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Article ; Online: Opportunities for ABA intervention in Phelan-McDermid syndrome.

Schroeder, Kate A / Witts, Benjamin N / Traub, Michele R

International journal of developmental disabilities

2021 Volume 68, Issue 6, Page(s) 984–989

Abstract: Phelan-McDermid syndrome (PMS), also called 22q13.3 deletion syndrome, is a rare genetic disorder affecting at least 2,000 people worldwide (Phelan-McDermid Syndrome Foundation, 2019, How rare is Phelan-McDermid?). PMS has many distinguishing ... ...

Abstract	Phelan-McDermid syndrome (PMS), also called 22q13.3 deletion syndrome, is a rare genetic disorder affecting at least 2,000 people worldwide (Phelan-McDermid Syndrome Foundation, 2019, How rare is Phelan-McDermid?). PMS has many distinguishing characteristics and many medical specialties have been recommended to treat the clinical features. While many therapies, including behavioral therapy, have been speculated to be beneficial in treating PMS, there is little known regarding their effectiveness [Costales, J. L. and Kolevzon, A. 2015. Phelan-McDermid syndrome and SHANK3: Implications for treatment. Neurotherapeutics: The Journal of the American Society for Experimental Neurotherapeutics, 12, 620-630.]. Behavior analysis has the capability to help in many areas of treatment for PMS either directly through, for example, behavior treatment to address aggressive behavior, or through collaborating with other specialties treating PMS by combining, for example, behavioral principles in the alleviation of medical issues such as constipation. Currently, there is a role for the behavior analyst to expand our field and identify effective treatments for those with PMS while we wait for a cure. In this paper, we discuss how medical considerations may affect behavior interventions and make recommendations for the behavior analyst working with PMS.
Language	English
Publishing date	2021-03-09
Publishing country	England
Document type	Journal Article
ZDB-ID	2625980-1
ISSN	2047-3877 ; 2047-3869
ISSN (online)	2047-3877
ISSN	2047-3869
DOI	10.1080/20473869.2021.1895698
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Article ; Online: New micro-hole zone catheter reduces residual urine and mucosal microtrauma in a lower urinary tract model.

Schrøder, Brit / Tentor, Fabio / Miclăuş, Teodora / Stærk, Kristian / Andersen, Thomas Emil / Spinelli, Michele / Rendeli, Claudia / Del Popolo, Giulio / Bagi, Per / Nielsen, Lene Feldskov

Scientific reports

2024 Volume 14, Issue 1, Page(s) 2268

Abstract: Urinary tract infections (UTIs) are the main complication associated with clean intermittent catheterization (CIC) and are facilitated by post-void residual urine and trauma to the mucosa during voiding. The risk of UTI may be diminished by reducing the ... ...

Abstract	Urinary tract infections (UTIs) are the main complication associated with clean intermittent catheterization (CIC) and are facilitated by post-void residual urine and trauma to the mucosa during voiding. The risk of UTI may be diminished by reducing the residual volumes and preventing microtrauma caused by mucosal suction through the eyelets of conventional eyelet catheters (CEC). A new micro-hole zone catheter (MHZC) was developed and tested in an ex vivo porcine lower urinary tract model and in vivo, in pigs, against a CEC. It was shown that, irrespective of the micro-hole diameter, the new catheter ensured increased flowrates and significantly lower residual volumes at the first flow-stop. Furthermore, with a micro-hole diameter of 0.4 mm, mucosal suction was virtually eliminated, regardless of the insertion depth or simulated intra-abdominal pressure mimicking sitting or standing humans. Pressure profile experiments and endoscopy studies indicated that the bladder gradually folds against the drainage tip of the new catheter, without blocking the flow, and, unlike with the CEC, sharp pressure variations and flow-stops did not occur during voiding. The MHZC outperformed the CEC in all tested scenarios and decreased residual volumes, thus potentially decreasing the risk of UTIs.
MeSH term(s)	Humans ; Animals ; Swine ; Urinary Bladder ; Urinary Retention ; Urinary Tract Infections/prevention & control ; Urinary Tract Infections/etiology ; Intermittent Urethral Catheterization/adverse effects ; Catheters/adverse effects
Language	English
Publishing date	2024-01-27
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-52505-6
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Article ; Online: Rewarding behavior with a sweet food strengthens its valuation.

