer in their plastic loading region and lead to increased fragmentation of the collagenous network. To better understand the influence of these changes, we investigated the impact of nonenzymatic crosslink changes on the dermal microstructure using discrete fiber networks representative of the dermal microstructure. Our findings suggest that stiffening the plastic region of collagen's mechanical response has minimal effects on network-level stiffness and failure stresses. Conversely, simulating fragmentation through a loss of connectivity substantially reduces network stiffness and failure stress, while increasing stretch ratios at failure.
    MeSH term(s) Skin Aging ; Stress, Mechanical ; Extracellular Matrix ; Collagen ; Skin
    Chemical Substances Collagen (9007-34-5)
    Language English
    Publishing date 2024-01-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 243094-0
    ISSN 1528-8951 ; 0148-0731
    ISSN (online) 1528-8951
    ISSN 0148-0731
    DOI 10.1115/1.4064406
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Lack of clinically useful response predictors for treating aggression and agitation in Alzheimer's disease with citalopram.

    Herrmann, Nathan

    Evidence-based mental health

    2016  Volume 19, Issue 4, Page(s) e24

    MeSH term(s) Aggression ; Alzheimer Disease/drug therapy ; Citalopram/therapeutic use ; Humans ; Psychomotor Agitation/drug therapy
    Chemical Substances Citalopram (0DHU5B8D6V)
    Language English
    Publishing date 2016-09-09
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2009065-1
    ISSN 1468-960X ; 1362-0347
    ISSN (online) 1468-960X
    ISSN 1362-0347
    DOI 10.1136/eb-2016-102474
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Bioeconomic analysis of harvesting within a predator-prey system: A case study in the Chesapeake Bay fisheries

    Panayotova, Iordanka N. / Herrmann, John / Kolling, Nathan

    Ecological Modelling. 2023, p.110330-

    2023  , Page(s) 110330–

    Abstract: Sustainable use of biological resources is very important as over exploitation on the long run may lead to stock depletion, which in turn may threaten biodiversity. The Chesapeake Bay is an extremely complex ecosystem, and sustainable harvesting of its ... ...

    Abstract Sustainable use of biological resources is very important as over exploitation on the long run may lead to stock depletion, which in turn may threaten biodiversity. The Chesapeake Bay is an extremely complex ecosystem, and sustainable harvesting of its fisheries is essential both for the ecosystem's biodiversity and economic prosperity of the area. Here, we use ecosystem based mathematical modeling to study the population dynamics with harvesting of two key fishes in the Chesapeake Bay, the Atlantic Menhaden (Brevoortia tyrannus) as a prey and the Striped Bass (Morone saxatilis) as a predator. We start by fitting the generalized Lotka-Volterra model to actual time series abundance data of the two species obtained from fisheries in the Bay. We derive conditions for the existence of the bio-economic equilibrium and investigate the stability and the resilience of the biological system. We study the maximum sustainable yield, maximum economic yield, and resilience maximizing yield policies and their effects on the fisheries long term sustainability, particularly with respect to the menhaden-bass population dynamics. This study may be used by policy-makers to balance the economic and ecological harvesting goals while managing the populations of Atlantic menhaden and striped bass in the Chesapeake Bay fisheries.
    Keywords Brevoortia tyrannus ; Morone saxatilis ; biodiversity ; bioeconomics ; case studies ; ecosystems ; models ; population dynamics ; predator-prey relationships ; time series analysis ; Chesapeake Bay ; Mathematical modeling ; Differential equations ; Predator-prey dynamics ; Harvesting policies ; Maximum sustainable yield ; Maximum economic yield ; Resilience maximizing yield
    Language English
    Publishing place Elsevier B.V.
    Document type Article ; Online
    Note Pre-press version
    ZDB-ID 191971-4
    ISSN 0304-3800
    ISSN 0304-3800
    DOI 10.1016/j.ecolmodel.2023.110330
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Sex-specific neuropsychological correlates of apathy and depression across neurodegenerative disorders.

    Kapustin, Daniel / Tumati, Shankar / Wong, Melissa / Herrmann, Nathan / Dixon, Roger A / Seitz, Dallas / Rapoport, Mark J / Lanctôt, Krista L

    International journal of geriatric psychiatry

    2024  Volume 39, Issue 3, Page(s) e6080

    Abstract: Background: Apathy and depression are common neuropsychiatric symptoms across neurodegenerative disorders and are associated with impairment in several cognitive domains, yet little is known about the influence of sex on these relationships.: ... ...

