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  1. Book: COVID-19 and sleep

    BaHammam, Ahmed S. / Pandi-Perumal, Seithikurippu R. / Jahrami, Haitham

    a global outlook

    (Progress in sleep research)

    2023  

    Author's details Ahmed BaHammam, S.R. Pandi-Perumal, Haitham Jahrami editors
    Series title Progress in sleep research
    Keywords COVID-19 (Disease)/Complications ; Sleep disorders
    Subject code 616.24144
    Language English
    Size xxvi, 430 Seiten, Illustrationen, Diagramme, 24 cm
    Publisher Springer
    Publishing place Singapore
    Publishing country Singapore
    Document type Book
    HBZ-ID HT030056999
    ISBN 978-981-99-0239-2 ; 9789819902408 ; 981-99-0239-8 ; 9819902401
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Cell surface expression of Ribophorin I, an endoplasmic reticulum protein, over different cell types.

    Ahmed, Mohammad Z / Alqahtani, Ali S

    International journal of biological macromolecules

    2024  Volume 264, Issue Pt 1, Page(s) 130278

    Abstract: Ribophorin-1 serves as one of the subunits of the oligosaccharyltransferase (OST) complex located in the endoplasmic reticulum (ER). Until now, RPN-1 was considered an ER protein. However, our findings reveal that a minor fraction of RPN-1 escapes from ... ...

    Abstract Ribophorin-1 serves as one of the subunits of the oligosaccharyltransferase (OST) complex located in the endoplasmic reticulum (ER). Until now, RPN-1 was considered an ER protein. However, our findings reveal that a minor fraction of RPN-1 escapes from the lumen of the ER and is ectopically expressed on the surface of different cell lines. The precise mechanism of protein translocation is unknown. The expression of RPN-1 was demonstrated through the isolation of membrane proteins using surface biotinylation and sucrose density gradient techniques. The confirmation of RPN-1 was obtained through surface staining using a specific antibody, revealing its expression on various cell lines. Additionally, we examined the expression of RPN-1 in different populations of PBMCs and observed a differential regulation of RPN-1 within PBMC subpopulations. Notably, there was a significant expression of RPN-1 on monocytes and B cells, but there was little to no population of T cells expressing RPN-1. We confirmed the expression of RPN-1 on THP-1, U937, and Jurkat cells. We also confirmed their surface expression through si-RNA knockdown. Our study shows RPN-1 expression on various cell surfaces, suggesting varied regulation among cell types. In the future, we may uncover its roles in immune function, signaling, and differentiation/proliferation.
    MeSH term(s) Humans ; Leukocytes, Mononuclear/metabolism ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Endoplasmic Reticulum/metabolism ; Cell Membrane/metabolism ; Glycosyltransferases/metabolism
    Chemical Substances ribophorin ; Membrane Proteins ; Glycosyltransferases (EC 2.4.-)
    Language English
    Publishing date 2024-02-17
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2024.130278
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Detection of Main Causative Agents among Young Children Suffering from Epiglottitis in Hilla City, Iraq.

    Ahmed Ali Ahmed, J / Khalifa, B S / Al-Hasnawy, H H

    Archives of Razi Institute

    2023  Volume 78, Issue 1, Page(s) 315–322

    Abstract: Epiglottitis is a rapidly progressive epiglottis infection leading to upper airway edema. This study aimed to detect the main causative agent, viral infection, by immunofluorescence antibody technique and PCR technique and bacterial infection detection ... ...

    Abstract Epiglottitis is a rapidly progressive epiglottis infection leading to upper airway edema. This study aimed to detect the main causative agent, viral infection, by immunofluorescence antibody technique and PCR technique and bacterial infection detection by specific gene among young children suffering from epiglottitis. This study included 85 young children aged 10-15 years. The virus was identified on 85 blood samples using the CER test Human simplex virus Card test; the results revealed that 12 (14.1%) specimens were related to virus infection, and the sera of patients showed anti-IgM to HSV-1 antibodies. HSV-1 was detected in blood samples by qPCR technique. Eighty-five saliva samples were collected from young children suffering from epiglottitis. The samples were cultured for 18-24 hours at 37°C. They were then cultivated for 18-24 hours on various selective media at 37°C. The colony morphology, microscopically, and biochemical testing were used to identify
    MeSH term(s) Child ; Child, Preschool ; Humans ; Alleles ; Antibodies, Viral ; Culture Media ; Epiglottitis/epidemiology ; Iraq/epidemiology
    Chemical Substances Antibodies, Viral ; Culture Media
    Language English
    Publishing date 2023-02-28
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2555498-0
    ISSN 2008-9872 ; 0365-3439
    ISSN (online) 2008-9872
    ISSN 0365-3439
    DOI 10.22092/ARI.2022.358161.2165
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Correction: Drug-coated balloons versus drug-eluting stents in patients with acute myocardial infarction undergoing percutaneous coronary intervention: an updated meta-analysis with trial sequential analysis.