Bauer, Jan M / Schröder, Marina / Vecchi, Martina / Bake, Tina / Dickson, Suzanne L / Belot, Michèle

PloS one

2021 Volume 16, Issue 4, Page(s) e0242461

Abstract: Sweet foods are commonly used as rewards for desirable behavior, specifically among children. This study examines whether such practice may contribute to reinforce the valuation of these foods. Two experiments were conducted, one with children, the other ...

Abstract	Sweet foods are commonly used as rewards for desirable behavior, specifically among children. This study examines whether such practice may contribute to reinforce the valuation of these foods. Two experiments were conducted, one with children, the other with rats. The first study, conducted with first graders (n = 214), shows that children who receive a food reward for performing a cognitive task subsequently value the food more compared to a control group who received the same food without performing any task. The second study, conducted on rats (n = 64), shows that rewarding with food also translates into higher calorie intake over a 24-hour period. These results suggest that the common practice of rewarding children with calorie-dense sweet foods is a plausible contributing factor to obesity and might therefore be ill advised.
MeSH term(s)	Animals ; Child ; Eating/psychology ; Energy Intake/physiology ; Feeding Behavior/psychology ; Female ; Food ; Food Preferences/psychology ; Humans ; Male ; Obesity/psychology ; Rats ; Rats, Sprague-Dawley ; Reinforcement, Psychology ; Reward ; Taste/physiology
Language	English
Publishing date	2021-04-14
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0242461
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book ; Online: Equitable Research Partnerships : A Global Code of Conduct to Counter Ethics Dumping

Schroeder, Doris / Chatfield, Kate / Singh, Michelle / Chennells, Roger / Herissone-Kelly, Peter

2019

Keywords	Development studies ; Ethics & moral philosophy ; International relations ; Human rights ; Business ethics & social responsibility ; Corporate governance ; Philosophy ; Research-Moral and ethical aspects ; Economic development ; Business ethics
Size	1 electronic resource (122 pages)
Publisher	Springer Nature
Publishing place	Cham
Document type	Book ; Online
Note	English ; Open Access
HBZ-ID	HT021028152
ISBN	978-3-030-15745-6 ; 3-030-15745-8
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Book ; Online: Equitable Research Partnerships

Schroeder, Doris / Chatfield, Kate / Singh, Michelle / Chennells, Roger / Herissone-Kelly, Peter

A Global Code of Conduct to Counter Ethics Dumping

(SpringerBriefs in Research and Innovation Governance)

2019

Author's details	by Doris Schroeder, Kate Chatfield, Michelle Singh, Roger Chennells, Peter Herissone-Kelly
Series title	SpringerBriefs in Research and Innovation Governance
Keywords	Research-Moral and ethical aspec ; Corporate governance ; Economic development ; International relations ; Business ethics ; Wissenschaftliche Kooperation ; Wissenschaftsethik ; Verhaltenskodex
Subject	Code of conduct ; Verhaltenscodex ; Verhaltensrichtlinie ; Wissenschaft ; Forschungsethik ; Forschung ; Wissenschaftliche Zusammenarbeit ; Wissenschaftskooperation ; Wissenschaftskollaboration
Subject code	174.9
Language	English
Size	1 Online-Ressource (XIX, 122 p. 12 illus., 11 illus. in color)
Publisher	Springer International Publishing ; Imprint: Springer
Publishing place	Cham
Document type	Book ; Online
HBZ-ID	HT020076139
ISBN	978-3-030-15745-6 ; 9783030157449 ; 9783030157463 ; 3-030-15745-8 ; 303015744X ; 3030157466
DOI	10.1007/978-3-030-15745-6
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article: Sustained Effectiveness of Benralizumab in Naïve and Biologics-Experienced Severe Eosinophilic Asthma Patients: Results from the ANANKE Study.

Cameli, Paolo / Aliani, Maria / Altieri, Elena / Bracciale, Pietro / Brussino, Luisa / Caiaffa, Maria Filomena / Canonica, Giorgio Walter / Caruso, Cristiano / Centanni, Stefano / D'Amato, Maria / De Michele, Fausto / Del Giacco, Stefano / Di Marco, Fabiano / Pelaia, Girolamo / Rogliani, Paola / Romagnoli, Micaela / Schino, Pietro / Schroeder, Jan Walter / Senna, Gianenrico /

Vultaggio, Alessandra / Benci, Marco / Boarino, Silvia / Menzella, Francesco

Journal of asthma and allergy

2024 Volume 17, Page(s) 273–290

Abstract: Purpose: Severe eosinophilic asthma (SEA) patients often present overlapping inflammatory features rendering them eligible for multiple biologic therapies; switching biologic treatment is a strategy adopted to optimize asthma control when patients show ... ...

