LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 96

Search options

  1. Article: The Efficacy of "Care for Child Development" Intervention on the Improvement of the Development Skills of Orphanage Children.

    Baraheni, Nasrin / Heidarabadi, Seifollah / Maleki, Zahra / Azhdarzadeh, Fatemeh / Bahari Gharehgoz, Ali / Bagheri, Zahra

    Iranian journal of child neurology

    2023  Volume 17, Issue 4, Page(s) 83–91

    Abstract: Objectives: Development refers to the progressive enhancement of skills and functional capacity, i.e., qualitative changes in the child's functions. The process of development begins before birth and continues throughout life. The present study aims to ... ...

    Abstract Objectives: Development refers to the progressive enhancement of skills and functional capacity, i.e., qualitative changes in the child's functions. The process of development begins before birth and continues throughout life. The present study aims to evaluate the effectiveness of the "Care for Child Development (CCD)" program on 4-42 months children's developmental skills in orphanages.
    Materials and methods: In this study, two orphanages in the capitals of East and West Azerbaijan provinces were selected using the convenience sampling technique, and thirty children were included. Then, they were randomly divided into two intervention and control groups (each group, N=15). Next, after obtaining consent from the head of the orphanages, a group of volunteers from the healthcare center performed the CCD program, considering children's chronological ages (4 to 42 months), for three sessions a week, with each session lasting two hours and it lasted for three months. At the end of the intervention process, the Bayley Scale of Infant and Toddler Development 3
    Results: Comparing the two control and intervention groups using the T-test (difference in mean) indicates that except for the domain of cognitive skills (Bayley: P-value = 0.176), there was statistically a significant difference between the two groups in communication (ASQ: P-value = 0.001; Bayley: P-value = 0.003), motor (ASQ: P-value = 0.000; Bayley: P-value = 0.009), and personal-social (ASQ: P-value <0.000) skills.
    Conclusion: In the present study, it was concluded that it is required to apply interventions, including standard ones such as the CCD program in environments like orphanages, to enhance the developmental skills of those children living in them.
    Language English
    Publishing date 2023-10-26
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2542305-8
    ISSN 2008-0700 ; 1735-4668
    ISSN (online) 2008-0700
    ISSN 1735-4668
    DOI 10.22037/ijcn.v17i2.38644
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article: Genetic Variations of Angiotensinogen, Angiotensin Converting Enzyme, and Angiotensin Type 1 Receptor with the Risk of Pulmonary Tuberculosis.

    Kouhpayeh, Hamidreza / Naderi, Mohammad / Mohammadghasemipour, Zahra / Bahari, Gholamreza / Elahian, Nastaran / Taheri, Mohsen / Hashemi, Mohammad

    Prague medical report

    2024  Volume 125, Issue 1, Page(s) 5–14

    Abstract: There is little data regarding the impact of renin-angiotensin system (RAS) gene polymorphisms on tuberculosis. The current study designed to survey the possible association between RAS polymorphisms and the risk of pulmonary tuberculosis (PTB) in a ... ...

