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Article ; Online: Sleep disorders and disrupted sleep in addiction, withdrawal and abstinence with focus on alcohol and opioids.

Reid-Varley, William-Bernard / Ponce Martinez, Caridad / Khurshid, Khurshid A

2020 Volume 411, Page(s) 116713

MeSH term(s)	Alcoholism/complications ; Analgesics, Opioid/adverse effects ; Ethanol/pharmacology ; Humans ; Sleep ; Sleep Wake Disorders/drug therapy ; Substance Withdrawal Syndrome
Chemical Substances	Analgesics, Opioid ; Ethanol (3K9958V90M)
Language	English
Publishing date	2020-01-30
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	80160-4
ISSN	1878-5883 ; 0022-510X ; 0374-8642
ISSN (online)	1878-5883
ISSN	0022-510X ; 0374-8642
DOI	10.1016/j.jns.2020.116713
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Article ; Online: Cases That Haunt Us: The Rashomon Effect and Moral Distress on the Consult Service.

Ponce Martinez, Caridad / Suratt, Colleen E / Chen, Donna T

Psychosomatics

2016 Volume 58, Issue 2, Page(s) 191–196

MeSH term(s)	Adult ; Anorexia Nervosa/complications ; Anorexia Nervosa/psychology ; Anorexia Nervosa/therapy ; Bullying ; Depressive Disorder/complications ; Depressive Disorder/psychology ; Depressive Disorder/therapy ; Ethics Committees, Clinical ; Failure to Thrive/complications ; Failure to Thrive/psychology ; Failure to Thrive/therapy ; Humans ; Male ; Malnutrition/complications ; Malnutrition/psychology ; Malnutrition/therapy ; Mental Competency ; Morals ; Occupational Stress/psychology ; Proxy ; Psychiatry/ethics ; Referral and Consultation ; Stress Disorders, Post-Traumatic/complications ; Stress Disorders, Post-Traumatic/psychology ; Stress Disorders, Post-Traumatic/therapy ; Stress, Psychological ; Suicidal Ideation ; Thinness/complications ; Thinness/psychology ; Thinness/therapy ; Treatment Refusal/ethics ; Violence ; Wounds and Injuries/complications ; Wounds and Injuries/psychology ; Wounds and Injuries/therapy
Language	English
Publishing date	2016-09-19
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	209487-3
ISSN	1545-7206 ; 0033-3182
ISSN (online)	1545-7206
ISSN	0033-3182
DOI	10.1016/j.psym.2016.09.008
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Article: Pharmacotherapy for Alcohol Use Disorders: Physicians' Perceptions and Practices.

Ponce Martinez, Caridad / Vakkalanka, Priyanka / Ait-Daoud, Nassima

Frontiers in psychiatry

2016 Volume 7, Page(s) 182

Abstract: Background and objectives: Alcohol use disorders (AUDs) are an important cause of morbidity and mortality. Despite the National Institute on Alcohol Abuse and Alcoholism (NIAAA) recommendations that medications be considered for patients with alcohol ... ...

Abstract	Background and objectives: Alcohol use disorders (AUDs) are an important cause of morbidity and mortality. Despite the National Institute on Alcohol Abuse and Alcoholism (NIAAA) recommendations that medications be considered for patients with alcohol dependence, the mainstay of treatment has been counseling. We designed a survey to assess the treatment practices of psychiatrists and family medicine (FM) physicians in an effort to identify barriers to the use of pharmacotherapy and develop strategies to increase physician knowledge and utilization of these medications. Methods: An anonymous online survey was sent to FM physicians and psychiatrists nationwide. The survey collected demographic information and assessed prescription of medications in treating AUDs, including FDA-approved medications and other medications used off-label for this purpose. We also examined factors that would lead to an increase in AUDs pharmacotherapy. Results: A total of 491 surveys were completed, with 475 responses included in the final analyses. 45.5% of participants were psychiatrists vs. 54.5% FM physicians. The 74.7% respondents had used medications to treat AUDs, with psychiatrists more likely to have prescribed acamprosate, naltrexone, and several off-label medications. FM physicians were more likely to report efficacy concerns. A majority of all physicians sampled would increase pharmacotherapy of AUDs with increased training. Discussion: In our sample, most physicians have used medications to treat AUDs. There were concerns about efficacy with all non-FDA-approved medications, but limited treatment success even with FDA-approved medications. Greater education about pharmacotherapy, including predictors for treatment response amongst patients, should help alleviate some of the uncertainties reported with medications' efficacy and lead to a more individualized treatment approach.
Language	English
Publishing date	2016-11-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564218-2
ISSN	1664-0640
ISSN	1664-0640
DOI	10.3389/fpsyt.2016.00182
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Article ; Online: Associations Among Sleep Disturbance, Pain Catastrophizing, and Pain Intensity for Methadone-maintained Patients With Opioid Use Disorder and Chronic Pain.