Abstract	Purpose: Severe eosinophilic asthma (SEA) patients often present overlapping inflammatory features rendering them eligible for multiple biologic therapies; switching biologic treatment is a strategy adopted to optimize asthma control when patients show partial or no response to previous biologics. Patients and methods: ANANKE is a retrospective, multicenter Italian study (NCT04272463). Here, we outline the characteristics and long-term clinical outcomes in naïve-to-biologics and biologics-experienced patients treated with benralizumab for up to 96 weeks. Bio-experienced patients were split into omalizumab and mepolizumab subsets according to the type of biologic previously used. Results: A total of 124 (76.5%) naïve and 38 (23.5%) bio-experienced patients were evaluated at index date; 13 patients (34.2%) switched from mepolizumab, 21 patients (55.3%) switched from omalizumab, and four patients (10.5%) received both biologics. The mepolizumab subset was characterized by the longest SEA duration (median of 4.6 years), the highest prevalence of chronic rhinosinusitis with nasal polyposis (CRSwNP) (76.5%), and the greatest oral corticosteroid (OCS) daily dosage (median of 25 mg prednisone equivalent). The omalizumab group showed the highest severe annual exacerbation rate (AER) (1.70). At 96 weeks, treatment with benralizumab reduced any and severe AER by more than 87% and 94%, respectively, across all groups. Lung function was overall preserved, with major improvements observed in the mepolizumab group, which also revealed a 100% drop of the median OCS dose. Asthma Control Test (ACT) score improved in the naïve group while its increment was more variable in bio-experienced patients; among these, a marked difference was noticed between omalizumab and mepolizumab subsets (median ACT score of 23.5 and 18, respectively). Conclusion: Benralizumab promotes durable and profound clinical benefits in naïve and bio-experienced groups, indicating that a nearly complete depletion of eosinophils is highly beneficial in the control of SEA, independently of previous biologic use.
Language	English
Publishing date	2024-03-27
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2494877-9
ISSN	1178-6965
ISSN	1178-6965
DOI	10.2147/JAA.S438981
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Article ; Online: The effects of acute exercise on memory of cognitively healthy seniors: A systematic review.

Griebler, Nathália / Schröder, Nadja / Artifon, Milena / Frigotto, Michele / Pietta-Dias, Caroline

Archives of gerontology and geriatrics

2021 Volume 99, Page(s) 104583

Abstract: Objective: To systematically review the acute effects of physical exercise on memory in healthy elderly people.: Methods: The present study consists of a systematic review based on the criteria of the Preferred Reporting Items for Systematic Reviews ... ...

Abstract	Objective: To systematically review the acute effects of physical exercise on memory in healthy elderly people. Methods: The present study consists of a systematic review based on the criteria of the Preferred Reporting Items for Systematic Reviews and Meta - Analyzes (PRISMA). Searches were carried out in the health databases: PubMed (Medline); ScienceDirect (Elsevier); SciELO, Cochrane and LILACS, including articles published until April 2021. The included studies should be randomized clinical trials in healthy elderly populations, have acute physical exercise as an intervention compared to another type of exercise or to a control session, and assess memory as an outcome. Results: A total of 3711 records were found in the databases. After reading titles and abstracts, 27 full texts of studies were selected. A total of 10 records met the inclusion criteria and were considered eligible for qualitative analysis. The total sample consisted of 465 healthy individuals, of both sexes, aged between 60 and 95 years. The aerobic and resistance exercises performed at low (7-11 Borg scale, 54% FCM or 40-54% 1RM) and moderate intensities (12-15 Borg scale, 50-70% FCM and 55-75% 1RM) lead to memory improvement in cognitively healthy elderly people. Conclusions: The paucity of studies with this population, using higher exercise intensities, as well as a reduced variety of memory tests, were limiting factors. Maintaining a training routine is important, in order to preserve physical and mental health. More studies addressing the effects of exercise protocols in healthy individuals are warranted.
MeSH term(s)	Aged ; Aged, 80 and over ; Exercise ; Exercise Therapy ; Female ; Humans ; Male
Language	English
Publishing date	2021-11-19
Publishing country	Netherlands
Document type	Journal Article ; Review ; Systematic Review
ZDB-ID	603162-6
ISSN	1872-6976 ; 0167-4943
ISSN (online)	1872-6976
ISSN	0167-4943
DOI	10.1016/j.archger.2021.104583
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Article: The spillover effects of monitoring

