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  1. Article: Andrew Szende and the development of the electronic Child Health Network (eCHN).

    Holmes, Morgan

    Healthcare quarterly (Toronto, Ont.)

    2010  Volume 13, Issue 3, Page(s) 26–29

    MeSH term(s) Canada ; Electronic Health Records ; Humans ; Pediatrics ; Program Development
    Language English
    Publishing date 2010-06-11
    Publishing country Canada
    Document type Journal Article
    ISSN 1710-2774
    ISSN 1710-2774
    DOI 10.12927/hcq.2010.21810
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book: Biopesticides manual

    Holmes, Keith / Babendreier, Dirk / Bateman, Melanie

    guidelines for selecting, sourcing, producing and using biopesticides for key pests of tobacco

    2018  

    Abstract: Introduction to the biopesticides manual -- Selecting biopesticides -- Sourcing biopesticides -- Training guide for field technicians and farmers: biopesticides and how to work with them. ...

    Author's details Keith Holmes, Dirk Babendreier, Melanie Bateman [und 5 weitere]
    Abstract Introduction to the biopesticides manual -- Selecting biopesticides -- Sourcing biopesticides -- Training guide for field technicians and farmers: biopesticides and how to work with them.
    Keywords Tobacco / Diseases and pests / Biological control ; Natural pesticides ; Pests / Integrated control
    Language English
    Size xi, 145 Seiten
    Publisher CABI
    Publishing place Wallingford ; Boston, MA
    Publishing country Great Britain
    Document type Book
    Note Includes bibliographical references and index.
    HBZ-ID HT020194224
    ISBN 978-1-78924-202-7 ; 9781789242010 ; 1-78924-202-9 ; 1789242010
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    198/194 available for loan (reading room) Freihandmagazin (U1)

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  3. Article ; Online: GDF11 reverses mood and memory declines in aging.

    Piantadosi, Patrick T / Holmes, Andrew

    Nature aging

    2023  Volume 3, Issue 2, Page(s) 148–150

    MeSH term(s) Humans ; Aging ; Growth Differentiation Factors ; Memory Disorders ; Bone Morphogenetic Proteins
    Chemical Substances Growth Differentiation Factors ; GDF11 protein, human ; Bone Morphogenetic Proteins
    Language English
    Publishing date 2023-04-26
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Intramural ; Comment
    ISSN 2662-8465
    ISSN (online) 2662-8465
    DOI 10.1038/s43587-023-00362-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Low sugar and the drive to breathe: Is insulin another adequate stimulus for the carotid body?

    Holmes, Andrew P / Kumar, Prem

    Experimental physiology

    2023  Volume 108, Issue 2, Page(s) 167–168

    MeSH term(s) Humans ; Insulin ; Carotid Body ; Sugars ; Epinephrine ; Hypoglycemia ; Blood Glucose
    Chemical Substances Insulin ; Sugars ; Epinephrine (YKH834O4BH) ; Blood Glucose
    Language English
    Publishing date 2023-01-18
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1016295-1
    ISSN 1469-445X ; 0958-0670
    ISSN (online) 1469-445X
    ISSN 0958-0670
    DOI 10.1113/EP091008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.102: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Biological clues to an enigmatic treatment for traumatic stress.

    Holmes, Andrew

    Nature

    2019  Volume 566, Issue 7744, Page(s) 335–336

    MeSH term(s) Clinical Protocols ; Fear ; Humans ; Stress Disorders, Post-Traumatic
    Language English
    Publishing date 2019-02-19
    Publishing country England
    Document type News ; Comment
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/d41586-019-00294-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 26: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 9: Show issues
    Zs.MO 244: Show issues

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  6. Article ; Online: The neuroscience and genomics of social behavior.

    Holmes, Andrew

    Genes, brain, and behavior

    2019  Volume 18, Issue 1, Page(s) e12551

    MeSH term(s) Animals ; Genetics, Behavioral/methods ; Genomics/methods ; Humans ; Neurosciences/methods ; Social Behavior
    Language English
    Publishing date 2019-01-21
    Publishing country England
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 2075819-4
    ISSN 1601-183X ; 1601-1848
    ISSN (online) 1601-183X
    ISSN 1601-1848
    DOI 10.1111/gbb.12551
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5642: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: The Association of Guideline-Directed Prophylaxis With Postoperative Nausea and Vomiting in Adult Patients: A Single-Center, Retrospective Cohort Study.

    Andrew, Benjamin Y / Holmes, Romel / Taicher, Brad M / Habib, Ashraf S

    Anesthesia and analgesia

    2024  

    Abstract: Background: Consensus guidelines for postoperative nausea and vomiting (PONV) prophylaxis recommend a risk-based approach in which the number of antiemetics administered is based on a preoperative estimate of PONV risk. These guidelines have been ... ...