Ponce Martinez, Caridad / Edwards, Karlyn A / Roos, Corey R / Beitel, Mark / Eller, Anthony / Barry, Declan T

The Clinical journal of pain

2020 Volume 36, Issue 9, Page(s) 641–647

Abstract: Objective: This study examined the cross-sectional associations among pain intensity, pain catastrophizing, and sleep disturbance among patients receiving methadone maintenance treatment (MMT) for opioid use disorder (OUD) and reporting co-occurring ... ...

Abstract	Objective: This study examined the cross-sectional associations among pain intensity, pain catastrophizing, and sleep disturbance among patients receiving methadone maintenance treatment (MMT) for opioid use disorder (OUD) and reporting co-occurring chronic pain. Materials and methods: Participants were 89 individuals with OUD and chronic pain drawn from a larger cross-sectional study of 164 MMT patients who completed a battery of self-report measures. The authors conducted 6 mediation models to test all possible pathways (ie, each variable tested as an independent variable, mediator, or dependent variable). Results: The only significant mediation effect was an indirect effect of sleep disturbance on pain intensity through pain catastrophizing. That is, greater sleep disturbance was associated with greater pain catastrophizing, which in turn was associated with greater pain intensity. Discussion: Altogether, findings suggest that the sleep disturbance to pain catastrophizing to pain intensity pathway may be a key mechanistic pathway exacerbating pain issues among MMT patients with OUD and chronic pain. These results suggest that interventions targeting sleep disturbance may be warranted among MMT patients with OUD and chronic pain. Future work in this area with longitudinal data is warranted.
MeSH term(s)	Adult ; Catastrophization ; Chronic Pain/drug therapy ; Cross-Sectional Studies ; Female ; Humans ; Male ; Methadone/therapeutic use ; Middle Aged ; Opioid-Related Disorders/drug therapy ; Sleep Wake Disorders
Chemical Substances	Methadone (UC6VBE7V1Z)
Language	English
Publishing date	2020-06-01
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	632582-8
ISSN	1536-5409 ; 0749-8047
ISSN (online)	1536-5409
ISSN	0749-8047
DOI	10.1097/AJP.0000000000000848
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Article ; Online: Sexual dysfunction associated with major depressive disorder and antidepressant treatment.

Clayton, Anita H / El Haddad, Saria / Iluonakhamhe, Josepha-Pearl / Ponce Martinez, Caridad / Schuck, Alexandra Elizabeth

Expert opinion on drug safety

2014 Volume 13, Issue 10, Page(s) 1361–1374

Abstract: Introduction: There is a well-established relationship between sexual functioning and quality of life. Depression can cause sexual dysfunction (SD) and its treatment can often lead to restoration of sexual functioning. Use of antidepressants has also ... ...

Abstract	Introduction: There is a well-established relationship between sexual functioning and quality of life. Depression can cause sexual dysfunction (SD) and its treatment can often lead to restoration of sexual functioning. Use of antidepressants has also been associated with SD, with implications for treatment compliance and creation of further distress for the patient. Areas covered: This review evaluates available information regarding SD related to both depression and antidepressant treatment, including literature up to June 2014. It includes eligible published studies that investigated antidepressant-associated SD (AASD). Expert opinion: Depression and SD have a bidirectional association. When screening for depression, baseline sexual functioning should be assessed with validated rating scales. If sexual side effects develop with antidepressant treatment, management options include waiting for spontaneous remission, decreasing the medication dose, switching to an alternative drug or adding an augmentation agent or antidote. Research suggests that bupropion and newer antidepressants exhibit a more favorable SD profile compared with other antidepressants, especially selective serotonin reuptake inhibitors and serotonin and norepinephrine reuptake inhibitors. Bupropion, mirtazapine and buspirone have been studied as augmentation agents/antidotes or substitution agents in management of AASD. Future studies validating genetic factors could enable personal genotyping to guide individualized treatment and also facilitate the development of enhanced therapeutic guidelines to avoid or manage AASD.
MeSH term(s)	Animals ; Antidepressive Agents/administration & dosage ; Antidepressive Agents/adverse effects ; Antidepressive Agents/therapeutic use ; Depressive Disorder, Major/complications ; Depressive Disorder, Major/drug therapy ; Genetic Predisposition to Disease ; Humans ; Medication Adherence ; Practice Guidelines as Topic ; Psychiatric Status Rating Scales ; Quality of Life ; Sexual Dysfunction, Physiological/chemically induced ; Sexual Dysfunction, Physiological/epidemiology ; Sexual Dysfunction, Physiological/etiology
Chemical Substances	Antidepressive Agents
Language	English
Publishing date	2014-10
Publishing country	England
Document type	Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	2088728-0
ISSN	1744-764X ; 1474-0338
ISSN (online)	1744-764X
ISSN	1474-0338
DOI	10.1517/14740338.2014.951324
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Zs.A 6096: Show issues

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Article ; Online: Training addiction counselors to deliver a brief psychoeducational intervention for chronic pain among patients in opioid agonist treatment: A pilot investigation.