Belot, Michèle / Schröder, Marina

Management science : journal of the Institute for Operations Research and the Management Sciences Vol. 62, No. 1 , p. 37-45

a field experiment

2016 Volume 62, Issue 1, Page(s) 37–45

Author's details	Michèle Belot (School of Economics, University of Edinburgh, Edinburgh, United Kingdom), Marina Schröder (Faculty of Management, Economics and Social Sciences, University of Cologne, Cologne, Germany)
Keywords	counterproductive behavior ; monitoring ; field experiment
Language	English
Publisher	INFORMS
Publishing place	Hanover, Md
Document type	Article
ZDB-ID	206345-1 ; 2023019-9
ISSN	1526-5501 ; 0025-1909
ISSN (online)	1526-5501
ISSN	0025-1909
Database	ECONomics Information System

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Article ; Online: Direct and inverse identification of constitutive parameters from the structure of soft tissues. Part 2: dispersed arrangement of collagen fibers.

von Hoegen, Markus / Marino, Michele / Schröder, Jörg / Wriggers, Peter

Biomechanics and modeling in mechanobiology

2019 Volume 18, Issue 4, Page(s) 897–920

Abstract: This paper investigates on the relationship between the arrangement of collagen fibers within soft tissues and parameters of constitutive models. Starting from numerical experiments based on biaxial loading conditions, the study addresses both the direct ...

Abstract	This paper investigates on the relationship between the arrangement of collagen fibers within soft tissues and parameters of constitutive models. Starting from numerical experiments based on biaxial loading conditions, the study addresses both the direct (from structure to mechanics) and the inverse (from mechanics to structure) problems, solved introducing optimization problems for model calibration and regression analysis. A campaign of parametric analyses is conducted in order to consider fibers distributions with different main orientation and angular dispersion. Different anisotropic constitutive models are employed, accounting for fibers dispersion either with a generalized structural approach or with an increasing number of strain energy terms. Benchmark data sets, toward which constitutive models are fitted, are built by employing a multiscale description of fiber nonlinearities and accounting for fibers dispersion with an angular integration method. Results show how the optimal values of constitutive parameters obtained from model calibration vary as a function of fibers arrangement and testing protocol. Moreover, the fitting capabilities of constitutive models are discussed. A novel strategy for model calibration is also proposed, in order to obtain a robust accuracy with respect to different loading conditions starting from a low number of mechanical tests. Furthermore, novel results useful for the inverse determination of the mean angle and the variance of fibers distribution are obtained. Therefore, the study contributes: to better design procedures for model calibration; to account for mechanical alterations due to remodeling mechanisms; and to gain structural information in a nondestructive way.
MeSH term(s)	Algorithms ; Fibrillar Collagens/physiology ; Models, Biological ; Organ Specificity ; Regression Analysis
Chemical Substances	Fibrillar Collagens
Language	English
Publishing date	2019-02-09
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2093052-5
ISSN	1617-7940 ; 1617-7959
ISSN (online)	1617-7940
ISSN	1617-7959
DOI	10.1007/s10237-019-01119-3
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Article ; Online: Phelgmasia Cerulea Dolens Diagnosed by Point-of-Care Ultrasound.

Schroeder, Michele / Shorette, Amanda / Singh, Sukhdeep / Budhram, Gavin

Clinical practice and cases in emergency medicine

2017 Volume 1, Issue 2, Page(s) 104–107

Abstract: Phlegmasia cerulea dolens (PCD) is a rare entity that is associated with significant morbidity and mortality, including limb ischemia and pulmonary embolism. Point-of-care ultrasound (POCUS) can expedite the diagnosis, leading to earlier life- and limb- ... ...

Abstract	Phlegmasia cerulea dolens (PCD) is a rare entity that is associated with significant morbidity and mortality, including limb ischemia and pulmonary embolism. Point-of-care ultrasound (POCUS) can expedite the diagnosis, leading to earlier life- and limb-saving treatment. Although primarily used for assessing for the presence of deep venous thrombosis, in the appropriate clinical setting POCUS can also be used to diagnosis PCD as well as to distinguish between venous and arterial occlusion, which can lead to a difference in management. We present a case of phlegmasia cerulea dolens after mild trauma in a patient with an underlying hypercoagulability disorder diagnosed by an emergency physician using POCUS, which expedited treatment with catheter-directed thrombolytic therapy.
Language	English
Publishing date	2017-03-13
Publishing country	United States
Document type	Case Reports
ISSN	2474-252X
ISSN (online)	2474-252X
DOI	10.5811/cpcem.2016.12.32716
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