    Abstract Background: Consensus guidelines for postoperative nausea and vomiting (PONV) prophylaxis recommend a risk-based approach in which the number of antiemetics administered is based on a preoperative estimate of PONV risk. These guidelines have been adapted by the Multicenter Perioperative Outcomes Group (MPOG) to serve as measures of clinician and hospital compliance with guideline-recommended care. However, the impact of this approach on clinical outcomes is not known.
    Methods: We performed a single-center, retrospective study of adult patients undergoing general anesthesia from 2018 to 2021. Risk factors for PONV were defined using MPOG definitions: female sex, history of PONV or motion sickness, nonsmoker, inhaled anesthesia >60 minutes, high-risk procedure (cholecystectomy, laparoscopic, gynecologic), and age <50 years. Adequate prophylaxis was defined using the MPOG PONV-05 metric: at least 2 agents for patients with 1 to 2 risk factors and at least 3 agents for patients with 3+ risk factors. PONV was defined as documented PONV or receipt of rescue antiemetics. To estimate the association between adequate prophylaxis and PONV, we used Bayesian binomial models with overlap propensity score weighting.
    Results: We included 76,703 cases (43% receiving adequate prophylaxis) with PONV occurring in 19%. In unadjusted and unweighted comparison, adequate prophylaxis was associated with increased incidence of PONV: median odds ratio 1.21 (95% credible interval [1.16-1.25]). However, after propensity score weighting and multivariable adjustment, adequate prophylaxis was associated with reduced relative and absolute risk for PONV: weighted marginal median odds ratio 0.90 [0.84-0.98] and absolute risk reduction (ARR) 1.6% [0.6%-2.6%]. There was evidence for a differential effect of adequate prophylaxis across the guideline-defined risk spectrum, with benefit seen in patients with 1 to 5 risk factors (conditional probabilities of benefit >0.81), but not in those at high predicted risk. Patient-specific, covariate-adjusted ARR was heterogeneous, with a median patient-specific conditional probability of benefit of 0.84 (95% credible interval, 0.73-0.90).
    Conclusions: Guideline-directed PONV prophylaxis is associated with a modest reduction in PONV, although this effect is small and heterogeneous on the absolute scale. We found evidence for a differential association between adequate prophylaxis and PONV across the guideline-defined risk spectrum, with diminution in patients at very high predicted preoperative risk. While patient-specific benefit was heterogenous, most patients had reasonably high predicted probabilities of absolute benefit from a guideline-directed strategy. Further assessment of these associations in a multicenter setting, with more robust investigation of risk prediction methods will allow for better understanding of the optimal approach to PONV prophylaxis.
    Language English
    Publishing date 2024-01-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000006855
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.78: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 149: Show issues

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  8. Article ; Online: Damage control: carotid body activation and remodelling in response to aseptic tissue injury.

    Holmes, Andrew P

    Experimental physiology

    2020  Volume 105, Issue 9, Page(s) 1467–1469

    MeSH term(s) Animals ; Carotid Body ; Gene Expression ; Hypoxia ; Neurotransmitter Agents ; Rats ; Synaptic Transmission
    Chemical Substances Neurotransmitter Agents
    Keywords covid19
    Language English
    Publishing date 2020-08-12
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1016295-1
    ISSN 1469-445X ; 0958-0670
    ISSN (online) 1469-445X
    ISSN 0958-0670
    DOI 10.1113/EP088923
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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.102: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Sex and Orexins: Uncovering a Mechanism Underlying Sex Differences in Stress Susceptibility.

    Holmes, Andrew

    Biological psychiatry

    2017  Volume 81, Issue 8, Page(s) 642–644

    Language English
    Publishing date 2017-04-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209434-4
    ISSN 1873-2402 ; 0006-3223
    ISSN (online) 1873-2402
    ISSN 0006-3223
    DOI 10.1016/j.biopsych.2017.02.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 720: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Applying weight of evidence methods to assessing exposure in aquatic environments: Comparing lines of evidence.

    Miglino, Andrew N / Holmes, Christopher M

    Integrated environmental assessment and management

    2022  Volume 19, Issue 5, Page(s) 1207–1219

    Abstract: Weight of evidence (WoE) is a useful approach to quantifying the relative relevance, strength, reliability, and uncertainty associated with estimates of exposure concentrations. WoE is often used in exposure assessments but rarely explored or discussed ... ...

    Abstract Weight of evidence (WoE) is a useful approach to quantifying the relative relevance, strength, reliability, and uncertainty associated with estimates of exposure concentrations. WoE is often used in exposure assessments but rarely explored or discussed in detail. In this article, the utility of a WoE approach in aquatic exposure assessments is illustrated via two case studies using a tiered approach and the chemical triclosan. Each case study evaluates the same chemical and pathway to the environment but with substantially different data strength, reliability, and uncertainty. The collection and qualitative evaluation of relevant lines of evidence (LoE) using a three-tiered approach are discussed. Our results demonstrate how a higher tiered WoE approach can reduce uncertainty and improve decision-making based on predicted exposure concentrations. We also identify LoE that played a significant role in the final exposure determinations and describe a framework for conducting exposure assessments using WoE. Integr Environ Assess Manag 2023;19:1207-1219. © 2022 SETAC.
    MeSH term(s) Reproducibility of Results ; Risk Assessment/methods
    Language English
    Publishing date 2022-04-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2234931-5
    ISSN 1551-3793 ; 1551-3777
    ISSN (online) 1551-3793
    ISSN 1551-3777
    DOI 10.1002/ieam.4602
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 7647: Show issues

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