Butner, Jenna L / Bone, Curtis / Ponce Martinez, Caridad C / Kwon, Grace / Beitel, Mark / Madden, Lynn M / Bono, Madeline H / Eller, Anthony / Barry, Declan T

Substance abuse

2018 Volume 39, Issue 2, Page(s) 199–205

Abstract: Background: Despite high rates of chronic pain among their patients, opioid agonist treatment (OAT) counselors report an absence of training to manage chronic pain.: Methods: A multidisciplinary team developed a tailored training for counselors to ... ...

Abstract	Background: Despite high rates of chronic pain among their patients, opioid agonist treatment (OAT) counselors report an absence of training to manage chronic pain. Methods: A multidisciplinary team developed a tailored training for counselors to screen and address chronic pain via a brief psychosocial intervention, and implemented it with 52 addiction counselors. Data on knowledge (9 true-false items) as well as attitudes, interest, and perceived ability (scored on 5-point Likert-type scales) were collected from counselors before (pre-test), after (post-test) training, and after 6 months (follow-up). Results: Pre-test knowledge scores varied considerably. Compared to pre-test, mean counselor knowledge scores increased significantly post-training and at follow-up (p's.<05). The training was associated with increases in positive attitudes toward the role of counselors in managing chronic pain, interest in assessing chronic pain, and counselor ability to assess as well as suggest appropriate interventions for pain (all p's <.05). Perceived ability to assess chronic pain and suggest appropriate treatment interventions were higher at follow-up than at pre-test (p's <.05). Conclusions: Findings related to the initial evaluation of this training were promising, and future research is warranted to further examine the efficacy of training drug counselors on psychosocial interventions to manage chronic pain among OAT patients.
MeSH term(s)	Analgesics, Opioid/therapeutic use ; Chronic Pain/drug therapy ; Chronic Pain/therapy ; Counselors/education ; Counselors/psychology ; Female ; Health Knowledge, Attitudes, Practice ; Humans ; Male ; Methadone/therapeutic use ; Opiate Substitution Treatment ; Pain Management/methods ; Pain Management/psychology ; Pilot Projects ; Program Evaluation ; Psychotherapy/education
Chemical Substances	Analgesics, Opioid ; Methadone (UC6VBE7V1Z)
Language	English
Publishing date	2018-03-09
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1458030-5
ISSN	1547-0164 ; 0889-7077
ISSN (online)	1547-0164
ISSN	0889-7077
DOI	10.1080/08897077.2018.1449052
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Article ; Online: Are Smoking Cessation Treatments Associated with Suicidality Risk? An Overview

J. Kim Penberthy / J. Morgan Penberthy / Marcus R. Harris / Sonali Nanda / Jennifer Ahn / Caridad Ponce Martinez / Apule O. Osika / Zoe A. Slepian / Justin C. Forsyth / J. Andrew Starr / Jennifer E. Farrell / Joshua N. Hook

Substance Abuse: Research and Treatment, Vol 2016, Iss 10, Pp 19-

2016 Volume 30

Keywords	Public aspects of medicine ; RA1-1270
Language	English
Publishing date	2016-04-01T00:00:00Z
Publisher	SAGE Publishing
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Are Smoking Cessation Treatments Associated with Suicidality Risk? An Overview.

Penberthy, J Kim / Penberthy, J Morgan / Harris, Marcus R / Nanda, Sonali / Ahn, Jennifer / Martinez, Caridad Ponce / Osika, Apule O / Slepian, Zoe A / Forsyth, Justin C / Starr, J Andrew / Farrell, Jennifer E / Hook, Joshua N

Substance abuse : research and treatment

2016 Volume 10, Page(s) 19–30

Abstract: Risk of suicidality during smoking cessation treatment is an important, but often overlooked, aspect of nicotine addiction research and treatment. We explore the relationship between smoking cessation interventions and suicidality and explore common ... ...