    Abstract There is little data regarding the impact of renin-angiotensin system (RAS) gene polymorphisms on tuberculosis. The current study designed to survey the possible association between RAS polymorphisms and the risk of pulmonary tuberculosis (PTB) in a sample of the southeast Iranian population. This case-control study was done on 170 PTB patients and 170 healthy subjects. The AGT rs699 C>T, ACE rs4341 C>G and AT1R rs5186 C>A variants were genotyped using polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) and ACE rs4646994 (287bp I/D) variant by PCR method. Regarding AT1R rs5186 A>C polymorphism, the findings revealed that AC genotype and C allele significantly decreased the risk of PTB (OR=0.39, 95% CI=0.22-0.67, p=0.001, and OR=0.53, 95% CI=0.25-0.72, p=0.002, C vs. A, respectively). The TC genotype and C allele of AGT rs699 T>C significantly associated with decreased the risk of PTB (OR=0.45, 95% CI=0.28-0.74, p=0.002, TC vs. TT and OR=0.51, 95% CI=0.32-0.80, p=0.005, C vs. T, respectively). The ID genotype of ACE 287bp I/D significantly increased the risk of PTB (OR=1.88, 95% CI=1.12-3.17, p=0.017). Our finding did not support an association between ACE rs4341 C>G variant and the risk of PTB. In summary, the findings revealed an association between AT1R rs5186 A>C, AGT rs699 T>C and ACE 287bp I/D polymorphisms and the risk of PTB in a sample of the southeast Iranian population. Further investigation with higher sample sizes and diverse ethnicities are required to confirm our findings.
    MeSH term(s) Humans ; Angiotensinogen/genetics ; Case-Control Studies ; Genetic Predisposition to Disease ; Genotype ; Iran/epidemiology ; Peptidyl-Dipeptidase A/genetics ; Polymorphism, Genetic ; Receptor, Angiotensin, Type 1/genetics ; Tuberculosis, Pulmonary/genetics
    Chemical Substances Angiotensinogen (11002-13-4) ; Peptidyl-Dipeptidase A (EC 3.4.15.1) ; Receptor, Angiotensin, Type 1 ; AGTR1 protein, human ; ACE protein, human (EC 3.4.15.1) ; AGT protein, human
    Language English
    Publishing date 2024-02-21
    Publishing country Czech Republic
    Document type Journal Article
    ZDB-ID 2148569-0
    ISSN 1214-6994
    ISSN 1214-6994
    DOI 10.14712/23362936.2024.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: The effects of Lavandula angustifolia essential oil on analgesic effects and percutaneous absorption of naproxen sodium gel; an in vivo and in vitro study.

    Rostamkalaei, Seyyed Sohrab / Iman, Maryam / Ataee, Ramin / Bahari, Zahra

    Clinical and experimental pharmacology & physiology

    2023  Volume 50, Issue 4, Page(s) 298–306

    Abstract: The percutaneous bioavailability of naproxen is low and several technologies have been utilized to overcome the problem. Although, some studies have reported the permeation-enhancing properties of natural essential oils, no research has reflected the ... ...

    Abstract The percutaneous bioavailability of naproxen is low and several technologies have been utilized to overcome the problem. Although, some studies have reported the permeation-enhancing properties of natural essential oils, no research has reflected the effectiveness of Lavandula angustifolia essential oil (LAEO) on increasing the percutaneous absorption of naproxen sodium from a topical gel. Therefore, the present study was designed to investigate whether LAEO increased the percutaneous absorption and the analgesic effects of naproxen sodium topical gel. In the present study, naproxen topical gel was formulated using carbopol 940 (a gelling agent) and several vehicles such as PEG 400, ethanol, and water and the properties of gels were measured. Percutaneous absorption-enhancing properties of LAEO were measured too. Based on our data, the essential oil-containing formulation of naproxen represented greater penetration into (222.19 ± 24.87 vs. 107.65 ± 6.38 μg/cm
    MeSH term(s) Skin Absorption ; Naproxen ; Lavandula ; Oils, Volatile/pharmacology ; Gels
    Chemical Substances Naproxen (57Y76R9ATQ) ; Oils, Volatile ; Gels
    Language English
    Publishing date 2023-01-11
    Publishing country Australia
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 189277-0
    ISSN 1440-1681 ; 0305-1870 ; 0143-9294
    ISSN (online) 1440-1681
    ISSN 0305-1870 ; 0143-9294
    DOI 10.1111/1440-1681.13747
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Correction: Predictors of patient safety competency among emergency nurses in Iran: a cross-sectional correlational study.

    Soola, Ibi / Ajri-Khameslou, Mehdi / Mirzaei, Alireza / Bahari, Zahra

    BMC health services research

    2022  Volume 22, Issue 1, Page(s) 654

    Language English
    Publishing date 2022-05-16
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2050434-2
    ISSN 1472-6963 ; 1472-6963
    ISSN (online) 1472-6963
    ISSN 1472-6963
    DOI 10.1186/s12913-022-08016-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Effects of sumac supplementation on lipid profile: A systematic review and meta-analysis of randomized controlled trials.

    Bahari, Hossein / Taheri, Shaghayegh / Namkhah, Zahra / Barghchi, Hanieh / Arzhang, Pishva / Nattagh-Eshtivani, Elyas

    Phytotherapy research : PTR

    2023  Volume 38, Issue 1, Page(s) 241–252

    Abstract: This systematic review aimed to gather data on the effects of sumac supplementation on lipid profile. A systematic literature search was carried out using electronic databases (PubMed, Scopus, and Web of Science) up to March 2023 to identify eligible ... ...