    Abdelaziz, Ahmed / Hafez, Abdelrahman / Atta, Karim / Elsayed, Hanaa / Abdelaziz, Mohamed / Elaraby, Ahmed / Kadhim, Hallas / Mechi, Ahmed / Ezzat, Mahmoud / Fadel, Ahmed / Nasr, Ahmed / Bakr, Ali / Ghaith, Hazem S

    BMC cardiovascular disorders

    2024  Volume 24, Issue 1, Page(s) 36

    Language English
    Publishing date 2024-01-08
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2059859-2
    ISSN 1471-2261 ; 1471-2261
    ISSN (online) 1471-2261
    ISSN 1471-2261
    DOI 10.1186/s12872-023-03688-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Abdominal distention, immunopositivity, and aggressive nature: A rare Ewing's sarcoma of the adrenal gland.

    Ali, Anam / Shahbaz, Usman / Nadeem, Arsalan / Umar, Sumayya / Ahmed, Abdullah

    Radiology case reports

    2024  Volume 19, Issue 5, Page(s) 1935–1939

    Abstract: ... A percutaneous biopsy verified the tumor's neuroendocrine origin. Extensive involvement of nearby anatomical ...

    Abstract This case report describes a 32-year-old Pakistani male patient with an Ewing sarcoma (ES) of the adrenal gland. Presenting complaints were abdominal distention, pain, low-grade fever, and weight loss. Initial studies, including imaging and tumor markers, ruled out any other possible origins of the mass. A percutaneous biopsy verified the tumor's neuroendocrine origin. Extensive involvement of nearby anatomical structures was discovered through exploratory laparotomy, rendering total resection difficult. Based on the presence of malignant, round, blue cells that were positive for specific immunostaining markers, the histopathology report supported the diagnosis of an ES with a staging of T3N0M0. Chemotherapy, in accordance with the VAC-IE protocol, was administered after debulking surgery. Subsequent imaging and close monitoring revealed no metastatic or residual tumors. Adrenal ES is an uncommon, aggressive tumor that mandates prompt diagnosis and management. This case report highlights the value of early detection and multimodal therapy in enhancing patient outcomes for this rare malignancy.
    Language English
    Publishing date 2024-02-27
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2406300-9
    ISSN 1930-0433
    ISSN 1930-0433
    DOI 10.1016/j.radcr.2024.02.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Neuromuscular Ultrasound in Polyneuropathies.

    Nasr-Eldin, Yasmin K / Cartwright, Michael S / Hamed, Ahmed / Ali, Lamia Hamdy / Abdel-Nasser, Ahmed M

    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine

    2024  

    Abstract: Neuromuscular ultrasound is a painless, radiation-free, high-resolution imaging technique for assessing the peripheral nervous system. It can accurately depict changes in the nerves and muscles of individuals with neuromuscular conditions, and it is ... ...

    Abstract Neuromuscular ultrasound is a painless, radiation-free, high-resolution imaging technique for assessing the peripheral nervous system. It can accurately depict changes in the nerves and muscles of individuals with neuromuscular conditions, and it is therefore a robust diagnostic tool for the assessment of individuals with polyneuropathies. This review will outline the typical ultrasonographic changes found in a wide variety of polyneuropathies. In general, demyelinating conditions result in greater nerve enlargement than axonal conditions, and acquired conditions result in more patchy nerve enlargement compared to diffuse nerve enlargement in hereditary conditions. This review is data-driven, but more nuanced anecdotal findings are also described. The overall goal of this paper is to provide clinicians with an accessible review of the ultrasonographic approaches and findings in a wide variety of polyneuropathies.
    Language English
    Publishing date 2024-03-19
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 604829-8
    ISSN 1550-9613 ; 0278-4297
    ISSN (online) 1550-9613
    ISSN 0278-4297
    DOI 10.1002/jum.16447
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Bioaccumulation of trace metal ions in the blue swimmer crab tissues Portunus pelagicus (Linnaeus, 1758) in Bahrain, Arabian Gulf.

    Khamis, Ahmed S / Naser, Humood A / Ali-Mohamed, Ahmed Y

    Environmental monitoring and assessment

    2023  Volume 195, Issue 9, Page(s) 1022

    Abstract: The blue swimmer crab, Portunus pelagicus, is an edible abundant crustacean found in many seas around the world, including the Arabian Gulf. In this study, the concentrations of six metal ions in the white and brown meats of P. pelagicus from four sites ... ...

