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  1. Article ; Online: ZBTB16::RARA variant acute promyelocytic leukemia (vAPL) treated with gemtuzumab ozogamicin (GO) with unique pathology and genetic findings.

    Kassem, Alaa M / Keinath, Melissa C / Adler, Jason A / Gadde, Ramya / Tomlinson, Benjamin K / Shetty, Shashirekha

    British journal of haematology

    2023  Volume 202, Issue 6, Page(s) 1077–1078

    MeSH term(s) Humans ; Leukemia, Promyelocytic, Acute/drug therapy ; Leukemia, Promyelocytic, Acute/genetics ; Leukemia, Promyelocytic, Acute/pathology ; Gemtuzumab/therapeutic use ; Antibodies, Monoclonal, Humanized/therapeutic use ; Antibodies, Monoclonal ; Aminoglycosides ; Leukemia, Myeloid, Acute ; Promyelocytic Leukemia Zinc Finger Protein
    Chemical Substances Gemtuzumab (93NS566KF7) ; Antibodies, Monoclonal, Humanized ; Antibodies, Monoclonal ; Aminoglycosides ; ZBTB16 protein, human (147855-37-6) ; Promyelocytic Leukemia Zinc Finger Protein
    Language English
    Publishing date 2023-07-26
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.18950
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uh III Zs.182: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Single-Surgeon in Vivo Experience with the Zeiss QEVO Microinspection Tool: An Analysis of Its Use for Extending the Reach of Operative Visualization.

    Tomlinson, Samuel B / Hendricks, Benjamin K / Cohen-Gadol, Aaron

    World neurosurgery

    2021  Volume 147, Page(s) 268–272

    Abstract: The operating microscope is a foundational tool in modern neurosurgery. Operating microscopes serve increasingly as the lynchpin for highly sophisticated visualization platforms incorporating many complementary technologies. The Zeiss QEVO ... ...

    Abstract The operating microscope is a foundational tool in modern neurosurgery. Operating microscopes serve increasingly as the lynchpin for highly sophisticated visualization platforms incorporating many complementary technologies. The Zeiss QEVO microinspection tool is a 45-degree viewing endoscopic instrument integrated into the Zeiss KINEVO 900 operating microscope (Carl Zeiss AG, Oberkochen, Germany). The QEVO tool enables surgeons to "look around the corners" of the surgical field to optimize visualization within tight operative corridors. In this article, we document our experience using the QEVO microinspection tool in a series of complex cranial neurosurgery procedures. This report focuses on the handling, visualization, and overall utility of the QEVO tool for achieving optimal visualization in deep cranial corridors.
    MeSH term(s) Craniotomy/instrumentation ; Craniotomy/methods ; Ergonomics ; Humans ; Microscopy/instrumentation ; Microsurgery/instrumentation ; Microsurgery/methods ; Neuroendoscopes ; Neuroendoscopy/methods ; Neurosurgical Procedures/instrumentation ; Neurosurgical Procedures/methods
    Language English
    Publishing date 2021-05-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2020.12.036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1159: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: In Reply to the Letter to the Editor Regarding "Immersive Three-Dimensional Modeling and Virtual Reality for Enhanced Visualization of Operative Neurosurgical Anatomy".

    Tomlinson, Samuel B / Hendricks, Benjamin K / Cohen-Gadol, Aaron

    World neurosurgery

    2020  Volume 137, Page(s) 502

    MeSH term(s) Neurosurgery ; User-Computer Interface ; Virtual Reality
    Language English
    Publishing date 2020-06-26
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2020.02.177
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1159: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Editorial. Innovations in neurosurgical education during the COVID-19 pandemic: is it time to reexamine our neurosurgical training models?

    Tomlinson, Samuel B / Hendricks, Benjamin K / Cohen-Gadol, Aaron A

    Journal of neurosurgery

    2020  , Page(s) 1–2

    Keywords covid19
    Language English
    Publishing date 2020-04-17
    Publishing country United States
    Document type Editorial
    ZDB-ID 3089-2
    ISSN 1933-0693 ; 0022-3085
    ISSN (online) 1933-0693
    ISSN 0022-3085
    DOI 10.3171/2020.4.JNS201012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uk I Zs.135: Show issues Location:
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  5. Article ; Online: COVID-19 presenting as a viral exanthem and detected during admission prescreening in a hematopoietic cell transplant recipient.

    Ahmed, Nausheen / Lima, Marcos de / Rohr, Bethany R / Tomlinson, Benjamin K

    Hematology, transfusion and cell therapy

    2020  Volume 42, Issue 3, Page(s) 215–217

    Keywords covid19
    Language English
    Publishing date 2020-06-13
    Publishing country Brazil
    Document type Case Reports
    ISSN 2531-1387
    ISSN (online) 2531-1387
    DOI 10.1016/j.htct.2020.06.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Immersive Three-Dimensional Modeling and Virtual Reality for Enhanced Visualization of Operative Neurosurgical Anatomy.

    Tomlinson, Samuel B / Hendricks, Benjamin K / Cohen-Gadol, Aaron

    World neurosurgery

    2019  Volume 131, Page(s) 313–320

    Abstract: Learning the endless intricacies of operative neurosurgical anatomy requires that surgeons complement their intraoperative experiences with a variety of educational resources. In the past 2 decades, rapid improvements in digital graphics and computing ... ...