    Abstract This systematic review aimed to gather data on the effects of sumac supplementation on lipid profile. A systematic literature search was carried out using electronic databases (PubMed, Scopus, and Web of Science) up to March 2023 to identify eligible randomized controlled trials (RCTs) assessing the effects of sumac intake on lipid profile as an outcome. All participants enrolled in our study were adult individuals who consumed sumac, in various forms, as an intervention. The included articles were assessed using the Cochrane risk of bias assessment tool. Heterogeneity tests of the selected trials were performed using the I
    MeSH term(s) Adult ; Humans ; Cholesterol, HDL/blood ; Cholesterol, LDL/blood ; Dietary Supplements ; Lipids/blood ; Randomized Controlled Trials as Topic ; Rhus/chemistry ; Triglycerides ; Plant Extracts/therapeutic use ; Hyperlipidemias/drug therapy
    Chemical Substances Cholesterol, HDL ; Cholesterol, LDL ; Lipids ; Triglycerides ; Plant Extracts
    Language English
    Publishing date 2023-10-21
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 639136-9
    ISSN 1099-1573 ; 0951-418X
    ISSN (online) 1099-1573
    ISSN 0951-418X
    DOI 10.1002/ptr.8046
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Creatine supplementation protects spatial memory and long-term potentiation against chronic restraint stress.

    Bahari, Zahra / Jangravi, Zohreh / Hatef, Boshra / Valipour, Habib / Meftahi, Gholam Hossein

    Behavioural pharmacology

    2023  Volume 34, Issue 6, Page(s) 330–339

    Abstract: Stress contributes to numerous psychopathologies, including memory impairment, and threatens one's well-being. It has been reported that creatine supplementation potentially influences cognitive processing. Hence, in this study, we examined the effects ... ...

    Abstract Stress contributes to numerous psychopathologies, including memory impairment, and threatens one's well-being. It has been reported that creatine supplementation potentially influences cognitive processing. Hence, in this study, we examined the effects of creatine supplementation on memory, synaptic plasticity, and neuronal arborization in the CA1 region of the hippocampus in rats under chronic restraint stress (CRS). Thirty-two adult male Wistar rats (8 weeks old) weighing 200-250 g were randomly divided into four groups (n = 8/per group): control, stress, creatine, and stress + creatine. CRS was induced for 6 h per day for 14 days, and creatine supplementation was carried out by dissolving creatine (2 g/kg body weight per day) in the animals' drinking water for 14 days. We used the Barnes maze and shuttle box for spatial and passive avoidance memory examination. The in-vivo field potential recording and Golgi-Cox staining were also used to investigate long-term potentiation (LTP) and dendrite arborization in the CA1 pyramidal neurons. Chronic stress impaired spatial memory, dysregulated LTP parameters, and decreased the number of dendrites in the CA1 pyramidal neurons of stressed rats, and creatine supplementation modified these effects in stressed rats. It seems that creatine supplementation can improve spatial memory deficits and synaptic plasticity loss induced by CRS in hippocampal CA1 neurons, possibly by reducing the dendrite arborization damages. However, understanding its mechanism needs further investigation.
    MeSH term(s) Rats ; Male ; Animals ; Long-Term Potentiation/physiology ; Creatine/pharmacology ; Spatial Memory ; Rats, Wistar ; Hippocampus ; Neuronal Plasticity ; Memory Disorders/drug therapy ; Dietary Supplements ; Maze Learning
    Chemical Substances Creatine (MU72812GK0)
    Language English
    Publishing date 2023-07-14
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1027374-8
    ISSN 1473-5849 ; 0955-8810
    ISSN (online) 1473-5849
    ISSN 0955-8810
    DOI 10.1097/FBP.0000000000000739
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Correction

    ibi Soola / Mehdi Ajri-Khameslou / Alireza Mirzaei / Zahra Bahari

    BMC Health Services Research, Vol 22, Iss 1, Pp 1-

    Predictors of patient safety competency among emergency nurses in Iran: a cross-sectional correlational study

    2022  Volume 1

    Keywords Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  8. Article ; Online: Spinal α

    Bahari, Zahra / Meftahi, Gholam Hossein

    British journal of pharmacology

    2019  Volume 176, Issue 14, Page(s) 2366–2381

    Abstract: Neuropathic pain can arise from disease or damage to the nervous system. The most common symptoms of neuropathic pain include spontaneous pain, allodynia, and hyperalgesia. There is still limited knowledge about the factors that initiate and maintain ... ...