    Abstract The blue swimmer crab, Portunus pelagicus, is an edible abundant crustacean found in many seas around the world, including the Arabian Gulf. In this study, the concentrations of six metal ions in the white and brown meats of P. pelagicus from four sites in Bahrain were determined. P. pelagicus was found to accumulate Zn
    MeSH term(s) Male ; Animals ; Female ; Brachyura ; Cadmium ; Bahrain ; Bioaccumulation ; Lead ; Environmental Monitoring ; Water Pollutants, Chemical/analysis ; Trace Elements/analysis ; Risk Assessment ; Metals, Heavy/analysis
    Chemical Substances Cadmium (00BH33GNGH) ; Lead (2P299V784P) ; Water Pollutants, Chemical ; Trace Elements ; Metals, Heavy
    Language English
    Publishing date 2023-08-07
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 782621-7
    ISSN 1573-2959 ; 0167-6369
    ISSN (online) 1573-2959
    ISSN 0167-6369
    DOI 10.1007/s10661-023-11647-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Experimental and Theoretical Study to Increase the Solar-Organic Rankine Cycle Efficiency

    Ali Alshahrany / Ahmed S. Hassan

    Yanbu Journal of Engineering and Science, Vol 20, Iss

    2023  Volume 1

    Abstract: ... of solar thermal power plants (ORC) is simulated with four refrigerants, R144a, R123, R124 and R245fa of working fluid's ...

    Abstract Under conditions of high climate temperature and environmental pollution, scientists are turning to the use of new and renewable energy. The solar Organic Rankin Cycle (ORC) is greatest technology for converting low or medium-temperature energy sources into electricity. For the purpose of generating steam from solar energy to power the organic Rankin cycle a system consists of solar pond, flat plate collector and parabolic dish was designed, implemented, and tested to use in organic Rankin cycle (ORC). The novelty in the present work is the use of the solar pond as storage of heat that does not lose because the salinity gradient middle layer in the pond does not allow heat to pass through it, as well as the use of reheating to enhance the thermodynamic efficiency. Also, an analytical model has been made to enhance the output power and efficiency of the solar thermal ORC according to some organic control criteria. A Cycle of solar thermal power plants (ORC) is simulated with four refrigerants, R144a, R123, R124 and R245fa of working fluid's performance. The cycle net-specific work can be verified at the highest efficiency as a function of turbine extraction numbers, over-temperature, and evaporation temperature. Superheated steam was obtained at a temperature of 327 °C to be used in the Rankin cycle of the solar energy system which is generated in this work. The maximum output power improvement is 9% when using the working fluid R123 for R124, 5.5% for R245fa, and approximately 2.8 for R144a. And the thermal efficiency of ORC is higher with R123 compared to 144a by about 2.2%. Furthermore, it also concluded that both inlet and outlet temperatures of a turbine are very important factors that affect the operational performance of organic Rankin cycle power generation systems.
    Keywords Technology ; T ; Science ; Q
    Subject code 621
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher Yanbu Industrial College
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Herb-Induced Liver Injury by Ayurvedic Medicine With Severe Lactic Acidosis: A Case Report.

    Sharma, Deepak S / Ahmed, Ahmed / Razak, Ali A / Sharma, Priyanka

    Cureus

    2023  Volume 15, Issue 2, Page(s) e34761

    Abstract: Lactate is the basic blood parameter in the arsenal of an intensivist when managing a critically ill patient. A 62-year-old male presented with nausea and vomiting. He had been using an Ayurvedic medication, Insulin Management Expert (IME-9), for his ... ...

    Abstract Lactate is the basic blood parameter in the arsenal of an intensivist when managing a critically ill patient. A 62-year-old male presented with nausea and vomiting. He had been using an Ayurvedic medication, Insulin Management Expert (IME-9), for his type 2 diabetes mellitus and was found to have severe lactic acidosis that was resistant to initial fluid resuscitation and Ayurvedic medicine-induced liver injury. He required admission to critical care for organ support and ultimately recovered. Because current literature on the adverse effects of this Ayurvedic medication, particularly hepatotoxicity, is limited, causality was determined using the adverse drug association tool Roussel Uclaf Causality Assessment Method (RUCAM), which determined this as a probable cause with a strong score of seven. As a result, our case adds a vital gear to the wheel of current research literature.
    Language English
    Publishing date 2023-02-08
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.34761
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Authors' Response: Can a Three-Arm RCT With Two Active Drugs Have One Placebo? Yes, the Literature Contains Many.

    Ashour, Ahmed S A / Ali, Ahmed S

    Journal of pediatric and adolescent gynecology

    2021  Volume 34, Issue 4, Page(s) 577–579

    MeSH term(s) Humans ; Pharmaceutical Preparations ; Randomized Controlled Trials as Topic
    Chemical Substances Pharmaceutical Preparations
    Language English
    Publishing date 2021-03-21
    Publishing country United States
    Document type Letter
    ZDB-ID 1325079-6
    ISSN 1873-4332 ; 1083-3188
    ISSN (online) 1873-4332
    ISSN 1083-3188
    DOI 10.1016/j.jpag.2021.03.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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