    Abstract Learning the endless intricacies of operative neurosurgical anatomy requires that surgeons complement their intraoperative experiences with a variety of educational resources. In the past 2 decades, rapid improvements in digital graphics and computing power have enabled a new generation of 3-dimensional (3D) virtual resources that overcome limitations of more traditional 2-dimensional materials. Today, dozens of immersive 3D visualization platforms exist for applications such as learning neuroanatomy, simulating operative techniques, and planning surgical interventions with patient-specific models. The purpose of this article is to identify current applications of 3D digital modeling and virtual reality in neurosurgery. In addition, we showcase a new series of freely available 3D virtual-reality models created to assist in learning complex cranial anatomy. We anticipate these models to have a wide range of educational, clinical, and research applications. Three-dimensional visualization is poised to modernize the ways we learn and teach neurosurgical anatomy outside of the operating room. Future generations of neurosurgeons are expected to benefit from these technologies from the earliest stages of training.
    MeSH term(s) Equipment Design ; Humans ; Imaging, Three-Dimensional ; Internet ; Internship and Residency/methods ; Models, Anatomic ; Neurosurgical Procedures/education ; Pedicle Screws ; Printing, Three-Dimensional ; Skull/anatomy & histology ; Virtual Reality
    Language English
    Publishing date 2019-10-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2019.06.081
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1159: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Stereoelectroencephalography before 2 years of age.

    Rahman, Raphia K / Tomlinson, Samuel B / Katz, Joshua / Galligan, Kathleen / Madsen, Peter J / Tucker, Alexander M / Kessler, Sudha Kilaru / Kennedy, Benjamin C

    Neurosurgical focus

    2022  Volume 53, Issue 4, Page(s) E3

    Abstract: Objective: Stereoelectroencephalography (SEEG) is a widely used technique for localizing seizure onset zones prior to resection. However, its use has traditionally been avoided in children under 2 years of age because of concerns regarding pin fixation ... ...

    Abstract Objective: Stereoelectroencephalography (SEEG) is a widely used technique for localizing seizure onset zones prior to resection. However, its use has traditionally been avoided in children under 2 years of age because of concerns regarding pin fixation in the immature skull, intraoperative and postoperative electrode bolt security, and stereotactic registration accuracy. In this retrospective study, the authors describe their experience using SEEG in patients younger than 2 years of age, with a focus on the procedure's safety, feasibility, and accuracy as well as surgical outcomes.
    Methods: A retrospective review of children under 2 years of age who had undergone SEEG while at Children's Hospital of Philadelphia between November 2017 and July 2021 was performed. Data on clinical characteristics, surgical procedure, imaging results, electrode accuracy measurements, and postoperative outcomes were examined.
    Results: Five patients younger than 2 years of age underwent SEEG during the study period (median age 20 months, range 17-23 months). The mean age at seizure onset was 9 months. Developmental delay was present in all patients, and epilepsy-associated genetic diagnoses included tuberous sclerosis (n = 1), KAT6B (n = 1), and NPRL3 (n = 1). Cortical lesions included tubers from tuberous sclerosis (n = 1), mesial temporal sclerosis (n = 1), and cortical dysplasia (n = 3). The mean number of placed electrodes was 11 (range 6-20 electrodes). Bilateral electrodes were placed in 1 patient. Seizure onset zones were identified in all cases. There were no SEEG-related complications, including skull fracture, electrode misplacement, hemorrhage, infection, cerebrospinal fluid leakage, electrode pullout, neurological deficit, or death. The mean target point error for all electrodes was 1.0 mm. All patients proceeded to resective surgery, with a mean follow-up of 21 months (range 8-53 months). All patients attained a favorable epilepsy outcome, including Engel class IA (n = 2), IC (n = 1), ID (n = 1), and IIA (n = 1).
    Conclusions: SEEG can be safely, accurately, and effectively utilized in children under age 2 with good postoperative outcomes using standard SEEG equipment. With minimal modification, this procedure is feasible in those with immature skulls and guides the epilepsy team's decision-making for early and optimal treatment of refractory epilepsy through effective localization of seizure onset zones.
    MeSH term(s) Child ; Child, Preschool ; Drug Resistant Epilepsy/surgery ; Electrodes, Implanted ; Electroencephalography/methods ; Epilepsy/diagnostic imaging ; Epilepsy/surgery ; GTPase-Activating Proteins ; Histone Acetyltransferases ; Humans ; Infant ; Retrospective Studies ; Seizures/surgery ; Stereotaxic Techniques ; Tuberous Sclerosis/surgery
    Chemical Substances GTPase-Activating Proteins ; NPRL3 protein, human ; Histone Acetyltransferases (EC 2.3.1.48) ; KAT6B protein, human (EC 2.3.1.48)
    Language English
    Publishing date 2022-10-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2026589-X
    ISSN 1092-0684 ; 1092-0684
    ISSN (online) 1092-0684
    ISSN 1092-0684
    DOI 10.3171/2022.7.FOCUS22336
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Editorial. Innovations in neurosurgical education during the COVID-19 pandemic: is it time to reexamine our neurosurgical training models?

    Tomlinson, Samuel B / Hendricks, Benjamin K / Cohen-Gadol, Aaron A

    J Neurosurg

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #72112
    Database COVID19

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  9. Article: COVID-19 presenting as a viral exanthem and detected during admission prescreening in a hematopoietic cell transplant recipient

    Ahmed, Nausheen / Lima, Marcos de / Rohr, Bethany R / Tomlinson, Benjamin K
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #597753
    Database COVID19

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  10. Book ; Online: COVID-19 presenting as a viral exanthem and detected during admission prescreening in a hematopoietic cell transplant recipient

    Ahmed, Nausheen / Lima, Marcos de / Rohr, Bethany R. / Tomlinson, Benjamin K.

    Hematology, Transfusion and Cell Therapy v.42 n.3 2020

    2020  

    Keywords covid19
    Language English
    Publishing date 2020-09-01
    Publisher Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular (ABHH)
    Publishing country br
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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