    Abstract Background: Apathy and depression are common neuropsychiatric symptoms across neurodegenerative disorders and are associated with impairment in several cognitive domains, yet little is known about the influence of sex on these relationships.
    Objectives: We examined the relationship between these symptoms with neuropsychological performance across a combined cohort with mild or major neurodegenerative disorders, then evaluated the impact of sex.
    Design, setting and participants: We conducted a cohort analysis of participants in the COMPASS-ND study with mild cognitive impairment (MCI), vascular MCI, Alzheimer's disease, mixed dementia, Parkinson's disease, frontotemporal dementia, and cognitively unimpaired (CU) controls.
    Measurements: Participants with neurodegenerative disease and CU controls were stratified by the presence (severity ≥1 on Neuropsychiatric Inventory Questionnaire) of either depressive symptoms alone, apathy symptoms alone, both symptoms, or neither. A neuropsychological battery evaluated executive function, verbal fluency, verbal learning, working memory, and visuospatial reasoning. Analysis of covariance was used to assess group differences with age, sex, and education as covariates.
    Results: Groups included depressive symptoms only (n = 70), apathy symptoms only (n = 52), both (n = 68), or neither (n = 262). The apathy and depression + apathy groups performed worse than the neither group on tests of working memory (t
    Conclusions: This study demonstrated that in neurodegenerative diseases, apathy with or without depression in males was associated with broad cognitive impairments. In females, depression was associated with deficits in executive function and verbal learning. These findings highlight the importance of effectively treating apathy and depression across the spectrum of neurodegenerative disorders with the goal of optimizing neuropsychological outcomes.
    MeSH term(s) Female ; Male ; Humans ; Neurodegenerative Diseases ; Apathy ; Depression ; Alzheimer Disease ; Frontotemporal Dementia
    Language English
    Publishing date 2024-03-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 806736-3
    ISSN 1099-1166 ; 0885-6230
    ISSN (online) 1099-1166
    ISSN 0885-6230
    DOI 10.1002/gps.6080
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Transcatheter aortic valve replacement achieves similar predicted effective orifice area to surgical aortic valve replacement in bicuspid aortic stenosis.

    Connolly, John E / Herrmann, Howard C / Atluri, Pavan / Desai, Nimesh / Fiorilli, Paul N / Giri, Jay / Li, Robert H / Kobayashi, Taisei / Nathan, Ashwin S / Szeto, Wilson Y / Grimm, Joshua C

    Cardiovascular revascularization medicine : including molecular interventions

    2024  

    Abstract: Background: Studies comparing transcatheter and surgical aortic valve replacement (TAVR and SAVR) for patients with trileaflet aortic stenosis (AS) have found similar or larger effective orifice area (EOA) for TAVR prostheses. To our knowledge, no ... ...

    Abstract Background: Studies comparing transcatheter and surgical aortic valve replacement (TAVR and SAVR) for patients with trileaflet aortic stenosis (AS) have found similar or larger effective orifice area (EOA) for TAVR prostheses. To our knowledge, no studies have compared EOA in patients undergoing TAVR versus SAVR for bicuspid AS.
    Methods: We retrospectively compared prosthetic valvular sizing and predicted EOA for patients with bicuspid AS undergoing TAVR or SAVR at our institution between January 1, 2016, and December 31, 2021. We excluded patients undergoing procedures for indications other than AS and those without a pre-procedural gated Chest CT. Comparisons included demographics, comorbidities, annular size, prosthetic valve size, predicted EOA and prosthesis-patient mismatch (PPM) for TAVR (N = 78) and SAVR (N = 74) cohorts.
    Results: TAVR patients had smaller pre-procedural annular area (501.7 mm
    Conclusions: For bicuspid AS patients undergoing aortic valve replacement, TAVR achieves similar predicted EOA to SAVR. These data support the use of TAVR in selected patients with bicuspid AS and can inform heart team discussions.
    Language English
    Publishing date 2024-03-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2212113-4
    ISSN 1878-0938 ; 1553-8389
    ISSN (online) 1878-0938
    ISSN 1553-8389
    DOI 10.1016/j.carrev.2024.03.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Novel fluid biomarkers for mild cognitive impairment: A systematic review and meta-analysis.

    Gaur, Amish / Rivet, Luc / Mah, Ethan / Bawa, Kritleen K / Gallagher, Damien / Herrmann, Nathan / Lanctôt, Krista L

    Ageing research reviews

    2023  Volume 91, Page(s) 102046

    Abstract: Mild cognitive impairment (MCI) is a well-established prodromal stage of dementia (e.g., Alzheimer's disease) that is often accompanied by early signs of neurodegeneration. To facilitate a better characterization of the underlying pathophysiology, we ... ...

    Abstract Mild cognitive impairment (MCI) is a well-established prodromal stage of dementia (e.g., Alzheimer's disease) that is often accompanied by early signs of neurodegeneration. To facilitate a better characterization of the underlying pathophysiology, we assessed the available literature to evaluate potential fluid biomarkers in MCI. Peer-reviewed articles that measured cerebrospinal fluid (CSF) and/or peripheral biomarkers of neuronal injury (total-tau [T-tau], neurofilament light chain [NfL], heart-type fatty acid binding protein [HFABP], neuron-specific enolase, ubiquitin C-terminal hydrolase L1) and/or astroglial pathology (glial fibrillary acidic protein [GFAP], S100 calcium-binding protein B) in MCI and healthy controls were assessed. Group differences were summarized by standardized mean differences (SMDs) and 95% confidence intervals calculated using a random-effects model. Heterogeneity was quantified using I
    MeSH term(s) Humans ; Alzheimer Disease/diagnosis ; Cognitive Dysfunction/diagnosis ; tau Proteins ; Biomarkers ; Neurons ; Astrocytes ; Amyloid beta-Peptides
    Chemical Substances tau Proteins ; Biomarkers ; Amyloid beta-Peptides
    Language English
    Publishing date 2023-08-28
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2075672-0
    ISSN 1872-9649 ; 1568-1637
    ISSN (online) 1872-9649
    ISSN 1568-1637
    DOI 10.1016/j.arr.2023.102046
    Database MEDical Literature Analysis and Retrieval System OnLINE

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