    Abstract Neuropathic pain can arise from disease or damage to the nervous system. The most common symptoms of neuropathic pain include spontaneous pain, allodynia, and hyperalgesia. There is still limited knowledge about the factors that initiate and maintain neuropathic pain. However, ample evidence has proved the antinociceptive role of spinal α-adrenoceptors following nerve injury. It is well-documented that noradrenergic descending pathways from supraspinal loci exert an inhibitory influence on the spinal cord nociceptive neurons, mostly through the activation of spinal α
    MeSH term(s) Adrenergic Agonists/pharmacology ; Animals ; Humans ; Neuralgia/drug therapy ; Neuralgia/metabolism ; Receptors, Adrenergic, alpha-2/metabolism ; Spine/drug effects ; Spine/metabolism
    Chemical Substances Adrenergic Agonists ; Receptors, Adrenergic, alpha-2
    Language English
    Publishing date 2019-03-06
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 80081-8
    ISSN 1476-5381 ; 0007-1188
    ISSN (online) 1476-5381
    ISSN 0007-1188
    DOI 10.1111/bph.14580
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: Effect of sodium substitution by yttrium on the structural, dielectric and electrical properties of Ba

    Yahakoub, El Hassan / Bendahhou, Amine / Jalafi, Ilyas / Chaou, Fatima / El Barkany, Soufian / Bahari, Zahra / Abou-Salama, Mohamed

    Heliyon

    2023  Volume 9, Issue 11, Page(s) e21037

    Abstract: The effects of ... ...

    Abstract The effects of Na
    Language English
    Publishing date 2023-10-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e21037
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: The anti-cancer properties of neem (

    Iman, Maryam / Taheri, Mohammadreza / Bahari, Zahra

    Journal of complementary & integrative medicine

    2021  Volume 19, Issue 2, Page(s) 203–211

    Abstract: Objectives: The neem (: Methods: A systematic search in the literature was performed in PubMed, Scopus, Embase, Cochrane Library, Web of Science, as well as Google Scholar pre-print database using all available MeSH terms for neem, : Results: The ... ...

    Abstract Objectives: The neem (
    Methods: A systematic search in the literature was performed in PubMed, Scopus, Embase, Cochrane Library, Web of Science, as well as Google Scholar pre-print database using all available MeSH terms for neem,
    Results: The neem plant have been used in herbal medicine for the treatment of various diseases, particularly cancer. The mechanisms of anti-cancer effects of neem are far from clear. Cancerous cells growth can induce imbalance the oxidant and anti-oxidant activity in various organs particularly in the liver. Therefore, it seems that neem have anti-cancer effects via restore of the antioxidant disturbances close to the control ones in the liver. Additionally, administration of neem extract can induce oncostatic potential via several mechanism including; suppression of the NF-κβ pathway, increased expression of tumor suppressor (such as p53 and pTEN), decreased expression of oncogenes (such as c-Myc), and increased apoptosis in cancerous cells. The median lethal dose (LD50) value for extracts of neem was higher than 2,500 mg/kg.
    Conclusions: It is suggested that neem plays pivotal role in the prevention and treatment of cancer via its hepatic antioxidant activity. Indeed, application of neem extract can decreased tumor growth via restore of the antioxidant disturbances close to the control ones in the liver.
    MeSH term(s) Antioxidants/pharmacology ; Antioxidants/therapeutic use ; Azadirachta ; Biopharmaceutics ; Humans ; Liver ; Neoplasms/drug therapy ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use ; Plant Leaves
    Chemical Substances Antioxidants ; Plant Extracts
    Language English
    Publishing date 2021-05-10
    Publishing country Germany
    Document type Journal Article ; Review ; Systematic Review
    ZDB-ID 2197618-1
    ISSN 1553-3840 ; 2194-6329
    ISSN (online) 1553-3840
    ISSN 2194-6329
    DOI 10.1515/jcim-2021-0009
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top