Abstract	Risk of suicidality during smoking cessation treatment is an important, but often overlooked, aspect of nicotine addiction research and treatment. We explore the relationship between smoking cessation interventions and suicidality and explore common treatments, their associated risks, and effectiveness in promoting smoking reduction and abstinence. Although active smokers have been reported to have twofold to threefold increased risk of suicidality when compared to nonsmokers,1-4 research regarding the safest way to stop smoking does not always provide clear guidelines for practitioners wishing to advise their patients regarding smoking cessation strategies. In this article, we review pharmacological and cognitive behavioral therapy (CBT) options that are available for people seeking to quit smoking, focusing on the relationship between the ability of these therapies to reduce smoking behavior and promote abstinence and suicidality risks as assessed by reported suicidality on validated measures, reports of suicidal ideation, behaviors, actual attempts, or completed suicides. Pharmacotherapies such as varenicline, bupropion, and nicotine replacement, and CBTs, including contextual CBT interventions, have been found to help reduce smoking rates and promote and maintain abstinence. Suicidality risks, while present when trying to quit smoking, do not appear to demonstrate a consistent or significant rise associated with use of any particular smoking cessation pharmacotherapy or CBT/contextual CBT intervention reviewed.
Language	English
Publishing date	2016-04-12
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1458030-5
ISSN	1547-0164 ; 1178-2218 ; 0889-7077
ISSN (online)	1547-0164
ISSN	1178-2218 ; 0889-7077
DOI	10.4137/SART.S33389
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Article ; Online: Are Smoking Cessation Treatments Associated with Suicidality Risk? An Overview

Substance Abuse: Research and Treatment, Vol

2016 Volume 10

Abstract	Risk of suicidality during smoking cessation treatment is an important, but often overlooked, aspect of nicotine addiction research and treatment. We explore the relationship between smoking cessation interventions and suicidality and explore common treatments, their associated risks, and effectiveness in promoting smoking reduction and abstinence. Although active smokers have been reported to have twofold to threefold increased risk of suicidality when compared to nonsmokers, 1 4 research regarding the safest way to stop smoking does not always provide clear guidelines for practitioners wishing to advise their patients regarding smoking cessation strategies. In this article, we review pharmacological and cognitive behavioral therapy (CBT) options that are available for people seeking to quit smoking, focusing on the relationship between the ability of these therapies to reduce smoking behavior and promote abstinence and suicidality risks as assessed by reported suicidality on validated measures, reports of suicidal ideation, behaviors, actual attempts, or completed suicides. Pharmacotherapies such as varenicline, bupropion, and nicotine replacement, and CBTs, including contextual CBT interventions, have been found to help reduce smoking rates and promote and maintain abstinence. Suicidality risks, while present when trying to quit smoking, do not appear to demonstrate a consistent or significant rise associated with use of any particular smoking cessation pharmacotherapy or CBT/contextual CBT intervention reviewed.
Keywords	Public aspects of medicine ; RA1-1270
Language	English
Publishing date	2016-01-01T00:00:00Z
Publisher	SAGE Publishing
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Resistencia bacteriana

Fernando Fernández Riverón / Jorge López Hernández / Laida María Ponce Martínez / Caridad Machado Betarte

Revista Cubana de Medicina Militar, Vol 32, Iss 1, p

2003

Abstract: Se realizó una revisión del grave problema de la resistencia bacteriana y la inquietud que por su causa se tiene en muchos países y en organizaciones internacionales de salud. Se expone el concepto, clasificación y se describen las modalidades genéticas ... ...

Abstract	Se realizó una revisión del grave problema de la resistencia bacteriana y la inquietud que por su causa se tiene en muchos países y en organizaciones internacionales de salud. Se expone el concepto, clasificación y se describen las modalidades genéticas que intervienen en su adquisición y trasmisión. Se señalan los complejos mecanismos mediante los cuales las bacterias inactivan los agentes antimicrobianos y se puntualizan las medidas actuales que se consideran más efectivas para la prevención de estas. A review of the serious problem of bacterial resistance and of the concern it arises in many countries and international health organizations is made. The concept and classification are explained and the genetic modalities taking part in their acquisition and transmission are described. The mechanical complexes by which bacteria inactivate the antimicrobial agents are stressed and emphasis is made on the most effective current measures to prevent them.
Keywords	RESISTENCIA MICROBIANA A LAS DROGAS ; ANTIBIOTICOS ; INFECCIONES BACTERIANAS ; DRUG RESISTANCE ; MICROBIAL ; ANTIBIOTICS ; BACTERIAL INFECTIONS ; Medicine (General) ; R5-920 ; Medicine ; R ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Language	Spanish
Publishing date	2003-03-01T00:00:00Z
Publisher	ECIMED
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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